• 대한수의학회지
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• 제58권4호
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• pp.201-209
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• 2018

Canine mammary tumors are among the most frequently observed cutaneous tumors in female dogs. Cancer stem cells (CSCs), referred to as tumor-initiating cells, are thought to have properties similar to normal stem cells such as the ability to self-renewal and to differentiate into various cell types. Biological understanding of CSCs and the critical pathways involved in their maintenance are important in research and therapy for mammary tumors. We conducted the present study on sphere formation from REM134 cells by using methylcellulose to produce tumorspheres on a large scale and compared the specific markers of the spheres-formed and plating-cultured REM134 cells. The results revealed that the tumorspheres cultured in methylcellulose had higher seeding density and improved morphology compared to those produced in normal sphere formation medium. Expression levels of stemness markers and CSC-related markers were higher in tumorsphere-forming cells than in plating-cultured cells. Subsequently, we transplanted the tumorsphere-forming and plating-cultured cells into female nude mice to examine their tumorigenic potential. Tumor volume increased rapidly in mice transplanted with tumorsphere-derived cells compared to plating-cultured cells. We observed a novel sphere-forming condition for REM134 cells and showed that REM134 cell tumorspheres can exhibit improved CSC properties.

• Advances in materials Research
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• 제11권4호
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• pp.299-330
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• 2022

This review article highlights the physical, mechanical, and chemical properties of coconut shells, and the fresh and hardened properties of the coconut shell concrete are summarized and were compared with other types of aggregates. Furthermore, the structural behavior in terms of flexural, shear, and torsion was also highlighted, with other properties including shrinkage, elastic modulus, and permeability of the coconut shell concrete. Based on the reviewed literature, concrete containing coconut shell as coarse aggregate with normal sand as fine showed the 28-day compressive strength between 2 and 36 MPa with the dried density range of 1865 to 2300 kg/m³. Coconut shell concretes showed a 28-day modulus of rupture and splitting tensile strength values in the ranges of 2.59 to 8.45 MPa and 0.8 to 3.70 MPa, respectively, and these values were in the range of 5-20% of the compressive strength. The flexural behavior of CSC was found similar to other types of lightweight concrete. There were no horizontal cracks on beams which indicate no bond failure. Whereas, the diagonal shear failure was prominent in beams with no shear reinforcements while flexural failure mode was seen in beams having shear reinforcement. Under torsion, CSC beams behave like conventional concrete. Finally, future recommendations are also suggested in this study to investigate the innovative lightweight aggregate concrete based on the environmental and financial design factors.

• Restorative Dentistry and Endodontics
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• 제46권1호
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• pp.3.1-3.14
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• 2021

Objectives: This study aimed to evaluate the interface between a calcium silicate cement (CSC), Biodentine and dental adhesives in terms of sealing ability. Materials and Methods: Microleakage test: 160 standardized class II cavities were prepared on 80 extracted human molars. The cavities were filled with Biodentine and then divided into 2 experimental groups according to the time of restoration: composite resin obturation 15 minutes after Biodentine handling (D0); restoration after 7 days (D7). Each group was then divided into 8 subgroups (n = 5) according to the adhesive system used: etch-and-rinse adhesive (Prime & Bond); self-etch adhesive 2 steps (Optibond XTR and Clearfil SE Bond); self-etch adhesive 1 step (Xeno III, G-aenial Bond, and Clearfil Tri-S Bond); and universal used as etch-and-rinse or self-etch (ScotchBond Universal ER or SE). After thermocycling, the teeth were immersed in a silver nitrate solution, stained, longitudinally sectioned, and the Biodentine/adhesive percolation was quantified. Scanning electron microscopic observations: Biodentine/adhesive interfaces were observed. Results: A tendency towards less microleakage was observed when Biodentine was etched (2.47%) and when restorations were done without delay (D0: 4.31%, D7: 6.78%), but this was not significant. The adhesives containing 10-methacryloyloxydecyl dihydrogen phosphate monomer showed the most stable results at both times studied. All Biodentine/adhesive interfaces were homogeneous and regular. Conclusions: The good sealing of the CSC/adhesive interface is not a function of the system adhesive family used or the cement maturation before restoration. Biodentine can be used as a dentine substitute.

• 한국건축시공학회지
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• 제24권3호
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• pp.285-295
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• 2024

본 연구에서는 500℃·hr의 증기양생을 실시한 OPC 페이스트에 대하여 1atm 20% 농도의 CO₂와 5atm 99% 농도의 고농도 CO₂ 조건 하의 촉진 탄산화의 영향평가를 수행하였다. 이를 위하여 XRD, FT-IR을 통한 화학적 분석과 SEM, 압축강도 측정을 통한 물리적 특성 분석을 실시하였다. 그 결과 CO₂ 20% 농도의 상압 탄산화를 수행하는 경우 뚜렷한 내부 조직구조 치밀화 및 압축강도 증진 효과를 관찰할 수 있었고, CO₂ 99% 농도의 5atm 가압 탄산화를 실시할 경우 표면조직구조가 빠르게 치밀해지며 CO₂ 확산침투율이 크게 떨어지게 되어 압축강도 등 유의미한 수준의 물리적 특성 개선이 일어날 정도의 탄산화를 진행할 수 없었다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 심포지엄 논문집 정보 및 제어부문
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• pp.176-177
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• 2008

곳곳에 산재한 컴퓨터를 시간과 장소에 상관없이 자유롭게 이용함으로써, 편리하고 쾌적한 정보이용환경을 구현하게 해주는 유비쿼터스 사회(Ubiquitous Society)는 동시에 예측 불가능한 위험이 곳곳에 산재한 '고도화된 정보위험사회'로의 진입을 의미한다. 본 논문에서는 인터넷을 통해 날로 지능화 고도화되는 사이버 위협으로부터 정보자산에 대한 안정성 강화와 분산 운영되는 보안관리 시스템(ESM)을 통합 모니터링하여 사이버위협상황에 대한 실시간 감시 대응을 체계적이고 효율적으로 수행하기 위한 K-water 사이보안센터(Cyber Security Center, CSC)를 구축하였으며 이를 통한 신뢰성 잇는 사이버보안체계를 제시하고자 한다.

• 전기학회논문지
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• 제57권10호
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• pp.1726-1730
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• 2008

In this paper, the application schemes for coordinated control system of multiple FACTS were presented to enhance the voltage stability around the metropolitan areas. In order to coordinated control of FACTS devices, f-V analysis method which is one of the indices for voltage stability was performed with real time network data which is transferred from SCADA/EMS system. If the system is unstable after contingencies, the new operation set-point of FACTS would be determined using bus sensitivity from tangent vector at voltage instability point. Otherwise, we would determine the new operation set-point of FACTS for considering economical operation, like as active power loss minimization using Optimal Power Flow algorithm. In simulation, the SCADA/EMS 2007's data are used for studying the coordinated control algorithm of multiple FACTS devices that is installed or will be installed in KOREA power system

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3629-3633
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• 2015

Cancer stem cells (CSCs) are rare subpopulations within tumors which are recognized as culprits in cancer recurrence, drug resistance and metastasis. However, the molecular mechanisms of how CSCs are regulated remain elusive. Kr$\ddot{u}$ppel-like factors (KLFs) are evolutionarily conserved zinc finger-containing transcription factors with diverse functions in cell differentiation, proliferation, embryogenesis and pluripotency. Recent progress has highlighted the significance of KLFs, especially KLF4, in cancer and CSCs. Therefore, for better therapeutics of cancer disease, it is crucial to develop a deeper understanding of the mechanisms of how KLF4 regulate CSC functions. Herein we summarized the current understanding of the transcriptional regulation of K LF4 in CSCs, and discussed the functional implications of targeting CSCs for potential cancer therapeutics.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 The 6th International Symposium of East Asian Resources Recycling Technology
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• pp.437-442
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• 2001

In an integrated steel mill, zinc (Zn) inputs from raw materials and steel scrap are enriched in the dusts and sludges collected from gas and water cleaning systems. The reuse of these dusts and sludges must be controlled within certain limit to avoid Zn accumulation and related operational problems in blast furnace. An integrated system has been established at China Steel Corporation (CSC) to enhance the internal reuse of Zn-containing dust/sludge while keeping Zn input within control lim it. However. the performance of this system has not been very satisfactory until one and half years ago when a rationalization process was initiated. The essence of this rationalization process, the recent improvements in Zn control and dust and sludge reuse are reported and discussed.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 제39회 하계학술대회
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• pp.1176-1177
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• 2008

오늘날 고유가 시대를 맞아 신재생에너지에 대한 관심이 점점 더 증가하는 추세에 있다. 전세계적으로 풍력발전은 신재생에너지를 이용한 여러 발전방식 가운데 가장 각광을 받고 있으며 실용화된 발전방식이다. 풍력발전의 경우 다른 신재생에너지를 이용한 발전원보다 경제성이 있고 용량이 크기 때문에 이미 상당한 용량의 풍력발전단지가 설치되어 운영중에 있으며 향후 더 많은 풍력발전단지가 건설될 예정에 있다. 특히 제주도 지역의 경우 풍력발전단지의 입지조건에 부합되어 많은 풍력발전단지가 건설될 예정에 있으며, 세계적인 추세인 해양풍력발전단지도 건설예정에 있다. 해양풍력단지의 경우 육지에서 약간 떨어진 바다에 풍력발전기를 건설한 후, 육지로 전력을 수송하게 된다. 육지와 해양풍력발전단지의 연계는 여러 방식이 있는데 본 논문에서는 HVDC를 이용한 해양풍력발전단지의 연계에 관한 연구를 진행하였다. HVDC의 경우 전압형과 전류형 HVDC가 있는데 두 가지 방식을 비교분석하여 해양풍력발전단지의 계통 연계에 알맞은 최적의 방식을 도출해본다.

• Computers and Concrete
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• 제20권1호
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• pp.1-10
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• 2017

This paper focuses on the mesh-size dependency in numerical simulations of reinforced concrete (RC) structures subjected to blast loading. A tensile failure criterion that can minimize the mesh-dependency of simulation results is introduced based on the fracture energy theory. In addition, conventional plasticity based damage models for concrete such as the CSC model and the HJC model, which are widely used for blast analyses of concrete structures, are compared with the orthotropic model that adopts the introduced tensile failure criterion in blast tests to verify the proposed criterion. The numerical predictions of the time-displacement relations at the mid-span of RC beams subjected to blast loading are compared with experimental results. The analytical results show that the numerical error according to the change in the finite element mesh size is substantially reduced and the accuracy of the numerical results is improved by applying a unique failure strain value determined by the proposed criterion.