• 한국지반환경공학회 논문집
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• 제21권6호
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• pp.5-11
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• 2020

최근 포항 및 주변 지역에서 지진 발생에 따른 액상화 현상 관측으로 인해 액상화 발생 가능성을 예측하는 연구의 중요성이 대두되고 있다. 액상화 발생 가능성은 지반정보를 활용하여 평가할 수 있는데 평가에 활용되는 전단저항강도비(CRR)값은 두 가지 지반정보인 SPT-N값과 V_s값을 활용하여 결정할 수 있다. 이 두 가지 지반정보를 활용하여 평가한 액상화 발생 가능성의 정확도를 비교하는 연구가 수행된 바 있으며 해당 연구에서는 SPT-N값을 활용한 결과가 V_s값을 활용한 결과보다 정확하다는 결론을 지었다. 또한 V_s값을 활용한 결과의 정확도가 낮은 이유는 V_s값이 액상화에 취약한 심도를 고려하지 않고 일률적으로 12m 심도에서 측정되었기 때문인 것으로 판단하였다. 따라서 본 연구에서는 일률적으로 12m 지점에서 측정된 지반정보의 타당성을 확인하고자 액상화에 취약한 심도에서 측정된 SPT-N값을 V_s값으로 환산하는 총 10가지의 경험식을 활용하여 환산된 V_s값을 통해 액상화 발생 가능성을 평가하고 실제 액상화 발생 결과와 비교하여 정확도를 확인하는 작업을 수행하였다. 그 결과 액상화에 취약한 심도를 고려한 10가지 경우 중 7가지 경우에 대하여 고려하지 않은 결과에 비해 정확도가 높게 나타났다.

• 한국분말재료학회지
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• 제11권2호
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• pp.158-164
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• 2004

W-Cu composite has been used for the applications requiring both high strength, good thermal and electrical conductivity. A graded combination of W and Cu will reduce thermal stress concerned with heat conduction, maintaining good thermal conductivity and high mechanical strength. In the present work, an attempt was made to fabricate continuous W-Cu FGM by preparing the graded porous structure of W skeleton using spark plasma sintering (SPS) process followed by infiltrating Cu. The graded porous structure was prepared at 150$0^{\circ}C$ for 60s under pressure of 15MPa by SPS process using a graphite mold with varying crr)ss section in the longitudinal direction. Infiltration of Cu was performed at 115$0^{\circ}C$ for 1 hour under $H_2$. W-Cu composite with graded Cu composition of 14 to 27 wt％ was finally prepared. In this process the gradient of composition could be conveniently controlled by varying the gradient of cross sectional area of graphite mold, temperature and pressure.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4989-4994
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• 2014

Background: It has been reported that COX-2 expression is associated with MMP-2 expression in thyroid and breast cancers, suggesting that MMPs are linked to COX-2-mediated carcinogenesis. Several polymorphisms within the MMP2 promoter region have been reported in cases with oncogenesis and tumor progression, especially in colorectal carcinogenesis. Materials and Methods: This research evaluated risk of association of the SNPs, including genes for COX-2 (AIG transition at +202) and MMP-2 (Crr transition at-1306), with colorectal cancer in 125 patients and 125 healthy controls. Results and Conclusions: Our data confirmed that MMP2 C-1306 T mutations were significantly more common in colon cancer patients than in our control Saudi population; p=O.0121. On the other hand in our study, there was no significant association between genotype distribution ofthe COX2 polymorphism and colorectal cancer; p=0.847. An elevated frequency ofthe mutated genotype in the control group as compared to the patients subjects indeed suggested that this polymorphism could decrease risk in the Saudi population. Our study confirmed that the polymorphisms that could affect the expressions of MMP-2 and COX-2 the colon cancer patients were significantly higher than that in the COX-2 negative group. The frequency of individuals with MMP2 polymorphisms in colon cancer patients was higher than individuals with combination of COX2 and MMP2 polymorphisms. Our study confirmed that individuals who carried the polymorphisms that could affect the expressions ofCOX2 are more susceptible to colon cancer. MMP2 regulatory polymorphisms could be considered as protective; further studies need to confirm the results with more samples and healthy subjects.

• 한국의류산업학회지
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• 제13권3호
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• pp.346-352
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• 2011

The purpose of this study were to see what is the color preference for college students and the meaning of color, based on color psychology. The subjects are the male and female university students in Busan and the survey is conducted in March 2009, September 2009. Analysis is based on eight kinds of colors such as red, orange, yellow, green, cyan, blue, purple which are used in the psychological analysis of Howard & Dorothy Sun Corporate CRR (Colour reflection reading), and words representing the meaning of colors. A total of 259 questionnaires were used to analyze data and analysis was conducted by using SPSS 14.0 statistical package. First, by examining the best three colors among eight colors, the red which represents sociable and passionate leadership and a lot of energy was the first. Second, in terms of positive and negative sense, the green is stable, protected, red is passionate, strong', yellow is bright, happy and green is' clean, young. The Blues has peaceful, tranquil image', the orange is lively animation, cheerful, and the purple shows a positive meaning of beautiful, precious, often mature, loving. Third, the preferences of boys and girls to compare colors in the first preferred color, there were significant differences between boys and girls. Most boys prefer blue, while the girls like red the most. Both boys and girls look at the meaning of green color with the most positive sense and especially male students have the negative connotation about the green color than female students.

• Journal of Microbiology and Biotechnology
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• 제9권5호
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• pp.582-588
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• 1999

A Brevibacterium lactofermentum gene coding for a glucose-specific permease of the phosphoenolpyruvate-dependent phosphotransferase system (PTS) was cloned, by complementing an Escherichia coli mutation affecting a ptsG gene with the B. lactofermentum genomic library, and completely sequenced. The gene was identified as a ptsG, which enables an E. coli transformant to transport non-metabolizable glucose analogue 2-deoxyglucose (2DG). The ptsG gene of B. lactofermentum consists of an open reading frame of 2,025 nucleotides encoding a polypeptide of 674 amino acid residues and a TAA stop codon. The 3' flanking region contains two stem-loop structures which may be involved in transcriptional termination. The deduced amino acid sequence of the B. lactofermentum enzyme $II^{GIe}$ specific to glucose ($EII^{GIe}$) has a high homology with the Corynebacterium glutamicum enzyme $II^{Man}$ specific to glucose and mannose ($EII^{Man}$), and the Brevibacterium ammoniagenes enzyme $II^{GIc}$ specific to glucose ($EII^{GIc}$). The 171-amino-acid C-terminal sequence of the $EII^{Glc}$ is also similar to the Escherichia coli enzyme $IIA^{GIc}$ specific to glucose ($IIA^{GIc}$). It is interesting that the arrangement of the structural domains, IIBCA, of the B. lactofermentum $EII^{GIc}$ protein is identical to that of EIIs specific to sucrose or $\beta$-glucoside. Several in vivo complementation studies indicated that the B. lactofermentum $EII^{Glc}$ protein could replace both $EII^{ Glc}$ and $EIIA^{Glc}$ in an E. coli ptsG mutant or crr mutant, respectively.

• 대한임상검사과학회지
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• 제39권1호
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• pp.31-36
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• 2007

The purpose of the clinically reportable range (CRR) in clinical chemistry is to estimate linearity in working range. The reportable range includes all results that may be reliably reported, and embraces two types of ranges: the analytical measurement range (AMR) is the range of analyte values that a method can directly measure on the specimen without any dilution, concentration, or other pretreatment not part of the usual assay process. CAP and JCAHO require linearity on analyzers every six months. The clinically reportable range is the range of analyte values that a method can measure, allowing for specimen dilution, concentration, or other pretreatment used to extend the direct analytical measurement range. The AMR cannot exceed the manufacturer's limits. Establishing AMR is easily accomplished with Calibration Verification Assessment and experimental Linearity. For example: The manufacturer states that the limits of the AST on their instrument are 0-1100. The lowest level that could be verified is 2. The upper level is 1241. The verified AMR of the instrument is 2-1241. The lower limit of the range is 2, because that is the lowest level that could be verified by the laboratory. The laboratory could not use the manufacturer's lower limit of 2 because they have not proven that the instrument values below 2 are valid. The upper limit of the range is 1241, because although the lab has shown that the instrument is linear to 1241, the manufacturer does not make that claim. The laboratory needs to demonstrate the accuracy and precision of the analyzer, as well the validation of the patient AMR. Linearity requirements have been eliminated from the CLIA regulations and from the CAP inspection criteria, however, many inspectors continue to feel that linearity studies are a part of good lab practice and should be encouraged. If a lab chooses to continue linearity studies, these studies must fully comply with the calibration/calibration verification requirements of CLIA and/or CAP. The results of lower limit and upper limit of clinically reportable range were total protein (2.1 - 79.9), albumin (1.3 - 39), total bilirubin (0.2 - 106.2), alkaline phosphatase (13 - 6928.2), aspartate aminotransferase (24 - 7446), alanine aminotransferase (13 - 6724.2), gamma glutamyl transpeptidase (16.64 - 9904.2), creatine kinase (15.26 - 4723.8), lactate dehydrogenase (127.66 - 13231.8), creatinine (0.4 - 129.6), blood urea nitrogen (8.67 - 925.8), uric acid (1.6 - 151.2), total cholesterol (48.52 - 3162), triglycerides (36.91 - 3367.8), glucose (31 - 4218), amylase (21 - 6694.2), calcium (3.1 - 118.2), inorganic phosphorus (1.11 - 108), HDL (11.74 - 666), NA (58.3 - 1800), K (1.0 - 69.6), CL (38 - 1230).