• Journal of Microbiology and Biotechnology
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• 제22권8호
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• pp.1113-1117
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• 2012

Shigella sonnei is a causal agent of fever, nausea, stomach cramps, vomiting, and diarrheal disease. The present study describes a quantitative polymerase chain reaction (qPCR) assay for the specific detection of S. sonnei using a primer pair based on the methylase gene for the amplification of a 325 bp DNA fragment. The qPCR primer set for the accurate diagnosis of Shigella sonnei was developed from publically available genome sequences. This quantitative PCR-based method will potentially simplify and facilitate the diagnosis of this pathogen and guide disease management.

• 동아시아식생활학회지
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• 제5권1호
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• pp.101-107
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• 1995

Staphylococcus aureus, the most salt-tolerant food-borne pathogen, produces enterotoxins which may cause symptoms such as vomiting, diarrhea, nausea, and cramps. Since this bacterium has been able to grow at extremely high osmolarity its identity in foods with low water activity values such as salted or dried foods is of great concern. In this study, the growth of S. aureus at high osmolarity has been studied and the doubling time of S. aureus grown at TSB medium containing 15% NaCl has been found to be increased to 4∼5 hours. The stimulation of proline uptake after exposure of cells to high concentration of both extracellular KCl and sucrose was not increased. Stimulation of proline uptake at these environment only occured when 25mM NaCl was present I transport buffer. In additional experiments, the time required to reach mid-logarithmic phase in defined medium of high osmolarity found to be reduce by the presence of glycine betaine, proline, and choline.

• Annals of Clinical Neurophysiology
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• 제5권2호
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• pp.202-209
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• 2003

Postpolio syndrome (PPS) refers to a constellation of neuromuscular and orthopedic symptoms and signs that have been noted to occur in patients with remote antecedent poliomyelitis. It has been increasingly recognized that individuals recovering from acute poliomyelitis develop new symptoms, most commonly weakness, fatigue, and pain that develops decades after initial disease in the region previously affected. Associated symptoms may include dysphagia, respiratory insufficiency, new muscular atrophy, dysarthria, muscle cramps, fasciculations, sleep abnormalities, and cold intolerance. Although the concepts of PPS was first described in the late 1800s, it was not until nearly 100 years later that the concept of PPS was more widely recognized and defined. This was due largely to the polio epidemic of the 1940s and 1950s that left many survivors in the world. The virtual epidemic of PPS that occurred among these polio survivors in the 1980s and 1990s has served as a catalyst to attract medical attention to this syndrome.

• 대한정형외과스포츠의학회지
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• 제3권2호
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• pp.111-117
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• 2004

스포츠 활동 중 하퇴부 손상 및 동통은 과도한 훈련활동 및 강도 증가, 잘못된 훈련 방법, 훈련 환경의 적용 잘못으로 발생하는 경우가 많으며 주로 달리기, 축구, 롤러브레이드 등 하지를 많이 사용하는 종목에서 발생된다. 급성 손상으로는 급성 구획 증후군, 근육 손상 및 좌상, 근 경련 등이 있으며 만성 손상으로는 만성 활동성 구획 증후군, shin splints, 피로골절, 아킬레스 건염 등이 발생된다. 이러한 손상이 발생되는 원인과 치료 방법에 대해 알아보고 적절한 훈련 방법, 보조구 장착을 하여 하퇴부 손상을 예방할 수 있는 방법이 중요할 것으로 생각된다.

• Journal of Medicine and Life Science
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• 제17권3호
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• pp.98-102
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• 2020

Influenza is a common disease that causes epidemics yearly due to the influenza virus. If patients with influenza present with rare symptoms, the diagnosis may be delayed and the condition is difficult to treat. A 5-year-old boy presented to the emergency room with fever and cramps. Brain computed tomography showed low attenuation in the thalamus and brain stem, which was suggestive of encephalopathy caused by influenza virus. Another 5-year-old girl visited the emergency room with mild fever and painful calf edema. She was diagnosed with myositis caused by influenza and treated accordingly.

• Journal of Korean Neurosurgical Society
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• 제46권1호
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• pp.52-55
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• 2009

Writer's cramp is a type of idiopathic focal hand dystonia characterized by muscle cramps that accompany execution of the writing task specifically. There has been renewed interest in neurosurgical procedures for the treatment of dystonia over the past several years. In particular, deep brain stimulation (DBS) has received increasing attention as a therapeutic option for patients with dystonia. However, to date, limited reporters made investigations into DBS in relation to the Writer's cramp. In this case, unilateral Ventro-oralis complex (Vo) DBS resulted in a major improvement in patient's focal dystonic movement disorders. Her post-operative Burke-Fahn-Marsden Dystonia Rating (BFMDR) scale demonstrated 1 compared with pre-operative BFMDR scale 4. We conclude that thalamic Vo complex DBS maybe an important neurosurgical therapeutic option for Writer's cramp.

• 기본간호학회지
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• 제14권4호
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• pp.474-482
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• 2007

Purpose: This study was done to provide fundamental data for nursing interventions to prevent and reduce fatigue and to identify fatigue and kidney disease symptoms in female patients on hemodialysis and evaluate factors associated with this fatigue. Method: A cross-sectional study design was used with self-administered questionnaires which included general characteristics and the fatigue scale developed by Brown, Dittner, Findly, & Wessely(2005)(Cronbach's $\alpha=0.98$ and for present study $\alpha=0.96$) and a review of laboratory data. From eight dialysis units, 84 women were enrolled. Data were analyzed using the SAS program. Results: Mean score for fatigue was 49.4(range $16{\sim}78$) and fatigue by research variables was significantly different by age(0.046), employment status(0.041), menopause(0.009), hypoalbuminemia(0.022), length of time on dialysis(0.48) and kidney disease symptoms(0.000). Correlations between fatigue and lack of strength, dizziness, and cramps after dialysis were significantly higher. Factors affecting fatigue were kidney disease symptoms and length of time on dialysis, explaining 49.2% of fatigue. Conclusion: A comprehensive approach considering kidney disease symptoms, length of time on hemodialysis, age, menopause, and hypoalbuminemia are required for interventions to reduce fatigue in female patients on hemodialysis.

• 대한한방부인과학회지
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• 제21권1호
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• pp.134-149
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• 2008

Purpose: Dysmenorrhea is a common gynecologic condition among reproductive-age women. It consisted with menstrual clamps and other symptoms such as nausea. vomiting, diarrhea, and fatigue. Pain control for this disease mainly through NASIDs. but recently CAM therapies, acupuncture and others for painful menstruation are widely used in western countries. But RCT articles about dysmenorrhea in Korea, are not enough to lead such global research trends. The purpose of this study is to review treatment method and other research tendency about dysmenorrhea in Korean Medicine(KM) related dominant journals. Methods: Searching was done through web site and directly searched dysmenorrhea related articles in journals of Korean medicine Gynecology, published during 1996-2007. Results: Twenty five articles were searched in KM related journals, then two of them were simple case report and ten were paper of clinical trials. But there no RCT or control group-designed study. All of them present positive effect on dysmenorrhea but drop out rates were relatively high. Conclusion: KM therapies including acupuncture and herbal medicine have some beneficial effect to resolve menstrual cramps, but KM therapy related Korean articles don't have strong objective power as a evidence in the viewpoint of EBM. So continuous clinical trials such as RCT and multi center trials are needed.

• Journal of Yeungnam Medical Science
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• 제34권1호
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• pp.101-105
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• 2017

Gitelman syndrome is a condition caused by a mutation of the thiazide sensitive Na-Cl cotransporter gene on the distal convoluted tubule. It results in a variety of clinical features, including hypokalemia, hypomagnesemia, hypocalciuria, and metabolic alkalosis. It is often diagnosed in asymptomatic adults presented with unexplained hypokalemia; however, it is sometimes associated with muscular cramps, numbness, fatigue, weakness, or paralysis. We experienced a case of rheumatoid arthritis accompanied by Gitelman syndrome, presented with hand tremor. We diagnosed her using renal clearance study and genetic analysis. Here, we report our experiences regarding this case along with a literature review.

• 한국자기공명학회논문지
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• 제14권1호
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• pp.38-44
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• 2010

In liquids NMR, $^{1}H$ is the most widely observed nucleus, which is not the case in solids NMR. The reason is due to the strong homo-dipolar interactions between the hydrogen atoms which mask the useful chemical shift information. Therefore we must remove the strong homo-dipolar interactions in order to get structural information, which can be investigated by the isotropic chemical shift. There are two ways of obtaining it. One is the ultra-fast MAS of ca. 70 kHz spinning speed, which has become available only recently. The other way is devising a pulse sequence which can remove the strong homo-dipolar interaction. In the latter way, MAS with a moderate spinning rate of a few kHz, is enough to remove the chemical shift anisotropy. In this report, 1D-CRAMPS and 2D MASFSLG techniques are utilized and their results will be compared. This kind of highresolution $^{1}H$ NMR for solids, should become a valuable analytical tool in the understanding and the developing of a new class of hydrogen storage materials. Here ammonium borane $-NH_{3}BH_{3}$, whose hydrogen content is high, is used as a sample.