• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2001년도 봄 학술발표회 논문집
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• pp.175-182
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• 2001

The PMT test results are compared with other in situ test such as Standard Penetration Test (SPT), Cone Penetration Test (CPT), Field Vane Test (FVT) and the laboratory test in order to investigate the correlationships for the strength parameters obtained from Busan and Incheon areas. Many proposed correlation formulas also make a comparative study and new correlation formulas for domestic soils are introduced. Limit pressure ( $P_1$) could be determined by P-log($\Delta$V/V) and Relative volume Method. PMT for the granular soils showed relatively high correlation with SPT, while CPT has good correlation with PMT for cohesive soil. The predicted undrained shear test ( $S_{u}$) by the PMT test results for Incheon and Busan samples showed low correlativity with proposed equations, therefore, new correlation formulas are proposed for domestic soils.s.

• 대한한방체열의학회지
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• 제3권1호
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• pp.60-66
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• 2004

Purpose This study is to examine of Neurometer for the diagnosis of cold hypersensitivity Method Among patients who visited the oriental gynecological department in Kangnam Korean Hospital from October. 2000 to December. 2000, 37 women were diagnosed as cold hypersensitivity by D.I.T.I. We measured the limbs' temperature by D.I.T.I. and Current perception threshold(CPT) of median N., ulnar N., radial N., peroneal N., sural N., tibial N., saphenous N. by neurometer Patients were divided into mild and severe group depending on the temperature difference between proximalis and distalis in limbs Result and Conclusion 1. In severe group, CPT of median N., ulnar N., radial N. was higher on 250Hz and 200Hz. 2. In severe group, Mean CPT of peroneal N., sural N., tibial N., saphenous N. was higher on every Hz.

• 약학회지
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• 제53권4호
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• pp.228-234
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• 2009

Topoisomerase I (Topo I) participates in the DNA replication, transcription, and repair. Binding of Topo I inhibitor to the Topo I-DNA cleavage complex forms stabilized ternary complex which blocks DNA religation and ultimately causes cell death. Camptothecin (CPT) and its derivatives have been among the most effective anticancer drugs by inhibition of topo I. However, efforts to synthesize non-CPT drugs have been actively going on because the CPT derivatives have several limitations such as poor solubility, short half-life, and side effects. As an indenoisoquinoline, NSC314622 is not as potent as CPT, but its chemical stability and slower reversibility of the cleavage complex made it a good lead compound. Recently, a series of indenoisoquinoline analogues were synthesized with substituted dimethoxy or methylenedioxy on the aromatic ring and alkylamino on the lactam nitrogen. Some of them showed quite good Topo I inhibitory activity. Using the computer docking program, Surflex-Dock, indenoisoquinoline analogues were docked into the human Topo I-DNA cleavable complex. The docking results showed that the compounds with activity better than NSC314622 intercalated between the -1 and +1 base pairs at the cleavage site, but those with little or no activities did not appear to intercalate. These results could be useful to design new Topo I inhibitors improved than CPT.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회B
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• pp.3050-3055
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• 2007

A wind turbine is one of the most popular energy conversion systems to generate electricity from the natural renewable energy source and an axial-flow type wind turbine is the most popular system for the electricity generation in the wind farm nowadays. In this study, a cross-flow type turbine has been studied for the application of wind turbine for electricity generation. The target capacity of electric power generation of the model wind turbine developing on the project is 12 volts, 130A/H (about 1.56kW). The important design parameters of the model turbine impeller are the inlet and exit angle of the turbine blade, number of blade, hub/tip ratio and the exit flow angle of the casing. In this study, the radial equilibrium theorem was used to decide the inlet and exit angle of the impller blade and CFD technique was used to have the performance analysis of the designed model power turbine to find out the optimum geometry of the CPT impeller and casing. The designed CPT with 24 impeller blades at ${\alpha}=82^{\circ}$, ${\beta}=40^{\circ}$ of turbine blade angle was estimated to generate 284.6 N.m of indicated torque and 2.14kW of indicated power.

• Journal of Power Electronics
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• 제16권5호
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• pp.1678-1688
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• 2016

This paper presents a capacitive power transfer (CPT) system using a Class-E resonant inverter. A Class-E resonant inverter is chosen because of its ability to perform DC-to-AC inversion efficiently while significantly reducing switching losses. The proposed CPT system consists of an efficient Class-E resonant inverter and capacitive coupling formed by two flat rectangular transmitter and receiver plates. To understand CPT behavior, we study the effects of various coupling distances on output power performance. The proposed design is verified through lab experiments with a nominal operating frequency of 1 MHz and 0.25 mm coupling gap. An efficiency of 96.3% is achieved. A simple frequency tracking unit is also proposed to tune the operating frequency in response to changes in the coupling gap. With this resonant frequency tracking unit, the efficiency of the proposed CPT system can be maintained within 96.3%-91% for the coupling gap range of 0.25-2 mm.

• 대한금속재료학회지
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• 제47권10호
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• pp.635-643
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• 2009

The resistance to pitting corrosion of Fe-Cr alloys was evaluated by performing potentiodynamic polarization and critical pitting temperature (CPT) tests. For the potentiodynamic polarization tests, various standards were applied, i.e., KS D 0238 (wet, dry), ASTM G 61, and ISO 17475, showing different potentiodynamic polarization results including pitting potentials. ASTM G 61 and ISO 17475 standards presented relatively higher pitting potential while KS D 0238 (dry) indicated lower values than the others. Effects of surface roughness, scan rates, and exposure time to air before tests were also investigated. CPT tests were performed under two different applied potentials, 300 m$V_{SCE}$ and 200 m$V_{SCE}$ in deaerated 1 M NaCl aqueous solution. CPT values and the polarization test results showed a linear relationship.

• 한국지반신소재학회논문집
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• 제5권4호
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• pp.1-10
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• 2006

본 논문에서는 부산신항 민자부두 북컨테이너 1-1단계 조성부지에 시공된 PBD공법의 지반개량효과를 검증하기 위하여 침하량과 압밀침하에 따른 비배수 전단강도를 비교하였다. 적용된 PBD 설계이론을 제시하였으며 CPT 시험결과와 현장 계측결과를 비교함으로써 PBD공법의 개량효과를 검토하였다. 본 사례를 통하여 향후 수행될 각종 연약지반 개량공사에 PBD 공법이 적용될 때 공법의 효용성 및 설계 해석기법의 적용성 검토에 유용한 자료가 되길 기대한다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권7호
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• pp.3335-3341
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• 2014

Background: Severe toxicity is commonly observed in cancer patients receiving irinotecan (CPT-11) UDPglucuronosyltransferase1A1 (UGT1A1) catalyzes the glucuronidation of the active metabolite SN-38 but the relationship between UGT1A1 and severe toxicity remains unclear. Our study aimed to assess this point to guide clinical use of CPT-11. Materials and Methods: 89 cancer patients with advanced disease received CPT-11-based chemotherapy for at least two cycles. Toxicity, including GI and hematologic toxicity was recorded in detail and UGT1A1 variants were genotyped. Regression analysis was used to analyse relationships between these variables and tumor response. Results: The prevalence of grade III-IV diarrhea was 10.1%, this being more common in patients with the TA 6/7 genotype (5 of 22 patients, 22.7%) (p<0.05). The prevalence of grade III-IV neutropenia was 13.4%and also highest in patients with the TA 6/7 genotype (4 of 22 patients; 18.2%) but without significance (p>0.05). The retreatment total bilirubin levels were significantly higher in TA6/7 patients (mean, $12.75{\mu}mol/L$) with compared to TA6/6 (mean, $9.92{\mu}mol/L$) with p<0.05. Conclusions: Our study support the conclusion that patients with a $UGT1A1^*28$ allele (s) will suffer an increased risk of severe irinotecan-induced diarrhea, whether with mid-or low-dosage. However, the $UGT1A1^*28$ allele (s) did not increase severe neutropenia. Higher serum total bilirubin is an indication that patients UGT1A1 genotype is not wild-type, with significance for clinic usage of CPT-11.

• 한국통신학회논문지
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• 제21권1호
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• pp.47-58
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• 1996

An object color can be seen differently under the various outer illuminants. However, human visual system has color constnacy that the object color can be seen constantly under the different outer illuminants. When the viewer watches TV under specific that the object color can be seen constantly under the different outer illuminants. When the viewer bathes TV under specific outer illuminants, he perceives distortes color due to the emitting specturm of outer illuminants as well as the radiation of CPT itself. Namely, when the outer illuminants such as fluorescent and incandescent lamps incident on CPT, brightness, saturation, hue, itself. Namely, when the outer iluminants such as fluorescent and incandescent lamps incident on CPT, brightness, saturation, hue, and contrast on color pictures are changend, he perceives distortedcolr fromthe original color. In this paper color enhancement algorithm based on light intensity and outer light decision funtion using RGB sensor was proposed. The implemented TV of proposed algorithm has higher visual quality at the view point of human visual system and more vivid than that ofcoventional color TV.

• Geomechanics and Engineering
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• 제1권1호
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• pp.17-34
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• 2009

There has been growing agreement that geotechnical reliability-based design (RBD) is necessary for establishing more advanced and integrated design system. In this study, resistance factors for LRFD pile design using CPT results were investigated for axially loaded driven piles. In order to address variability in design methodology, different CPT-based methods and load-settlement criteria, popular in practice, were selected and used for evaluation of resistance factors. A total of 32 data sets from 13 test sites were collected from the literature. In order to maintain the statistical consistency of the data sets, the characteristic pile load capacity was introduced in reliability analysis and evaluation of resistance factors. It was found that values of resistance factors considerably differ for different design methods, load-settlement criteria, and load capacity components. For the total resistance, resistance factors for LCPC method were higher than others, while those for Aoki-Velloso's and Philipponnat's methods were in similar ranges. In respect to load-settlement criteria, 0.1B and Chin's criteria produced higher resistance factors than DeBeer's and Davisson's criteria. Resistance factors for the base and shaft resistances were also presented and analyzed.