• Annals of Clinical Neurophysiology
• /
• v.19 no.2
• /
• pp.125-130
• /
• 2017

Background: Routine nerve conduction study (NCS) can only be used to evaluate the function of large fibers, and the results of NCS are often normal in patients with distal sensory polyneuropathy. The measurement of the current perception threshold (CPT) has been reported to represent a variety of peripheral nerve fiber functions. This study was performed to investigate the value of measuring CPT in patients with diabetic sensory polyneuropathy who have no abnormalities in routine NCS. Methods: Twenty-seven diabetic patients with sensory polyneuropathy and normal routine NCS and 18 age-matched control subjects participated in this study. The CPT was measured on the unilateral index finger and great toe of each subject at frequencies of 5 Hz, 250 Hz, and 2,000 Hz. Results: CPT values were significantly higher in the patient group than in the control group, especially with stimuli at the lowest frequency of 5 Hz (p < 0.05). There were significant correlations between the CPT values obtained at three different frequencies in the patient group, whereas the correlation was only significant in the pair of 250 Hz/5 Hz (both in the hands and feet), and in the pair of 2,000 Hz/250 Hz (in the feet) for the control group. Conclusions: Our data suggest that the CPT test, especially at a stimuli frequency of 5 Hz, may be a useful screening tool for diabetic polyneuropathy in patients who show no abnormalities in routine NCS.

• Korean Journal of Cleft Lip And Palate
• /
• v.4 no.1
• /
• pp.39-43
• /
• 2001

The design of osteotomy plane in orthognathic surgery has been developed to diminish the nerve injury. Intraoral Vertico-Sagittal Ramus Osteotomy (IVSRO) is the one of the best way to minimize untoward results, which is designed not to expose the lingula. We evaluated the nerve damage before and after with current perception threshold (CPT) test which is modem and numerically expressible way of nerve damages. Sixty patients underwent IVSRO since 1998 were evaluated. They were divided into 2 groups; one group underwent IVSRO only, and the other underwent IVSRO plus genioplasty. The both groups were evaluated with CPT test 1 week before surgery, and 1, 3 and 6 months after surgery. The CPT test was performed on A-beta, A-delta and C fiber respectively. 111e result showed that the recovery of sensory function of damaged nerve fibers was observed at the period of three to six months after surgery. There was no impairment of nerve function after only the IVSRO . But there were sensory disturbances in cases of additional genioplasty group. We thought that one of major factors on nerve damages were exposure of nerve and traction injury during genioplasty.

• Journal of the Korean Geotechnical Society
• /
• v.20 no.8
• /
• pp.5-14
• /
• 2004

The settlement of foundations under working load conditions is an important design consideration. Well-designed foundations induce stress-strain states in the soil that are neither in the linear elastic range nor in the range usually associated with perfect plasticity. Thus, in order to accurately predict working settlements, analyses that are more realistic than simple elastic analyses are required. The settlements of footings in sand are often estimated based on the results of in-situ tests, particularly the standard penetration test (SPT) and the cone penetration test (CPT). In this paper, we analyze the load-settlement response of vertically loaded footings placed in sands using both the finite element method with a non-linear stress-strain model and the conventional elastic approach. Based on these analyses, we propose a procedure for the estimation of footing settlement in sands based on CPT results.

• The Journal of Pediatrics of Korean Medicine
• /
• v.20 no.1
• /
• pp.109-135
• /
• 2006

Objective : In the present study, the author tried to investigate whether six oriental medical prescriptions named gamisingitang (SGT), gamijungtang (IJT), gamicheongpyetang (CPT), galhwengchihyosan (CHS), chwiyeontong (CYT), sigyoungcheongpyetang (SCPT) significantly affect mucin release from cultured hamster tracheal surface epithelial (HTSE) cells. Methode : Confluent HTSE cells were inetabolically radiolabeled with $^{3}H-glucosamine$ for 24 hrs and chased for 30 min in the presence of drugs aforementioned, respectively, to assess the effect of each drug on $^{3}H-mucin$ release. Possible cytotoxicities of effective drugs were assessed by measuring lactate dehydrogenase(LDH) release. Additionally, total elution profiles of control spent media and treatment sample (CPT, CHS, SCPT and CYT) through Sepharose CL-4B column were analysed and effect of CPT, CHS and CYT on MUC5AC mRNA expression in cultured HTSE cells were invsetigated. Results : (1) SGT and IJT did not affect mucin release without cytotoxicity; (2) CPT, SCPT and CHS significantly stimulated mucin release from cultured HTSE cells, with significant cytotoxicity; (4) CPT, CHS, SCPT and CYT chiefly affected the 'mucin' release and did not affect significantly the release of the releasable glycoproteins with less molecular weight than mucin. This result suggests that the four herbal prescriptions specifically affect the release of mucin ; (5) CTP and CHS did not significantly affect the expression levels of MUC 5AC mRNA, however, CYT significantly inhibit the expression levels of MUC 5AC mRNA. Conclusion : CYT can decrease the synthesis of mucin at gene level in cultured HTSE cells.

• Journal of the Korean Geotechnical Society
• /
• v.21 no.10
• /
• pp.113-122
• /
• 2005

Application of Limit State Design in geotechnical engineering has become world-widely popular. While LRFD code in the North America presents geotechnical load and resistance factors, the values of resistance factors proposed by these methods are still unstable with limited application. CPT has been widely used for the pile design and various methods have been proposed to estimate the bearing capacity of piles. In this paper, resistance factors for representative pile design methods based on CPT results are evaluated. Field pile load test and CPT results were collected and analyzed in order to obtain necessary statistical data and resistance factors. Resistance factors of the base, shaft, and total capacity are estimated. From fisrt order second moment (FOSM) analysis, resistance factors of $0.30{\sim}0.55$ are estimated for total load capacity.

• Diabetes and Metabolism Journal
• /
• v.42 no.6
• /
• pp.519-528
• /
• 2018

Background: Clinical manifestations of diabetic peripheral neuropathy (DPN) vary along the course of nerve damage. Nerve conduction studies (NCS) have been suggested as a way to confirm diagnoses of DPN, but the results have limited utility for evaluating clinical phenotypes. The current perception threshold (CPT) is a complementary method for diagnosing DPN and assessing DPN symptoms. We compared NCS variables according to clinical phenotypes determined by CPT measurements. Methods: We retrospectively enrolled patients with type 2 diabetes mellitus who underwent both NCS and CPT tests using a neurometer. CPT grades were used to determine the clinical phenotypes of DPN: normoesthesia (0 to 1.66), hyperesthesia (1.67 to 6.62), and hypoesthesia/anesthesia (6.63 to 12.0). The Michigan Neuropathy Screening Instrument (MNSI) was used to determine a subjective symptom score. DPN was diagnosed based on both patient symptoms (MNSI score ${\geq}3$) and abnormal NCS results. Results: A total of 202 patients (117 men and 85 women) were included in the final analysis. The average age was 62.6 years, and 71 patients (35.1%) were diagnosed with DPN. The CPT variables correlated with MNSI scores and NCS variables in patients with diabetes. Linear regression analyses indicated that hypoesthesia was associated with significantly lower summed velocities and sural amplitudes and velocities, and higher summed latencies, than normoesthesia. Sural amplitude was significantly lower in patients with hyperesthesia than in patients with normoesthesia. Conclusion: NCS variables differed among patients with diabetes according to clinical phenotypes based on CPT and decreased sural nerve velocities was associated with hyperesthesia.

• Journal of the Korean Geotechnical Society
• /
• v.25 no.2
• /
• pp.37-44
• /
• 2009

In this study, estimation methodology for the pile of ultimation lateral resistance, pu, and ultimate lateral capacity, Pu, is based on the CPT cone resistance $q_c$. Preexistent methodologies for ultimate lateral resistance and ultimate lateral capacity have been generally represented with relative density, vertical effective stresses, and various $K_0$ values which are important for analyzing sandy soil. These methodologies, however, did not consider the horizontal effective stress and the effects of construction site conditions. Therefore, CPT-based methodology for the estimation of the ultimate lateral pile load capacity Hu was proposed. Calibration chamber test results were analyzed and compared with calculated results. The proposed estimation methodology for the pile of $p_u$ can be effectively utilized as alternative to preexistent methods.

• Geomechanics and Engineering
• /
• v.31 no.1
• /
• pp.113-127
• /
• 2022

The undrained shear strength of soil is considered one of the engineering parameters of utmost significance in geotechnical design methods. In-situ experiments like cone penetration tests (CPT) have been used in the last several years to estimate the undrained shear strength depending on the characteristics of the soil. Nevertheless, the majority of these techniques rely on correlation presumptions, which may lead to uneven accuracy. This research's general aim is to extend a new united soft computing model, which is a combination of random forest (RF) with grasshopper optimization algorithm (GOA) to the pile set-up parameters' better approximation from CPT, based on two different types of data as inputs. Data type 1 contains pile parameters, and data type 2 consists of soil properties. The contribution of this article is that hybrid GOA - RF for the first time, was suggested to forecast the pile set-up parameter from CPT. In order to do this, CPT data and related bore log data were gathered from 70 various locations across Louisiana. With an R² greater than 0.9098, which denotes the permissible relationship between measured and anticipated values, the results demonstrated that both models perform well in forecasting the set-up parameter. It is comprehensible that, in the training and testing step, the model with data type 2 has finer capability than the model using data type 1, with R² and RMSE are 0.9272 and 0.0305 for the training step and 0.9182 and 0.0415 for the testing step. All in all, the models' results depict that the A parameter could be forecasted with adequate precision from the CPT data with the usage of hybrid GOA - RF models. However, the RF model with soil features as input parameters results in a finer commentary of pile set-up parameters.

• Journal of Korea Port Economic Association
• /
• v.29 no.1
• /
• pp.123-141
• /
• 2013

The purpose of this paper is to suggest a plan on promoting use of multimodal transport logistics terms in Incoterms, 2010. This study deals with the terms of three promotion factors which are a user's subjective factors, a trade transport logistics environment factors, and a term content factors. According to analysis results of the factors, a user's subjective factors(3.87 score) are scored the most ones of promotion factors of using multimodal transport logistics terms in Incoterms, 2010, to be compared with a trade transport logistics environment factors(3.60 score). with a term content factors(3.74 score). Therefore, first of all, it is important to promoting use of multimodal transport logistics terms in Incoterms, 2010 through as follows, a user's subjective factors : (1) to understand correlation of door to door multimodal transport and terms of Incoterms, 2010, (2) to promote use of multimodal transport logistics terms in Incoterms, 2010 in door to door multimodal transport, (3) to restrain customary use of FOB, CFR, CIF terms. And, the next, we have to promote use of multimodal transport logistics terms in Incoterms, 2010 through considering a trade transport logistics environment factors and a term content factors.

• Korean Journal of Food Science and Technology
• /
• v.48 no.5
• /
• pp.486-491
• /
• 2016

Efficacy of dielectric barrier discharge-cold plasma treatment (DBD-CPT) for microbial decontamination of onion powder was evaluated. Onion powder, inoculated with Escherichia coli O157:H7, Salmonella Enteritidis, or Listeria monocytogenes, was treated with helium DBD-CPT. DBD-CPT (9 kV, 20 min) inhibited E. coli O157:H7, S. Enteritidis, and L. monocytogenes by $1.4{\pm}0.5$, $2.3{\pm}0.3$, and $1.2{\pm}0.0log\;CFU/cm^2$, respectively. The inactivation levels of E. coli O157:H7, S. Enteritidis and L. monocytogenes increased by $2.2{\pm}0.1$, $2.5{\pm}0.1$ and $1.9{\pm}0.3log\;CFU/cm^2$, respectively, as water activity increased from 0.4 to 0.8, and increased by $2.3{\pm}0.4$, $2.1{\pm}0.1$ and $1.6{\pm}0.1log\;CFU/cm^2$, respectively, as the particle size increased from 0.3 to $1.0cm^2$. Neither the ascorbic acid and quercetin concentrations nor the color of onion powder was changed by DBD-CPT (p>0.05). These results demonstrate the potential for application of DBD-CPT in improving microbiological safety of onion powder while preserving the physicochemical properties.