• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.30 no.2
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• pp.77-81
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• 2019

Dysphagia may result from dysfunction of any of the components involved in the complex neuromuscular interaction of swallowing. Hyperfunction of any of the muscles involved in swallowing is a frequent cause of dysphagia. The cricopharyngeus muscle (CPM) is a key component of the upper esophageal sphincter. Cricopharyngeus muscle dysfunction (CPD) refers to the muscle's failure to appropriately and completely relax or expand during deglutition. A variety of disease processes may cause CPD and accurate diagnosis is paramount for appropriate treatment. In appropriately selected patients, intervention at the CPM may yield significant improvement in dysphagia. Interventions include nonsurgical, pharyngoesophageal segment dilatation, botulinum toxin (BoNT) injection, and criccopharyngeal myotomy. Injections of BoNT in patients with CPD have been reported to result in marked relief of dysphagia. Different techniques for instilling BoNT into the CPM have been described. Awake, in-office CPM BoNT injection with electromyography and/or fluoroscopic or ultrasound guidance is performed transcervically or via flexible endoscopy. Operative CPM BoNT injection involves rigid laryngoscopy and esophagoscopy with direct visualization of the CPM. BoNT should be prepared in low-volume, high-concentration dilutions to minimize the potential for undesired diffusion of the toxin. The effects of BoNT occur within weeks of injection and typically last up to 5 or 6 months.

• Journal of Biomedical Engineering Research
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• v.21 no.6
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• pp.543-549
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• 2000

위전도(Electrogastrography, EGG)는 복부에 전극을 부착하여 위에서 발생하는 위 근육의 전기적인 활동성(gastric electrical activity)을 측정하는 방법으로, 비관혈적이며 다른 검사에 비해 측정비용이 적게 든다. 그러나 위전도 신호는 주파수가 매우 낮으며(0.2~10cpm) 진폭이 매우 작기(10~100 $\mu$V) 때문에 측정에 어려움이 있으며, 분석이 어려워 아직까지 위전도 신호해석에 대한 이론이 정립되어 있지않다. 본 연구에서는 running spectrum 분석을 이용한 4채널 위전도 시스템을 개발하여 위에서 발생하는 활동전위를 측정하였다. 본 연구에서 개발한 4채널 위전도 시스템의 4개 채널 중 가장 3 cpm 백분율이 높은 베스트 채널과, 상용화된 1채널 시스템인 Digitrapper EGG와 같은 전극부착 위치인 채널 1의 3 cpm 백분율을 비교하였다. 베스트 채널과 채널 1의 식전 평균 3 cpm 백분율은 각각 89.5%와 83.2%이었으며 통계적으로 유의하였다(p〈0.001). 식후에는 평균 3 cpm 백분율이 각각 90.4%와 76.5%이었으며 통계적으로 유의하였다(p〈0.001). 결론적으로 1채널위전도 측정기로서는 각 개인의 다양한 위의 위치를 커버할 수 없으며 그에 따른 오진을 초래할 수도 있으므로 1채널 위전도 측정기보다 4채널 위전도 측정기가 더 우수하다는 것을 확인하였다.

• Journal of Pharmaceutical Investigation
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• v.23 no.3
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• pp.155-163
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• 1993

Inclusion complexation of 1,7,21,27-tetraaza[7.1.7.1]paracyclophane (CPM 55) with 2,7-dihydroxynaphthalene (2,7-DHN) or 1,3-dihydroxynaphthalene (1,3-DHN) in pD 1.17 $DCl-D_2O$ solution was investigated by $^1H$ nuclear magnetic resonance spectroscopy (NMR) using 4,4'-dimethylaminodiphenylmethane (ACM 11) as an acyclic analog of CPM 55. In CPM 55-naphthalene derivative complex, alkyl protons located in the cavity of CPM 55 were shown to be subjected to anisotropic shielding and protons of naphthalene moiety shifted remarkably to upfield. However, in ACM 11-naphthalene derivative systems, chemical shifts for protons of both DHN compounds were not significant. The remarkable chemical shift changes suggested that the naphthalene moiety of 2,7-DHN or 1,3-DHN was included in the hydrophobic cavity of CPM 55 in aqueous solution. From the continuous variation plots of induced chemical shifts of 2,7-DHN, it was found that 2,7-DHN was included in the cavity of CPM 55 at 1:1 molar stoichiometry. Both computer simulation of a inclusion complex and strong upfield chemical shift changes of 2,7-DHN protons supported the conformation of pseudoaxial inclusion as the presumed geometry of the host-guest complex.

• Journal of Korean Society for Atmospheric Environment
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• v.33 no.4
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• pp.319-325
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• 2017

In this study, the new particulate matter emissions considering condensable PM (CPM) of stationary pollutant sources were calculated to modify the CAPSS emissions based on only filterable PMs in Seoul and Incheon. When the new calculated emissions were compared to the existing filterable PM based emissions of local governments, different contribution patterns of emission sources were found. For example, the proportion of mobile sources was high when the filterable PM was considered; however, the contribution of non-industrial sources was dominant in Seoul when the emissions of CPM were considered. Also, the proportion of energy industrial combustion and manufacturing combustion sources was significant in Incheon when CPM emissions considered. Therefore, it seems to be much desirable to consider CPM emissions for determining adequate locations of collective energy facilities and manufacturing combustion facilities in the future. In addition, CPM should be considered to solve the dust problem nationwide. The emission analysis, diagnosis, prediction and countermeasures using CPM emissions should be appropriately performed.

• Korean Journal of Construction Engineering and Management
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• v.5 no.5 s.21
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• pp.84-92
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• 2004

Construction work varies with the project types. However, the success of all project types depends upon three conditions i.e. schedule, quality and cost. If these three conditions are fulfilled, then project said to be successful. In this paper, scheduling of a construction Project has been dealt with the application of CCPM method. CCPM has been introduced as a new theory in construction industry in 1997 at the United States, but its application is still insufficient in domestic field due to the absence of systematic study, A simulation has been conducted in a Bridge construction project to validate the possibility of CCPM in order to complement PERT/CPM in construction field. The result of study shows that the CCPM could be effective to reduce the project time duration than existing PERT/CPM technique.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.174.1-174.1
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• 2012

현재 인공위성 개발 프로젝트들을 계획하고 일정계획을 수립하기위해 간트차트가 널리 활용되고 있다. 간트차트는 프로젝트의 각 작업들이 언제 시작하고 종료되는지에 대한 작업 일정을 막대 도표를 이용하여 표시하는 프로젝트 일정표로 다양한 형태로 변경하여 사용할 수 있으나 작업경로를 표시할 수 없으며 계획의 변화에 대한 적응성이 약한 단점이 있다. 또한 일목요연하게 눈으로 보여줄 수 있으나 효과적인 프로젝트 관리에 중요한 활동 사이의 어떤 관계에 대한 정보를 주지 못한다. 인공위성개발과 같은 복잡한 프로젝트에 대해 간트차트와 더불어 PERT(Program evaluation and review technique)와 CPM(critical path method)과 같은 네트워크 도(Network Diagram)와 함께 사용될 수 있도록 그 이론과 활용방안에 대해 기술하고자 한다. PERT와 CPM은 큰 프로젝트를 계획하고 조정하기 위해 폭넓게 사용되는 두 가지 기법이다. PERT와 CPM을 사용하면 프로젝트 활동에 대한 그래프를 통한 도시, 프로젝트 소요시간 추정, 프로젝트 완료시간 준수를 위해 중요한 활동의 식별, 전체 프로젝트에 대한 지연 없이 가능한 각 활동의 지연시간 추정과 같은 이점이 있다. PERT와 CPM은 독립적으로 개발되었지만, 많은 공통점이 있다. 더 나아가서 둘 사이에 원래 존재했던 차이점은 많은 부분은 서로의 특징을 도입하면서 거의 사라졌다. 실제적으로 볼 때, 두 기법은 지금 같은 기법이며, 기술된 특징과 절차는 PERT분석 뿐 아니라 CPM 분석에도 적용될 수 있을 것이다.

• The Plant Pathology Journal
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• v.38 no.4
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• pp.296-303
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• 2022

The cucurbit powdery mildew (CPM) caused by different fungal species is a major concern for cucurbit crops around the world. In Argentina CPM constitutes the most common and damaging disease for cucurbits, especially for squash crops (Cucurbita moschata). The present study displays initial insights into the knowledge of the disease in western Argentina, including the determination of the prevalent species causing CPM, as well as the evaluation of the resistance of squash cultivars and breeding lines. Fungal colonies were isolated from samples collected in Mendoza province, Argentina. A field trial was also performed to assess the resistance of five squash accessions, including commercial cultivars and breeding lines. The severity of CPM was analyzed and epidemiological models were built based on empirical data. The morphological determinations and analysis with specific molecular markers confirmed Podosphaera xanthi as the prevalent causal agent of CPM in Mendoza. The results od the field trial showed differences in the resistance trait among the squash accessions. The advanced breeding line BL717/1 showed promising results as source of CPM resistance for the future development of open pollinated resistant cultivars, a crucial tool for an integrative control of the disease.

• Journal of Korean Society for Atmospheric Environment
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• v.32 no.5
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• pp.501-512
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• 2016

The study evaluated methods to measure condensable fine particles in flue gases and measured particulate matter by fuel and material to get precise concentrations and quantities. As a result of the method evaluation, it is required to improve test methods for measuring Condensable Particulate Matter (CPM) emitted after the conventional Filterable Particulate Matter (FPM) measurement process. Relative Standard Deviation (RSD) based on the evaluated analysis process showed that RSD percentages of FPM and CPM were around 27.0~139.5%. As errors in the process of CPM measurement and analysis can be caused while separating and dehydrating organic and inorganic materials from condensed liquid samples, transporting samples, and titrating ammonium hydroxide in the sample, it is required to comply with the exact test procedures. As for characteristics of FPM and CPM concentrations, CPM had about 1.6~63 times higher concentrations than FPM, and CPM caused huge increase in PM mass concentrations. Also, emission concentrations and quantities varied according to the characteristics of each fuel, the size of emitting facilities, operational conditions of emitters, etc. PM in the flue gases mostly consisted of CPM (61~99%), and the result of organic/inorganic component analysis revealed that organic dusts accounted for 30~88%. High-efficiency prevention facilities also had high concentrations of CPM due to large amounts of $NO_x$, and the more fuels, the more inorganic dusts. As a result of comparison between emission coefficients by fuel and the EPA AP-42, FPM had lower result values compared to that in the US materials, and CPM had higher values than FPM. For the emission coefficients of the total PM (FPM+CPM) by industry, that of thermal power stations (bituminous coal) was 71.64 g/ton, and cement manufacturing facility (blended fuels) 18.90 g/ton. In order to estimate emission quantities and coefficients proper to the circumstances of air pollutant-emitting facilities in Korea, measurement data need to be calculated in stages by facility condition according to the CPM measurement method in the study. About 80% of PM in flue gases are CPM, and a half of which are organic dusts that are mostly unknown yet. For effective management and control of PM in flue gases, it is necessary to identify the current conditions through quantitative and qualitative analysis of harmful organic substances, and have more interest in and conduct studies on unknown materials' measurements and behaviors.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.12
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• pp.2963-2967
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• 2015

The pump-probe scheme is used to analyze the cross-phase modulation penalty of a single-mode fiber in a WDM system. The pump signal is assumed to be a periodically modulated input like a raised sinusoidal. The periodic signal models an alternating bit sequence, and leads to an analytical expression of CPM penalty which is measured by EOP. The derived expression shows good agreement with numerical results in conventional single-mode fiber systems over a wide range of channel spacing, ${\Delta}f$. In dispersion-shifted fiber systems when ${\Delta}f$ < 100GHz, the derived expression shows increased discrepancy with the numerical results due to the increased FWM. This is not a surprising because the pump-probe scheme is used to analyze system performance degradation due to CPM.

• Journal of the military operations research society of Korea
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• v.1 no.1
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• pp.53-61
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• 1975