• Journal of Yeungnam Medical Science
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• 제39권3호
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• pp.216-222
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• 2022

Background: This study assessed the psychological impact of the outbreak of coronavirus disease 2019 (COVID-19) on university hospital nurses. It provides an assessment of mental health issues, including depression, anxiety, distress, and burnout of nurses dealing directly and indirectly with COVID-19. Methods: In a web-based, cross-sectional study, 111 nurses from Daegu Catholic University Hospital in Korea were enrolled from August 4 to August 9, 2020. Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Impact of Event Scale-Revised, and Maslach Burnout Inventory were used to assess the psychological symptoms of depression, anxiety, psychological distress, and burnout among the study participants. Results: Of 111 nurses, 35 (31.5%), nine (8.1%), 26 (23.4%), and 49 (44.1%) experienced depression, anxiety, distress, and burnout, respectively. Nurses who performed COVID-19-related tasks were more likely to have moderate depression (related vs. unrelated, 52.0% vs. 25.6%; p=0.037). There were no differences in anxiety, distress, and burnout between nurses with and without COVID-19-related tasks. More than 50% of the participants showed receptive and positive attitudes toward caring for COVID-19 patients. Conclusion: Nurses who performed COVID-19-related tasks had a higher risk of depression. There were no significant differences in anxiety, distress, and burnout between the two groups. Since nurses who perform COVID-19-related tasks are more prone to psychological distress, continued psychiatric interventions are required for infectious disease outbreaks with a high mortality rate for healthcare workers who are emotionally vulnerable.

• Journal of Chest Surgery
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• 제55권4호
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• pp.357-360
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• 2022

Patients with severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) may exhibit pulmonary fibrosis after the viral illness resolves. Some of these patients may experience severe functional lung impairment, and thus require transplants to prevent death or maintain a tolerable quality of life. Considering the reversibility of COVID-19 ARDS, lung transplant candidates are observed for 1-2 months and must be selected very carefully before transplantation. As the short-term outcomes of such patients are comparable to those of patients with other indications for transplantation, lung transplantation should be actively considered.

• 한국보건간호학회지
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• 제36권3호
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• pp.334-346
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• 2022

Purpose: This survey was conducted to investigate the level of coronavirus disease 2019 (COVID-19)-related peritraumatic distress and job stress among clinical nurses and evaluate their effects on nursing performance. Methods: The participants were 115 nurses from 5 hospitals in 3 regions in Korea. The peritraumatic distress index (PDI), job stress, and nursing performance scales were used for the analysis. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, and multivariate regression analysis. Results: The level of peritraumatic distress of nurses was scored at 22.8 ± 9.26 (range 0 to 45). The level of job stress was scored at 2.69 ± 0.51 (range 1.3 to 3.7). The level of nursing performance was scored at 3.73 ± 0.51(range 1.76 to 5.0). Peritraumatic distress was observed to be positively correlated with job stress (r=.408, p<.001). However, peritraumatic distress and job stress were not correlated with nursing performance. In multivariate regression, the only variable seen to affect nursing performance was the work experience of the nurses. Work experience levels of five to fifteen years were observed to have a significant positive effect on nursing performance. Conclusion: The work experience of nurses directly influenced nursing performance during the pandemic period. Thus, to retain more nurses and to improve nursing performance, it would be necessary to develop various strategies to decrease their peritraumatic distress and job stress caused by the pandemic.

• 대한간호학회지
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• 제53권3호
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• pp.309-323
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• 2023

Purpose: This study aimed to develop and test a model for posttraumatic growth among cured patients with COVID-19. This model was based on Calhoun and Tedeschi's Posttraumatic Growth model and a literature review. Methods: The participants comprised 223 patients cured from COVID-19 who were ≥ 19 years of age. The data were collected through an online questionnaire from March 21 to 24, 2022. The assessment tools included the Impact of Event Scale: Revised Korean version, the Connor-Davidson Resilience Scale, the Distress Disclosure Index, the Multidimensional Scale of Perceived Social Support, the Korean version of the Event-related Rumination Inventory, and the Korean version of the Post-traumatic Growth Inventory. Data were analyzed using the IBM SPSS version 24.0 and IBM AMOS 26.0. Results: The modified model showed appropriate goodness of fit (χ² = 369.90, χ² /degree of freedom = 2.09, SRMR = .09, RMESA = .07, CFI = .94, TLI = .93). The post-traumatic growth of cured patients with COVID-19 was explained through distress perception, self-disclosure, and deliberate rumination, with the explanatory power being 70.0%. Conclusion: This study suggests preparing a disaster psychology program involving experts who can activate deliberate rumination is necessary. Further, this study may serve as basic data for developing a program to enhance the post-traumatic growth of patients cured from COVID-19.

• 한국심리학회지 : 문화 및 사회문제
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• 제27권4호
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• pp.629-659
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• 2021

본 연구는 코로나 19 팬데믹 시기동안 한국인이 겪는 정서적 디스트레스에 영향을 미치는 심리·사회적 요인의 영향력을 서로 다른 두 시점에서 비교하였다. 1차 조사시기는 WHO에서 코로나 19 팬데믹을 선언하고, 대구 경북지역이 특별재난지역으로 선정되었던 2020년 4월 13일부터 4월 21일까지이며, 연구참여자 600명의 자료를 수집하였다. 2차 조사시기는 전 세계적으로 코로나 19가 재확산되고, 수도권에서 처음으로 집단감염이 확산되면서 일주일동안 수도권에서만 확진자가 1,000명이 넘었던 시점인 2020년 8월 21일부터 9월 2일까지 진행되었다. 1차 조사의 연구참여자 중 482명이 2차 조사에 응하였으며, 모든 자료는 온라인 설문을 통해 수집되었다. 본 연구는 시점별로 개인특성요인, 코로나 19에 대한 두려움과 사회활동 제약요인, 대인관계갈등 및 수입감소 요인이 코로나 19로 인한 디스트레스(스트레스, 우울, 불안, 분노) 경험에 미치는 영향을 알아보기 위해 위계적 회귀분석을 실시하였다. 그 결과, 두시점 모두에서 정서적 디스트레스에 영향을 미치는 요인으로는 성별, 삶의 질, '코로나 19 관련 정보 수시 확인', '코로나 19 이후 삶을 예측할 수 없어 두려움', '병원 이용의 어려움'이 확인되었다. 시점1에서만 유의한 변인으로 '공적일정에 차질', 시점 2에서만 유의한 변인으로는 연령, 감염취약성, '개인일정에 차질'이 확인되었다. 이를 토대로 논의 및 시사점이 제시되었다.

• 한국심리학회지 : 문화 및 사회문제
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• 제29권2호
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• pp.223-252
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• 2023

본 연구에서는 코로나 대유행 시기에 지각된 스트레스가 심리적 디스트레스(부정정서, 우울, 불안, 분노)에 미치는 영향에서 대처전략의 종단매개효과를 확인하고자 하였다. 또한 코로나 대유행 상황에서 각 연령별로 대처전략의 사용에 차이가 있었는지 살펴보았다. 이를 위해 8개월의 간격을 두고 두 번에 걸쳐 수집된 성인 941명의 두 시점 종단 자료를 활용하였다. 분석결과, 코로나 스트레스(시점1)는 심리적 디스트레스(시점2) 중 우울을 제외한 부정정서, 불안, 분노에 종단으로 영향을 끼치는 것으로 확인되었다. 종단매개효과 분석결과, 대처전략 중 부적응적 대처전략만(시점2)이 코로나 스트레스(시점1)와 심리적 디스트레스(시점2)의 관계에서 종단매개효과를 보이는 것으로 나타났다. 연령별 다집단 분석결과, 대처전략의 사용에 있어서 연령별 차이는 없는 것으로 나타났다. 본 연구는 코로나 대유행 상황에서 일반 성인의 심리적 디스트레스를 종단으로 살펴보았다는 점에서 의의를 지닌다. 마지막으로 본 연구의 한계점과 추후 연구를 위한 제언을 제시하였다.

• Journal of Ginseng Research
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• 제46권3호
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• pp.331-336
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• 2022

Coronavirus disease 2019 (COVID-19) exhibits various symptoms, ranging from asymptomatic to severe pneumonia or death. The major features of patients in severe COVID-19 are the dysregulation of cytokine secretion, pneumonia, and acute lung injury. Consequently, it leads to acute respiratory distress syndrome, disseminated intravascular coagulation, multiple organ failure, and death. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of COVID-19, influences nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3 (NLRP3), the sensor of inflammasomes, directly or indirectly, culminating in the assembly of NLRP3 inflammasome and activation of inflammatory caspases, which induce the inflammatory disruption in severe COVID-19. Accordingly, the target therapeutics for inflammasome has attracted attention as a treatment for COVID-19. Korean Red Ginseng (KRG) inhibits several inflammatory responses, including the NLRP3 inflammasome signaling. This review discusses the role of KRG in the treatment and prevention of COVID-19 based on its anti-NLRP3 inflammasome efficacy.

• Genomics & Informatics
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• 제21권2호
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• pp.16.1-16.14
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• 2023

Coronavirus disease 2019 (COVID-19) is a viral infection produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus epidemic, which was declared a global pandemic in March 2020. The World Health Organization has recorded around 43.3 billion cases and 59.4 million casualties to date, posing a severe threat to global health. Severe COVID-19 indicates viral pneumonia caused by the SARS-CoV-2 infections, which can induce fatal consequences, including acute respiratory distress syndrome (ARDS). The purpose of this research is to better understand the COVID-19 and ARDS pathways, as well as to find targeted single nucleotide polymorphism. To accomplish this, we retrieved over 100 patients' samples from the Sequence Read Archive, National Center for Biotechnology Information. These sequences were processed through the Galaxy server next generation sequencing pipeline for variant analysis and then visualized in the Integrative Genomics Viewer, and performed statistical analysis using t-tests and Bonferroni correction, where six major genes were identified as DNAH7, CLUAP1, PPA2, PAPSS1, TLR4, and IFITM3. Furthermore, a complete understanding of the genomes of COVID-19-related ARDS will aid in the early identification and treatment of target proteins. Finally, the discovery of novel therapeutics based on discovered proteins can assist to slow the progression of ARDS and lower fatality rates.

• Child Health Nursing Research
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• 제30권2호
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• pp.154-163
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• 2024

Purpose: This study is descriptive research aiming to identify factors influencing the stigma experienced by college students with coronavirus disease 2019 (COVID-19), focusing on COVID-19 pandemic stress, depression, and fear of negative evaluation as the main variables. Methods: An online survey was administered to 175 college students who had been diagnosed with COVID-19 from January to May 2022 and were enrolled in universities in Seoul, Cheongju, and Daegu, South Korea. The survey collected data on pandemic stress, depression, fear of negative evaluation, and stigma. The data were analyzed using the t-test, ANOVA, the Scheffe test, Pearson's correlation coefficients, and stepwise multiple regression in SPSS/WIN 26.0. Results: We analyzed differences in stigma scores based on general characteristics of the college students and found significant differences in stigma scores by age, major satisfaction, interpersonal satisfaction, date of COVID-19 confirmation, treatment modality, and recent subjective health condition. Factors influencing stigmatization were identified as COVID-19 pandemic stress, depression, date of COVID-19 confirmation, treatment modality, recent subjective health condition, and major satisfaction, with an overall explanatory power of 37.6%. Conclusion: This study is significant as it identifies emotional changes across various aspects of pandemic stress, depression, fear of negative evaluation, and stigma among college students who have been diagnosed with COVID-19. The findings of this study suggest the development of programs to reduce psychological distress and enhance mental health management skills among these students.

• 산업융합연구
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• 제20권10호
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• pp.103-111
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• 2022

본 연구의 목적은 코로나19 팬데믹 상황에서 농촌에 거주하는 중년 남성의 노화 불안에 영향을 미치는 요인을 파악하는 것이다. 본 연구의 설계는 서술적 조사연구를 이용하였다. 연구 대상자는 G 지역에 거주하는 만 45세 이상 64세 이하 중년 남성 180명이다. 자료는 SPSS WIN 프로그램을 이용하여 t-test, ANOVA, Pearson's correlation coefficient, 다중회귀분석을 이용하여 분석하였다. 회귀분석 결과 노화 불안에 영향을 미치는 요인은 스트레스(β=.10, p=.049), 경제적 어려움(β=.16, p=.007), 코로나19로 인한 심리적 고통(β=.18, p=.003), 가족 돌봄 부담(β=.50, p<.001)으로 확인되었으며(F=55.93, p<.001), 이들 변수의 설명력은 60.5%이었다. 추후 중년 남성의 노화 불안과 스트레스 관리를 위한 중재가 필요하며 코로나19로 인한 심리적 고통을 줄이고 경제적 어려움을 극복하기 위한 지원 정책 마련이 필요하다.