• Journal of Yeungnam Medical Science
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• v.39 no.3
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• pp.216-222
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• 2022

Background: This study assessed the psychological impact of the outbreak of coronavirus disease 2019 (COVID-19) on university hospital nurses. It provides an assessment of mental health issues, including depression, anxiety, distress, and burnout of nurses dealing directly and indirectly with COVID-19. Methods: In a web-based, cross-sectional study, 111 nurses from Daegu Catholic University Hospital in Korea were enrolled from August 4 to August 9, 2020. Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Impact of Event Scale-Revised, and Maslach Burnout Inventory were used to assess the psychological symptoms of depression, anxiety, psychological distress, and burnout among the study participants. Results: Of 111 nurses, 35 (31.5%), nine (8.1%), 26 (23.4%), and 49 (44.1%) experienced depression, anxiety, distress, and burnout, respectively. Nurses who performed COVID-19-related tasks were more likely to have moderate depression (related vs. unrelated, 52.0% vs. 25.6%; p=0.037). There were no differences in anxiety, distress, and burnout between nurses with and without COVID-19-related tasks. More than 50% of the participants showed receptive and positive attitudes toward caring for COVID-19 patients. Conclusion: Nurses who performed COVID-19-related tasks had a higher risk of depression. There were no significant differences in anxiety, distress, and burnout between the two groups. Since nurses who perform COVID-19-related tasks are more prone to psychological distress, continued psychiatric interventions are required for infectious disease outbreaks with a high mortality rate for healthcare workers who are emotionally vulnerable.

• Journal of Chest Surgery
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• v.55 no.4
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• pp.357-360
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• 2022

Patients with severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) may exhibit pulmonary fibrosis after the viral illness resolves. Some of these patients may experience severe functional lung impairment, and thus require transplants to prevent death or maintain a tolerable quality of life. Considering the reversibility of COVID-19 ARDS, lung transplant candidates are observed for 1-2 months and must be selected very carefully before transplantation. As the short-term outcomes of such patients are comparable to those of patients with other indications for transplantation, lung transplantation should be actively considered.

• Journal of Korean Public Health Nursing
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• v.36 no.3
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• pp.334-346
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• 2022

Purpose: This survey was conducted to investigate the level of coronavirus disease 2019 (COVID-19)-related peritraumatic distress and job stress among clinical nurses and evaluate their effects on nursing performance. Methods: The participants were 115 nurses from 5 hospitals in 3 regions in Korea. The peritraumatic distress index (PDI), job stress, and nursing performance scales were used for the analysis. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, and multivariate regression analysis. Results: The level of peritraumatic distress of nurses was scored at 22.8 ± 9.26 (range 0 to 45). The level of job stress was scored at 2.69 ± 0.51 (range 1.3 to 3.7). The level of nursing performance was scored at 3.73 ± 0.51(range 1.76 to 5.0). Peritraumatic distress was observed to be positively correlated with job stress (r=.408, p<.001). However, peritraumatic distress and job stress were not correlated with nursing performance. In multivariate regression, the only variable seen to affect nursing performance was the work experience of the nurses. Work experience levels of five to fifteen years were observed to have a significant positive effect on nursing performance. Conclusion: The work experience of nurses directly influenced nursing performance during the pandemic period. Thus, to retain more nurses and to improve nursing performance, it would be necessary to develop various strategies to decrease their peritraumatic distress and job stress caused by the pandemic.

• Journal of Korean Academy of Nursing
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• v.53 no.3
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• pp.309-323
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• 2023

Purpose: This study aimed to develop and test a model for posttraumatic growth among cured patients with COVID-19. This model was based on Calhoun and Tedeschi's Posttraumatic Growth model and a literature review. Methods: The participants comprised 223 patients cured from COVID-19 who were ≥ 19 years of age. The data were collected through an online questionnaire from March 21 to 24, 2022. The assessment tools included the Impact of Event Scale: Revised Korean version, the Connor-Davidson Resilience Scale, the Distress Disclosure Index, the Multidimensional Scale of Perceived Social Support, the Korean version of the Event-related Rumination Inventory, and the Korean version of the Post-traumatic Growth Inventory. Data were analyzed using the IBM SPSS version 24.0 and IBM AMOS 26.0. Results: The modified model showed appropriate goodness of fit (χ² = 369.90, χ² /degree of freedom = 2.09, SRMR = .09, RMESA = .07, CFI = .94, TLI = .93). The post-traumatic growth of cured patients with COVID-19 was explained through distress perception, self-disclosure, and deliberate rumination, with the explanatory power being 70.0%. Conclusion: This study suggests preparing a disaster psychology program involving experts who can activate deliberate rumination is necessary. Further, this study may serve as basic data for developing a program to enhance the post-traumatic growth of patients cured from COVID-19.

• Korean Journal of Culture and Social Issue
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• v.27 no.4
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• pp.629-659
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• 2021

This study compared the influences of Korean psycho-social experiences on emotional-distress(stress, depression, anxiety, anger) of Koreans between two-periods during COVID-19. First, an online survey was conducted among 600 participants between April 13, 2020 and 21, while WHO had declared the pandemic, and Daegu-Gyungbuk were declared as a special-disaster area. Second, an online survey was conducted among 482 participants out of 600 study participants from the first study during August 21 to September 2, while COVID-19 re-spreaded around the world, and total confirmed cases were over 1,000 for a week in Seoul-Gyeonggi province. Hierarchical-regression analysis was used to determine the influence of personal characteristics, fear and social constraints, relationship conflict and income-decreasing factors on stress, depression, anxiety, anger in the two-time points. Results suggest that gender, quality-of-life, 'frequent information-checking about COVID-19', 'fear of unpredictability' and 'difficulties on hospital treatment access' predicted distress(stress, depression, anxiety, anger) at both Time1 and 2. 'Difficulties with official schedule' predicted distress at Time 1, and age, vulnerability to infection and difficulties with personal schedules predicted distress(stress, depression, anxiety, anger) at Time 2. Based on the reseults, implications and recommendations were presented.

• Korean Journal of Culture and Social Issue
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• v.29 no.2
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• pp.223-252
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• 2023

The aim of this study is to examine the longitudinal mediation effect of coping strategies(emotion-focused, problem-focused, and maladaptive) on the relationship between perceived stress during the COVID-19 andemic and psychological distress(negative affect, depression, anxiety, and anger). ). Also, This study sought to find generational differences between coping strategies used during the COVID-19 pandemic. The participants were 941 adult aged between twenties and seventies. The final participants were recruited on two separated longitudinal time points, Time 1 and Time 2. The result were as follows: Only Maladaptive coping strategy(Time 2) had a mediating effect on the relationship between COVID-19 stress(Time 1) and psychological distress(Time 2). . The result of the generation-based multi-group analysis did not yield significant differences in the use of coping strategies. This study is meaningful that it longitudinally examined the psychological distress of adults during the COVID-19 pandemic. Implications, limitations and directions for future research are presented.

• Journal of Ginseng Research
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• v.46 no.3
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• pp.331-336
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• 2022

Coronavirus disease 2019 (COVID-19) exhibits various symptoms, ranging from asymptomatic to severe pneumonia or death. The major features of patients in severe COVID-19 are the dysregulation of cytokine secretion, pneumonia, and acute lung injury. Consequently, it leads to acute respiratory distress syndrome, disseminated intravascular coagulation, multiple organ failure, and death. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of COVID-19, influences nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3 (NLRP3), the sensor of inflammasomes, directly or indirectly, culminating in the assembly of NLRP3 inflammasome and activation of inflammatory caspases, which induce the inflammatory disruption in severe COVID-19. Accordingly, the target therapeutics for inflammasome has attracted attention as a treatment for COVID-19. Korean Red Ginseng (KRG) inhibits several inflammatory responses, including the NLRP3 inflammasome signaling. This review discusses the role of KRG in the treatment and prevention of COVID-19 based on its anti-NLRP3 inflammasome efficacy.

• Genomics & Informatics
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• v.21 no.2
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• pp.16.1-16.14
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• 2023

Coronavirus disease 2019 (COVID-19) is a viral infection produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus epidemic, which was declared a global pandemic in March 2020. The World Health Organization has recorded around 43.3 billion cases and 59.4 million casualties to date, posing a severe threat to global health. Severe COVID-19 indicates viral pneumonia caused by the SARS-CoV-2 infections, which can induce fatal consequences, including acute respiratory distress syndrome (ARDS). The purpose of this research is to better understand the COVID-19 and ARDS pathways, as well as to find targeted single nucleotide polymorphism. To accomplish this, we retrieved over 100 patients' samples from the Sequence Read Archive, National Center for Biotechnology Information. These sequences were processed through the Galaxy server next generation sequencing pipeline for variant analysis and then visualized in the Integrative Genomics Viewer, and performed statistical analysis using t-tests and Bonferroni correction, where six major genes were identified as DNAH7, CLUAP1, PPA2, PAPSS1, TLR4, and IFITM3. Furthermore, a complete understanding of the genomes of COVID-19-related ARDS will aid in the early identification and treatment of target proteins. Finally, the discovery of novel therapeutics based on discovered proteins can assist to slow the progression of ARDS and lower fatality rates.

• Child Health Nursing Research
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• v.30 no.2
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• pp.154-163
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• 2024

Purpose: This study is descriptive research aiming to identify factors influencing the stigma experienced by college students with coronavirus disease 2019 (COVID-19), focusing on COVID-19 pandemic stress, depression, and fear of negative evaluation as the main variables. Methods: An online survey was administered to 175 college students who had been diagnosed with COVID-19 from January to May 2022 and were enrolled in universities in Seoul, Cheongju, and Daegu, South Korea. The survey collected data on pandemic stress, depression, fear of negative evaluation, and stigma. The data were analyzed using the t-test, ANOVA, the Scheffe test, Pearson's correlation coefficients, and stepwise multiple regression in SPSS/WIN 26.0. Results: We analyzed differences in stigma scores based on general characteristics of the college students and found significant differences in stigma scores by age, major satisfaction, interpersonal satisfaction, date of COVID-19 confirmation, treatment modality, and recent subjective health condition. Factors influencing stigmatization were identified as COVID-19 pandemic stress, depression, date of COVID-19 confirmation, treatment modality, recent subjective health condition, and major satisfaction, with an overall explanatory power of 37.6%. Conclusion: This study is significant as it identifies emotional changes across various aspects of pandemic stress, depression, fear of negative evaluation, and stigma among college students who have been diagnosed with COVID-19. The findings of this study suggest the development of programs to reduce psychological distress and enhance mental health management skills among these students.

• Journal of Industrial Convergence
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• v.20 no.10
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• pp.103-111
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• 2022

The purpose of this study was to identify the influencing factors on aging anxiety by middle-aged men in rural areas during the COVID-19 pandemics. The design of this study was descriptive survey study. The participants were 180 middle-aged men aged 45 to 64 living in G province. Collected data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient and multiple regression analysis with SPSS statistics 26.0 program. As a result of regression analysis, As a result of regression analysis, influencing factors on aging anxiety were stress(β=.10, p=.004), economic difficulties (β=.16, p=.007), COVID-19 psychological distress(β=.18, p=.003), family care burdens(β=.50, p<.001), and the explanatory power of the variables was 60.5%(F=55.93, p<.001). In the future, interventions are needed to manage aging anxiety and stress in middle-aged men, and support policies are needed to reduce psychological distress and overcome economic difficulties caused by COVID-19.