• Title/Summary/Keyword: COVID-19 Crisis

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Small Molecule Drug Candidates for Managing the Clinical Symptoms of COVID-19: a Narrative Review

  • Yun, Chawon;Lee, Hyun Jae;Lee, Choong Jae
    • Biomolecules & Therapeutics
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    • v.29 no.6
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    • pp.571-581
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    • 2021
  • Towards the end of 2019, an atypical acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China and subsequently named Coronavirus disease 2019 (COVID-19). The rapid dissemination of COVID-19 has provoked a global crisis in public health. COVID-19 has been reported to cause sepsis, severe infections in the respiratory tract, multiple organ failure, and pulmonary fibrosis, all of which might induce mortality. Although several vaccines for COVID-19 are currently being administered worldwide, the COVID-19 pandemic is not yet effectively under control. Therefore, novel therapeutic agents to eradicate the cause of the disease and/or manage the clinical symptoms of COVID-19 should be developed to effectively regulate the current pandemic. In this review, we discuss the possibility of managing the clinical symptoms of COVID-19 using natural products derived from medicinal plants used for controlling pulmonary inflammatory diseases in folk medicine. Diverse natural products have been reported to exert potential antiviral effects in vitro by affecting viral replication, entry into host cells, assembly in host cells, and release. However, the in vivo antiviral effects and clinical antiviral efficacies of these natural products against SARS-CoV-2 have not been successfully proven to date. Thus, these properties need to be elucidated through further investigations, including randomized clinical trials, in order to develop optimal and ideal therapeutic candidates for COVID-19.

Influence of COVID-19 Anxiety on Vigor and Innovative Work Behavior: Mediated Moderation of Flexible Work Arrangement

  • Jonghun Sun;Yoon Soo Jun
    • Science of Emotion and Sensibility
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    • v.26 no.2
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    • pp.3-12
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    • 2023
  • The present study examines the impact of COVID-19 anxiety on employees' psychological resources and behaviors, drawing on the conservation of resources theory. We also investigate whether flexibility in work contexts has a meaningful effect on employees' responses to the pandemic. A total of 284 working adults participated in an online survey consisting of self-reporting questionnaires that assessed levels of COVID-19 anxiety, vigor, innovative work behavior, and flexible working arrangements. The results showed that the level of vigor mediated the positive relationship between COVID-19 anxiety and innovative work behavior, and the perceived level of flexible working arrangements moderated this mediation effect positively. The findings highlight the importance of considering employees' psychological resources and work arrangements in managing the negative impact of COVID-19-related anxiety. This study provides theoretical and practical implications for organizations to better understand the psychological processes that employees undergo during a crisis. Further research on diverse work settings and cultural backgrounds is needed to expand on the present findings.

Running of high patient volume radiation oncology department during COVID-19 crisis in India: our institutional strategy

  • Gupta, Manoj;Ahuja, Rachit;Gupta, Sweety;Joseph, Deepa;Pasricha, Rajesh;Verma, Swati;Pandey, Laxman
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.93-98
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    • 2020
  • Purpose: Due to COVID 19 pandemic, the treatment of cancer patients has become a dilemma for every oncologist. Cancer patients are at an increased risk of immunosuppression and have a higher risk to acquire any infection. There are individual experiences from some centers regarding the management of cancer patients during such a crisis. So we have developed our institutional strategy to balance between COVID and cancer management. Materials and Methods: Radiation Oncology departmental meeting was held to prepare a consensus document on Radiotherapy schedules and department functioning during this pandemic. Results: Strategies were taken in form of following areas were steps need to be taken to decrease risk of infection, categorise treatment on the basis of priority, radiotherapy schedules modification, academic meetings and management of COVID positive patient/personnel in Radiation Oncology department. Conclusion: We hope to strike the balance in overcoming both the battles and emerge as winners. Stringent long term follow up will be done for assessing the response or any unforeseen treatment related sequelae.

The Effect of COVID-19 Pandemic on University Libraries: Forced on the Perception of University Librarians (코로나 19가 대학도서관에 미치는 영향에 관한 연구 - 대학도서관 사서의 인식을 중심으로 -)

  • Chung, Jae-Young;Oh, Se-Hoon
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.32 no.3
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    • pp.93-114
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    • 2021
  • COVID-19 has been affecting the library, not to mention society as a whole. Especially, there are many changes in the role and service of the university libraries as all the classes of the universities are turned into non-face-to-face and the use of the university libraries is restricted. The changes in users' use of information and communication behavior due to COVID-19 could be an opportunity for new utilization of human and material resources the university libraries have and for the development of services. However, on the contrary, the university libraries could face another crisis if they fail to respond appropriately to current changes. Therefore, it is necessary to grasp, analyze the impact of COVID-19 and plan how to respond. A survey on the effects of COVID-19 and the response of the university libraries and the perceptions of the university libraries found that most university libraries are responding appropriately to COVID-19. However, a survey on the perceptions of the present and future of the university libraries under COVID-19 showed that many survey respondents think COVID-19 would have a negative impact on the university libraries. This means that the changes caused by COVID-19 are causing a crisis and anxiety in the university libraries. Therefore, by working hard together, the university libraries need to present the university libraries' new role, service and direction in the post-COVID-19 era as well as responding to the current situation.

The Effect of Stress Caused by the Spread of COVID-19 on the Quality of Life in University Students: The Moderating Effect of Family Health (COVID-19의 유행으로 인한 스트레스가 대학생의 삶의 질에 미치는 영향: 가족건강성의 조절효과)

  • Kim, Hyun-Kyung
    • The Journal of Korean Society for School & Community Health Education
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    • v.22 no.3
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    • pp.17-27
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    • 2021
  • Objectives: As COVID-19 drags on, university students experience more stress and feel more anxious about their studies and career plans. Against the backdrop, this study aims to analyze the moderating effect of family health on the relationship between the spread of COVID-19 and the quality of life in university students. Methods: In order to achieve the purpose of this study, the results of an online survey performed with 216 university students in cities K and D were analyzed using frequency analysis, factor analysis, correlation analysis, regression analysis, and moderating effect analysis. Results: It was found that COVID-19 stress had a significant negative effect on the quality of life in university students, while family health showed a significant positive effect. In addition, the moderating effect of family health was statistically significant on the relationship between COVID-19 stress and the quality of life in university students. Conclusions: This study found that family health plays an essential role as a safety net in reducing stress and improve the quality of life in university students amid the social crisis of the COVID-19 pandemic. In this regard, it is required to develop various programs for communication with parents, including parent-child communication techniques.

Capital Structure of Malaysian Companies: Are They Different During the COVID-19 Pandemic?

  • MOHD AZHARI, Nor Khadijah;MAHMUD, Radziah;SHAHARUDDIN, Sara Naquia Hanim
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.4
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    • pp.239-250
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    • 2022
  • This study examined the level of capital structure and its determinants of publicly traded companies in Malaysia before and after the COVID-19 pandemic. The data for this study was examined using Python Programming Language and time-series financial data from 2,784 quarterly observations in 2019 and 2020. The maximum debt is larger before the COVID-19 period, according to the findings. During the COVID-19 period, short-term debts and total debts have both decreased slightly. However, long-term debts have increased marginally. As a result, this research demonstrates that the capital structure has changed slightly during the COVID-19 period. The findings imply that independent of the capital structure proxies, tangibility, liquidity, and business size had an impact on capital structure in both periods. It was found that profitability had a significant impact on total debts both before and after the COVID-19 crisis. While higher-profit enterprises appear to have lesser short-term debts before the COVID-19 periods, they are also more likely to have lower long-term debts during the COVID-19 periods. Even though growing companies tend to have higher short-term debts and thus total debts during those periods, longterm debts are unaffected by potential growth.

The Contagion of Covid-19 Pandemic on The Volatilities of International Crude Oil Prices, Gold, Exchange Rates and Bitcoin

  • OZTURK, M. Busra Engin;CAVDAR, Seyma Caliskan
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.3
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    • pp.171-179
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    • 2021
  • In the international markets, financial variables can be volatile and may affect each other, especially in the crisis times. COVID-19, which began in China in 2019 and spread to many countries of the world, created a crisis not only in the global health system but also in the international financial markets and economy. The purpose of this study is to analyze the contagious effect of the COVID-19 pandemic on the volatility of selected financial variables such as Bitcoin, gold, oil price, and exchange rates and the connections between the volatilities of these variables during the pandemic. For this aim, we use the ARMA-EGARCH model to measure the impact of volatility and shocks. In other words, it is aimed to measure whether the impact of the shock on the financial variables of the contagiousness of the epidemic is also transmitted to the markets. The data was collected from secondary and daily data from September 2th 2019 to December 20th, 2020. It can be said that the findings obtained have statistically significant effects on the conditional variability of the variables. Therefore, there are findings that the shocks in the market are contaminated with each other.

Information Support for Economic Growth and Security under the Influence of COVID-19

  • Shenderivska, Lina;Lazorenko, Taisiіa;Butkevych, Oksana;Khomenko, Andrii;Shuprudko, Nataliia
    • International Journal of Computer Science & Network Security
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    • v.22 no.1
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    • pp.206-212
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    • 2022
  • The main purpose of the article is to study the peculiarities of the formation of information support mechanisms for economic growth and security under the influence of COVID-19. The cyclical nature of economic growth is a well-established and proven fact. In this context, one of the main tasks of the state is to develop measures to mitigate the impact of economic crises on the entire economic system of the state, individual economic entities, as well as to introduce anti-crisis mechanisms and tools to support the economy. When the cyclical nature of economic crises coincides with destabilizing processes in society, such as natural disasters, military actions or epidemics, the role of the state and adequate information support for economic growth is sharply actualized. As a result, an analysis was made of the main aspects of information support for economic growth and security in the context of COVID-19.

Neither External nor Multilateral: States' Digital Diplomacy During Covid-19

  • Wu, Di;Sevin, Efe
    • Journal of Public Diplomacy
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    • v.2 no.1
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    • pp.69-96
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    • 2022
  • How does a public health crisis play into the digital rhetoric of states? As Covid-19 is presenting a situation in which countries need to manage the international environment in a relatively short period, their practices could signal how digitization is going to influence public diplomacy in the longer run. This paper explores state public diplomacy in the context of a public health crisis. It develops a theoretical framework of public diplomacy on social media through how and what states communicated during the first year of the Covid-19 pandemic. Through keyword and hashtag analyses, we identify two patterns. First, states usually regard social media as an instrument for domestic communication rather than public diplomacy. The international impact of messaging has not been prioritized or well-recognized. Social media platforms such as Twitter have global outreach and messaging can be seen by audiences all over the world. Messages intended for the domestic audience could have an international impact. Thus, any communication on digital platforms should consider their public diplomacy outcomes. Second, while social media platforms are claimed to be for networking at different levels, states tend to connect with other states rather than with international organizations during the pandemic. States do not like to mention international organizations like the WHO and the UN on Twitter. Instead, they were either busy dealing with internal problems or cooperating with another state to combat the virus.

A Preliminary Study on the Expansion of Donations by Non-Profit Organizations after the COVID-19 Crisis: With Focusing on the Survey on the Citizens' Perception of Donations (COVID-19 이후 비영리조직의 기부금품 모집 확대 방안에 대한 기초연구: 일반시민의 기부 인식을 중심으로)

  • Jung, Hee Young;Lee, Jung Jae
    • Journal of Information Technology Services
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    • v.21 no.3
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    • pp.105-116
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    • 2022
  • The purpose of this study is to provide basic data to present the direction of donation collection activities of non-profit organizations after the COVID-19 crisis by examining the perception of donations from the general public's perspective. The researchers conducted a convenience sampling of general citizens in South Korea, and the survey had been taken by sending e-mails for two weeks from November 11 to November 24, 2020. The total number of questionnaires that we send were 397, however 314 questionnaires were used for analysis, excluding 83 questionnaires that seemed insincerely marked. According to analysis result, non-profit organizations need to strengthen their digital capability in response to the changes in the fund-raising methods in the era of digital transformation. In addition, these factors such as transparency, accountability, and the interaction with donors for sustaining and improving their loyalty are turned out to be crucial. We hope that the results of this study will present the direction of the donation collection strategy of non-profit organizations and be used as basic data for further research.