• Journal of Preventive Medicine and Public Health
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• 제13권1호
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• pp.53-66
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• 1980

The editorials of the leading newspapers may reflect as well as help formulate the public opinions to a significant degree. Bearing this in mind, this study was carried out to provide information useful in formulating such public health policies that could practically meet the social interests and demands in health appearing in the editorials of the newspapers. This analysis covered the editorials of 5 leading newspapers such as Donga Ilbo, Chungang Ilbo, Hankook Ilto, Chosun Ilbo and Seoul Shinmoon for about 10 years from Jan. 1st, 1970 through Oct. 31th, 1979. The major findings are as follows: 1. The total number of health-concerned editorials in the five daily papers for the period was 1,768 or occupied 6.4% of the total editorials of the same sources. The increasing trend of frequnecy of the health-concerned editorials since 1976 indicates the increment of social interests and demands in health. Analysing the contents, environmental pollution received the greatest attention in those editorials, which was followed by medical affairs, environmental sanitation, and disease control in order in terms of frequency of appearance. However, there was a tendency that the interests in the environmental pollution, medical affairs and social welfare tended to increase year by year, whereas those in environmental hygiene and disease control comparatively decreased. 2. Motives of dealing with the health-concerned editorials were provided by announcement of the governmental policies and implementation for 25.6% and by out-breaks of the relevant events for 23.9%. This tendency coincides with the general characteristics of the editorials that reflect the timely issues. Closely analysing, however, the fact that the motives engendered by the out-breaks of the relevant events or by the season concerned comparatively tended to decrease as years pass by, indicates that the editorials tend more to seek the future-oriented demands in health rather than the current issue-oriented. 3. The editorials appeared to be more concerned with the governmental policies. 95.7% of all the editorials analysed were addressed to the government. This signifies the role of government in the field of public health and medical affairs. Their attitudes toward health-related policies of the government were much more negative than the other editorials that were addressed to the government in other fields. This suggests that the governmental interests in health were neither sufficient nor fair. 4. What the editorials most stressed were; (1) increment of governmental interests in health, (2) improvement of the governmental health administration, (3) enriching the basic statistics, and (4) development of various technologies pertinent to health affairs and disease control, and so forth. However, must of their suggestions were not concrete but rather abstract and conceptual. 5. The editorials also expressed strong interests in research area. The areas of the needed research most suggested by items are; (1) development of effective health care delivery system, (2) establishment of more practical system of calculating medical cost, (3) implementation of effective policies to control degenerative diseases, (4) division of medical care services and pharmaceutical services systems, (5) effective ways to prevent Co poisoning accidents, (6) changing status of environmental pollution and its effects upon health, and (7) status of occupational diseases, and so forth. 6. There were some editorials -not small in quantity -that have risk to mislead the public opinions as well as the health policies due to lack of professional knowledge of the writers. It is desirable to establish some kind of mechanism that screens the erroneous contents of the editorials to help prevent misleading opinions.

• 한국식품위생안전성학회지
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• 제18권4호
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• pp.189-194
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• 2003

기존에 식품의 저장성 향상을 우해 사용되어졌던 방법들의 문제점들을 최소화하고 보다 효과적인 식품저장을 위해 전통적으로 식용되어 왔으며 그 안전성이 확보된 프로폴리스를 대상으로 대표적인 식품 부패 미생물에 대한 생육억제활성을 식용되어 왔으며 그 안전성이 확보된 프로폴리스를 대상으로 대표적인 식품 부패 미생물에 대한 생육억제활성을 탐색하고 건강 지향적인 식품보존제로서 이를 식품에 적용하여 보다 좋은 품질의 가공식품개발에 활용코자 본 연구를 진행하였다. 프로폴리스 에탄올 추출물의 일반성분 분석 결과를 보면 19.41% 수분, 0.39% 조단백, 5.12% 조지방, 0.15% 조회분의 결과를 보여주었다. 프로폴리스는 에탄올 60%, 에탄올 80% 추출물에서는 높은 추출율을 보였다. 프로폴리스 에탄올 추출물에 의한 항균성은 100% 에탄올 추출물로 실험한 처리구에서 높은 항균 효과를 나타내어 이를 사용하여 유해 미생물들에 대한 농도별 항균 효과를 살펴보았다. 프로폴리스 추출물로 유해미생물을 처리했을 때 Bacillus subtilis, Micrococcus luteus는 1~2 mg/mL로 처리 시 생균수가 1~4log 감소하였고, E. coli는 3mg/mL로 처리 시, Bacillus cereus는 1~2 mg/mL의 노도로 처리 시 대조군에 비해 생균수가 2log 감소하였다. Staphylococcus aureus와 Shigella sonnei의 사멸효과는 0.1~3 mg/mL의 농도에서 생균수가 2~4log 감소하였다. Erwinia rhapontici의 사멸효과는 2 mg/mL 농도로 실험했을 때 2 log 정도 생ㅇ육저해효과를 보였고, Salmonella choleraesuis, Vibrio parahaemolyticus에서의 사멸효가는 크게 관찰할 수 없었다. 프로폴리스는 그램양성균에 대한 사멸효과가 그램음성균에 대한 효과 보다 더 우수하였다.

• 한국수산과학회지
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• 제46권6호
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• pp.733-738
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• 2013

This study investigated the inhibitory effect of high hydrostatic pressure (HHP) treatments on histamine production in mackerel Scomber japonicus. Changes in viable cell counts, histamine contents, pH and VBN of mackerel fillet (stored at $4^{\circ}C$ for 25 days) were examined under HPP (200, 300, and 400 MPa). HPP treatments reduced viable cell counts by 2-3 log cycles during storage. Viable cells of mackerels treated with 400 MPa did not appear for 5 days. Histamine production was nearly suppressed by 300 and 400 MPa HPP treatments after 25 days. Furthermore, mackerels treated with HPP showed significantly lower VBN values compared with the control. Additionally, pH values were not affected by the treatments during storage periods. These results suggest that HPP treatment decreased histamine contents in mackerel muscles. Based on our results, HPP treatment may reduce scombroid fish poisoning by decreasing histamine production in mackerel during $4^{\circ}C$ storage.

• 한국식품영양과학회지
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• 제42권8호
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• pp.1263-1269
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• 2013

한약재 및 해조류 추출물에 대한 Photobacterium phosphoreum의 항균력을 측정한 결과, 오미자 열수 및 에탄올 추출물과 감태 및 비틀대 모자반 에탄올 추출물이 항균력을 나타내었으며 비틀대 모자반과 감태 에탄올 추출물이 각각 0.015625 mg/mL, 0.125 mg/mL의 최소저해농도를 나타내었다. P. phosphoreum 유래 HDC의 저해 효과를 측정한 결과, 감태와 대황 에탄올 추출물이 1 mg/mL에서 각각 32%, 25%의 높은 저해활성을 나타내었다. P. phosphoreum에 대해 항균력과 HDC 저해 효과를 나타낸 천연물을 고등어육에 첨가한 후 균주를 접종하여 생균수 및 histamine 생성량을 측정한 결과, 저장일차가 증가함에 따라 처리구에서 균수가 크게 감소하였다. Histamine의 함량도 다소 감소하였지만 주로 항균활성에 의해 histamine이 저해된 것으로 나타났다.

• 대한임상독성학회지
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• 제13권1호
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• pp.19-24
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• 2015

Purpose: Many patients who are acutely poisoned with organophosphorus pesticides have co-ingested alcohol. The purpose of this study was to identify the factors that influence mortality in organophosphate intoxication and the differences between alcohol coingested patients and non-coingested patients, looking at vital signs, length of admission, cholinesterase activity, complications, and mortality. Methods: All patients visiting one Emergency Department (ED) with organophosphate intoxication between January 2000 and December 2012 were reviewed retrospectively. The patients were divided into two groups, alcohol coingested group and non-coingested group. Results: During the study period, 136 patients (alcohol coingested group, 95 patients; non-coingested group, 41 patients) presented to the ED with organophosphate intoxication. Seventy-one alcohol coingested patients (74.1%) vs. 16 non-coingested patients (39.0%) received endotracheal intubation, with results of the analysis showing a clear distinction between the two groups (p=0.001). Twenty-three alcohol coingested patients (24.2%) vs. 1 non-coingested patient (2.4%) required inotropics, indicating a significant gap (p=0.002). Twenty-eight alcohol coingested patients (29.5%) vs. 2 non-coingested patients (4.9%) died, with results of the analysis showing a clear distinction between the two groups (p=0.002). Conclusion: In cases of organophosphate intoxication, alcohol coingested patients tended to receive endotracheal intubation, went into shock, developed central nervous system complications, and more died.

• 대한임상독성학회지
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• 제16권1호
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• pp.25-32
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• 2018

Purpose: Methamphetamine is an ongoing illegal drug problem worldwide, and its use in South Korea has spread over the last few years. In this study, a clinical review of patients who visited emergency medical centers with positive methamphetamine tests was conducted. Methods: Patients underwent methamphetamine screening based on physician suspicion over a period of 13 years. Their patient characteristics, clinical features, and drug administration properties were described. Results: A total of 297 patients were included, with 19 positive methamphetamine results. Patient age ranged from 21 to 84, with a mean of 37.52. Additionally, 13 were male and 6 were female. The mean BP, PR, RR were 131/82 mmHg, 94/min, 20/min. Saturation levels were all over 95%. Five patients had a psychiatric history. Patient showed varied symptoms ranging from mental changes to chest discomfort. In addition, seven showed abnormal electrocardiography findings and one showed elevated cardiac enzyme levels. Other laboratory results revealed no significantly abnormal results. Six patients also suffered from related trauma. The majority of patients consumed the methamphetamine orally, with unknown motivation at unknown locations. Most were transported by 119 and six patients co-ingested other drugs. Conclusion: Patients who showed positive results to a methamphetamine screening test in Korea visited the emergency medical center mostly by 119 and were unaware of or reluctant to reveal the fact that they had ingested methamphetamine. Emergency physicians should be more aware of the possibility that a patient may have consumed methamphetamine.

• 한국식품영양과학회지
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• 제44권7호
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• pp.1084-1089
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• 2015

고품질 감귤 가공품 개발을 위하여 감귤에 7종의 유산균을 각각 접종하여 10일간 배양하면서 0, 3, 5, 7, 10일째의 발효물의 생리활성을 분석하였다. 병원성 미생물에 대한 감귤 발효물의 항균 활성을 측정한 결과 김치에서 분리한 유산균인 CL-1과 CL-2의 발효물이 발효기간이 길어질수록 강한 항균 활성이 나타났다. 또한 각 감귤 발효물의 항고혈압 활성을 ACE 저해능으로 분석하였을 때 CL-1과 CL-2의 발효물이 발효기간이 길수록 높은 활성을 나타내었다. CL-1과 CL-2 균주를 16S rRNA gene의 구조로 분자계통학적 유연관계를 파악한 결과 각각 Pediococcus acidilactici 및 Lactobacillus sakei와 99% 이상의 상동성을 가지는 것을 확인할 수 있었다. 이상의 결과는 감귤을 P. acidilactici와 Lac. sakei로 발효하여 항균력과 항고혈압능이 증진된 가공품의 제조에 활용이 가능함을 시사한다.

• 전기화학회지
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• 제10권4호
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• pp.301-305
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• 2007

연료전지 운전 중에 스택(stack) 분리판 접착부위나 다른 경로로 부동액이 누설될 경우에는 화학적 반응에 영향을 주어 성능의 저하가 발생할 수 있다. 본 연구에서는 부동액이 누설되었을 경우의 성능 거동을 관찰하는 실험을 수행하였다. $400mA/cm^2$ 전류밀도 조건에서 마이크로 펌프를 이용하여 부동액을 주입하였으며 상대습도 100%/100%와 수소와 공기의 양론비는 1.5/2.0으로 고정하여 실험을 수행하였다. 3 cell stack을 이용하여 부동액을 주입한 후 정전류 회복 실험을 수행한 결과 cathode측에 부동액을 주입하였을 경우에는 성능이 회복되었고 anode측에 부동액을 주입하였을 경우에는 성능이 회복되기 어려운 것으로 나타났다. Anode측이 회복되지 못하는 이유로는 ethylene glycol의 산화반응에서 발생하는 불순물에 의한 피독 현상과 GDL과 3상 계면에 ethylene glycol이 물리적으로 흡착하였을 경우 반응에 필요한 연료 공급의 방해로 인한 성능 저하를 예상할 수 있다. 성능 저하에 영향을 주는 두 가지 변수를 확인하는 실험을 수행하였다. 회복 실험은 anode측에 water pump를 이용하여 질소 기체와 물을 동시에 공급하는 방법으로 실험을 수행하였고, 1시간 간격으로 성능 회복 유무를 확인하였다. 성능 평가는 polarization curve, cyclic voltammetry(CV), electrochemical impedance spectroscopy(EIS)를 사용하였으며, 정량분석은 gas chromatography를 이용하여 분석하였다. 부동액 주입 후 성능은 크게 저하되었고 정전류 회복 실험에서도 성능 회복은 미미하게 나타났다. 이 후 물 주입회복 실험을 수행하였고 회복 실험을 수행한 2시간 이후에는 93% 이상의 회복을 관찰할 수 있었다.

• Journal of Preventive Medicine and Public Health
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• 제16권1호
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• pp.153-156
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• 1983

1950년(年) 이후(以後) 무연탄(無煙炭)으로 만든 연탄(煉炭)을 취사(炊事), 난방용(煖房用)으로 가정(家庭)에서 광범위(廣範圍)하게 사용(使用)하게 되면서 연탄(煉炭)가스내(內)의 일산화탄소(一酸化炭素)로 인(因)한 중독사고(中毒事故)가 빈발(頻發)하여 심각(深刻)한 국민보건(國民保健)의 문제(問題)가 되어왔다. 저자(著者)들의 실태조사(實態調査)(1975년도(年度))에 의(依)하면 서울특별시일원(特別市一圓)에 있어 일산화탄소중독(一酸化炭素中毒)의 년간발생(年間發生)은 인구(人口), 10만당(萬當) 경증(輕症) 260명(名), 혼수상태(昏睡狀態)의 중증중독(重症中毒) 45명(名), 사망(死亡) 1명(名)으로 위험인구(危險人口)를 3,000만명(萬名)으로 하였을 때 전국적(全國的)으로 일산화탄소중독(一酸化炭素中毒)의 추정발생수(推定發生數)는 년간(年間) 경증(輕症) 78만명(萬名), 중증(重症) 13만(萬) 5천명(千名), 사망(死亡) 3,000명(名)으로 그 피해(被害)의 규모(規模)가 100만을 육박(肉薄)하는 가공(可恐)할 수자(數字)를 보여주고 있다. 저자(著者)들은 이러한 심각(深刻)한 국민보건(國民保健)의 문제(問題)를 우선(于先) 실천가능(實踐可能)한 제이차예방(第二次豫防)에 역점(力點)을 두어 고압산소요법(高壓酸素療法)을 보급(普及)할 목적(目的)으로 일인용고압산소장치(一人用高壓酸素裝置)를 개발(開發)하고 1969년(年) 1월(月)에 서울대학교병원(大學校病院)에 고압산소치료실(高壓酸素治療室)을 개설(開設)하여 급성일산화탄소(急性一酸化炭素) 중독환자(中毒患者)에 대(對)한 응급치료(應急治療)를 실시(實施)하여 1978년(年)까지 10년간(年間)의 치료결과(治療結果)를 요약(要約)한바 다음과 같다. 1. 총치료환자수(總治療患者數)는 2,242명(名)이고 회복(回復)된 수(數)는 2,202명(名)으로 98.2%의 회복률(回復率)을 보였다. 2. 계절적(季節的)으로 10월(月)에서 4월(月)까지가 연중최성기(年中最盛期)이나 5월(月)에서 9월(月)까지도 적지않은 환자(患者)의 발생(發生)을 볼 수 있었다. 3. 연령별분포(年齡別分布)를 보면 15세(歲)${\sim}29$세군(歲群)이 전체환자(全體患者)의 반이상(半以上)인 52.7%를 차지하고 있고 $0{\sim}14$세군(歲群)은 인구비(人口比)에 대해 발생(發生)이 훨씬 적은 결과(結果)를 보이고 있다. 4. 도착시간별(到着時間別) 입원율(入院率)은 오전(午前) 10시이후(時以後) 도착군(到着群)서부터는 입원율(入院率)이 급증(急增)하는데 이는 병원도착(病院到着)이 늦일수록 당일회복(當日回復)이 되지못하고 입원가료(入院加療)하게 됨을 나타내주는 결과(結果)라 할 수 있다. 5. 병발증(倂發症)으로는 급성욕창, 폐렴(肺炎) 및 신경학적(神經學的) 이상등(異常等)의 소견(所見)을 많이 볼 수 있었다.

• 한국환경과학회지
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• 제28권2호
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• pp.225-233
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• 2019

In this study, we investigated the in vitro anti-biofilm activities of plant extracts of chives (Allium tuberosum), garlic (Allium sativum), and radish (Raphanus sativus L.) against environment harmful bacteria (gram-positive Staphylococcus aureus and, gram-negative Salmonella typhimurium and Escherichia coli O157:H7). In the paper disc assay, garlic extracts exhibited the highest anti-biofilm activity. The Minimal Inhibitory Concentration (MIC) of all plant extracts was generally higher for gram-negative bacteria than it was for gram-positive bacteria. Gram-negative bacteria were more resistant to plant extracts. The tetrazolium dye (XTT) assay revealed that, each plant extract exhibited a different anti-biofilm activity at the MIC value depending on the pathogen involved. Among the plant extracts tested, garlic extracts (fresh juice and powder) effectively reduced the metabolic activity of the cells of food-poisoning bacteria in biofilms. These anti-biofilm activities were consistent with the results obtained through light microscopic observation. Though the garlic extract reduced biofilm formation for all pathogens tested, to elucidate whether this reduction was due to antimicrobial effects or anti-biofilm effects, we counted the colony forming units of pathogens in the presence of the garlic extract and a control antimicrobial drug. The garlic extract inhibited the E. coli O157:H7 biofilm effectively compared to the control antimicrobial drug ciprofloxacin; however, it did not inhibit S. aureus biofilm significantly compared to ciprofloxacin. In conclusion, garlic extracts could be used as natural food preservatives to prevent the growth of foodborne pathogens and elongater the shelf life of processed foods.