• Title/Summary/Keyword: CNKI

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한약을 이용한 chemotherapy-induced peripheral neuropathy (CIPN) 치료 관련 무작위 배정 임상 시험에 대한 고찰 (A review of herbal medicines for chemotherapy induced peripheral neuropathy)

  • 박봉기
    • 대한암한의학회지
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    • 제21권2호
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    • pp.51-61
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    • 2016
  • Background : Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect in cancer patients who were exposed to chemotherapy. CIPN impacts on the quality of life and could delay chemotherapy. The aim of this review was to assess the therapeutic effectiveness of herbal medicine in CIPN patients. Methods : Randomized controlled trials (RCTs) were included in this review. We searched MEDLINE, Cochrane database, EMBASE, CNKI, Wanfang and four Korean databases without restrictions on time or language. The risk of bias was assessed using the Cochrane risk of bias tool. Results : Eleven RCTs involving 706 patients met the inclusion criteria. Eleven different herbal medicines were examined in the included trials. Almost RCTs showed insufficiency in the reporting randomization method and allocation concealment. One trial used allocation concealment and a double-blinding method. Five studies reported that participants dropped out of RCTs and conducted an 'as-treated analysis'. One trials reported adverse effects of herbal medicine. In ten of the eleven trials, the use of herbal medicine had shown significant differences in clinical symptoms or nerve conduction velocity. Conclusions : The use of herbal medicines for CIPN showed significant improvements in the management of CIPN. However, conclusions cannot be drawn because of the generally low quality of methodology and low quantity of data for each single herbal medicine. Further rigorous trials are needed.

자폐 스펙트럼 장애에 대한 한국과 중국의 한방치료 연구 동향 비교 (A Comparison between Korean and Chinese Clinical Studies for the Treatment of Autism Spectrum Disorder)

  • 조연수;백정한
    • 대한한방소아과학회지
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    • 제32권2호
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    • pp.26-42
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    • 2018
  • Objectives The purpose of this study is to figure out the recent trend of the treatment for autism spectrum disorder (ASD) by comparing Korean and Chinese clinical studies. Methods National Digital Science Library (NDSL), Oriental medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS) and Korean Traditional Knowledge Portal (KTKP) were used to search Korean studies which were published from January, 2011 to May, 2017. Also Chinese National Knowledge Infrastructure (CNKI) and Wanfang data were used to search Chinese studies which were published from the same period. Key words of 'Autism' and 'Autism spectrum disorder' were used. Results 3 Korean studies and 21 Chinese studies were selected and analyzed to find out the most commonly used diagnostic criteria, treatments, including herbal medicine and acupuncture, and treatment assessment procedures. Conclusions As a result of comparing Korean and Chinese clinical studies for the treatment of ASD, both Korean and Chinese medicine treatments showed their effectiveness. However, there were some differences between two countries' clinical trends. In order for this study to be helpful, more highly evidenced clinical studies should be followed.

뇌성마비(Cerebral palsy) 소아의 재활치료와 재활과 침치료의 병행치료를 비교한 체계적 문헌 고찰 (The Effect of Acupuncture combined with Conventional Rehabilitation Treatment for Cerebral palsy: A Systematic review of Randomized Controlled Trials(RCTs))

  • 장석주;성은학;김장현;민상연
    • 대한한방소아과학회지
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    • 제34권3호
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    • pp.81-96
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    • 2020
  • Objectives This study aims to evaluate the effect of acupuncture combined with rehabilitation treatment for cerebral palsy in children. Methods 7 electro-database (PubMed, CENTRAL, CNKI, DBpia, KISS, OASIS, KJTK) were searched for using the keywords "cerebral palsy AND acupuncture" which study is designed in randomized controlled trials (RCTs). Results 10 out of 303 studies were included in analysis after screened. Acupuncture combined with rehabilitation treatment had a significant effect on motor function. Only 1 study reported minor adverse effects. Conclusions All of the studies have shown acupuncture combined with conventional rehabilitation treatment was effective in cerebral palsy. Additional well-designed studies are needed to justify the effectiveness of acupuncture in cerebral palsy.

뇌졸중 후 배뇨장애 침치료의 임상연구에 대한 고찰 (Review of Clinical Research on Acupuncture Treatment of Voiding Difficulty in Stroke Patients)

  • 박봉우;윤종민;문병순
    • 대한한방내과학회지
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    • 제36권2호
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    • pp.153-164
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    • 2015
  • Objectives: The aim of this study was to collect and analyze studies on acupuncture therapies for treatment of voiding difficulty in stroke patients and to suggest methods of study for acupuncture therapies. Methods: Electronic searches were performed on search sites including NDSL, 국회도서관, RISS4U, DBPIA, KISS, KMBASE, KoreaMed, 한국전통지식포탈, OASIS, Pubmed, CNKI, using the search words ‘중풍’, ‘뇌졸중’, ‘stroke’, ‘배뇨장애’, ‘voiding’, ‘urinary’, ‘incontinence’, ‘retention’, ‘ ’, ‘침치료’, and ‘acupuncture’ as single or combined keywords, from January 1990 to August 2013 with language limitation, Korean, English, Chinese. Also, quality of the studies were evaluated using Jadad score. Results: The searches identified 16 studies for selection and analysis. In the present study, voiding difficulty includes urinary incontinence and urinary retention. The acupuncture points CV4, SP6, and CV3 were the most frequently used. Treatments were most frequently applied daily. The times and terms of acupuncture treatment, were most frequently 30 minutes per treatment for 4 weeks Conclusions: The acupuncture therapies were effective in the treatment of voiding difficulty in stroke patients, but the study of acupuncture therapy as a treatment for this issue in stroke patients needs to be standardized and high-quality study models should be introduced.

비만증에 대한 부항요법의 중의학 임상연구 고찰 (Review of Clinical Studies for Obesity Using Cupping Therapy in Traditional Chinese Medicine)

  • 유정은;장새별
    • 한방비만학회지
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    • 제15권2호
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    • pp.137-143
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    • 2015
  • The purpose of this study is to investigate the clinical studies of cupping therapy for obesity in Traditional Chinese Medicine (TCM) and to evaluate the effects of it for use in practice. CNKI were searched for controlled studies on cupping therapy for obesity that were published up to September 2015. The review included 9 randomized controlled trials, and we analyzed the objectives, process of interventions, outcome measurements, and main results of the studies. We found that cupping therapy combined with acupuncture, electric acupuncture or thread embedding have more effectively decreased body mass index, waist circumference and lipid profile than acupuncture, electric acupuncture or thread embedding only have done. In the reviewed studies, cupping therapy treated in the region of abdomen, upper and lower limbs, and dorsal part operating on 5 to 25 minutes for one time with total 6 to 45 times of schedule. In this study, we demonstrated that cupping therapy combined with acupuncture, electric acupuncture or thread embedding could have effectively used for treating obesity. Further evaluation and clinical researches are required to establish evidence in practice.

진균성 질염의 한약 훈증 치료에 대한 체계적 문헌 고찰 (Systematic Review of Herbal Medicine Fumigation Treatment for Mycotic Vaginitis (Candida Vaginitis))

  • 박경덕;배주은;윤영진
    • 대한한방부인과학회지
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    • 제31권3호
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    • pp.20-32
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    • 2018
  • Objectives: The purpose of this study is to identify the effectiveness of fumigation treatment, provide a clinical basis for fumigation therapy, and develop treatment protocols through consideration of treatment methods and herbal medicines. Methods: We searched for randomized controlled clinical trials using fumigation treatment on mycotic vaginitis in 8 electronic databases such as EMBASE, Pubmed, and CNKI. The results of the studies were analyzed and the risk of bias was assessed by using Cochrane risk of bias tool. A meta-analysis was performed to reveal the effectiveness of fumigation compared to control treatments. Results: We finally selected 5 studies among 54 articles according to inclusion criteria and exclusion criteria. In all selected studies, herbal fumigation was more effective than any control treatment and all the studies were statistically significant. Conclusions: The study provides a basis for applying fumigation treatment to patients with mycotic vaginitis and helps developing a treatment protocol of caring patients of mycotic vaginitis. But the limitation of this study is that the number of studies included is small and quantitative synthesis of all results has not been achieved.

기능성 자궁출혈에 대한 한약치료 : 체계적 문헌 고찰 (Traditional Herbal Medicine for Dysfunctional Uterine Bleeding versus Western Medicine: A Systematic Review of Randomized Controlled Trials)

  • 박어진;조희근;최지현
    • 대한한방부인과학회지
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    • 제31권4호
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    • pp.110-127
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    • 2018
  • Objectives: To evaluate the effectiveness and safety of traditional herbal medicine (THM) in the treatment of dysfunctional uterine bleeding (DUB) versus conventional western medicine. Methods: Randomized Controlled Trials (RCTs) comparing THM vs. conventional western medicine for DUB, were obtained from PubMed, Cochrane Library, Embase, CNKI, RISS, NDSL, KISS and OASIS. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 16 RCTs with 1,659 patients were identified and reviewed. 10 RCTs reported THM was statistically effective than control group in effective rate. Also recurrent rate was estimated in 6 RCTs and was lower than control group. 7 studies observed adverse events (AEs) and severe AEs were not reported. Conclusions: Despite several limitations, this review suggested that THM was safe and effective in the treatment of DUB. THM may also decrease the recurrence rate. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more sternly designed trials are warranted.

아토피피부염의 침 치료 임상연구 동향 (Trend for Acupuncture treatment Clinical Trial on Atopic Dermatitis)

  • 박수연;최정화;정민영;이기현
    • 한방안이비인후피부과학회지
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    • 제33권1호
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    • pp.45-55
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    • 2020
  • Objectives : The objective of this study is to review the Trend of clinical trials conducted with the acupuncture treatment on Atopic Dermatitis. Methods : Through 4 foreign online databases(PubMed, Cochrane library, EMBASE, CNKI) and 3 domestic online databases(NDSL, RISS, OASIS), we searched for clinical studies performed acupuncture treatment for Atopic Dermatitis from 2010 to December 2019. Only randomized controlled trials(RCT) was selected and anlayzed according to the research method. Results : A total 4 studies were reviewed. LI11, ST36, SP10 were most frequently used acupoints in acupuncture treatment. Among the evaluation indexes, SCORAD, VAS, DLQI were used most. In most of the 4 studies, acupuncture treatment showed significant therapeutic effects. Conclusions : These results suggest that it is necessary to develop more detailed standards about Acupuncture treatment method as the method of acupuncture is getting more diverse, and objective tools are needed in evaluating Atopic Dermatitis.

여성 복압성 요실금에 대한 뜸 치료의 효과 : 체계적 문헌 고찰 (The Efficacy of Moxibustion for Female Stress Urinary Incontinence: a Systematic Review)

  • 박혜린;조희근
    • 대한한방부인과학회지
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    • 제33권4호
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    • pp.1-22
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    • 2020
  • Objectives: The purpose of this review is to evaluate the efficacy of moxibustion for stress urinary incontinence (SUI) in women. Methods: For relevant randomized controlled trials (RCTs), we searched the following databases from their inception to September 1, 2020: The Cochrane Library, PubMed, EMBASE, Chinese National Knowledge Infrastructure Database (CNKI), Koreanstudies Information Service System (KISS), Research Information Sharing Service (RISS), and National Digital Science Library (NDSL). The key search terms were 'stress urinary incontinence' and 'moxibustion'. Data extraction and assessment of risk of bias were conducted by two authors independently. Results: A total of 11 RCTs were finally included in this systematic review. In all studies, moxibustion treatment was applied as an adjuvant therapy to the conventional treatment, and the most common conventional treatment was pelvic floor muscle training (PFMT). The treatment group (conventional treatment plus moxibustion) showed statistically more significant effect than the control group (conventional treatment only) in various evaluation indicators including urinary incontinence frequency, 1 hour urine pad test, quality of life, the clinical efficacy rate, and pelvic muscle strength. Conclusions: In this study, we investigated the efficacy of moxibustion as an adjuvant therapy for female SUI patients. Further studies are needed to supplement the safety of moxibustion and the evaluation of moxibustion dose.

사암침법 간정격과 간승격의 최근 연구 동향 분석 (Recent Study Trends of the Liver-tonification and Liver-sedation of Saam Acupuncture)

  • 윤민지;김송이;박지연
    • Korean Journal of Acupuncture
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    • 제35권1호
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    • pp.1-17
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    • 2018
  • Objectives : This study was aimed to investigate current status researches and to provide source in setting development strategy on Liver-tonification acupuncture(LTA) and Liver-sedation acupuncture(LSA). Methods : We searched databases of Pubmed, KISS, OASIS, Google scholar and CNKI up to February 2017. We included articles that using LTA or LSA as main treatment, using the partial acupoints combination of LTA or LSA, or using each acupoint of LTA or LSA. We analyzed disease, details of acupuncture and control treatment and clinical outcomes from included studies. Results and Conclusions : Among the included clinical studies, case report was the most used methodology. LTA used to treat obesity, myopia, bartholinitis, tinnitus, hiccup and sleep disorder, prostate cancer and tremor. LSA used to treat panic disorder, gastroesophageal reflux disease and irritable bowl syndrome, herpes zoster and neuralgia. Obesity and tremor were the most studied diseases using LTA or LSA. Amyotrophic lateral sclerosis was the only disease which LTA or LSA have no therapeutic effect. Each acupoints was not used as a meaning of Saam acupuncture but as affiliated meridian acupoint. Since animal researches were not fully conducted, mechanism of LTA and LSA was hard to be proved. Thus, more clinical studies and basic animal research are needed.