• 제목/요약/키워드: CMT1A

검색결과 119건 처리시간 0.023초

전기전도도(電氣傳導度) 측정(測定)에 의한 유우(乳牛) 준임상형(準臨床型) 유방염(乳房炎)의 진단(診斷)에 관한 연구(硏究) 1. 전기전도도법(電氣傳導度法)과 간접검진법(間接檢診法)(CMT 및 총체세포수(總體細胞數))과의 비교(比較) (Studies on the Diagnosis of Subclinical Mastitis in Cows by the Measurement of the Electrical Conductivity: 1. Comparison of Various Methods of Handling Conductivity Data with the Use of California Mastitis Test and Direct Somatic Cell Count)

  • 강병규
    • 대한수의학회지
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    • 제24권1호
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    • pp.91-98
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    • 1984
  • A total of 466 foremilk from dairy farms in Chonnam district was examined for the subclinical mastitis over a period of one year, using a method of the electrical conductivities(EC); absolute conductivity(AC) and differential conductivity(DC) and quarter difference value(QD), in relation to the California mastitis test(CMT) and the direct somatic cell count(DSCC). The compatibility and efficiency rating between the EC values and the other screening tests was conducted. Obtained results are summarized as follows. 1. A linear relationship was found between the EC values and the CMT scores and direct somatic cell counts and it was found that electrical conductivity measurements were comparable with other screening tests for diagnosing animals with mastitis. 2. Compatibilities between the EC and CMT were 70.4% in AC, 74.6% in DC and 70.7% in QD, and that of the EC and DSCC were 53.0% in AC, 63.1% in DC and 53.2% in QD. On the other hand, relative efficiency ratings of Postle's equation between EC and CMT were 37.3% in AC, 26.5% in DC and 13.6% in QD, and that of the EC and DSCC were 33.1% in AC, 20.2% in DC and 11.9% in QD. 3. In the foremilk samples collected from damaged quarters determined by EC, the false positive rate wart higher than the false negative rate, and consequently tests of EC produced lower compatibility or efficiency rating scores. These tendencies suggested that any factors other than the mastitic condition influencing the EC values might be existed.

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소아 해수에 대한 추나요법의 효과: 체계적 문헌 고찰과 메타분석 (Chuna Manual Therapy for Pediatric Cough: A Systematic Review and Meta-analysis)

  • 박혜진;김현태;이상현;황만석;황의형;신병철;허인
    • 척추신경추나의학회지
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    • 제16권1호
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    • pp.25-34
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    • 2021
  • Objectives This review was conducted to evaluate the effectiveness and clinical significance of Chuna manual therapy (CMT) in the treatment of pediatric cough. Methods Ten electronic databases (PubMed, EMBASE, Cochrane, CNKI [CAJ], KMBASE, KISS, KISTI, NDSL, RISS, and Oasis) were searched. Only randomized controlled trials (RCTs) using CMT for pediatric cough treatment were included. The methodological quality of each RCT was evaluated using the Cochrane risk-of-bias tool (v1.0). Results Nine RCTs met the inclusion criteria. The meta-analysis revealed positive effects of CMT in the treatment of pediatric cough. Both CMT alone and CMT combined with Chinese medication or Chinese medicine acupoint application (CMAA) were effective in treating pediatric cough. Conclusions This systematic review shows the reliability, effectiveness, and clinical significance of CMT in the treatment of pediatric cough. However, the evidence is limited due to the defective design of the included RCTs. More well-designed RCTs are required to provide clearer evidence for this claim.

$(Ba_{1-x}Ca_x)(Mg_{1/3}Ta_{2/3})O_3$ 세라믹스의 구조와 유전특성 (Structure and Dielectric Properties of $(Ba_{1-x}Ca_x)(Mg_{1/3}Ta_{2/3})O_3$ Ceramics)

  • 조정호;조종래;김강언;정수태
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2000년도 영호남학술대회 논문집
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    • pp.167-170
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    • 2000
  • The structural changes and the dielectric properties of $(Ba_{1-x}Ca_x)(Mg_{1/3}Ta_{2/3})O_3$ (x=0, 0.2, 0.4, 0.6, 0.8, 1) were investigated. The densities of samples were gradually decreased with increasing x, (BMT=7.69, CMT=5.25 $g/cm^3$). The crystal structure of BMT was a untiltied perovskite structure, however BCMT showed antiphase tilting and antiphase-inphase tilting structure. The dielectric constant($\varepsilon_r$) of the highest value was 33 at x=0.2 (BMT=24, CMT=17). The maximum quality factor was 27,500GHz in BMT. The quality factor· of BCMT was decreased to x<0.2 (5,000GHz), and was gradually increased to x>0.2. The temperature coefficients of dielectric constant was positive at x<0.8, and negative in CMT.

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산후 유즙분비부전에 대한 추나 치료: 체계적 문헌 고찰 및 메타분석 (Chuna Manual Therapy for Postpartum Hypogalactia: A Systematic Review and Meta-Analysis)

  • 김채영;이은별;김현지;안희덕
    • 척추신경추나의학회지
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    • 제17권1호
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    • pp.1-10
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    • 2022
  • Objectives To evaluate the effectiveness of Chuna manual therapy (CMT) for postpartum hypogalactia. Methods Using nine electronic databases, we selected 13 randomized controlled trials (RCTs) that applied CMT for postpartum hypogalactia and conducted a meta-analysis. The risk of bias was assessed using the Cochrane risk of bias tool. Results Meta-analysis showed statistically significant results for CMT in terms of effective rate and breast filling degree compared to the other treatment groups (p<0.05). Conclusions Our study showed clinical evidence of CMT efficacy for postpartum hypogalactia. Further studies are required to support our findings.

전립선비대증에 대한 추나요법의 효과: 체계적 문헌 고찰 (Chuna Manual Therapy for Benign Prostatic Hyperplasia: A Systematic Review)

  • 전천후;박나리;이예지;조충식
    • 척추신경추나의학회지
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    • 제15권1호
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    • pp.65-74
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    • 2020
  • Objectives : This study aimed to evaluate the randomized controlled clinical trials (RCTs) analyzing the effectiveness of Chuna manual therapy (CMT) for benign prostatic hyperplasia (BPH). Methods : Among the literature published until May 2020, a literature search was carried out using 10 electronic databases using related keywords to identify all RCTs that applied CMT for the treatment of BPH. The Cochrane risk of bias tool was used to assess the methodological quality of each RCT. Results : Five RCTs met our inclusion criteria and were included in the analysis. These studies showed that CMT had no positive results compared to herbal medication. However, positive results were shown in terms of an increased efficacy rate, reduced international prostate symptom scores, and increased maximum flow rate when CMT was combined with acupuncture or herbal medication. Conclusions : Based on the analysis, this review has limited evidence of CMT being beneficial in the treatment of BPH. Therefore, further investigation is required using well-designed RCTs to support the effectiveness of CMT and to obtain higher evidence.

Age Group-Specific Improvement of Vertebral Scoliosis after the Surgical Release of Congenital Muscular Torticollis

  • Jong Min Choi;Seong Hoon Seol;Jae Hyun Kim;Chan Min Chung;Myong Chul Park
    • Archives of Plastic Surgery
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    • 제51권1호
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    • pp.72-79
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    • 2024
  • Background Congenital muscular torticollis (CMT) is a common musculoskeletal disorder in children. Secondary scoliosis can occur in patients with CMT; however, the extent of inclination and improvement of scoliosis after surgical correction of CMT have not been adequately studied. In this study, we aimed to evaluate and measure the improvement in vertebral tilting after surgical correction according to age at the time of surgery. Methods Between June 2007 and January 2020, 831 patients with CMT underwent sternocleidomastoid release. Among them, 426 patients were enrolled, and their medical records were retrospectively reviewed. Ultimately, 210 patients available for radiological evaluation and analysis were enrolled in this study. The patients were divided into four groups according to age at the time of surgery to determine the relationship between age and changes in scoliosis. Results Our findings showed an improvement in scoliosis in all age groups after surgery. The results for follow-up after 1 year confirmed long-term improvement in vertebral tilting. The degree of improvement in scoliosis was significantly higher in the younger age group than in patients aged 18 years or older. Conclusion The effect of surgical release on scoliosis was significant in all age groups. The findings of this study suggest that CMT should be corrected before the age of 3 years to ensure an optimal surgical mitigation of scoliosis. Furthermore, in cases of neglected CMT, surgical release should be actively attempted because there is significant improvement.

ANALYSIS OF GAS-DYNAMIC EFFECTS IN COMPACT EXHAUST SYSTEMS OF SMALL TWO-STROKE ENGINES

  • Galindo, J.;Serrano, J.R.;Climent, H.;Tiseira, A.
    • International Journal of Automotive Technology
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    • 제8권4호
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    • pp.403-411
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    • 2007
  • This article describes a methodology based on experiments and 1D modeling work related to the exhaust system analysis of a small two-stroke engine. The primary goal of this work was to understand how the design criteria of a compact exhaust system influenced the exhaust port pressure, since its evolution controls not only engine performance but also exhaust emissions. On the experimental side, a fully instrumented 50cc two-stroke engine was used to check the behavior of three different exhaust systems. A problem related to instantaneous pressure measurements in unsteady, hot flow was detected and solved during the study. To build the 1D model of the three exhaust systems, experimental information on the steady flow and the impulse test rigs was obtained under controlled conditions in specific facilities. Accurate comparisons between measured and calculated exhaust port instantaneous pressures were obtained from the following different exhaust system configurations: a straight duct, a tapered pipe and the three compact exhaust systems. The last step in the method used this model to analyze the pressure waves inside the exhaust system and detect the influence of the geometric parameters. The results should lead to improvements in the design process of complex compact exhaust systems in two-stroke engines.

만성 위염에 대한 추나요법의 효과: 체계적 문헌고찰 (Chuna Manual Therapy for Chronic gastritis : A Systematic Review)

  • 이남우;김기현;신병철
    • 척추신경추나의학회지
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    • 제12권2호
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    • pp.1-14
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    • 2017
  • Objectives: To systematically evaluate the effectiveness and safety of Chuna manual therapy (CMT) for chronic gastritis (CG). Methods: We searched twelve English, Chinese and Korean databases using relevant keywords up to September 2017. All randomized controlled trials (RCTs) of CMT for CG were considered for inclusion. The methodological quality of included RCTs was assessed by the Cochrane risk of bias tool. Results: Seven RCTs with 403 CG patients were included. The meta-analysis of 6 studies showed that CMT had statistically significant effects (p<0.0001) on effective rate for CG compared to conventional medication. Conclusions: This systematic review suggests that CMT seems effective for CG, but limited evidence from risk of bias. For future studies, high-quality RCTs such as sham-controlled studies with standardized interventions are needed to provide sufficient evidence on the effects of CMT for CG.

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총명탕(聰明湯)과 목근피총명탕(木槿皮聰明湯) 열수추출물, 초미세분말제형이 microglia 및 기억력 감퇴 병태모델에 미치는 영향 (Effects of ChongMyung-Tang and ChongMyung-Tang added Hibiscus syriacus Hot water extract & Ultra-fine Powder on Microglia and Memory Deficit Model)

  • 최강욱;이상룡;정인철
    • 동의생리병리학회지
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    • 제20권5호
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    • pp.1200-1210
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    • 2006
  • This experiment was designed to investigate the effect of the CMT and MCMT hot water extract & ultra-fine powder on microglia and memory deficit model. The effects of the CMT and MCMT hot water extract on expression of IL-l${\beta}$, IL-6, TNF-${\alpha}$, NOS-II, COX-2, IL-10, TGF-${\beta}$1 mRNA and production of IL-lP, IL-6, TNF-a, NO, ROS in BV2 microglial cell line treated by lipopolysacchaide(LPS) ; serum glucose, uric acid, AChE activity of the memory deficit mice induced by scopolamine , behavior of the memory deficit mice induced by scopolamine and were investigated, respectively. The CMT and MCMT hot water extract suppressed the expression of IL-1${\beta}$, IL-6, TNF-${\alpha}$, NOS-II, COX-2 mRNA, production of IL-l${\beta}$, IL-6, TNF-${\alpha}$, NO, ROS and increased the expression of IL-10, TGF-${\beta}$l mRNA in BV2 microglial cell line treated by LPS. The MCMT hot water extract & ultra-fine powder increased glucose, decreased uric acid and AChE significantly in the serum of the memory deficit mice induced by scopolamine. The CMT and MCMT hotwater extract & ultra-fine powder groups showed significantly inhibitory effect on the scopolamine-induced impairment of memory in the experiment of Morris water maze. According to the above result, it is suggested that the CMT and MCMT hot water extract & ultra-fine powder might be usefully applied for prevention and treatment of dementia.

A novel p.Leu699Pro mutation in MFN2 gene causes Charcot-Marie-Tooth disease type 2A

  • Kang, Sa-Yoon;Ko, Keun Hyuk;Oh, Jung-Hwan
    • Annals of Clinical Neurophysiology
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    • 제21권1호
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    • pp.57-60
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    • 2019
  • Axonal Charcot-Marie-Tooth disease (CMT2) has most frequently been associated with mutations in the MFN2 gene. MFN2 encodes mitofusin 2, which is a mitochondrial fusion protein that plays an essential role in mitochondrial function. We report CMT2 in a Korean father and his son that manifested with gait difficulties and progressive atrophy of the lower legs. Molecular analysis revealed a novel heterozygous c.2096T>C (p.Leu699Pro) mutation in the exon 18 of MFN2 in both subjects. We suggest that this novel mutation in MFN2 is probably a pathogenic mutation for CMT2.