• Title/Summary/Keyword: CHA

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Clinical Outcomes of Frozen-thawed Embryo Transfer after Microsurgical Removal of Damaged Blastomere (동결-융해 배아 이식에서 손상된 할구의 미세 수술적 제거의 임상적 효과)

  • Choi, Won Yun;Sohn, Jie Ohn;Park, Eun A;Lee, Dong Ryul;Lee, Woo Sik;Han, Se Yul;Park, Lee Suk;Cho, Jung Hyun;Kim, Soo Hee;Cha, Kwang Yul;Yoon, Tae Ki
    • Clinical and Experimental Reproductive Medicine
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    • v.32 no.1
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    • pp.55-64
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    • 2005
  • Objective: Human infertility clinics have been faced the demand for improving clinical results. The purpose of this study was to evaluate the effect of microsurgical removal of damaged blastomeres (DB) in frozen-thawed embryos on the clinical outcomes. Methods: From January 2003 to May 2004, out of 258 thawing ET cycles were divided into three groups: Group-1 (n=46): Intact cleavaged embryos after thawing. Remained cycles with embryos containing DB were randomly divided into two groups. Group-2 (n=102): Drilling zona pellucida (ZP) of frozen-thawed embryos by acidified Tyrode's solution. Group-3 (n=110): Drilling ZP and removal of DB. Embryos after microsurgical manipulation were transferred into the uterus of patients. Results: Clinical profiles and the mean number of transferred embryos among three groups were not different. Pregnancy and implantation rates were similar in three groups. It were 30.4% and 9.3% in Group-1, 29.4% and 7.8% in Group-2, and 26.4% and 7.6% in group-3, respectively. Miscarriage rate in Group-3 (37.9%) was slightly higher than those in Group-1 and Group-2 (14.3% and 23.3%), but it was not statistically significant. Conclusion: Intact cleaving embryos after DB removal showed higher potent of pregnancy and implantation. We could not find any improvement of clinical outcome by removal of DB in frozen-thawed embryos.

A Case of Catamenial Hemoptysis Treated by Bronchial Artery Embolization

  • Shin, Suk Pyo;Park, Chi Young;Song, Ji Hyun;Kim, Hong Min;Min, Daniel;Lee, Sang Hwan;Kang, San Ha;Jeon, Gyeong Sik;Lee, Ji-Hyun
    • Tuberculosis and Respiratory Diseases
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    • v.76 no.5
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    • pp.233-236
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    • 2014
  • Catamenial hemoptysis is a rare condition, characterized by recurrent hemoptysis associated with the presence of intrapulmonary or endobronchial endometrial tissue. Therapeutic strategies proposed for intrapulmonary endometriosis with catamenial hemoptysis consist of medical treatments and surgery. Bronchial artery embolization is a well-established modality in the management of massive or recurrent hemoptysis, but has seldom been used for the treatment of catamenial hemoptysis. We report a case of catamenial hemoptysis associated with pulmonary parenchymal endometriosis, which was successfully treated by a bronchial artery embolization.

Endobronchial ALK-Positive Anaplastic Large Cell Lymphoma Presenting Massive Hemoptysis

  • Kim, Hee Kyung;Kim, Bo Hye;Kim, Sae Ahm;Shin, Jae Kyoung;Song, Ji-Hyun;Kwon, Ah-Young;Kim, Jung-Hyun;Kim, Eun-Kyung;Lee, Ji-Hyun;Kim, Gwaung-Il;Jeong, Hye Cheol
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.4
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    • pp.390-395
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    • 2015
  • Primary anaplastic large cell lymphoma (ALCL) of the lung is highly aggressive and quite rare. We report here a case of anaplastic lymphoma kinase-positive endobronchial ALCL, that was initially thought to be primary lung cancer. A 68-year-old woman presented with hemoptysis, dyspnea, and upper respiratory symptoms persisting since 1 month. The hemoptysis and and bronchial obstruction lead to respiratory failure, prompting emergency radiotherapy and steroid treatment based on the probable diagnosis of lung cancer, although a biopsy did not confirm malignancy. Following treatment, her symptoms resolved completely. Chest computed tomography scan performed 8 months later showed increased and enlarged intra-abdominal lymph nodes, suggesting lymphoma. At that time, a lymph node biopsy was recommended, but the patient refused and was lost to follow up. Sixteen months later, the patient revisited the emergency department, complaining of persistent abdominal pain since several months. A laparoscopic intra-abdominal lymph node biopsy confirmed a diagnosis of ALCL.