• The Korea Journal of Herbology
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• v.27 no.4
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• pp.9-16
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• 2012

Objective : Canavalia gladiata DC semen (CGS) have been used to improve hematopoietic activity. In the current study, we investigated whether CGS regulate hemato-potentiating function using hematopoietic stem cells (HSCs) as a testing system. Methods : HSCs isolated from femur in mice with leukopenia and thrombocytopenia induced induced by CTX. Then, Real-time PCR was performed to measure the mRNA expression and hematopoietic related gene (EPO, IL-3, SCF, c-kit, GM-CSF), the phoaphorylation of GATA-1 and STAT-5a/b were observed by ELISA method, and the number of granulocyte erythrocyte monocyte macrophage colony-forming units (CFU-GEMM) and erythroid burst forming units (BFU-E), semisolid clonogenic assay was performed. Result : When HSCs were treated with CGS, the expression of hematopoietic related genes (EPO, IL-3, SCF, c-kit, and GM-CSF) were significantly increased at the levels of mRNA as well as production in HSCs. Additionally, CGS enhanced phosphorylation of STAT-1 and signal transducer and activator of transcription-5a/b (STAT-5a/b) in HSCs. Furthermore, CGS significantly enhanced the growth rate of granulocyte erythrocyte monocyte macrophage colony-forming units (CFU-GEMM) and erythroid burst forming units (BFU-E) in vitro. Conclusion : These result suggest that CGS has hematopoietic enhancement via hematopoietic cytokine-mediated GATA-1/STAT-5a/b pathway.

• Proceedings of the Ginseng society Conference
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• 1987.06a
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• pp.59-66
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• 1987

Psychotropic actions of crude ginseng saponins(CGS), pure ginsenoslue Rbl(GS-bl) and gin- senoside Rgl(GS-gl) isolated from the root of Panax ginseng, were evaluated by determining their effects on agonistic behavior in male(Experiment 1) and female(Experiment 2) mice, using a biologically relevant method. The results of experiment 1 demonstrated that CGS and GS-bl significantly suppressed aggressive episodes (offensive sideways posture and attack bite) in a dose-dependent manner when the resident was drugged, whereas G5-gl was ineffective. However, when the intruder was treated with one of three ginseng saponins, agonistic behavior between resident and intruder males was not altered. In experiment 2, acute administration of CGS and G5-bl significantly suppressed maternal aggression, whereas GS-gl was ineffective. As compared with the vehicle-treated group, chronic treatment with CGS and GS-bl significantly suppressed maternal aggression, while GS-gl showed a tendency to increase the frequency of attack bite by females. These findings clearly indicate that the root of Panax ginseng contains psychoactive ingredient, which can suppress both intermale and maternal aggression in mice. We suggest that the present results have important implications for the clinical usefulness of ginseng saponins in psychiatric medicine.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.61-73
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• 2021

Metaheuristic search methods have been developed to solve problems with a range of purpose functions in situations lacking information and time constraints. In this study, the Hybrid Vision Correction Algorithm (HVCA), which enhances the performance of the Vision Correction Algorithm (VCA), was developed. The HVCA has applied two methods to improve the performance of VCA. The first method changes the parameters required by the user for self-adaptive parameters. The second method, the CGS structure of the Exponential Bandwidth Harmony Search With a Centralized Global Search (EBHS-CGS), was added to the HVCA. The HVCA consists of two structures: CGS and VCA. To use the two structures, a method was applied to increase the probability of selecting the structure with the optimal value as it was performed. The optimization problem was applied to determine the performance of the HVCA, and the results were compared with Harmony Search (HS), Improved Harmony Search (IHS), and VCA. The HVCA improved the number of times to find the optimal value during 100 repetitions compared to HS, IHS, and VCA. Moreover, the HVCA reduced the Number of Function Evaluations (NFEs). Therefore, the performance of the HVCA has been improved.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.07a
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• pp.439-442
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• 2001

Chalcogenide glassy semiconductors(CGS) can be obtained by the melt quenching technique. We have investigated the thin film heterostructures : metal-chalcogenide glassy semiconductors, where metal is copper, and chalcogenide glassy semiconductors are glasses of the system As-Se. CU/CGS film heterostructure were produced in the vacuum evaporator by the method of vacuum thermal evaporation. Doped films are very sensitive to external actions, and this property allows developing supersensitive precision sensors of temperature, humidity, illumination, and etc. based on them. Cu/CGS film has shown that resistance strongly depend on the temperature. The ratio of resistance vs. temperature has shown over a 2 k$\Omega$/degree. The slop of temperature and resistance shows linear.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.07b
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• pp.727-730
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• 2002

Chalcogenide glassy semiconductors(CGS) can be obtained by the melt quenching technique. We have investigated the thin film heterostructures : metal-chalcogenide glassy semiconductors, where metal is copper, and chalcogenide glassy semiconductors are glasses of the system As-Se. Cu/CGS film heterostructure were produced in the vacuum evaporator by the method of vacuum thermal evaporation. Doped films are very sensitive to external actions, and this property allows developing supersensitive precision sensors of temperature, humidity, illumination, and etc. based on them. Cu/CGS film has shown that resistance strongly depend on the temperature. The slop of temperature and resistance shows linear.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.11 no.3
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• pp.281-291
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• 1999

A computer code based on a node equation method has been developed for the analysis of pipe network. Both data structure and object-oriented programming technique are used for pipe and node modelling, in which simplification process is applied to complicated and large pipe network. The semi-direct solver, ILU-CGS, improves greatly both the accuracy and the rate of convergence. The computational result of high-pressure pipe network of city gas in Taegu shows the good agreement with the real data.

• Journal of Korea Multimedia Society
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• v.11 no.11
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• pp.1592-1600
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• 2008

This study is to help creative idea generation based on the theory of the 'reconstruction of character shape image elements', and aims to extrusion of creative and diverse shapes with combination of image elements upon computing creative image generation. In order to suggest the design generation methodology for the maximization of idea generation ability and to overcome restriction of thinking out of existing idea generation methodology, it has suggested the CGS(Character Generation System) that is a creative idea generation methodology identified and complemented the problem of the existing computerized idea generation(PDS with Proportion) method out of the preceded studies on the creative idea generation methodologies. this study is expected to have effectives as one method for idea generation or creative image generation assistance during the 3D character development process, and to serve as an assistance to overcome the restriction of the character shape image generation through diverse idea generations.

• Structural Engineering and Mechanics
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• v.46 no.6
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• pp.791-808
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• 2013

The main purpose of this paper is to develop seismic fragility curves for existing reinforced concrete, RC, buildings based on the post earthquake field survey and the seismic performance using capacity design. Existing RC buildings constitute approximately 65% of the total stock in Algiers. This type of buildings, RC, was widely used in the past and chosen as the structural type for the future construction program of more than 2 millions apartments all over Algeria. These buildings, suffered moderate to extensive damage after the 2003 Boumerdes earthquake, on May 21st. The determination of analytical seismic fragility curves for low-rise and mid-rise existing RC buildings was carried out based on the consistent and complete post earthquake survey after that event. The information on the damaged existing RC buildings was investigated and evaluated by experts. Thirty four (34) communes (districts) of fifty seven (57), the most populated and affected by earthquake damage were considered in this study. Utilizing the field observed damage data and the Japanese Seismic Index Methodology, based on the capacity design method. Seismic fragility curves were developed for those buildings with a large number data in order to get a statistically significant sample size. According to the construction period and the code design, four types of existing RC buildings were considered. Buildings designed with pre-code (very poor structural behavior before 1955), Buildings designed with low code (poor structural behavior, between 1955-1981), buildings designed with medium code (moderate structural behavior, between 1981-1999) and buildings designed with high code (good structural behavior, after 1999).

• Earthquakes and Structures
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• v.12 no.4
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• pp.397-407
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• 2017

To estimate the structural seismic demand, some methods are based on an equivalent linear system such as the Capacity Spectrum Method, the N2 method and the Equivalent Linearization method. Another category, widely investigated, is based on displacement correction such as the Displacement Coefficient Method and the Coefficient Method. Its basic concept consists in converting the elastic linear displacement of an equivalent Single Degree of Freedom system (SDOF) into a corresponding inelastic displacement. It relies on adequate modifying or reduction coefficient such as the inelastic deformation ratio which is usually developed for systems with known ductility factors ($C_{\mu}$) and ($C_R$) for known yield-strength reduction factor. The present paper proposes a rational approach which estimates this inelastic deformation ratio for SDOF bilinear systems by rigorous nonlinear analysis. It proposes a new inelastic deformation ratio which unifies and combines both $C_{\mu}$ and $C_R$ effects. It is defined by the ratio between the inelastic and elastic maximum lateral displacement demands. Three options are investigated in order to express the inelastic response spectra in terms of: ductility demand, yield strength reduction factor, and inelastic deformation ratio which depends on the period, the post-to-preyield stiffness ratio, the yield strength and the peak ground acceleration. This new inelastic deformation ratio ($C_{\eta}$) is describes the response spectra and is related to the capacity curve (pushover curve): normalized yield strength coefficient (${\eta}$), post-to-preyield stiffness ratio (${\alpha}$), natural period (T), peak ductility factor (${\mu}$), and the yield strength reduction factor ($R_y$). For illustrative purposes, instantaneous ductility demand and yield strength reduction factor for a SDOF system subject to various recorded motions (El-Centro 1940 (N/S), Boumerdes: Algeria 2003). The method accuracy is investigated and compared to classical formulations, for various hysteretic models and values of the normalized yield strength coefficient (${\eta}$), post-to-preyield stiffness ratio (${\alpha}$), and natural period (T). Though the ductility demand and yield strength reduction factor differ greatly for some given T and ${\eta}$ ranges, they remain take close when ${\eta}>1$, whereas they are equal to 1 for periods $T{\geq}1s$.

• Proceedings of the IEEK Conference
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• 2008.06a
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• pp.75-76
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• 2008

A low complexity encoding scheme for coarse grain scalability is proposed. The proposed method exploits the statistics of residuals between current and reference blocks using the macroblock mode predicted from the previous quality layer. To test how the mode is optimal in the current layer, the statistical hypothesis testing for the variances of the residual sub-blocks is performed. The proposed method reduces the total encoding time up to 51% when three CGS scalability layers are encoded. However, the quality degradation and bit-rate increment of the each layer are negligible.