• Title/Summary/Keyword: CGE analysis

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Suppression of colon cancer by administration of Canavalia gladiata D.C. and Arctium lappa L., Redix extracts in tumor-bearing mice model (종양이식 생쥐모델에서 도두(刀豆), 우방근(牛蒡根) 추출물의 대장암 억제 효과)

  • Jang, Ji-Hye;Ji, Kon-Young;Choi, Hyung-Seok;Yang, Won-Kyung;Kim, Han-Young;Kim, Kun-hoae;Kang, Hyung-Sik;Lee, Young-Cheol;Kim, Seung-Hyung
    • The Korea Journal of Herbology
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    • v.32 no.5
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    • pp.27-38
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    • 2017
  • Objective : In the present study, we examined whether Canavalia gladiata D.C. (CG) and Arctium lappa L., Redix (AL) mixture (CGAL), their components, lupeol and chicoric acid, regulate immune system and suppress the tumor in vitro and in vivo. Methods : LPS-induced reactive oxygen species (ROS) and nitric oxide (NO) were measured after treatment with CG extract (CGE), CGAL, lupeol, chicoric acid and lupeol and chicoric acid mixture (lupeol+CA) in Raw264.7 cell. To determine the effect of CGE on immune responses, immune cell population and IgG production were assessed in mice. To investigate the effect of CGAL and their component on anti-tumor activity, tumor volume and weight were measured, cell cycles and immune cell population were analyzed in MC38 injected tumor bearing mice. Also, NK cell activity was determined in splenocyte isolated from tumor bearing mice. Results : CGE, CGAL, lupeol, chicoric acid and lupeol+CA decreased the LPS-induced ROS and NO production without cell toxicity in RAW264.7 cells. CGE increased the immune cell populations of $CD4^+T$, $CD8^+T$ and macrophages in various immune organ of mice. In tumor bearing mice, CGAL, lupeol, chicoric acid and lupeol+CA suppressed tumor volume and weight. In cell cycle analysis, they decreased the percentages of S phase. In addition, CGAL, lupeol, chicoric acid and lupeol+CA immune cell populations of $CD4^+T$, $CD8^+Tcell$, NK cell and macrophage in tumor as well as NK cell activity. Conclusion : CGAL and its compounds may enhance immune responses and suppress tumor growth, and may be capable of developing health functional foods.

The evaluation of aid effectiveness using the input-output analysis: the case of Vietnam (산업연관분석을 활용한 원조의 국가단위 효과 평가 - 한국 유상원조의 베트남 지원효과를 중심으로 -)

  • Park, Bokyeong;An, Jiyoun
    • International Area Studies Review
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    • v.22 no.2
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    • pp.211-218
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    • 2018
  • The evaluation of aid effectiveness at the national level has mostly focused on qualitative evaluation. This paper attempts to quantitatively evaluate EDCF 's support for Vietnam in 1995 ~ 2016 on the economy. First, we compare the strengths and weaknesses of various methodologies that can be used for quantitative assessment: panel analysis based on growth theory, input-output analysis, social account matrix analysis, CGE model, DSGE model, and time series analysis. Using the input-output analysis, we estimate that total output and value added have been generated about $5.9 billion and $1.7 billion in Vietnam, respectively. The increase in income per capita from the support was estimated to have contributed to a 0.21%p reduction in the poverty rate in Vietnam.

Post-TPP Trade Policy Options for ASEAN and its Dialogue Partners: "Preference Ordering" Using CGE Analysis

  • Ji, Xianbai;Rana, Pradumna B.;Chia, Wai-Mun;Li, Changtai
    • East Asian Economic Review
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    • v.22 no.2
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    • pp.177-215
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    • 2018
  • Trump's withdrawal from the Trans-Pacific Partnership (TPP) and his "America First" trade agenda ignite a second round of interest in mega-free trade agreements in the Asia-Pacific. Countries are evaluating alternative trade policy actions in a post-TPP era. Using national real GDP gains estimated by a modified GTAP model to construct "preference ordering" for 10 Association of Southeast Asian Nations members and their six regional dialogue partners, this paper comes up with several policy-oriented findings. First, when multilateral agreements are not possible, countries are better off with a regional trading agreement than without one. Second, the Regional Comprehensive Economic Partnership is likely to have higher beneficial impacts than the Comprehensive and Progressive Agreement for Trans-Pacific Partnership. Third, for dual-track countries, implementing both agreements is better than each separately. Fourth, impacts of open regionalism are likely to be higher than those of a closed and reciprocal one. Going forward, this paper argues that countries should adopt a "multi-track, multi-stage" approach to trade policy.

Canavalia gladiata regulates the immune responses of macrophages differently depending on the extraction method

  • Lee, Ha-Nul;Kim, Young-Min;Jang, Ah-Ra;Kim, Young Ran;Park, Jong-Hwan
    • Korean Journal of Food Science and Technology
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    • v.52 no.6
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    • pp.622-626
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    • 2020
  • Recent studies have suggested that Canavalia gladiate, a dietary food and traditional folk medicine, has promising pharmaceutical potential, but the effects have mostly been demonstrated using its organo-soluble extract. To date, its immunomodulatory effect depending on the extraction method is unclear. Here, the immune responses of macrophages to C. gladiate and the underlying mechanisms were studied. C. gladiate hot water extract (CGW) induced cytokine production in bone marrow-derived macrophages (BMDMs) in a dose-dependent manner, whereas its ethanolic extract (CGE) did not. Immunoblotting analysis also showed that CGW activated nuclear factor (NF)-κB and mitogen-activated protein kinases (MAPKs). Moreover, an inhibitor assay revealed the involvement of NF-κB, p38, and JNK, but not ERK, in CGW-induced cytokine production. CGE inhibited lipopolysaccharide-stimulated production of pro-inflammatory cytokines and activation of NF-κB and MAPKs in BMDMs. The results suggest that C. gladiate regulates the immune responses of macrophages differently depending on the extraction method.

Economic impact of digitalization on agriculture: a Korean perspective

  • Jung-Won Youm;Su-Hwan Myeong;Jeong-Ho Yoo
    • Korean Journal of Agricultural Science
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    • v.49 no.1
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    • pp.31-43
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    • 2022
  • The global trade environment is rapidly changing. The spread of COVID-19 promotes digitalization, and online transactions are becoming the new normal. Currently, Korea is actively introducing information and communication technology (ICT) that uses the internet of things (IoT) in relation to agriculture. However, few studies have analyzed the impact of digitalization on trade in the agricultural sector. Thus, the purpose of this study is to examine how the introduction of digital technology can affect the economy and trade of Korea. In this study, we estimate the impact of introducing digital technologies using the computable general equilibrium (CGE) model. The results of this analysis indicate that the GDP could increase by 3.82% to 10.53%. Also, agricultural production and trade according to the model will significantly increase to 8.67% and 5.72%, respectively, through a productivity increase from Blockchain, IoT, and artificial intelligence (AI) technologies, despite logistics inefficiencies. Although the effects of digitalization could be significant, farmers are still struggling to introduce digital technologies, stemming from the fact that government support systems are concentrated in only a few sub-sectors. In this regard, support in this area must be expanded and diversified according to the current environment of agriculture in Korea.

Research on the Influence of FTA between Korea and Japan on Tourism (한.일 FTA체결이 관광산업에 미치는 영향에 관한 연구)

  • Kim, Cheol-Won;Lee, Tae-Suk
    • Journal of Applied Tourism Food and Beverage Management and Research
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    • v.17 no.1
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    • pp.41-67
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    • 2006
  • The study is aimed to analyze the influence of FTA(Free Trade Agreement) between Korea and Japan on tourism and to suggest ways to increase tourists exchange between them by considering countermeasures of Korea's tourism based on the analysis and deriving political significance. The results of the study showed that the expected effects of FTA between Korea and Japan on tourism would overall be positive. There would be increases in employment and a higher rate of foreign-exchange earning, which plays a critical role in the cash flow. Therefore the government is required to prepare for several political measures as follows. First, ways to promote investment in tourism have to be established in a systematic way for FTA. Second, restructuring of tourism has to be considered seriously for tourism to be a high value-added industry after FTA. Third, the tourism information industry needs to be included in the tourism promotion act to promote e-tourism using information technology. In addition to this, an expansive cluster strategy needs to be developed, which relates tourism to other industries like culture and movies and to find ways to re-locate and re-educate manpower currently engaged in the tourism industry. Though the study investigated the influence of FTA on tourism through a practical analysis, it was restricted only to Korea. So the influence of FTA between Korea and Japan on the tourism of Japan should be included in further study. Furthermore, in subsequent studies the CGE(Computable General Equilibrium) model will be applied for objective analysis of the effects. Or measuring the ripple effect with multinational inter-industry relation table will be made for the study to make practical contributions to the development of government policy.

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Computable General Equilibrium Analysis of Energy Markets with Imperfect Competition and Scale Economy (불완전경쟁 및 규모의 경제가 에너지 산업에 미치는 영향)

  • Park, Chang Won;Kim, Gene Uhc
    • Environmental and Resource Economics Review
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    • v.11 no.2
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    • pp.291-319
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    • 2002
  • This Paper investigates imperfect competition and economy of scale on Korean energy markets based on computable general equilibrium model. Some industries like energy sector have exhibited that their economies have strong economies of scale and imperfect competition. Thus these industrial organization facts should be incorporated into CGE model. In our model, non-competitive markets are adopted and compare these results with convention perfect competition model.

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Analysis of Androgen Receptor Gene by Capillary Gel Eelectrophoresis (모세관 젤 전기영동을 이용한 안드로젠 수용체 유전자 분석)

  • Kim, Yong-Seong;Baek, Seung-Gwon;Gang, Chung-Mu;Gang, Dae-Cheon;Lee, Su-Man;Choe, Byeong-Ok;Jeong, Gi-Hwa;Choe, Gyu-Seong
    • Journal of the Korean Chemical Society
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    • v.50 no.1
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    • pp.37-45
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    • 2006
  • gel electrophoresis (CGE) with poly(ethylene oxide) has been applied to the measurement of CAG repeat number in Androgen receptor (AR) gene related to male infertility. Non-linear regression analysis was performed using the standard X174 RF/Hae III, 100bp step ladder DNA in order to investigate the exact number of CAG repeat. For 79 Korean infertile males and 89 controls, CAG repeats at exon 1 in AR gene was compared and analyzed by CGE. It turned out that CAG repeat numbers were 24.972.6 range, 17-29) for the infertile male, and 23.992.4 range, 18-29) for the control, respectively. P value (0.018) was less then 0.05, meaning that the result was statistically meaningful.

Macroeconomic Buffer Effects of Mega-FTA Formation: A CGE Analysis for Korea

  • Jung, Jae-Won;Kim, Tae-Hwang
    • Journal of Korea Trade
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    • v.23 no.3
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    • pp.118-137
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    • 2019
  • Purpose - As global trade disputes intensify and global trade uncertainty increases due to the prevailing trade protectionism all over the world, mega-FTAs such as the RCEP and CPTPP are suggested as strategic trade policy options for export-driven small open economies, such as Korea. This paper aims to provide a comprehensive analysis of Korea's mega-FTA participation and the induced implications for the Korean economy. Design/methodology - We use a multi-region, multi-sector global CGE model, and investigate the different effects of both the US-China and US-EU trade wars on the relative changes in GDP, welfare, and trade under different trade policy regimes; (i) Korea does not participate in any mega-FTA, (ii) Korea participates in the RCEP, and (iii) Korea participates in the CPTPP. Findings - We show, among others, that though industrial effects might be largely varied, the overall enlarging of free trade zones through multilateral mega-FTA participation may contribute significantly to the macroeconomic soundness and stability of Korea, even when global trade protectionism prevails. Under RCEP and CPTPP trade regimes, Korea's GDP may increase even when the global trade environment deteriorates as trade wars occur and intensify between the US and China, or between the US and EU. It is also estimated that RCEP participation increases Korea's GDP, welfare (measured in equivalent variation), and total trade by 1.12%, $1.09 billion, and 2.54%, respectively, while CPTPP participation increases them by 0.19%, $0.92 billion, and 0.13%, respectively. Originality/value - Existing studies usually focus on the direct impacts of mega-FTA participation on macroeconomic variables such as GDP, welfare, and trade, and do not consider the possible buffer effects of a mega-FTA when the global trade environment worsens. In this paper, we analyze and quantify not only the direct impacts of RCEP and CPTPP on the main macroeconomic variables but also the possible buffer effects of the RCEP and CPTPP in the cases of the US-China and US-EU trade wars.

The Economic and Environmental Impact of the Small Hydropower Development in Korea: A CGE Analysis (소수력 발전 확대의 경제.환경적 효과: 연산일반균형모형 분석)

  • Kim, Jae-Joon;Park, Sung-Je
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.106-106
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    • 2011
  • 소수력은 온실가스 배출량이 적은 친환경 청정에너지원이면서 지역의 분산전원에 기여할 수 있는 유용한 자원으로 평가되고 있다. 이러한 여건은 소수력발전 사업이 전력의 smart grid 구축 효과로 인해 가장 큰 효율성을 달성할 수 있을 것으로 기대된다. 국내 소수력발전은 1500Mw의 부존량을 가진 것으로 평가되고 있으나 계절적 편중으로 인한 가동률 부족, 경제성 부족 등으로 활발한 보급이 이루어지지 않고 있다. 특히 신재생에너지 확대 전략에도 불구하고 지원금 등 경제적 인센티브 부족으로 인해 민간부문의 참여는 상당히 저조하다. 그럼에도 불구하고 수력에너지는 환경친화적이고 잠재성이 큰 신재생에너지로 온실가스 저감과 에너지 확보에 기여할 수 있다. 특히 수력에너지는 민간투자의 어려움이 존재하므로 정부의 장기적인 기술개발투자 및 효율성 확대 정책이 중요하다. 본 연구에서는 소수력 확대의 경제 환경적 효과를 평가해보기 위해 연산일반균형모형 (CGE :Computable General Equilibrium Model)을 구축한다. 본 연구는 다음과 같이 수행되었다. 첫째, 수력발전부문과 수도사업을 구분하고 사회회계행렬을 작성하였으며, 전력부문에서 수력발전을 포함한 다단계 생산구조를 가정하였다. 둘째, 일반균형모형 방정식 체계를 작성하고 모형의 파라미터 추정 등 보정(Calibration) 작업을 수행하였다. 셋째, 국가 중기 온실가스저감 시나리오를 적용한 전망을 수행하고 소수력 확대(투자지원) 시나리오를 구축한다. 본 연구는 저감수단으로 탄소세를 부과하였다. 끝으로, 소수력 발전 보급 확대의 경제적, 환경적 파급효과를 계산하였다. 분석결과, 소수력 발전 잠재 성장을 반영한 수력에너지 비중은 약 2020년에 약 4.5% 까지 증가하는 것으로 나타났다. 이로 인한 온실가스 저감 기여분은 약 3%에 이르는 것으로 계산 되었다. 또한 수도사업과 비에너지 제조업의 산업비중은 증가하였다. 이러한 결과는 소수력 발전 확대가 화석연료 대체를 통한 지속가능한 에너지 수요에 기여하고 지역개발과 물산업 발전 등 경제적 파급효과 등을 유발할 수 있음을 시사한다. 또한 본 연구에서 고려하지 못한 소수력 기술 개발은 에너지 대체 촉진으로 인한 온실가스 저감과 녹색성장에 기여할 것이다.

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