• Journal of the Korea Society of Computer and Information
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• v.16 no.11
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• pp.103-111
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• 2011

In this paper, we propose a Geometrical Centroid Contour Distance(GCCD) which is described by shape signature based on contour sequence. The proposed method uses geomertrical relation features instead of the absolute angle based features after it was normalized and aligned with dominant feature of the shape. Experimental result with MPEG-7 CE-Shape-1 Data Set reveals that our method has low time/spatial complexity and scale/rotation robustness than the other methods, showing that the precision of our method is more accurate than the conventional desctiptors. However, performance of the GCCD is limited with concave and complex shaped objects.

• Journal of Haehwa Medicine
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• v.16 no.2
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• pp.251-265
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• 2007

Yanhyeoljeseuptang(YHJST) is a traditional herbal medicine used for the treatment of dermatitis. The aim of this study was to confirm whether or not YHJST has a preventive effect on development of atopic dermatitis in dinitrochlorobenzene(DNCB)-applied Nc/Nga mouse. This study was undertaken to develop a reliable mouse model demonstrating similar immunologic phenomena as human atopic dermatitis characterized with predominance of type-2 immune response. NC/Nga mouse were sensitized with $200\;{\mu\ell}$ of 1% 2,4-dinitrochlorobenzene(DNCB) (acetone : olive oil = 3 : 1 mixture) and challenged twice or three times with $150\;{\mu\ell}$ of 0.2% DNCB in a week for the following 4 weeks. YHJST was administered orally to Nc/Nga mouse for 8 weeks, which led to the remarkable suppression on the development of dermatitis, as determined by various immune factors related to pathogenesis of atopic dermatitis in splenocytes and DLN cells. In this study, YHJST selectively suppressed T ce11 (CD4+, CD3+/CD69+, CD4+/CD25+) activation, which may be essential for ratio of IL-4 versus INF-$\gamma$ produced in the splenic T cell culture supernatants was approximately 3-fold higher in the mouse treated with DNCB than their control mouse respectively. Immunologic studies showed down-regulated that the capacity of spleen T cells to produce IL-4, but IFN-$\gamma$ was up-regulated by means of oral intake of these YHJST. These results strongly suggest that YHJST is a promising candidate for treatment of human atopic dermatitis.

• Journal of Haehwa Medicine
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• v.16 no.2
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• pp.267-280
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• 2007

Gupoongjeseuptang(GPJST) is a traditional herbal medicine used for the treatment of dermatitis. The aim of this study was to confirm whether or not GPJST has a preventive effect on development of atopic dermatitis in dinitrochlorobenzene(DNCB)-applied Nc/Nga mouse. This study was undertaken to develop a reliable mouse model demonstrating similar immunologic phenomena as human atopic dermatitis characterized with predominance of type-2 immune response. NC/Nga mouse were sensitized with $200\;{\mu\ell}$ of 1% 2,4-dinitrochlorobenzene(DNCB) (acetone : olive oil = 3 : 1 mixture) and challenged twice or three times with $150\;{\mu\ell}$ of 0.2% DNCB in a week for the following 4 weeks. GPJST was administered orally to Nc/Nga mouse for 6 weeks, which led to the remarkable suppression on the development of dermatitis, as determined by various immune factors related to pathogenesis of atopic dermatitis in splenocytes and DLN cells. In this study, GPJST selectively suppressed T ce11 (CD4+, CD3+CD69+, CD4+CD25+) activation, which may be essential for ratio of IL-4 versus INF-$\gamma$ produced in the splenic T cell culture supernatants was approximately 3-fold higher in the mouse treated with DNCB than their control mouse respectively. Immunologic studies showed down-regulated that the capacity of spleen T cells to produce IL-4, but IFN-$\gamma$ was up-regulated by means of oral intake of these GPJST. These results strongly suggest that GPJST is a promising candidate for treatment of human atopic dermatitis.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.253-257
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• 2010

최근 들어 이상 강우 현상으로 인한 기록적인 집중 강우와 더불어 토지 이용 변화로 인해 탁수의 발생 빈도가 증가하고 있다. 강우 유출로 유입한 탁수는 저수지 내 장기간 체류하면서 하류 하천의 수질 및 수생태계 뿐만 아니라 저수지 내부의 영양단계에도 많은 영향을 준다. 특히, 성층화된 저수지의 경우 높은 영양염류 농도를 포함한 탁수는 밀도류 거동 특성을 보이면서 수평 및 수직 혼합 과정을 거치면서 국부적인 부영양화 현상과 조류의 수화 현상의 원인이 되고 있다. 따라서 대형 저수지의 수질관리에 있어 하천 유입 탁수의 밀도류 해석, 저수지의 수온 성층 구조 변화, 부유입자의 동력학적 해석이 중요한 요소로 부각되어 왔다. 본 연구에서는 소양호를 연구 대상 지역으로 선정하여 2005년과 2007년 수문 사상을 바탕으로 2차원 횡방향 수치 모형을 구축하였다. 수치모형을 통해 수온 성층 구조의 재현성을 확인하였으며, 다양한 탁수 거동 모형을 구축하여 적용성을 평가하였다. 유입수의 SS(Suspended Solid)를 단일 입경으로 가정한 TM-1 모형, SS의 입경분포에 따라 3개의 그룹(SSi)으로 구분한 TM-2 모형, 3개 그룹을 포함하면서 저수지내 탁수 장기화로 인한 탁수 저감 효과를 1차 반응상수로 매개 변수화(유기물 함량($a_0$) ${\times}$ 분해속도(${\lambda}_a$))하여 수정된 지배방정식을 적용한 TM-3 모형을 사용하였다. 각각의 탁수 거동 모형은 2005년과 2007년 수문 조건에서 수온 성층 구조를 잘 재현하였다. TM-1 모형과 TM-2 모형을 비교해보면, 탁수 중심축의 최고 탁도에 대한 예측 성능은 TM-2 모형이 우수한 결과를 나타냈었다. 하지만, 장기 탁수 모의 시 저수지 수중 잔류 SS가 지속적으로 높게 나타나 중층 탁도를 과대평가하는 경향을 보였다. TM-3 모형이 TM-2 모형에 비해 수심별 탁도 분포에 대한 중심축 탁도가 저평가되는 경향을 보였지만 저수지 내 잔류 탁도에 대한 영향 부분에서는 개선된 결과를 나타내었다. 본 연구 결과는 저수지 탁수 밀도류 해석 및 운영 시스템에 활용 될 수 있으며, 선택 취수 설비 등의 수리 구조물의 영향 평가에 활용할 수 있다.

• Molecules and Cells
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• v.39 no.4
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• pp.330-336
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• 2016

Long non-coding RNAs (lncRNAs) are involved in multiple cellular events, as well as in tumorigenesis. Colon cance-rassociated transcript-1 (CCAT1) gene encodes an lncRNA whose over-activation was observed in an expanding list of primary human solid tumors and tumor cell lines, however its biological roles in acute myeloid leukaemia (AML) has not been reported yet at present. In this study, the aberrant upregulation of CCAT1 was detected in French-American-British M4 and M5 subtypes of adult AML patients. By gain- and loss-of-function analysis, we determined that CCAT1 repressed monocytic differentiation and promoted cell growth of HL-60 by sequestering tumor suppressive miR-155. Accordingly, a significant decrease in miR-155 level was detected in AML patients. Reintroduction of miR-155 into HL-60 cells restored monocytic maturation and repressed cell proliferation. Furthermore, CCAT1 could up-regulated c-Myc via its competing endogenous RNA (ceRNA) activity on miR-155. In conclusion, these results revealed new mechanism of lncRNA CCAT1 in AML development, and suggested that the manipulation of CCAT1 expression could serve as a potential strategy in AML therapy.

• Journal of Hydrogen and New Energy
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• v.23 no.5
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• pp.437-447
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• 2012

Ceria ($CeO_2$) was used to scavenge free radicals which attack the membrane in the polymer electrolyte membrane water electrolysis (PEMWE) circumstance and to increase the duration of the membrane. In order to improve the electrochemical, mechanical and electrocatalytic characteristics, engineering plastic of the sulfonated polyether ether ketone (SPEEK) as polymer matrix was prepared in the sulfonation reaction of polyether ether ketone (PEEK) and the organic-inorganic blended composite membranes were prepared by sol-gel casting method with loading the highly dispersed ceria and cesium-substituted tungstophosphoric acid (Cs-TPA) with cross-linking agent contents of 0.01 mL. In conclusion, CL-SPEEK/Cs-TPA/ceria (1%) membrane showed the optimum results such as 0.130 S/cm of proton conductivity at $80^{\circ}C$, 2.324 meq./g-dry-membrane of ion exchange capacity and mechanical characteristics, and 65.03 MPa of tensile strength which were better than Nafion 117 membrane.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.1
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• pp.27.1-27.1
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• 2011

We obtained the spectra of 93 Planet host stars and 73 normal field stars in F, G, K type using BOES at BOAO. We measured the equivalent width of Fe and 25 elements lines using the automatic EW measurement program, TAME(Tools for Automatic Measurement of Equivalent-widths) and estimated the elemental abundances by synth and abfind driver of MOOG code. Since the absence of planets in the normal field stars cannot be "completely" proved, this work focused on the chemical abundances and planet properties of planet host stars, which have the massive planets close to the parent star relatively. We carried out an investigation for the difference of abundances between stars with "Hot Jupiter" and normal field stars with no known planets. We examined the chemical composition of 25 elements, such as C, N, O, S, Na, Mg, Al, Si, K, Ca, Sc, Ti, V, Cr, Mn, Co, Ni, Cu, Zn, Sr, Y, Zr, Ba, Ce, Nd, and Eu by EW measurements, and the S abundances were estimated using synthetic spectrum. We have found that [Mg/Fe] and [Al/Fe] for planet host stars have lower limit comparing with those of comparison stars, and [Ca/Fe] of host star with Neptunian planets is relatively lower than the other host stars with massive planets. We have performed the Kolmogorov-Smirnov test, and examined the ratio of planet host stars to all stars for each bin of [X/H]. As a result, we noted that the O, Si, and Ca abfor undances are strongly related with the presence of planets.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.11A
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• pp.844-851
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• 2009

Handover is needed in multi-hop relay systems to support mobility. The main purpose of handover is to provide the continuous connection when a MS migrates from the air-interface of one BS to another air-interface provided by another BS. Especially the handover between different systems is essential to next generation network. Vertical Handover technology in Mobile WiMAX MMR system is very useful for operators to introduce to Mobile WiMAX system in an overlaid cell environment. This technology will be applied to technology which hands MRS(Mobile Relay Station) over to different systems for system performance enhancement in Ubiquitous environment overlaid between Micro ce11(Frequency 1,FA1) and Macro cell(Frequency 2,FA2). In this paper, FA1 and FA2 are used in order to perform Vertical Handover of MRS(Mobile Relay Station) according to suggested conditions. interferences from neighboring BS or other sectors of 6 macro cells surrounding center Macro cell are analyzed and throughputs are measured according to suggested conditions.

• Journal of the Korean Ceramic Society
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• v.48 no.5
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• pp.479-484
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• 2011

In this paper, investigations of thick film $La_{0.75}Sr_{0.25}Ga_{0.8}Mg_{0.16}Fe_{0.04}O_{3-{\delta}}$ (LSGMF) cells fabricated via spin coating on either NiO-YSZ anode or $La_{0.7}Sr_{0.3}Ga_{0.6}Fe_{0.4}O_3$ (LSGF) cathode substrates are presented. A La-doped $CeO_2$ (LDC) layer is inserted between NiO-YSZ and LSGMF in order to prevent reactions from occurring during co-firing. For the LSGF cathode-supported cell, no interlayer was required because the components of the cathode are the same as those of LSGMF with the exception of Mg. An LSGMF electrolyte slurry was deposited homogeneously on the porous supports via spin coating. The current-voltage characteristics of the anode and cathode supported LSGMF cells at temperatures between $700^{\circ}C$ and $850^{\circ}C$ are described. The LSGF cathode supported cell demonstrates a theoretical OCV and a power density of ~420 mW $cm^2$ at $800^{\circ}C$, whereas the NiO-YSZ anode supported cell with the LDC interlayer demonstrates a maximum power density of ~350 mW $cm^2$ at $800^{\circ}C$, which decreased more rapidly than the cathode supported cell despite the presence of the LDC interlayer. Potential causes of the degradation at temperatures over $700^{\circ}C$ are also discussed.

• Journal of the Korean Ceramic Society
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• v.53 no.5
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• pp.494-499
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• 2016

In this work, the effects of different sintering inhibitors added to $La_{0.8}Sr_{0.2}MnO_{3-{\partial}}$ (LSM) were studied to obtain an optimum cathode material for cathode-supported type of Solid oxide fuel cell (SOFC) in terms of phase stability, mechanical strength, electric conductivity and porosity. Four different sintering inhibitors of $Al_2O_3$, $CeO_2$, NiO and gadolinium doped ceria (GDC) were mixed with LSM powder, sintered at $1300^{\circ}C$ and then they were evaluated. The phase stability, sintering behavior, electrical conductivity, mechanical strength and microstructure were evaluated in order to assess the performance of the mixture powder as cathode support material. It has been found that the addition of $Al_2O_3$ undesirably decreased the electrical conductivity of LSM; other sintering inhibitors, however, showed sufficient levels of electrical conductivity. GDC and NiO addition showed a promising increase in mechanical strength of the LSM material, which is one of the basic requirements in cathode-supported designs of fuel cells. However, NiO showed a high reactivity with LSM during high temperature ($1300^{\circ}C$) sintering. So, this study concluded that GDC is a potential candidate for use as a sintering inhibitor for high temperature sintering of cathode materials.