• Title/Summary/Keyword: CE

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Benefit of Using Early Contrast-Enhanced 2D T2-Weighted Fluid-Attenuated Inversion Recovery Image to Detect Leptomeningeal Metastasis in Lung-Cancer Staging

  • Kim, Han Joon;Lee, Jungbin;Lee, A Leum;Lee, Jae-Wook;Kim, Chan-Kyu;Kim, Jung Youn;Park, Sung-Tae;Chang, Kee-Hyun
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.1
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    • pp.32-42
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    • 2022
  • Purpose: To evaluate the clinical benefit of 2D contrast-enhanced T2 fluid-attenuated inversion recovery (CE-T2 FLAIR) image for detecting leptomeningeal metastasis (LM) in the brain metastasis work-up for lung cancer. Materials and Methods: From June 2017 to July 2019, we collected all consecutive patients with lung cancer who underwent brain magnetic resonance image (MRI), including contrast-enhanced 3D fast spin echo T1 black-blood image (CE-T1WI) and CE-T2 FLAIR; we recruited clinico-radiologically suspected LM cases. Two independent readers analyzed the images for LM in three sessions: CE-T1WI, CE-T2 FLAIR, and their combination. Results: We recruited 526 patients with suspected lung cancer who underwent brain MRI; of these, we excluded 77 (insufficient image protocol, unclear pathology, different contrast media, poor image quality). Of the 449 patients, 34 were clinico-radiologically suspected to have LM; among them, 23 were diagnosed with true LM. The calculated detection performance of CE-T1WI, CE-T2 FLAIR, and combined analysis obtained from the 34 suspected LM were highest in the combined analysis (AUC: 0.80, 0.82, and 0.89, respectively). The inter-observer agreement was also the highest in the combined analysis (0.68, 0.72, and 0.86, respectively). In quantitative analyses, CNR of CE-T2 FLAIR was significantly higher than that of CE-T1WI (Wilcoxon signed rank test, P < 0.05). Conclusion: Adding CE-T2 FLAIR might provide better detection for LM in the brain-metastasis screening for lung cancer.

Hypoglycemic Effect of Chlorella sp. CMS-1 Hot Water Extract on Streptozotocin-Induced Diabetic Rats (Streptozotocin-유발 당뇨쥐에 대한 클로렐라 열수 추출물의 혈당 강하 효과)

  • Kim, Jung-Wook;Cha, Jae-Young;Heo, Jin-Sun;Jin, Hyun-Jin;Cho, Young-Su
    • Journal of Life Science
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    • v.18 no.11
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    • pp.1584-1591
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    • 2008
  • The effect of Chlorella hot water extract (CE) on hyperglycemia in streptozotocin- induced diabetic rats has not been studied. Therefore, hypoglycemic effect of CE in type I streptozotocin- induced diabetic rats was studied. Rats were fed a semisynthetic diet supplemented with either 3% (the STZ+CE3) and 6% (the STZ+CE6) CE or no supplement the Normal and the STZ-Control rats for 4 weeks. The concentrations of fasting and non-fasting blood glucose were higher in the STZ-Control rats than in the Normal rats, but this rise was lowered in the STZ+CE3 and the STZ+CE6 rats. Serum insulin concentrations were decreased with STZ injection, however, the decreased levels were almost restored to the Normal level with CE supplementation. The increased serum fructosamine levels associated with hyperglycemia were decreased with the CE treatment. The morphology of pancreatic islets in the Normal rat was round and maintained a typical arrangement. The STZ-Control pancreatic beta-cells were found to have significant swelling and severely morphological damaged, however, pancreatic tissue damage by STZ in the CE-supplemented diet group was ameliorated. This study shows that Chlorella hot water extract had a hypoglycemic effect on the STZ-diabetic rats via either increased insulin secretion during recovery or the prevention of STZ-induced pancreatic damage.

Microstructural property and catalytic activity of nano-sized MnOx-CeO2/TiO2 for NH3-SCR (선택적 촉매 환원법 재료로서 나노 사이즈 MnOx-CeO2/TiO2 촉매에 대한 미세 구조적 특성과 촉매활성 평가)

  • Hwang, Sungchul;Jo, Seung-hyeon;Shin, Min-Chul;Cha, Jinseon;Lee, Inwon;Park, Hyun;Lee, Heesoo
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.26 no.3
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    • pp.115-120
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    • 2016
  • $CeO_2$ is used as a co-catalyst with $TiO_2$ to improve the catalytic activity of $MnO_x$ and characterization of nano-sized powder is identified with de-NOx efficiency. A comparison between $MnO_x-CeO_2/TiO_2$ and single $CeO_2$ was conducted in terms of microstructural analysis to observe the behavior of $CeO_2$ in the ternary catalyst. The $MnO_x-CeO_2/TiO_2$ catalyst was synthesized by sol-gel method and the average particle size of the single $CeO_2$ is about $285{\mu}m$ due to the low thermal stability, whereas the particle size $MnO_x-CeO_2/TiO_2$ is about 130 nm. The strong interaction between Ce and Ti was identified through the EDS mapping by transmission electron microscopy (TEM). The improvement about 20 % of $de-NO_x$ efficiency is observed in the low-temperature ($150^{\circ}C{\sim}250^{\circ}C$) and vigorous oxygen exchange by well-dispersed $CeO_2$ is the reason of catalytic activity improvement.

Preparation of CeO$_2$ Thin Films as an Insulation Layer and Electrical Properties of Pt/$SrBi_2$$Ta_2$$O_9$/$CeO_24/Si MFISFET (절연층인 CeO$_2$박막의 제조 및 Pt/$SrBi_2$$Ta_2$$O_9$/$CeO_24/Si MFISFET 구조의 전기적 특성)

  • Park, Sang-Sik
    • Korean Journal of Materials Research
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    • v.10 no.12
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    • pp.807-811
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    • 2000
  • CeO$_2$ and SrBi$_2$Ta$_2$O$_{9}$ (SBT) thin films for MFISFET (Metal-ferroelectric-insulator-semiconductor-field effect transistor) were deposited by r.f. sputtering and pulsed laser ablation method, respectively. The effects of sputtering gas ratio(Ar:O$_2$) during deposition for CeO$_2$ films were investigated. The CeO$_2$ thin films deposited on Si(100) substrate at $600^{\circ}C$ exhibited (200) preferred orientation. The preferred orientation, Brain size and surface roughness of films decreased with increasing oxygen to argon gas ratio. The films deposited under the condition of Ar:O$_2$= 1 : 1 showed the best C- V characteristics. The leakage current of films showed the order of 10$^{-7}$ ~10$^{-8}$ A at 100kV/cm. The SBT thin films on CeO$_2$/Si substrate showed dense microstructure of polycrystalline phase. From the C-V characteristics of MFIS structure with SBT film annealed at 80$0^{\circ}C$, the memory window width was 0.9V at 5V The leakage current density of Pt/SBT/CeO$_2$/Si structure annealed at 80$0^{\circ}C$ was 4$\times$10$^{-7}$ /$\textrm{cm}^2$ at 5V.

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Adsorption Properties of U, Th, Ce and Eu by Myogi Bentonite Occurring in Japan (일본 묘기광산 벤토나이트의 물리화학적 성질 및 U, Th, Ce 및 Eu 흡착특성)

  • Song Min-Sub;Koh Sang-Mo;Kim Won-Sa
    • Journal of the Mineralogical Society of Korea
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    • v.18 no.3 s.45
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    • pp.183-194
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    • 2005
  • The mineralogical, physicochemical and thermal properties of the Myogi bentonite occurring in Japan were measured. A adsorption properties of U, Th, Ce and Eu ions on the Myogi bentonite were also investigated in different solution concentrations and pH conditions. The Myogi bentonite showed a strong alkaline character (pH 10.4), very high swelling, viscosity property and CEC, and a slow flocculation behavior due to the strong hydrophilic property. By the thermal analysis, the dehydroxylation of crystal water in bulk and clay fractions of the Myogi bentonite occur at $591^{\circ}C$ and $658^{\circ}C$, respectively, The adsorption experiments of ions such as U, Th, Ce and Eu were conducted for 0.2 g bentonites with 20mL solutions of various concentrations and different pH conditions with pH 3, 5, 7, 9, and 11. As a result, the Myogi bentonite showed excellent adsorption capacities for Ce, Th and Eu ions, whereas U ion showed very low adsorption capacity. Generally, Ce, Th and Eu ions showed the similar adsorption properties for the different concentrated solutions and pH conditions. These adsorption properties seem to be affected by the formation of various forms of chemical species and precipitation as well as ionic exchange reaction and surface adsorptions on smectite. Some associated zeolite minerals perhaps have some effects on the adsorption of U, Th, Ce and Eu on Myogi bentonite.

A Initial Channel Estimation Method Based on Extensive Preamble Utilization in MB-OFDM UWB System (프리엠블 확장 사용 기반 MB-OFDM UWB용 채널 추정 방식)

  • Jeong, Jin-Doo;Jin, Yong-Sun;Chong, Jong-Wha
    • 전자공학회논문지 IE
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    • v.48 no.1
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    • pp.30-35
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    • 2011
  • In this paper, we propose a method to improve the performance of initial channel estimation (CE) for the multiband-OFDM (MB-OFDM) UWB. The performance of the initial CE can be generally improved as increasing the number of the used preamble symbols. The MB-OFDM specification presents two CE symbols per band in preamble format. The performance of CE estimation with two CE symbols may be satisfied in relatively high sensitivity -77.5 and -72.5 dBm for 200 Mbps and 480 Mbps data rate, respectively, but can not be enough in the degraded 55 Mbps and 110 Mbps sensitivities such as -83.5 and -80.5 dBm, respectively. A method proposed in this paper achieves the performance improvement by extending CE estimation region to packet synchronization (PS) symbols and frame synchronization (FS) symbols including two CE symbols. This can improve the CE performance in the degraded SNR and increase the link-margin by reducing the error rate in physical-layer header. The link-margin improvement obtained by the proposed CE preamble can induce the decrease of error-rate in physical-layer header and increase of communication throughput. Simulation results for the proposed initial method show that the performance is improved by about 0.7 dB at 10-4 bit-error-rate using '4' symbols than initial method using only two CE symbols.

Capillary Electrophoretic Method for the Determination of (+)-Catechin, (-)-Epicatechin in Grape Seed Ethanol Extract (포도종실 에탄올 추출물에 함유된 (+)-카테킨, (-)-에피카테킨의 모세관 전기영동법에 의한 분석)

  • Choi, One-Kyun;Chung, Yang-Seop;Chung, Ha-Yull
    • Korean Journal of Food Science and Technology
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    • v.37 no.4
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    • pp.513-518
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    • 2005
  • Capillary electrophoresis (CE) method was developed to determine (+)-catechin and (-)-epicatechin contents in grape seed ethanol extract. CE separation was achieved using 100 mM phosphate and borate buffer at pH 6.0 as background electrolyte and fused silica capillary with 50 microns x 375 microns O.D. (effective length 20.0cm) maintained at $25^{\circ}C$. The applied voltage was 10kV, and detection was performed by DAD at 210 nm, Two catechins were well separated within 6 min with repeatability of <0.8% RSD for migration time and <2.0% RSD for peak area, and correlation coefficients higher than 0.994 were obtained from 58.0 to 174.0 mg/L with detection limit of 0.035 mg/L. Separated compounds were successfully determined. CE method was easy to handle and showed good reproducibility. CE method was compared with conventional coloring and HPLC methods, and main advantages of CE method were low amount of sample required, simple pre-sample treatment, good recovery rate, and short analysis time.

Reaction Characteristics of Cu/CeO2 Catalysts for CO Oxidation (일산화탄소 산화반응을 위한 Cu/CeO2 촉매의 반응특성)

  • Kim, Su Bin;Kim, Min Su;Kim, Se Won;Hong, Sung Chang
    • Applied Chemistry for Engineering
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    • v.30 no.5
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    • pp.620-626
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    • 2019
  • In this study, the effects of the structural properties of the catalyst on CO oxidation reaction by controlling the $Cu/CeO_2$ catalyst amount and calcination temperature were studied, and also the CO conversion rate of the catalyst at the temperature range of $100{\sim}300^{\circ}C$ was evaluated. XRD, Raman, BET, $H_2-TPR$, and XPS analyses were performed to confirm the effect of changes in the structural properties on the chemical properties of the catalyst. The result confirmed that a substitution bond between Cu and Ce was formed and a lot of Cu and Ce bonds were formed when the catalyst carrying 5 wt.%. Of Cu was calcined at $400^{\circ}C$. The Cu-Ce binding was confirmed by peak shifts in Raman analysis and also peaks appeared in $H_2-TPR$. In addition, the balance state analysis demonstrated that a lot of surface labile oxygen molecules are formed, which can be more easily contributed to the reaction with $Ce^{3+}$ species known to form a substitution bond easily. It was found that CO conversion rate of the catalyst used in this study was close to 100% at $150^{\circ}C$.

Cloning and DNA Sequence of Carboxymethylcellulase (CMCase) Gene from Cellulomonas sp. YE-5

  • Her, Song;Kim, Dong-Seob;Choi, Sun-Jin
    • Journal of Microbiology and Biotechnology
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    • v.3 no.2
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    • pp.86-90
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    • 1993
  • CMCase positive clones were screened from Cellulomonas sp. YE-5 and named pCE1, pCE2 and pCE3. Among the positive clones pCE1 was used for this study, because it has the smallest insert and the highest CMCase activity among the 3 clones, and its nucleotide sequence was determined. The CMCase gene in pCE1 was composed of 1071 bp of nucleotides coding 357 amino acids. Computer analysis showed that the pCE1 has 65% sequence homology with the endoglucanase from Cellulomonas fimi.

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Development of Embedded System Based on Windows CE 5.0 (S3C2410A와 Windows CE 5.0 기반의 임베디드시스템 개발에 관한 연구)

  • Kim, Do-Kyu
    • The Journal of Information Technology
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    • v.8 no.4
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    • pp.91-102
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    • 2005
  • In this paper, development of embedded system based on Windows CE 5.0 which released recently is studied. Embedded softwares for the target board using S3C2410A SOC based on ARM920T core are composed of (1) BSP(Board Support Package) contains an OAL(OEM Adaptation Layer) which includes a boot loader for initializing and customizing target hardware, device drivers, and a corresponding set of configuration files (2) Windows CE 5.0 kernel (3) SDK and MP3 test application. Particularly, PB(Platform Builder) provides the efficient functions to build, test and debug the BSP and CE kernel. It is looked forward to being widely spread that Windows CE 5.0 will be utilized at smart devices such as PMP, CNS and DMB phone which inevitably require a display device.

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