• Title/Summary/Keyword: CD99

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Vaccum Coating Synthesis and Characterization of the CdSe Nanostructures as a Semiconductor (화합물 반도체 CdSe 나노구조의 진공 코팅합성과 특성)

  • Chang, Ki-Seog;Hwang, Chang-Su;Park, Young-Heon
    • Korean Journal of Crystallography
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    • v.15 no.1
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    • pp.18-23
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    • 2004
  • In order to find the optical properties of CdSe thin film and CdSe nanostructure, the following experiments were performed: the CdSe wurtzite nanostructure was made by using 99.99% CdSe (Aldrich) powder with the $SiO_x$ substrates and the $AlO_x$ membranes in $7{\times}10^{-6}$ torr vacuum. (The average vacuum coating speed being 1 ${\AA}$/sec). The calculations obtained were about 200 nm diameter of nanotubes on the $AlO_x$ membranes and a crystallite size of about 2 nm on the $SiO_x$ substrates. These results were verified through the Scanning Electron Microscopy (SEM) analysis, thin film X-ray diffraction analysis and emission spectroscopy.

Radioimmunoimaging with Mixed Monoclonal Antibodies of Nude Mice Bearing Human Lung Adenocarcinoma Xenografts

  • Duan, Dong;Li, Shao-Lin;Zhu, Yu-Quan;Zhang, Tao;Lei, Cheng-Ming;Cheng, Xiang-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4255-4261
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    • 2012
  • The present study was conducted to evaluate radioimmunoimaging (RII) and in vivo distribution of mixed antibodies $^{99m}Tc$-EGFR-mAb and $^{99m}Tc$-CD44-mAb in nude mice bearing human lung adenocarcinoma xenografts. Single and mixed applications of the two radiolabeled monoclonal antibodies (mAbs) were compared. Direct labeling of $^{99m}Tc$ was applied to radiolabel the EGFR and CD44 mAbs. The properties of the radiolabeled antibodies were then characterized. RII and assessment of the distribution of the antibodies in nude mice bearing lung adenocarcinoma xenografts were achieved by applying separate and combined doses of $^{99m}Tc$-EGFR-mAb and $^{99m}Tc$-CD44-mAb. The labeling rates of $^{99m}Tc$ for EGFR-mAb and CD44-mAb were $91.5%{\pm}3.8%$ and $92.3%{\pm}4.1%$ respectively, with specific activities of 2.8 and $2.9MBq/{\mu}g$, respectively, and radiochemical purities (RCP) of 96.5% and 96.2%. The radioactivity uptake of the combined application of both radiolabeled antibodies was clearly higher than with a single application of either alone. The relative values of target-to-nontarget (T/NT) measured through the regional interest (ROI) technique were $5.59{\pm}0.42$ (mixed antibodies), $2.78{\pm}0.20$ ($^{99m}Tc$-EGFR-mAb), and $2.28{\pm}0.16$ ($^{99m}Tc$-CD44-mAb) in the RII. The body distribution of the radiolabeled antibodies and their imaging results were basically identical. Application of the mixed antibodies with $^{99m}Tc$-EGFR-mAb and $^{99m}Tc$-CD44-mAb can increase the radioactivity uptake of tumor tissue, leading to more ideal target-to-nontarget ratios, and therefore superior results.

Structural and Optical Characteristics of ZnS/CdS Powders and Thin Films (ZnS/CdS 분말과 박막의 구조 및 광학적 특성)

  • Chang, Ki-Seog
    • Journal of the Korea Institute of Military Science and Technology
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    • v.13 no.4
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    • pp.659-664
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    • 2010
  • The ZnS/CdS thin films were made using 99.99% ZnS and CdS(Aldrich) powders in $7{\times}10^{-6}torr$. The ZnS layer was coated over the CdS layer on an AlOx membrane within a vacuum, at the average speed of $1{\AA}/sec$. After studying the ZnS/CdS and CdS thin films(both with the dimensions of 2.52nm), using fluorescence spectroscopy and comparing the respective results together, we found that although both of the resulting spectra peaked at 390nm, the ZnS/CdS thin films showed a narrower peak, and a higher intensity of photoluminescence than the CdS thin films. The particles of ZnS/CdS thin films also proved to be more homogeneous in size. In addition, the ZnS layer acted as a protective layer. Also, after studying the spectra of ZnS/CdS thin films taken 30 days after their preparation, we found no signs of aging. These results were verified through the scanning electron microscopy(SEM), EDX analysis, thin film X-ray diffraction, and luminescence spectroscopy.

CD-ROM드라이브의 내부 소음원 탐지를 위한 전달특성 연구

  • 이동욱;차성운
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2004.05a
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    • pp.99-99
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    • 2004
  • CD-ROM에서 생성되는 소음은 구조소음과 공력소음의 분포비율을 생각해 볼 때 하드디스크 등의 경우와는 다소 다른 특성이 있는데, 구조적으로 차폐나 디스크의 크기 및 회전속도 등의 차이로 인해 공력소음의 비중이 매우 커진 점을 들 수 있다. 공기역학적으로 생성되는 소음은 구조소음의 경우와는 다르게 에너지 분포가 주기성을 찾아보기 어려우며 널은 주파수 대역에 고루 분포하는 특징이 있다.(중략)

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Removal of Heavy Metals from Acid Mine Drainage using AFMR Process (AFMR 공정을 이용한 광산폐수의 중금속 제거)

  • Paik, Byeong Cheon;Kim, Gwangbok
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.2
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    • pp.313-321
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    • 2000
  • This research is to remove heavy metals from AMD(Acid Mine Drainage) using AFMR(Anaerobic Floating Media Reactor) process. Two AFMR were operated at HRT(hydraulic retention time) of 3 days. COD/sulfate ratio from 0.3 to 0.8, temperature from $30^{\circ}C$ to $35^{\circ}C$, and alkalinity of 1.000mg/l(as $CaCO_3$). At COD/sulfate($SO{_4}^{2-}$) ratio of 0.5 and temperature of $35^{\circ}C$, the ratio of reduced sulfate($SO{_4}^{2-}$)/removed COD(mg/mg) kept about 1 and the reactor achieved 99.99% of Cr, Pb anee Fe, 98% of Cd, and 90% of Mn removal efficiencies, respectively. Decreasing temperature to $30^{\circ}C$ increased the ratio of reduced sulfate($SO{_4}^{2-}$)/removed COD(mg/mg) to 1.37. Amount of sulfate reduction maximized at the temperature of $30^{\circ}C$ and the COD/sulfate ratio of 0.4 in the influent and then removal efficiencies of heavy metals were 99.99% of Fe, 99.99% of Pb, 99,99% of Cr, 97.3% of Mn, 99.9% of Zn, 99.9% of Cd and 99.9% of Cu.

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CD44 and CD133 as Cancer Stem Cell Markers for Gastric Cancer

  • Lee, Hyun-Joo;Choi, Young-Sil;Kim, Sung-Joo;Moon, Hyoun-Jong
    • Journal of Gastric Cancer
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    • v.10 no.3
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    • pp.99-105
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    • 2010
  • Purpose: Currently, the two most influential gastric stem cell marker candidates are CD44 and CD133. The aim of this study was to make a comparison and determine the appropriate marker for use in gastric cancer stem cell research. Materials and Methods: We analyzed the expressions of CD44, CD133, and CD24 from the gastric cancer cell lines MKN45, MKN74, KATO-III, NCI-N87, SNU-1, SNU-216, SNU-601, SNU-638, and SNU-688 using flow cytometry. In addition, we measured the change in viability after applying 5 fluorouracil (5-FU) to the MKN45, MKN74, KATO-III, and NCI-N87 cell lines using a Cell Counting Kit 8. Results: CD133 expression was above moderate in the KATO-III, SNU-216, SNU-601 cell lines, whereas it was below 1% in the remaining cell lines. CD44 was expressed at levels above 5% in all gastric cancer cell lines. The effect of 5-FU on viability and CD133 or CD44 expression in the cell lines were not related. Conclusions: Expression of CD133 positive cells was insufficient in the gastric cancer cell lines. Therefore, of the cell lines tested, CD44 was the most appropriate tumor maker for research on gastric cancer stem cells.

Neutron Activation Analysis of Cadmium Deposition in Hair and Animal Tissues (동물체모 및 장기 중 카드뮴의 방사화 분석)

  • Ryu, Yong-Wun;Lee, Kee-Ho
    • Journal of Radiation Protection and Research
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    • v.15 no.2
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    • pp.17-25
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    • 1990
  • Rats were ingested in drinking water 600mg/L of cadmium chloride solution during 3 months, then the distribution of Cd in major organs and hair were determined by neutron activation analysis. The results were as followings. 1. After administration for 24 hours using $^{115m}Cd$ as tracer, the distribution of blood was 0.03%, kidney 2.99% and liver 3.50% to determine with whole body counter. 2. Cd metal was rapidly excreted with kidney through blood and their accumulation appeared in liver and hair. 3. The comparative data to determine using neutron activation analysis. the content of cadmium of major organs in rats ingested of $CdCl_2$ during 3 month were shown to increase significantly both hair and liver. Above facts, hair samples were able to use as the diagnostic index to evaluate the accumulation of cadmium in liver.

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Study on Adsorption and Recovery of Heavy Metal Ions, Cd(II) and Pb(II), by Chitin (키틴에 의한 중금속 Cd(II), Pb(II)이온의 흡착 및 회수에 관한 연구)

  • Kim, Eun-Kyung;Cho, Young-Koo;Kwon, Young-Du;Park, Mi-A;Kim, Han-Soo;Park, Kwang-Ha
    • Analytical Science and Technology
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    • v.15 no.2
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    • pp.163-171
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    • 2002
  • The adsorption characteristics of Cd(II) and Pb(II) ions has been studied by using chitin as an adsorbent. The pure chitin was obtained from the extraction of red-crab shell dumped by fish factory. Adsorption kinetics of Cd(II) and Pb(II) ions on the chitin reached at the maximum adsorption within two minutes. Adsorbed amounts of heavy metals were pH 7.0>10.5>3.5 in the following order. Adsorption ratio by chitin was 21${\sim}$99% for Cd(II) ion and 24${\sim}$95% for Pb(II) ion. Recovery ratio of Cd(II) ion on the chitin was 22${\sim}$53%, and that of Pb(II) ion was 22${\sim}$73%. The adsorption behavior of these heavy metals was explained well by Freundlich adsorption isotherm.

Growth of $Cd_{1-x}Zn_xS $ Thin films Using Hot Wall Epitaxy Method and Their Photoconductive Characteristics (HWE에 의한 $Cd_{1-x}Zn_xS $박막의 성장과 광전도 특성)

  • 홍광준;유상하
    • Korean Journal of Crystallography
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    • v.9 no.1
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    • pp.53-63
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    • 1998
  • The Cd1-xZnxS thin films were grown on the Si(100) wafers by a hot wall epitaxy method (HWE). the source and substrate temperature are 600℃ and 440℃, respectively. The crystalline structure of epilayers was investigated by double crystal X-ray diffraction (DCXD). Hall effect on the sample was measured by the van der Pauw method and the carrier density and mobility dependence of Hall characteristics on temperature was also studied. In order to explore the applicability as a photoconductive cell, we measured the sensitivity (γ), the ratio of photocurrent to darkcurrent (pc/dc), maximum allowable power dissipation (MAPD), spectral response and response time. The results indicated that the best photoconductive characteristic were observed in the Cd0.53Zn0.47S samples annealed in Cu vapor comparing with in Cd, Se, air and vacuum vapour. Then we obtained the sensitivity of 0.99, the value of pc/dc of 1.65 × 107, the MAPD of 338mW, and the rise and decay time of 9.7 ms and 9.3 ms, respectively.

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