• Title/Summary/Keyword: CCR7

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A Study on the Relative Efficiency and Productivity Change of IT Firms received Policy Fund (정책자금 받은 IT 기업의 상대적 효율성 및 생산성 변화 연구)

  • Kang, Ho-Jung;Jeon, In-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.3
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    • pp.677-683
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    • 2009
  • This study measures the relative efficiency and productivity change of IT firms received policy fund using DEA model and Malmquist Index for 2006-2007. The main results of this study can by summarized as follows. First, in case of efficiency of CCR for 2006-2007, the number of efficient firms(CCR value is one) are six firms, six firms, respectively. Second, in case of efficiency of BCC for 2006-2007, the number of efficient firms(BCC value is one) are eleven firms, thirteen firms respectively. Third, In case of return to scale for 2006-2007, DRS are fifteen firms and fourteen firms respectively. IRS are two firms and one firm respectively. DRS firms can improve efficiency by the reduction of scale and IRS Firms can improve efficiency by the increase of scale. Fourth, Mean value of Malmquist Index representing productivity change for 2006-2007 are bigger than 1.00. This imply that productivity increase was achieved.

A Study on Eco-efficiency in power plants using DEA Analysis (DEA 모형을 이용한 발전회사 환경효율성에 대한 연구)

  • Han, Jung-Hee
    • Journal of Digital Convergence
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    • v.11 no.5
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    • pp.119-133
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    • 2013
  • This study aims to provide power generating plants with eco-efficiency information. To implement the purposes, of study, both DEA(Data, Envelopment Analysis) model and interview were incorporated in terms of methodologies. To analyze the managerial efficiency, total labor cost and number of employees were considered as input factors. CO2, NOx, and water also were considered as input factors to analyze eco-efficiency. Both annual total power product and annual total revenue were used as output factors. CRS(Constant Return to Scale) and VRS(Variable Return to) model were facilitated in this analysis. According to the findings, most of the power plants were evaluated as 'Efficient'' taking into consideration of average value, both 0.928 from CCR model and 0.969 from VRS model. 7 DMUs including DMU3 and DMU12 are efficient out of 35 DMUs relatively, other DMUs are inefficient. For results of inefficient output factors distribution, it was found that inefficiency for NOx was marked relatively higher than CO2. In order to improve the eco-efficiency in the power plants in the long term, the target amount of Co2 as well as NOx reduction needs to be properly proposed in consideration of particularity of power plants. In the long run, renewable energy, alternative fuels should be adapted to reduce the eco-inefficient.

Analyzing the Efficiency of Defense Basic Research Projects using DEA (자료포락분석(DEA)을 활용한 국방 기초연구개발 사업의 효율성 분석)

  • Lim, Yong-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.7
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    • pp.517-524
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    • 2020
  • In line with the recent wave of the 4th Industrial Revolution, the environment for defense R&D is transforming into a center of high-tech military technology. In particular, developed countries are strengthening control of technology exports and technology transfer to protect advanced defense science and technology. For this reason, the budget demand for securing the ability to develop independently high-tech weapons and core technologies suitable for the future battlefield environment is increasing, and increasing efficiency in R&D investment has been highlighted for efficient distribution of limited budgets. This study examined the efficiency of the defense basic R&D project using the non-parametric approach, DEA. The R&D budget, R&D researcher, and R&D period were selected as the input variables, and the number of papers and patents were used as output variables. The efficiency of basic R&D projects was analyzed through CCR, BCC models, and SE. Lastly, based on the efficiency measurements, the cause of the inefficiency of R&D projects was suggested, and ways to improve efficiency were suggested. This study is expected to be used as useful information that can be applied to project performance management through efficiency analysis of basic defense R&D projects and be reflected in the project planning stage through feedback.

Supplementation of Indigenous Green Microalga (Parachlorella sp.) to Pre-starter Diet for Broiler Chickens (초기 육계 사료내 토착미세조류(Parachlorella sp.) 첨가에 따른 성장 및 면역반응 변화)

  • An, Su Hyun;Joo, Sang Seok;Lee, Hyo Gun;Kim, Z-Hun;Lee, Chang Soo;Kim, Myunghoo;Kong, Changsu
    • Korean Journal of Poultry Science
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    • v.47 no.1
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    • pp.49-59
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    • 2020
  • The present study determined the effect of dietary cultivated microalgae (Parachlorella sp.) on the growth and immune responses of pre-starter broilers. A total of 320 one-day-old birds (Ross 308) were allocated to 4 treatments with 8 blocks in a randomized complete block design. The four experimental diets consisted of a corn-soybean meal-based control diet, and three diets contained 0.5%, 1.0%, and 1.5% microalgae powder at the expense of cornstarch in the control diet. After feeding the experimental diets for 7 days, the body weight and feed intake of all birds were measured, and 8 birds were randomly selected from each treatment. Peripheral blood mononuclear cells (PBMCs) and serum were harvested for immune profile assessment, including cytokines and cell migration receptors. No differences in growth performance were observed among the treatments. The birds that were fed diets containing graded levels of microalga showed a linear increase in the mRNA expression of cytokine genes in PBMCs, including that of IL2, IL1β, and IL18 (P<0.05). With respect to the chemokine receptor genes in PBMCs, mRNA expression of CCR2, CCR9, and ITGA4 changed quadratically (P<0.05), but that of CCR7 increased linearly (P<0.01). Cytokine protein secretion in blood, including that of IL-1β and IL-6, increased linearly (P<0.01) with an increase in the microalgal content. Overall, the present results show that the indigenous microalgae powder used in this study could stimulate immunity with no detrimental effects on the growth performance of pre-starter broiler chickens.

A Brief Efficiency and Clustering Measurement Way of Containerport by Using the Game Cross-efficiency Model (게임교차효율성모형을 이용한 컨테이너항만의 효율성 및 클러스터링 측정방법 소고)

  • Park, Rokyung
    • Journal of Korea Port Economic Association
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    • v.30 no.4
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    • pp.151-168
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    • 2014
  • The purpose of this paper is to show the brief efficiency and clustering measurement way by using the game cross-efficiency model which is newly introduced in this paper for 13 container ports during 3 years(2009, 2010, and 2013) with 3 input variables(depth, total area, and number of crane) and 1 output variable(container TEU). The main empirical results are as follows. First, the average rankings of game cross-efficiency model are Ningbo, Hongkong, Shanghai, Dubai, Singapore, Qingdao, Kaosiung, Busan, Tokyo, Incheon, Nagoya, Manila, Gwangyang ports in order. Second, according to ANOVA analysis, three models show the similar results in terms of the efficiency rankings. Third, in the clustering analysis using dendrogram, group A(Shangahi and Busan), group B(Ningbo and Nagoya), and group C(Incheon and Manila) show the common clustering ports during 3 or 2 years. The policy implication of this paper is that Korean port policy planner should introduce the game cross-efficiency method when measuring the individual port efficiency. Also port authority should consider the merits of the clustering ports for improving the port management and operations.

A Comparative Study of the Efficiency among Korea, Chinese, and Japanese Ports (한·중·일 항만효율성 비교연구)

  • KOO, Jong-soon;LEE, Jung-sun;JEON, Dong-hwa
    • The Journal of shipping and logistics
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    • v.27 no.3
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    • pp.457-474
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    • 2011
  • The aim of this study is to analyze the efficiency of major ports in Northeast Asia such as Korea, China and Japan. For the empirical analysis, we tried to apply the data envelopment analysis (DEA), which is an efficiency evaluation model based on mathematical programming theory, and we also established a model to Northeast Asian ports. In our opinion, DEA analysis which involves multiple inputs as well as multiple outputs in its efficiency valuation makes analysis more suitable for port efficiency measurement because ports produce a number of different outputs. In this paper, we attempted to analyze the relative efficiency of 27 ports (5 Korean ports, 13 Chinese ports, 9 Japanese ports) through DEA-CCR, DEA-BCC models. According to the result, Chinese ports are relatively efficient than Korean and Japanese ports. The result of the analysis shows that 7 Chinese ports are efficient in DEA-CCR model in 2009, but in DEA-BCC model 8 Chinese ports and 1 Koran port are efficient. Most of inefficient ports have a value closed to 1 in efficiency for scale, it means that the reason of inefficiency is caused from the technical aspect. Furthermore, we also verified that there exists excess of input in Korean and Japanese ports than Chinese ports.

The Mitochondrial Fusion-Related Proteins Mfn2 and OPA1 are Transcriptionally Induced during Differentiation of Bone Marrow Progenitors to Immature Dendritic Cells

  • Ryu, Seung-Wook;Han, Eun Chun;Yoon, Jonghee;Choi, Chulhee
    • Molecules and Cells
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    • v.38 no.1
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    • pp.89-94
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    • 2015
  • The shape and activity of mitochondria are tightly regulated by fusion and fission processes that are essential for maintaining normal cellular function. However, little is known about the involvement of mitochondrial dynamics in the development of the immune system. In this study, we demonstrate that mitochondrial dynamics play a role in the differentiation and migration of immature dendritic cells (imDCs). We show that mitochondrial elongation is induced during GM-CSF-stimulated differentiation of bone marrow progenitors to imDCs accompanied by upregulation of mitochondrial fusion proteins. These processes precede the changes in mitochondrial morphology and connectivity that occur during differentiation. Mfn2 and OPA1, but not Mfn1, are transcriptionally upregulated during differentiation; however, knockdown of Mfn2 and OPA1 does not induce any change in expression of CD11c, CDC80, or CD86. Notably, knockdown of Mfn2 or OPA1 by siRNA in imDCs significantly reduces CCR7 expression and CCL19-mediated migration. These results suggest that the mitochondrial fusion-related proteins Mfn2 and OPA1 are upregulated during bone marrow progenitor differentiation and promote the migration of imDCs by regulating the expression of CCR7.

Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice

  • Ranaweera, Sachithra S.;Dissanayake, Chanuri Y.;Natraj, Premkumar;Lee, Young Jae;Han, Chang-Hoon
    • Journal of Veterinary Science
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    • v.21 no.6
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    • pp.91.1-91.15
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    • 2020
  • Background: Sulforaphane (SFN) is an isothiocyanate compound present in cruciferous vegetables. Although the anti-inflammatory effects of SFN have been reported, the precise mechanism related to the inflammatory genes is poorly understood. Objectives: This study examined the relationship between the anti-inflammatory effects of SFN and the differential gene expression pattern in SFN treated ob/ob mice. Methods: Nitric oxide (NO) level was measured using a Griess assay. The inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression levels were analyzed by Western blot analysis. Pro-inflammatory cytokines (tumor necrosis factor [TNF]-α, interleukin [IL]-1β, and IL-6) were measured by enzyme-linked immunosorbent assay (ELISA). RNA sequencing analysis was performed to evaluate the differential gene expression in the liver of ob/ob mice. Results: The SFN treatment significantly attenuated the iNOS and COX-2 expression levels and inhibited NO, TNF-α, IL-1β, and IL-6 production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. RNA sequencing analysis showed that the expression levels of 28 genes related to inflammation were up-regulated (> 2-fold), and six genes were down-regulated (< 0.6-fold) in the control ob/ob mice compared to normal mice. In contrast, the gene expression levels were restored to the normal level by SFN. The protein-protein interaction (PPI) network showed that chemokine ligand (Cxcl14, Ccl1, Ccl3, Ccl4, Ccl17) and chemokine receptor (Ccr3, Cxcr1, Ccr10) were located in close proximity and formed a "functional cluster" in the middle of the network. Conclusions: The overall results suggest that SFN has a potent anti-inflammatory effect by normalizing the expression levels of the genes related to inflammation that were perturbed in ob/ob mice.

Analyzing the Effect of COVID-19 on the Operational Efficiency of Asia's Major Container Ports: A Data Envelopment Analysis (COVID-19 위기가 아시아 주요 컨테이너항만의 운영효율성에 미치는 영향)

  • KIM, Tae-Hyung;CHOI, Sang-Duk
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.27 no.6
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    • pp.763-774
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    • 2021
  • The COVID-19 virus has generated major shockwaves in all spheres of human life since its outbreak. Maritime transport (both cargo and passenger) is one of the industries most heavily affected, yet over 80% of the world cargo is transported by sea. This study analyzes maritime port operational efficiencies before and after the start of the COVID-19 pandemic to determine whether the pandemic has caused major differences in the operational efficiencies of many leading Asian maritime container ports via data envelopment analysis (DEA). The results of both the CCR and BCC models reveal that overall, efficiency during the COVID-19 pandemic has been higher than before the pandemic despite a few inefficiencies. This implies that the pandemic has so far not has major consequences for the operational efficiency of maritime ports. However, two ports (Busan and Guangzhou) should adjust the scale sizes and technical capacities of their operations to improve performance.