• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.7
• /
• pp.3305-3311
• /
• 2012

Background: The present study aimed to find the prognostic implications of two polymorphisms in TP53 (p.R72P, PIN3 Ins16bp) and one in CCR5 ($CCR5{\Delta}32$) in sporadic breast cancer patients. Methods: DNA samples of 80 breast cancer patients and 80 age and gender matched unrelated healthy control individuals from Punjab, North West India were analyzed. Results: For p.R72P, the genotype frequency was 13.8% (RR), 58.8% (RP), 27.5% (PP) in patients and 33.9% (RR), 40.0% (RP), 26.5% (PP) in controls. For PIN3 Ins16bp, the genotype frequencies were 53.75% (A1A1), 37.5% (A1A2), 8.75% (A2A2) in patients and 66.3% (A1A1), 31.3% (A1A2), 2.5% (A2A2) in controls. Only 4 (5%) breast cancer patients were heterozygous for $CCR5{\Delta}32$ deletion. Common RR-A1A1-WT/WT genotype was lower while RP-A1A2-WT/WT genotype was higher in patients as compared to controls. RP-A1A1-WT/WT genotype was significantly higher in patients as compared to control individuals (p = 0.008). Conclusion: Though a clear association of any particular genotype with sporadic breast cancer or stage was not apparent, the results of present study were suggestive that sporadic breast cancer patients with RR-A1A1-WT/WT genotype might have a better response to chemotherapy, thus improving their chances of survival.

• Progress in Superconductivity
• /
• v.4 no.2
• /
• pp.172-175
• /
• 2003

Critical current ratio and n-value of Bi(2223)/Ag superconducting joint tape were measured as a function of uniaxial pressure. In the superconducting joint method, MM and MSM joint were used ; MM joint is direct connection of two -multi filamentary tapes, and MSM is connection of them by using a single -filamentary tape. It was observed that the critical current ratio(CCR) for jointed tapes was not dependent on the uniaxial pressure but joining methods. The n-value of jointed tapes has similar trends with that of the CCR. Especially, double MSM joint showed the highest electrical properties as 63.4-76.0%(CCR) and 3.5-5.1 (n-value). It is considered that the improvements are due to the better inter connections of multifilaments by two single filamentary tapes on both sides.

• The Journal of the Korea Contents Association
• /
• v.8 no.4
• /
• pp.173-182
• /
• 2008

It is hard environment to get a profit without active invest due to the low interest. In this kind of environment, however, it is also difficult to find good company directly. So private investors is hard to succeed in comprehensive financial environment. Analyzing efficiency is necessary to enhance the competitive power of fund companies. This paper analyze the efficiency of fund company using DEA models. We evaluate the CCR and BCC efficiency and RTS(return to scale) of 33 Korean fund companies. We also suggest the fund company which can be benchmarked based on analyzed information.

• Korean Journal of Organic Agriculture
• /
• v.30 no.4
• /
• pp.499-516
• /
• 2022

Blueberry producers' management is failing as a result of the price decline caused by an increase in blueberry imports and the accompanying deterioration in management. Consequently, an endeavor was undertaken to verify the measurement and impact from the standpoint of efficiency and productivity of blueberry management, and to offer an indication of management improvement through analysis. Using the Rural Development Administration's income survey data, the data for twenty-four blueberry farms was analyzed. First, the management effectiveness of blueberry cultivators was evaluated. Using the CCR model (0.7297) and the BCC model (08148), the efficiency of a farm was examined. When the efficiency is one, CCR is ten and BCC is fifteen, and in overall, it was found to be ineffective, the efficiency declined from 2018 to 2019, but climbed again in 2020, according to the annual analysis. The MPI index was then used to examine productivity. T2's MPI index was 1.3338, whereas T3's MPI index was 0.8896, demonstrating a considerable decline in TC. This indicates that technological progress is not being accomplished, necessitating the need for countermeasures. In order to improve the management efficiency of blueberry producers, it is necessary to reduce costs and improve receivable prices through producer organization, and to actively introduce new technologies.

• The Journal of the Korea Contents Association
• /
• v.9 no.5
• /
• pp.224-229
• /
• 2009

This study measures the relative efficiency and productivity change of the Korean Non-Life Insurance Firms using DEA model and Malmquist Index for 2004-2007. The main results of this study can by summarized as follows. First, in case of efficiency of CCR for 2004-2007, the number of efficient firms(CCR value is one) are one firm, one firm, one firm, one firm respectively. Second, in case of efficiency of BCC for 2004-2007, the number of efficient firms(BCC value is one) are five firms, five firms, six firms, six firms respectively. Third, In case of return to scale for 2004-2007, DRS are five firms, DRS are five firms, DRS are six firms, DRS are six firms respectively, Fourth, Malmquist Index representing productivity change for 2004-2007 are 0.99 in 2004-2005, 1.04 in 2005-2006, 1.06 in 2006-2007.

• Journal of Korea Port Economic Association
• /
• v.28 no.4
• /
• pp.59-77
• /
• 2012

Inland transportation system has been improving inefficiencies and structural problems due to excess of supply. Therefore, inland transportation market needs to reform its regional logistics structure in order to increase its competitiveness. To improve the solution, the research studied efficiencies and productivity of inland transportation systems in regions. In order to obtain specific facts, each cities' five years of (2005-2009) balanced panel data on inland transportation system has been studied. According to CCR and BCC analysis, Ul-San has been evaluated as the most efficient DMU during 2005-2008. In addition, in 2009, Seoul was the most efficient DMU. Also, according to Window analysis, Gwan-Ju and Gwangwon-do scored 0.062. Therefore, they were estimated as stable DMUs. According to Malmquist productivity analysis, average productivity indexes of four terms of Chungcheongnam-do and Chungcheongbuk-do haves been increased to 6.6% and 7.3%. I hope this study contributes to the improvement of regional inland transportation system.

• The Journal of the Korea Contents Association
• /
• v.22 no.5
• /
• pp.165-173
• /
• 2022

Recently, competition to provide specialized services for the information and communications industry has accelerated in terms of future technology and investment strategy of the Fourth Industrial Revolution. Technological innovations related to information and communications can be seen as increasing productivity, creating added value for companies, and playing a pivotal role in the development of economic growth. Therefore, efficient management of the information and communications industry is important. This study analyzes management efficiency stones for the top 30% of KOSDAQ-listed information and communications companies using dea, presents projected values of companies for efficient operation, and confirms benchmarking company references. We evaluated CCR efficiency, BCC efficiency, ranking, Scale Efficiency(SE), and Return To Scale (RTS) of KOSDAQ-listed information and communications businesses. The analysis showed CCR efficiency of 1, 14 companies, and 1 BCC efficiency, and Nanatan companies were analyzed as ten companies. Scale yield was analyzed by the IRS as four companies, 13 CRS and 13 DRS companies.

• The Journal of the Korea Contents Association
• /
• v.9 no.4
• /
• pp.323-330
• /
• 2009

This study measures the relative efficiency and productivity change of the Korean Life Insurance Firms using DEA model and Malmquist Index for 2004-2007. The main results of this study can by summarized as follows. First, in case of efficiency of CCR for 2004-2007, the number of efficient firms(CCR value is one) are six firms, five firms, four firms, seven firms respectively. Second, in case of efficiency of BCC for 2004-2007, the number of efficient firms(BCC value is one) are eight firms, nine firms, ten firms, twelve firms respectively. Third, In case of return to scale for 2004-2007, DRS are nine firms and IRS are two firms, DRS are five firms and IRS are five firms, DRS are five firms and IRS are four firms, DRS are five firms and IRS are two firms respectively, Fourth, Malmquist Index representing productivity change for 2004-2007 are 1.12 in 2004-2005, 0.97 in 2005-2006, 1.05 in 2006-2007.

• The Journal of Pediatrics of Korean Medicine
• /
• v.23 no.2
• /
• pp.51-85
• /
• 2009

Objectives : The purpose of this study is to investigate the effect of concurrent administration of KKSDU and AJ on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the condition in humans. Methods : We evaluated clinical skin score, hematology, serum total IgE and IgG1 of NC/Nga atopic dermatitis mouse and analyzed the cytoline level, total cell number, immunohistochemical staining, histological features of axillary lymph node(ALN), draining lymph node(DLN), peripheral blood mononuclear cells(PBMCs) and dorsal skin tissue in NC/Nga mouse. Results : Orally administration of KKSDU and concurrent administration of KKSDU and AJ decreased the clinical skin score, total cell number of WBC, platelet, neutrophils, eosinophils in blood, serum total IgE & IgG1, IL-5, IL-13. Also, total cell number of ALN and dorsal skin tissue, absolute cell number of CD3e+&CD19+, CD4+&CD8+, CD3+/CCR3+, CCR3+, CD3+/CD69+, CD3+/CXCR5+ in ALN, PBMCs, absolute cell number of CCR3+, CD3+/CD69+, CD11b+/Gr-1+ in dorsal skin tissue, Eotaxin2 mRNA, CCR3 mRNA in dorsal skin tissue and gene expression of IL-5 mRNA, IL-13 mRNA in ALN are significantly decreased. Furthermore, thickness of epidermis, infiltrated inflammatory immune cell & mast cell in dermis, histologic infiltration of mast cell, the size of inflammatory lymphocytes cells & plasma cells in ALN and histologic infiltration of CD4+ & CCR3+ in ALN and dorsal skin tissue are significantly decreased. However, total cell number of DLN, absolute cell number of CD3+&CD19+, CD4+&CD8+, B220+/CD23+, CD3+/CD69+ in DLN and CD4+CD25+foxp3+Treg cell, foxp3 mRNA in dersal skin tissue are increased significantly. Conclusions : Concurrent administration of KKSDU and AJ on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse was very effective to the atopic detmatitis treatment.

• Journal of Yeungnam Medical Science
• /
• v.5 no.1
• /
• pp.93-100
• /
• 1988

In clinical practice, creatinine clearance(Ccr) remains the most commonly used laboratory assessment of glomerular function despite methodological and technical problems of urine collection. Schwartz et al. in 1976, reported that an accurate estimate of glomerular filtration rate(GFR) could be obtained from the simple determinations of plasma creatinine(Pcr) and body length(L) : GFR($m{\ell}/min/1.73m^2$=k L(cm)/Pcr(mg/$100m{\ell}$), (k=constant). The subject of this study were ill children admitted to our pediatric department from July, 1985 to June, 1987 and they were divided into three groups; group I, from 1 to 5 years old, group II, from 6 to 10 years old, group III. from 11 to 15 years old. The results were as following ; 1) Measured creatinine clearance($Ccr_M$, $m{\ell}/min/1.73m^2$) were $109.73{\pm}9.97$ in group I, $108.26{\pm}9.02$ in group II, $96.20{\pm}4.72$ in group III and $105.48{\pm}5.23$ in all age group. 2) Measured k($k_M$) obtained from $Ccr_M=k$ Ht/Pcr were $0.49{\pm}0.03$ in group I, $0.48{\pm}0.02$ in group II, $0.43{\pm}0.02$ in group III, and $0.47{\pm}0.02$ in all age group.(Ht ; height) 3) Linear equations and correlation coefficients between Ht/Pcr(x) and Ccr(y) were y=0.822x-65.63(r=0.99) in group I, y=0.61x-23.46(r=0.72) in group II, y=0.18x+54.44(r=0.54) in group III and y=0.58x-22.13(r=0.81) in all age group. 4) $Ccr_E$ was again estiamted from linear equations between Ht/Pcr and $Ccr_M$ and $k_E$ was calculated with Ht/Pcr and $Ccr_E$ were $0.48{\pm}0.01$ in group I, $0.49{\pm}0.01$in group II, $0.43{\pm}0.01$ in group III and $0.47{\pm}0.00$ in all age group. 5) Consistant values of $k_E$ and $k_M$ were highly significant as 95~97.5% in group I and II, 90~95% in group III and 97.5~99% in all age group. In summary, we could estimate GFR with height, plasma creatinine and measured k($k_M$) according to the age in easy and rapid way.