• Title/Summary/Keyword: CCR4

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Efficiency Analysis of Total Logistics Provider (종합물류기업의 경쟁력 분석)

  • Park, Hong-Gyun
    • Journal of Korea Port Economic Association
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    • v.27 no.2
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    • pp.261-273
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    • 2011
  • Mega-corporations are emerging as a result of M&As (mergers and acquisitions) in the logistics industry. The global logistics market has progressed in a continuously competitive manner. Global logistics corporations provide integrated set of services, from production to disposal in order to manage the process efficiently throughout the diverse regions of the world. To advance into an total integrated logistics provider, the corporation must have professional knowledge in logistics and information technology which are necessary to deliver effective integrated logistics solutions. The government has integrated the logistics corporations both horizontally and vertically with the aim to foster logistics corporations possessing global competitiveness. Six years have passed since the implementation of the comprehensive (total) logistics industry certification system in pursuit of making Korea the hub for the Northeast Asian logistics market. This study compares and analyzes the efficiency of nine mega integrated logistics providers by applying the CCR model and BCC model. Each of the nine corporations is subject to certification as integrated logistics corporations. In Korea, nine corporations are certified individually as integrated logistics corporations out of the 31 logistics providers. The analysis showed that the Glovis was the most efficient integrated logistics provider reaching 100% in efficiency and displayed the highest efficiency for six consecutive years from 2005 to 2010. The study also found that the Glovis will be able to maintain 100% in efficiency rate, even though the input are increased over six times as many as those of 2010.

Data Envelopment Analysis of the Management Efficiency of National Shipping Enterprises in South Korea -Chiefly on the Corporate Entertainment and Advertisement Cost- (DEA모형을 이용한 국적선사의 경영효율성 분석 -접대비와 광고·선전비를 중심으로-)

  • Park, Hyun-Jun;Kim, Hyuna;Lim, Young-Tae
    • Journal of Korea Port Economic Association
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    • v.32 no.2
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    • pp.123-135
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    • 2016
  • This study uses Data Envelopment Analysis(DEA) to investigate the management efficiency of Korean shipping companies based on business administration costs such as corporate entertainment, advertisement, and labor costs. We analyze shipping enterprises listed on the Korean stock market of the period of 2010-2014. Corporate entertainment, advertisement and labor costs are used as input variables and sales and net income are used as output variables. We use technical efficiency, pure technical efficiency, scale efficiency and returns to scale to propose a plan to improve the efficiency of inefficiency decision-making units (DMUs). The results of the efficiency analysis show that six of the DMUs in the technical efficiency of CCR model and eight of the DMUs in the pure technical efficiency of BCC model are in efficient state. In terms of return to scale, six of the DMUs(24% of all DMUs) show increasing returns to scale, while 13 DMUs(52% of all DMUs) showdecreasing returns to scale. Because multiple efficient state for DMUs exist in the technical efficiency analysis, we conduct a super efficiency analysis. The results show that the efficient state of the twomost efficient DMUs are 1.314 and 1.243, respectively. This implies that these DMUs could maintain their current levels of the efficiency if they increase the amount spent on advertisements, corporate entertainment and labor costs by 31.4% and 24.3%. respectively. We conclude this study by providing the efficiency states of each DMU and target for improving the inefficiencies in each case.

Respiratory Protective Effect of Salvia plebeia R. Br. Extracts against Ambient Particulate Matter-induced Airway Inflammation (미세먼지 유도 기도염증에 대한 배암차즈기 추출물의 호흡기 보호 효과)

  • Song, Hyeongwoo;Ji, Kon Young;Kim, Bok Kyu;Yang, Won Kyung;Han, Chang Kyun;Shin, Han Jae;Park, Yang Chun;Hwang, Ji Sook;Kang, Hyung Sik;Kim, Seung Hyung
    • Korean Journal of Medicinal Crop Science
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    • v.25 no.5
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    • pp.269-281
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    • 2017
  • Background: Small particles increase airway inflammation upon reaching the alveoli. Here, we investigated the protective or therapeutic effects of Salvia plebeia R. Br. (SP_R) extracts on airway inflammation. Methods and Results: To investigate the anti-inflammatory activity of SP_R extracts, we measured their inhibitory effect on the production of reactive oxygen species (ROS) expression of inflammatory mediators, and immune cell infiltration in MH-S alveolar macrophage cells and in the ambient particulate matter (APM)-exposed airway inflammation mice model. The SP_R extracts inhibited the production of ROS and expression of IL-4, IL-10, IL-15, and IL-17A mRNA in APM-stimulated MH-S cells. Oral administration of SP_R extracts suppressed APM-induced inflammatory symptoms, such as high alveolar wall thickness, excess collagen fibers, decreased mRNA expression of chemokines (Ccr9, Ccl5, Ccr3), inflammatory cytokines (IL-15, TNF-${\alpha}$), and IL-4 Th2 cytokine in the lung. The SP_R extracts also inhibited ROS production, granulocyte ($CD11b^+Gr-1^+$) infiltration, IL-17A, TNF-${\alpha}$, macrophage inflammatory protein (Mip-2), and chemokine (C-X-C motif) ligand 1 (Cxcl-1) production in the airway. The specific compounds in the SR-R extracts that mediate the anti-inflammatory effects were identified. Conclusions: In this study, SP_R extracts effectively inhibited airway inflammatory responses, such as ROS production and granulocyte infiltration into the airway, by regulating the expression of chemokines and inflammatory cytokines.

An Analysis of Change in Efficiency of Department of Early Childhood Education in KOREA (3주기 및 4주기 교원양성기관 평가 후 전국 대학 유아교육과 효율성 분석)

  • Song, Woon-Kyung;Song, Yun-Kyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.5
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    • pp.517-529
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    • 2021
  • This study analyzes changes in the efficiency of the Department of Early Childhood Education in Korea to examine the effectiveness of the National Evaluation for Teacher Education Institution. We provide policy implications from exploring factors influencing efficiency and comparing characteristics of efficient and inefficient departments. With 149 Department of Early Childhood Education in Korea, DEA was conducted to estimate the relative efficiency, and the Tobit model was applied to explore factors affecting efficiency. The results confirm that the Department of Early Childhood in Korea is run efficiently, though there was no change in scale efficiency and relative efficiency after the two phases of the National Evaluation for Teacher Education Institution. The results show the number of books per student was significantly lower despite a significantly higher employment rate. Efficiency of college departments, department greater than 60 (per cohort), and department in metropolitan city (except Seoul area) is confirmed greater. These results provide policy implications on developing evaluation measure and processes to improve education quality and efficiency.

Speech Reinforcement Based on G.729A Speech Codec Parameter Under Near-End Background Noise Environments (근단 배경 잡음 환경에서 G.729A 음성부호화기 파라미터에 기반한 새로운 음성 강화 기법)

  • Choi, Jae-Hun;Chang, Joon-Hyuk
    • The Journal of the Acoustical Society of Korea
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    • v.28 no.4
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    • pp.392-400
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    • 2009
  • In this paper, we propose an effective speech reinforcement technique base on ITU-T G.729A CS-ACELP codec under the near-end background noise environments. In general, since the intelligibility of the far-end speech for the near-end listener is significantly reduced under near-end noise environments, we require a far-end speech reinforcement approach to avoid this phenomena. In contrast to the conventional speech reinforcement algorithm, we reinforce the excitation signal of the codec's parameters received from the far-end speech signal based on the G.729A speech codec under various background noise environments. Specifically, we first estimate the excitation signal of ambient noise at the near-end through the encoder of the G.729A speech codec, reinforcing the excitation signal of the far-end speech transmitted from the far-end. we specially propose a novel approach to directly reinforce the excitation signal of far-end speech signal based on the decoder of the G.729A. The performance of the proposed algorithm is evaluated by the CCR (Comparison Category Rating) test of the method for subjective determination of transmission quality in ITU-T P.800 under various noise environments and shows better performances compared with conventional SNR Recovery methods.

Analysis of the Efficiency of Entrepreneurship Support in Korean Universities (국내 대학의 창업지원 효율성 분석)

  • Heung-Hee Kim;Dae-Geun Kim
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.19 no.4
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    • pp.87-101
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    • 2024
  • This study aims to provide insights for the efficient utilization of resources by analyzing the entrepreneurship support efficiency of Korean universities. To identify the factors influencing the number of entrepreneurs, which is the primary goal of university entrepreneurship support, a multiple regression analysis was conducted, identifying five effective independent variables. Using these five identified independent variables as input variables and the number of entrepreneurs as the output variable, the DEA method was used to analyze the efficiency of entrepreneurship support for each university as of 2023. The analysis of 150 four-year universities in Korea showed that nine universities exhibited complete efficiency in both CCR and BCC models. Among the remaining 141 universities that showed inefficiency, the cause was scale for five universities, technology for two universities, and both scale and technology for 134 universities. Regarding the returns to scale, nine universities exhibited CRS, 79 exhibited IRS, and 62 exhibited DRS. Additionally, reference groups that could serve as benchmarks for improving the efficiency of inefficient universities were identified, and target values(projections) for each variable to achieve efficiency were also presented. Despite the limitations of the DEA model, this study helps each university identify the causes of inefficiency in their entrepreneurship support and derive specific improvements to enhance efficiency. This facilitates more efficient resource management and can positively impact the ultimate goals of university entrepreneurship support, such as regional economic development and job creation.

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The Search for Inhibitory Effect of Aroma Therapy on Allergic Asthma by Flow cytometer (유세포 형광 분석기를 통한 아로마 요법의 알러지 천식 억제 효과 탐색)

  • Kim, Gyu;Yun, Mi-Yeong;Kim, Dong-Hui
    • Journal of Haehwa Medicine
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    • v.12 no.2
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    • pp.145-156
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    • 2004
  • The purpose of this study was to investigate the inhibitory effect of the aroma therapy of three kinds of aroma oil mixtures on asthma. 1. The percentage of granulocytes/lymphocytes population in mouse OVA-induced asthma lung cells was decreased significantly compared with those of control group. 2. The number of CCR3+ cells, CD4+ cells, CD8+ cells, CD23 and CD3e+/CD69+ in lungs of the mice group treated with M1 were decreased significantly compared with those of control group. 3. The number of IgE+/B220+ cells in the lungs of the mice group treated with M1 decreased significantly compared with those of control group. But the number of B220+ cells in the lunes of the mice group treated with M1 didn't show significant difference compared with those of control group. 4. The number of Gr-1+/CD11b+ cells in lungs of the mice group treated with M1 didn't show significant difference compared with those of control group. But the number of CD11b+ cells in lungs of the mice group treated with M1 decreased significantly compared with those of control group.

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Decomposition and Super-efficiency in the Korean Life Insurance Industry Employing DEA

  • Lee, Hyung-Suk;Kim, Ki-Seog
    • International Journal of Contents
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    • v.4 no.3
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    • pp.1-9
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    • 2008
  • The Korean life insurance industry has undergone profound changes, such as the beginning of the variable insurance in July 2001 and the bancassurance enforcement in August 2003. However, little empirical research has analyzed data that includes the bancassurance of life insurance companies operating in Korea. In response to this lack of research, this paper applies DEA (data envelopment analysis) models to measure and decompose their efficiency. We discovered that life insurance companies operating in Korea are a little different in their composition ratio of inputs and outputs, due to the increased variety of distribution channels and new products. We provided efficiency scores, return to scale, and reference frequencies. We also decomposed CCR, BCC, and SBM efficiency into scale efficiency and MIX efficiency. So, we try to investigate whether the sources of inefficiency were caused by the inefficient operation of DMU, disadvantageous conditions, the difference of the composition ratio in inputs and outputs with reference sets, or any combination of the above. Most companies in the sample display had either constant or decreasing returns to scale. The efficiency rankings were less consistent among models and efficient DMUs. In response to this problem, we used the super-efficiency model to rank them and then compared the rankings of the DMUs among the various models. It was also concluded that the availability of panel data, rather than cross-sectional data, would greatly improve the validity of the efficiency estimates.

Anti-inflammatory Effect of 9-cis Retinoic Acid on the Human Mast Cell Line, HMC-1

  • Lee, Ji-Sook;Kim, In-Sik
    • Biomedical Science Letters
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    • v.13 no.2
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    • pp.149-152
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    • 2007
  • Mast cells play important roles in immune-related diseases, in particular, allergic diseases. Although 9-cis retinoic acid (9CRA) has been known as an immune regulator, its function in mast cells is not characterized well. In a previous paper, we demonstrated that 9CRA differentially decreases both CCR2 expression and the MCP-1-induced chemotactic activity of the human mast cell line, HMC-1 cells. In the present study, we examined the effects of 9CRA on the migration and expressions of inflammatory cytokines in HMC-1 cells. It was found that 9CRA significantly inhibited the migration of HMC-1 cells in response to stem cell factor (P<0.01), and it had no effect on the mRNA and protein expression of c-kit, a receptor binding to SCF. We further investigated the alternation of inflammatory cytokine expression and identified that 9CRA blocked the mRNA and protein expressions of Th2 cytokines such as interleukin (IL)-4 and IL-5. Taken together, our results demonstrate that 9CRA blocks SCF-induced cell movement and the protein secretion of IL-4 and IL-5, and this indicates that 9CRA may have anti-inflammatory effects on mast cells.

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Mechanism of Urinary Excretion of Sulfadiazine in the Rabbit (가토(家兎)에 있어서 Sulfadiazine의 뇨중(尿中) 배설기전(排泄機轉))

  • Ko, Suk-Tai;Chung, Chong-Nam;Ko, Ok-Hyun
    • Journal of Pharmaceutical Investigation
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    • v.2 no.1
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    • pp.18-30
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    • 1972
  • Renal pathways for excretion of sulfadiazine has been studied by standard clearance technique in the rabbit. 1. Large part of sulfadiazine filtered in the glomeruli is reabsorbed in the tubules, as visualized from the fact that Csd (clearance of sulfadiazine) amounts only a fraction of simultaneously measured Ccr (GFR). 2. Csd changed linearly with the rate of urine flow, whether it is increased by the duir etics or decreased by clamping u reter. 3. Csd remained unchanged until the plasma level of the Csdremained unchanged drug reached 10.0 mg%, and the amount transported in the tubules increased linearly with the increase in the load, exhibiting No maximum capacity for transport. 4. Csd was increased by 2,4-dinitrophenol which is an uncoupling agent of oxidative phosphorylation and decreased by probenecid which is on uricosuric agent. 5. During sodium bicarbonate infusion net secretion of sulfadiazine by tubules observed. All the evidences obtained in the rabbit indicated that sulfadiazine was reabsorbed by active, energy-requiring, or passive, simple diffusion, process, and secreted simultaneously by a probenecid-sensitive, active procss.

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