• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.311-320
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• 2018

This study was conducted to investigate the relationship among major satisfaction (MS), clinical competence (CC), career decision-making self-efficacy (CDMS), and career decision level (CDL) for undergraduate nursing students. A self-report instrument was used to measure MS, CC, CDMS, and CDL. Questionnaires were completed by 307 nursing students in three nursing colleges, and path analysis was employed to validate the proposed model and analyze the causal relationships among variables. Four constructs (MS, CC, CDMS, and career decision) were analyzed. To build a path model, MS and CC were linked to CDMS and career decision. The initial analysis suggested that the modification needed modification; therefore, a covariance link was added. The overall goodness of fit for indices indicated satisfactory path analysis. The indices were revealed as $x^2=2412$, GFI=0.996, AGFI=0.961, and RMSEA=0.068. As a result, the proposed model was acceptable with a good fit, and there were significant direct and indirect effects of paths in the model. Specifically, MS and CC had a direct influence on CDMS, and MS and CDMS directly affected CDL. Moreover, MS and CC had indirect effects on CDL through CDMS. These results imply that students' CDMS should be seriously considered when designing counseling programs for career guidance, and substantiality of CC education is needed to improve CDMS. These results may provide a practical guideline to provide educational intervention for nursing students.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2193-2197
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• 2012

Background: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate, and the role of MTHFR C677T polymorphism in cervical carcinogenesis is still controversial. Method: We performed a meta-analysis of all relevant case-control studies that examined any association between the C677T polymorphism and cervical cancer risk. We estimated summary odds ratios (ORs) with their confidence intervals (CIs) to assess links. Results: Finally, 10 studies with a total of 2113 cervical cancer cases and 2804 controls were included. Results from this meta-analysis showed that significantly elevated cervical cancer risk was associated with the MTHFR T allele in the Asian population under conditions of two genetic comparison models (for TT vs. CC, OR = 1.37, 95%CI 1.00-1.87, P = 0.050; for TT vs. TC+CC: OR = 1.34, 95%CI 1.01-1.77, P = 0.039). However, there was no obvious association between the MTHFR C677T polymorphism and cervical cancer risk in the other populations. Conclusion: The MTHFR C677T polymorphism is associated with cervical cancer risk in Asians, while any possible link in the Caucasian population needs further studies.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8093-8100
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• 2016

Background: Genetic and environmental factors play important roles in pathogenesis of digestive tract cancers like those in the esophagus, stomach and colorectum. Folate deficiency and methylenetetrahydrofolate reductase (MTHFR) as an important enzyme of folate and methionine metabolism are considered crucial for DNA synthesis and methylation. MTHFR variants may cause genomic hypomethylation, which may lead to the development of cancer, and MTHFR gene polymorphisms (especially C677T and A1298C) are known to influence predispositions for cancer development. Several case control association studies of MTHFR C677T polymorphisms and colorectal cancer (CRC) have been reported in different populations with contrasting results, possibly reflecting inadequate statistical power. Aim: The present meta-analysis was conducted to investigate the association between the C677T polymorphism and the risk of colorectal cancer. Materials and Methods: A literature search of the PubMed, Google Scholar, Springer link and Elsevier databases was carried out for potential relevant articles. Pooled odds ratio (OR) with corresponding 95 % confidence interval (95 % CI) was calculated to assess the association of MTHFR C677T with the susceptibility to CRC. Cochran's Q statistic and the inconsistency index (I2) were used to check study heterogeneity. Egger's test and funnel plots were applied to assess publication bias. All statistical analyses were conducted by with MetaAnalyst and MIX version 1.7. Results: Thirty four case-control studies involving a total of 9,143 cases and 11,357 controls were retrieved according to the inclusion criteria. Overall, no significant association was found between the MTHFR C677T polymorphism and colorectal cancer in Asian populations (for T vs. C: OR=1.03; 95% CI= 0.92-1.5; p= 0.64; for TT vs CC: OR=0.88; 95%CI= 0.74-1.04; p= 0.04; for CT vs. CC: OR = 1.02; 95%CI= 0.93-1.12; p=0.59; for TT+ CT vs. CC: OR=1.07; 95%CI= 0.94-1.22; p=0.87). Conclusions: Evidence from the current meta-analysis indicated that the C677T polymorphism is not associated with CRC risk in Asian populations. Further investigations are needed to offer better insight into any role of this polymorphism in colorectal carcinogenesis.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04d
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• pp.515-517
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• 2003

In this paper we examine the effects of the required portions of guard timing spaces in a MAC frame of ETSI BRAN HIPERLAN/2 system such as inter-mobile guard timing space in UL(Up Link) duration, inter-RCH(Random CHannel) guard timing space, sector switch guard timing space. In particular, we calculate the number of OFDM(Orthogonal Frequency Division Multiplexing) symbols required for these guard timing spaces in a MAC frame. We them evaluate the throughput of HIPERLAN/2 system as we vary parameter such as the guard time values defined in [2], the number of DLCCs(Data Link Control Connections), and the number of RCHs. Finally we show by numerical results that the portions for the 새심 summation of required guard timing spaces in a MAC frame are not negligible, and that they should be properly considered when trying to evaluate the performance of MAC protocol of HIPERLAN/2 system and also when determining the number of RCHs as well as the number of DLCCs in UL PDU trains at an AP/CC(Access Point/Central Controller).

• The KIPS Transactions:PartA
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• v.11A no.1
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• pp.49-56
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• 2004

The performance of the multiprocessor systems is limited by the several factors. The system performance is affected by the processor speed, memory delay, and interconnection network bandwidth/latency. By the evolution of semiconductor technology, off the shelf microprocessor speed breaks beyond GHz, and the processors can be scalable up to multiprocessor system by connecting through the interconnection networks. In this situation, the system performances are bound by the latencies and the bandwidth of the interconnection networks. SCI, Myrinet, and Gigabit Ethernet are widely adopted as a high-speed interconnection network links for the high performance cluster systems. Performance improvement of the interconnection network can be achieved by the bandwidth extension and the latency minimization. Speed up of the operation clock speed is a simple way to accomplish the bandwidth and latency betterment, while its physical distance makes the difficulties to attain the high frequency clock. Hence the system performance and scalability suffered from the interconnection network limitation. Duplicating the link of the interconnection network is one of the solutions to resolve the bottleneck of the scalable systems. Dual-ring SCI link structure is an example of the interconnection network improvement. In this paper, I propose a network topology and a transaction path algorism, which optimize the latency and the efficiency under the duplicated links. By the simulation results, the proposed structure shows 1.05 to 1.11 times better latency, and exhibits 1.42 to 2.1 times faster execution compared to the dual ring systems.

• Archives of Pharmacal Research
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• v.20 no.6
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• pp.550-554
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• 1997

Chlorambucil is known to alkylate primarily N7 of guanine and N3 of adenine to induce DNA monofunctional adducts and interstrand cross-links (ISC). We have investigated the sequence specificity for DNA ISC induced by chlorambucil using duplex oligomers containing a defined cross-linkable sequences $ 5^{I}-A*TT, 5^{I}-G*TTor5^{I}-G*CC$ under bar which asterisk indicates the potential cross-linking site and underlined base indicates the potential cross-linking site on the opposite strand. An analysis of 20% denaturing polyacrylamide gel electrophoresis showed that chlorambucil was albe to induce DNA ISC in the duplex oligomers containing a sequence $5^I-GCC$. The formation of DNA ISC was not observed in the duplex oligomers containing sequences $5^I-ATT$. or $5^I-GTT$. These results indicate that chlorambucil induces guanine-guanine DNA ISC but not guanine-adenine or adenine-adenine DNA ISC. In addition, we have tested the ability of chlorambucil to induce DNA ISC within $5^I-GNNC$ or $5^I-GNNC$sequences using duplex oligomers containing the sequence$5^I-G^4G^3G^2^C$. The result of DNA strand cleavage assay showed that DNA ISC was formed at the $5^I-GGC$ sequence (an 1,3 cross-link, $G^1-G^3$) but not at $5^I-GGGC$ (an 1,4 cross-link, $G^1-G^4$) or $5^I-GC$ sequence (an 1,2 cross-link, $G^1-G^2$).

• Proceedings of the KIPE Conference
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• 2004.07a
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• pp.82-86
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• 2004

In this paper, a cycler system for the Lithium-Polymer battery with the large capacity of 120Ah is presented. This system is constituted as the two units for the charging and discharging. The Lithium-Polymer battery should be charged in CC and CV mode, and it is required a very high precision control of the voltage and current for the charging unit. To decrease the switching noises and harmonics, parallel operation method is adopted and utilized in the power conversion module. The discharging unit has a link AC system function to return the discharging energy of battery to AC line and has comparatively less thermal loss. These units are designed to be controlled and monitored by personal computer. The total system for the battery charging and discharging is described and presented.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.2 no.4
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• pp.194-208
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• 2008

In this paper, a multiple-input-multiple-output (MIMO) hybrid-automatic repeat request (HARQ) algorithm with antenna scheduling is proposed. It retransmits the packet using scheduled transmit antennas according to the state of the communication link, instead of retransmitting the packet via the same antennas. As a result, a combination of conventional HARQ systems, viz. chase combining (CC) and incremental redundancy (IR) are used to achieve better performance and lower redundancy. The proposed MIMO-OFDM HARQ system with antenna scheduling is shown to be superior to conventional MIMO HARQ systems, due to its spatial diversity gain.

• Proceedings of the KIPE Conference
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• 2019.07a
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• pp.295-296
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• 2019

본 논문은 넓은 출력전압 범위와 High Power Density를 위한 절연형 HMF PFC(Isolated Harmonic Modulation PFC)를 제안한다. 제안된 PFC는 변압기 leakage inductance를 회로에 적용시켜 switching device의 voltage stress를 효과적으로 줄일 수 있는 voltage-fed형태의 ful-bridge구조를 기반으로 한다. 출력 측 CV(Constant Voltage) control을 통하여 출력 혹은 link 전압을 load 변동에 상관없이 일정 유지시켜준다. 또한 CC(Constant Current) control 방식을 사용하여 출력 측 battery 특성 조건이 변동되어도 일정하게 충전시켜 줄 수 있도록 한다. HMF 제어방식을 적용한 3.3kW Prototype을 통해 이를 입증한다.

• Journal of the Institute of Convergence Signal Processing
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• v.9 no.4
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• pp.304-312
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• 2008

Orthogonal codes like Walsh and Golay codes may have large correlation value when they are not synchronized, hence they are seldom used in asynchronous CDMA systems. Wysocki[1] showed that by multiplying the original Walsh-Hadamard matrix with an orthogonal transformation matrix the resultant matrix sustains orthogonality between row vectors and their cross-correlation can be reduced. Soberly and Wysocki[2] proposed similar scheme on Golay codes. This implies that using the proper orthogonal transformation cross-correlation of Walsh and Golay codes can be reduced, and the transformed codes can be used for user separation in the CDAM reverse link. In this paper we discuss cross-correlation related parameters which affect the performance of an asynchronous CDMA link, and we investigate the correlation properties of the transformed codes. When we designed orthogonal transformation matrices for Walsh and Golay codes, we minimized the maximum value of aperiodic cross-correlation of the codes ($ACC_{max}$) or the mean square value of the aperiodic cross-correlation($R_{cc}$) with preserving the orthogonality of the modified codes. We also evaluate the asynchronous CDMA system that uses the transformed Walsh and Golay codes.