• Journal of Broadcast Engineering
• /
• v.20 no.6
• /
• pp.862-870
• /
• 2015

The RDO (Rate Distortion Optimization) process of HEVC results in good coding efficiency, but relatively requires much encoding time. In order to reduce the encoding time of RDO process, this paper proposes a method of fast intra prediction mode decision using DCT coefficients distributions and the existence of DCT coefficients. The proposed fast Intra coding sets the number of intra prediction mode candidates to three(3) from the RMD (Rough Mode Decision) process in HM16.0 reference SW and reduces the number of candidates one more time by investigating DCT coefficients distribution. After that, if there exists a quantized DCT block having all zero coefficient values for a specific candidate before the RDO process, the candidate is chosen without the RDO process. The proposed method reduces the encoder complexity on average 46%, while the coding efficiency is 2.1% decreased compared with the HEVC encoder.

• Korean Journal of Biological Psychiatry
• /
• v.17 no.3
• /
• pp.127-135
• /
• 2010

Objectives : This study was conducted to compare between hallucination group and delusion group in patient with schizophrenia, using Brain $^{99m}Tc$-ECD PECT. Methods : Among 16 patients with less than 3 schizophrenic episodes, 8 patients whose initial symptom was hallucination were assigned to the hallucination group, and other 8 patients with initial sumptom of delusion were assinged to the hallucination group. All of the patients clinically evaluated using the PANSS and BPRS. Both groups of patients and 8 healthy subjects underwent $^{99m}Tc$-ECD PECT. Results : Score of thinking disturbance subscale of BPRS were significantly lower in the hallucination group than the delusion group. In SPECT analysis, the hallucination group showed significantly increased perfusion in some areas of the right temporal lobe, bilateral limbic lobes and left parietal lobe compared to delusion group. Both group had a reduced rCBF in some areas of the frontal lobe. Conclusion : The hallucniation group, compared with the delusion group, showed significantly increased regional cerebral blood flow in some regions. Therefore, this data suggests that different neural substrates may affect the process of auditory hallucination and delusion.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.17 no.1
• /
• pp.1-9
• /
• 2013

In this study of Eccentric Braced Frames have identified the following target eccentricity on the length of the inelastic behavior of the reaction by calculating the correction factor by comparing it to the value suggested by the earthquake provided material for the rational design aims to There are. As a variable-length V-braced frame analysis model stations were set up. Eccentricity faults in the model according to the length stiffness ratio, the maximum amount of energy dissipation were analyzed base shear and multi-layered model of the reaction from the eccentricity correction factor calculated on the length of the building standards proposed by KBC 2009 in response eccentricity correction factor calculated from The length varies. does not have the same response modification factor was confirmed.

• Proceedings of the KOSOMBE Conference
• /
• v.1998 no.11
• /
• pp.281-282
• /
• 1998

Recently, there has been growing interest in the assessment of physiological parameters on brain perfusion that provide more information than pure morphologic diagnosis. Quantification of parameters that characterize cerebral micro-circulation with magnetic resonance imaging is of great relevance for clinical application. We determine the local tissue concentration by exponential relationship between the relative signal reduction S(t)/$S_0$ and local tissue concentration of contrast material $C_m(t)$ in dynamic susceptibility contrast enhanced MR imaging. And then we made relative regional blood volume map by calculating the area under the measured concentration-time curves $C_m(t)$ during first pass of paramagnetic contrast material as a preliminary step for perfusion map. These images make it possible to compare the rCBV in different brain regions in one individual at a time. We have it in contemplation to obtain arterial and brain signal time curves simultaneously to make absolute rCBV and perfusion (rCBF) map. These maps may provide the method of comparative investigations of different patients having strong variation in AIF.

• Journal of Food Hygiene and Safety
• /
• v.2 no.2
• /
• pp.57-65
• /
• 1987

ABSTRACT - To examine antihypertensive components of Ganoderma lucidum in Korea, two kinds of fruiting bodies (J and K) were used for extraction with water and the extracts were purified by ethanol precipitation and dialysis. Three fractions, i.e., the aqueous total extract(A), the ethanol supernatant(B} and the purified precipitate(C), were compared for antihypertensive activity in anesthetized spontaneously hypertensive rats (SUR). Although fractions A and B showed the activity, fraction C did not. Particularly, fraction B of sample K produced 44.3% reduction in diastolic blood pressure and 30.6% reduction in heart rate after i.v. administration of a dose of 10 mg/kg. Direct effects of this fraction B to the heart were observed in the isolated blood perfused heart preparation of the dog. It induced positive chronotropic and inotropic responses dose-dependently in the case of sample J. In the case of sample K, marked chronotropic and inotropic effects on atrial muscle but not on ventricular muscle were induced. In both samples, coronary blood flow (CBF) was dose-relatedly increased.reased.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.32 no.8A
• /
• pp.827-835
• /
• 2007

In this paper, the extension method of data transmission range as adapting AAS(Adaptive Antenna Systems) in ECMA(European Computer Manufacturers Association) standard MB-OFDM(MultiBand-Orthogonal Frequency Division Multiplexing) UWB systems is proposed, and the complementary beamforming method which can solve hidden beam problem when we adapt AAS in CSMA/CA(Carrier Sense Multiple Access with Collision Avoidance) systems is proposed. To design the complementary beamforming, Gram-Schmidt orthogonalization is utilized, whose beam pattern exhibits perfect nulling at the main beam angles and provides uniform power for detection of channel utilization out of main beam. The proposed method can be utilized with any arbitrary beamforming when we make main beamforming. Through computer simulation, it can be shown that proposed AAS and complementary beamforming increase data transmission range from 2m to 3.95m in 480Mbps data transmission system and increase throughput about 20% as compared with general UWB AAS systems.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.33 no.12A
• /
• pp.1165-1171
• /
• 2008

In this paper, a pilot emitting amplify-and-forward relay and its beamforming schemes, OBF (overall beamforming) and RBF (hop-by-hop beamforming), are proposed for two-hop relaying systems. The OBF performs beamforming with respect to a overall channel from a source node (SN) to a destination node (DN) through a relay node (RN), while the proposed RBF performs two independent beamformings: from the SN to the RN and from the RN to the DN. From our analytic and numerical results, it is shown that bit-error-rate (BER) performance of the proposed RBF is better than that of the OBF scheme since the RBF system can estimate channel more proper than the CBF system, which is verified by deriving and comparing the mean square errors of the channel estimation.

• Molecules and Cells
• /
• v.41 no.9
• /
• pp.842-852
• /
• 2018

Notch signaling is an evolutionarily conserved pathway and involves in the regulation of various cellular and developmental processes. Ligand binding releases the intracellular domain of Notch receptor (NICD), which interacts with DNA-bound CSL [CBF1/Su(H)/Lag-1] to activate transcription of target genes. In the absence of NICD binding, CSL down-regulates target gene expression through the recruitment of various corepressor proteins including SMRT/NCoR (silencing mediator of retinoid and thyroid receptors/nuclear receptor corepressor), SHARP (SMRT/HDAC1-associated repressor protein), and KyoT2. Structural and functional studies revealed the molecular basis of these interactions, in which NICD coactivator and corepressor proteins competitively bind to ${\beta}-trefoil$ domain (BTD) of CSL using a conserved ${\varphi}W{\varphi}P$ motif (${\varphi}$ denotes any hydrophobic residues). To date, there are conflicting ideas regarding the molecular mechanism of SMRT-mediated repression of CSL as to whether CSL-SMRT interaction is direct or indirect (via the bridge factor SHARP). To solve this issue, we mapped the CSL-binding region of SMRT and employed a 'one- plus two-hybrid system' to obtain CSL interaction-defective mutants for this region. We identified the CSL-interaction module of SMRT (CIMS; amino acid 1816-1846) as the molecular determinant of its direct interaction with CSL. Notably, CIMS contains a canonical ${\varphi}W{\varphi}P$ sequence (APIWRP, amino acids 1832-1837) and directly interacts with CSL-BTD in a mode similar to other BTD-binding corepressors. Finally, we showed that CSL-interaction motif, rather than SHARP-interaction motif, of SMRT is involved in transcriptional repression of NICD in a cell-based assay. These results strongly suggest that SMRT participates in CSL-mediated repression via direct binding to CSL.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.32 no.2
• /
• pp.207-210
• /
• 2003

This study was designed to investigate the antioxidative effect of glasswort (Salicornia herbacea L.) grown in closed sea beach. To compare antioxidant effects of glasswort plant parts, dried ground leaves, stems, and roots of glasswort were exploited for investigation of antioxidant activity Antioxidant activity for the samples was investigated by Rancimat and TBA method. The oxidative stability determined by the Rancimat technique showed a variation in antioxidative index (AL) between the different plant parts, ranging from 1.0 to 3.6. Oxidative stability from ground stem sample of glasswort harvested in the closed sea beach was the highest, and followed by leaf and root. Stem had higher oxidative stability than ascorbic acid. Antioxidatiue effects of glasswort were increased in dose-dependent manners, and antioxidant activity by addition of glasswort with same amount to 4% oil was similar to the activity of ascorbic acid. Specially, 8~10% glasswort addition to oil showed similar antioxidative effect to 1% $\alpha$-tocopherol.

• Journal of Haehwa Medicine
• /
• v.10 no.2
• /
• pp.11-19
• /
• 2002

To evaluate the antitumor activity and antimetastatic effects of Bruceae FructusCBF), studies were done experimentally. The results were obtained as follows : 1. In cytotoxicity against A549, SK-MEL-2, MCF-7 and XF498 cell concentration inhibiting cell growth up to below 50% of control was recognized at $25{\mu}g/m{\ell}$ of BF. Also BF inhibited cell growth up to below 50% of control against HCT15 cell at $12.5{\mu}g/m{\ell}$, so it showed stronger cytotoxicity against HCT15 cell than another cancer cell. 2. In Inhibitory effect on activity of DNA topoisomerase- I, the $IC_{50}$ was shown $10-50{\mu}g/m{\ell}$ of BF. 3. The T/C% was 143.4 in BF treated group in S-180 bearing ICR mice. 4. The concentration inhibiting adhesion of A549 and SK-OV-3 to complex extracellular matrix up to below 30% of control was recognized at $1{\mu}g/m{\ell}$ of BF. 5. In pumonary colonization assay, a number of colonies in the lungs were decreased significantly in BF treated group as compared with control group. These results suggested that BF extracts might be usefully applied for prevention and treatment of cancer.