• Title/Summary/Keyword: CAT-2

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Different Pattern of Chronic Obstructive Pulmonary Disease Assessment Test Score between Chronic Bronchitis and Non-chronic Bronchitis Patients

  • Yoo, Sang Hoon;Lee, Jae Ha;Yoo, Kwang Ha;Jung, Ki-Suck;Rhee, Chin Kook
    • Tuberculosis and Respiratory Diseases
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    • v.81 no.3
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    • pp.228-232
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    • 2018
  • Background: Chronic bronchitis (CB) is an important phenotype in chronic obstructive pulmonary disease (COPD). The purpose of this study is to evaluate different pattern of COPD assessment test (CAT) score between CB and non-CB patients. Methods: Patients were recruited from 45 centers in Korea, as part of the Korean COPD Subgroup Study cohort. CB was defined when sputum continued for at least 3 months. Results: Total 958 patients with COPD were eligible for analysis. Among enrolled patients, 328 (34.2%) were compatible with CB. The CAT score was significantly higher in patients with CB than non-CB, and each component of CAT score showed a similar result. CB was significantly associated with CAT score when adjusted with age, sex, modified Medical Research Council, and post-bronchodilator forced expiratory volume in 1 second. Each component of CAT score between patients with CB and non-CB showed different pattern according to Global Initiative for Chronic Obstructive Lung Disease grade. Conclusion: CAT score is significantly higher in patients with CB than non-CB. Each component of CAT score was significantly different between two groups.

Cloning of Promoters from Alkali-tolerant Bacillus sp. (알카리 내성 Bacillus속 Promoter의 Cloning)

  • 유주현;구본탁;공인수;정용준;박영서
    • Microbiology and Biotechnology Letters
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    • v.16 no.2
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    • pp.126-130
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    • 1988
  • Promoters of an alkali-tolerant Bacillus sp. isolated from soil have been cloned in Bacillus subtilis using promoter probe vector pPL703. The CAT specific activity of a clone harboring the strongest promoter activity among these transformants was 8.01. This activity was 2.5 times higher than that of Bacillus subtilis harboring expression vector pPL708 and was increased after the end of the logarithmic growth phase. In the 2.8kb of inserted DNA fragment, BamHI and Sal I recognition sites were located.

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Cellular Automata Transform based Invisible Digital Watermarking in Middle Domain for Gray Images

  • Li, Xiao-Wei;Kim, Seok-Tae
    • Journal of information and communication convergence engineering
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    • v.9 no.6
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    • pp.689-694
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    • 2011
  • Cellular automata are discrete dynamical systems, which provide the basis for the synthesis of complex emergent behavior. This paper proposes a new algorithm of digital watermarking based on cellular automata transform (CAT). The idea of two-dimensional CAT is introduced into the algorithm. After the original image is disassembled with 2D CAT, the watermark information is embedded into the Middle-frequency of the carrier picture. Cellular automata have a huge number of combinations, such as gateway values, rule numbers, initial configuration, boundary condition, etc. Using CAT, the robustness of the watermark will be tremendous strengthened as well as its imperceptibility. Experimental results show that this algorithm can resist some usual attacks such as compression, sharpening and so on. The proposed method is robust to different attacks and is more security.

Screening and Isolation of Antibiotics Resistance Inhibitors from Herb Materials. V.- Resistance Inhibition by Acorenone from Acorus gramineus Solander

  • Kim, Hye-Kyung;Moon, Kyung-Ho;Lee, Chung-Kyu
    • Natural Product Sciences
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    • v.6 no.1
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    • pp.36-39
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    • 2000
  • Acorenone, a diterpene isolated from Acorus gramineus, showed strong resistance inhibitory activity against multi-drug resistant microorganisms such as Staphylococcus aureus SA2, which has resistance to 10 usual antibiotics including chloramphenicol (Cm). At the level of $5\;{\mu}g/ml$ when combined with $50\;{\mu}g/ml$ of Cm. Bacterial resistance to Cm is due to the presence in resistant bacteria of an enzyme, chloramphenicol acetyltransferase (CAT), which catalyses the acetyl-CoA dependent acetylation of the antibiotic at C-3 hydroxyl group. To elucidate the mechanism of resistant inhibitory effect, the acorenone which had the strongest resistant inhibitory activity, was investigated on the CAT assay. As the result, the combination of Cm and acorenone showed the strongest inhibitory activity on CAT as noncompetitive and dose dependent manner.

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Diaphragmatic deformity in a cat mimicking a cardiac mass

  • Choi, Ran;Lee, Seung-Gon;Moon, Hyeong-Sun;Hyun, Changbaig
    • Korean Journal of Veterinary Research
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    • v.48 no.2
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    • pp.209-213
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    • 2008
  • A four-month-old intact femlae Abyssinian cat was present for routine health evaluation, because her littermate was recently died of ventricular septal defect. Diagnostic imaging studies showed a large caudal paracardiac mass in thoracic radiography and homogenous mass adjacent to heart in the echocardiography. Further echographic study revealed that the mass was liver and the diaphragmatic line was intact. The positive contrast celiogram revealed that no extravasation of the contrast media across the diaphragm and the prolapse of diaphragm into the pleural cavity. Based on our diagnostic imaging studies, the case was diagnosed as diaphragmatic deformity in a cat mimicking a cardiac mass.

A Simple Method for Cat Bone Marrow-derived Mesenchymal Stem Cell Harvesting

  • Jin, Guang-Zhen;Lee, Young-Soo;Choi, Eu-Gene;Cho, Kyu-Woan;Kong, Il-Keun
    • Journal of Embryo Transfer
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    • v.23 no.2
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    • pp.127-131
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    • 2008
  • Bone marrow (BM) cell harvesting is a crucial element in the isolation of mesenchymal stem cells (MSCs). A simple method for harvesting cat BM cells is described. The results show that a large number of BM cells can rapidly be harvested from the cat by this simple procedure. MSCs prepared by density-gradient method were spindle-shaped morphology with bipolar or polygonal cell bodies and strongly positive for CD9 and CD44 and negative for CD18 and CD45-like. They were capable of differentiation to adipocytic and osteocytic phenotypes when exposed to appropriate induction media. The advantages of this method are its rapidity, simplicity, low invasiveness, and low donor attrition and good outcome.

Diagnostic Imaging of Tricuspid and Mitral Valve Dysplasia in a Cat (고양이에서 삼첨판과 승모판의 형성이상 진단 증례)

  • Jung, Joo-Hyun;Chae, Woong-Joo;Chang, Jin-Hwa;Kim, Dae-Yong;Yoon, Jung-Hee;Choi, Min-Cheol
    • Journal of Veterinary Clinics
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    • v.24 no.3
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    • pp.444-448
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    • 2007
  • An intact female, 2 month old, domestic short hair cat, weighing 0.82kg with a history of respiratory distress, anorexia, and depression for 3 days was referred. In laboratory examination, there were no remarkable abnormalities. Radiographic findings mainly included pleural effusion, dilation of pulmonary vessels, pulmonary edema, and ascites. Echocardiography showed dilation of four cardiac chambers, malformation of the tricuspid and mitral valve, and atrioventricular valve regurgitant jet flow. The cat was euthanized by client's request and confirmed to the tricuspid and mitral valve dysplasia by necropsy and histopathologic examination.

Diagnostic imaging features of calyceal diverticulum in a cat

  • Nam, Yunjeong;Lee, Youngwon;Choi, Hojung
    • Korean Journal of Veterinary Research
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    • v.61 no.2
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    • pp.17.1-17.4
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    • 2021
  • A seven-year-old, castrated male, Korean domestic shorthair cat was referred because of a kidney abnormality. Radiography revealed left renal agenesis and right kidney enlargement. Ultrasonography and computed tomography (CT) showed amorphous calcified materials in a cyst-like lesion of the right kidney. In the excretory phase of the CT images, the lesion was opacified with contrast materials, indicating communication with the collecting system. Based on these findings, the cat was diagnosed with a calyceal diverticulum. A calyceal diverticulum may cause various clinical symptoms related to the urinary system. The excretory phase of CT is useful for diagnosing a calyceal diverticulum.

Tentative diagnosis and monitoring using ultrasound in a cat with pansteatitis: a case report

  • Kang, Hyesun;Noh, Daji;Lee, Sang-Kwon;Lee, Kija
    • Korean Journal of Veterinary Research
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    • v.62 no.1
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    • pp.7.1-7.4
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    • 2022
  • A 7-year-old Scottish Straight cat presented with hypersalivation and generalized hyperesthesia. The cat was provided tuna-based food for 2 to 3 weeks before clinical symptoms appeared. Abdominal ultrasonography showed a heterogeneous, hyperechoic mesentery with hypoechoic foci. Pansteatitis was tentatively diagnosed and the cat was treated with vitamin E, anti-inflammatory drugs, and dietary changes. The clinical signs and changes in mesenteric fat on serial ultrasonography resolved. After feeding tuna-based food again, the same clinical signs and mesenteric changes on ultrasound recurred, which recovered through the same treatment. This study suggests that ultrasonography can be useful for diagnosis and monitoring of feline pansteatitis.

Effects of Various Proteins on the Autoxidation of L-Ascorbic Acid (비타민 C 산화반응에 대한 단백질의 공존효과)

  • Kim Mi-Ok;Jang Sang-Moon
    • The Korean Journal of Food And Nutrition
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    • v.17 no.3
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    • pp.294-301
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    • 2004
  • Effects of superoxide dismutase(SOD), catalase(CAT), and such other proteins as bovine serum albumin(BSA), ovalbumin, lysozyme, and v-globulin on the autoxidation rates of L-ascorbic acid(AsA) in the absence of heavy metal ions and in the presence of Fe(III) or Cu(II) ions in water were examined. AsA was dissolved in a ultra-refined water at a concentration of 50 ${\mu}$M and 5 ${\mu}$M Fe(III) or 0.1 ${\mu}$M Cu(II) were added, and a oxygen gas was bubbled through the solution at a flow rate of 200 ml/min at 35$^{\circ}C$. The amount of remaining AsA in the reaction mixture was determined by using a UV spectrophotometer(at 265 nm). It was found that the Cu(II) at a concentration of 0.1 ${\mu}$M had a more accelerated for the autoxidation of AsA than Fe(III) at 5 ${\mu}$M. Moreover, it was confirmed that the ratio of remaining AsA was significantly larger in the presence of SOD, CAT, BSA, ovalbumin, lysozyme, and v-globulin than in the absence of proteins. The stabilization of AsA by various proteins were confirmed during the autoxidation of AsA in the presence of Fe(III) or Cu(II) in water. It was suggested that the non-enzymatic effects of SOD, CAT and some other proteins might be involves in the stabilization of AsA.