• Parasites, Hosts and Diseases
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• 제57권1호
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• pp.61-67
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• 2019

Cystic echinococcosis (CE) in sheep is a hazardous zoonotic parasitic disease that is caused by Echinococcus granulosus (Eg). At present, serological test is an important diagnostic method for Eg infection in domestic animals. Here, a fusion protein Eg mefAg-1 harboring 8 dominant B-cell epitopes of Eg such as antigen B, tetraspanin 1, tetraspanin 6, reticulon and Eg95 was produced in E. coli and evaluated for CE in sheep by indirect ELISA. Eg mefAg-1 showed in ELISA a high sensitivity (93.41%) and specificity (99.31%), with a coincidence rate of 97.02%. Overall, it is suggested that the Eg mefAg-1 could be a potential antigen candidate for CE serodiagnosis in sheep.

• Geomechanics and Engineering
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• 제27권6호
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• pp.595-604
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• 2021

With the advantages of high permeability and strength, pervious concrete piles can be suitable for ground improvement with high water content and low bearing capacity. By comparing the strength and permeability of pervious concrete with different aggregate sizes (3-5 mm and 4-6 mm) and porosities (20%, 25%, 30% and 35%), the recommended aggregate size (3-5 mm) and porosity (30%) can be achieved. The model tests of the pervious concrete piles in soft soil (silt and clay) foundations were conducted to evaluate the bearing characteristics, results show that, for the higher consolidation efficiency of the silty foundation, the bearing capacity of the silty foundation is 16% higher, and the pile-soil stress ratio is smaller. But when it is the ultimate load for the piles, they will penetrate into the underlying layer, which reduces the pile-soil stress ratios. With higher skin friction of the pile in the silty foundation, the pile penetration is smaller, so the decrease of the pile axial force can be less. For the difference in consolidation efficiency, the skin friction of pile in silt is more affected by the effective stress of soil, while the skin friction of pile in clay is more affected by the lateral stress. When the load reaches 4400 N, the skin friction of the pile in the silty foundation is about 35% higher than that of the clay foundation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권2호
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• pp.353-368
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• 2023

The four wing unmanned aerial vehicle owns the characteristics of small size, light weight, convenient operation and well stability. But it is easily disturbed by external environmental factors during flight with these disadvantages of short endurance and poor attitude solving ability. For solving these problems, a microprocessor based on STM32 chip is designed and the overall development is completed by the resources such as built-in timer and multi-function mode general-purpose input/output provided by the master micro controller unit, together with radio receiver, attitude meter, barometer, electronic speed control and other devices. The unmanned aerial vehicle can be remotely controlled and send radio waves to its corresponding receiver, control the analog level change of its corresponding channel pins. The master control chip can analyze and process the data to send multiple sets pulse signals of pulse width modulation to each electronic speed control. Then the electronic speed control will transform different pulse signals into different sizes of current value to drive the motor located in each direction of the frame to generate different rotational speed and generate lift force. To control the body of the unmanned aerial vehicle, so as to achieve the operator's requirements for attitude control, the PID controller based on Kalman filter is used to achieve quick response time and control accuracy. Test results show that the design is feasible.

• Earthquakes and Structures
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• 제25권2호
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• pp.113-123
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• 2023

A novel type of buckling restrained brace with built-up angle steel was developed. The core segment was formed by welding angle steel, and the middle section was reduced by cutting technology to solve the problem that the end of BRB was easy to buckle. The experimental program has been undertaken to study the performance of BRBs with different unbonded materials (silica gel, kraft paper) and different filler materials (ordinary concrete, full light-weight concrete). Four specimens were designed and fabricated for low cycle reciprocating load tests to simulate horizontal seismic action. The failure mode, hysteretic curves, tension-compression unbalance coefficient and other mechanical parameters were compared and analyzed. The finite element software ABAQUS was used to conduct numerical simulation, and the simulation results were compared with the experimental phenomena. The test results indicated that the hysteretic curve of each specimen was plump. Sustaining cumulative strains of each specimen was greater than the minimum value of 200 required by the code, which indicated the ductility of BRB was relatively good. The energy dissipation coefficient of the specimen with silica gel as unbonded material was about 13% higher than that with kraft paper. The experimental results were in good agreement with the simulation results.

• 한국지구과학회지
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• 제39권2호
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• pp.193-207
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• 2018

본 연구의 목적은 우리나라에서 수행된 지구과학교육 분야의 개념변화 연구 동향을 분석하여 향후 개념변화 연구의 기초 자료로 제공하는 것이다. 우리나라 지구과학 개념변화 연구의 경향성을 논문의 키워드, 발표 연도, 논문 출처, 연구 목적, 연구 대상, 연구 영역, 연구 방법 측면에서 분석하였다. 연구 대상은 우리나라 지구과학교육의 개념변화연구 논문이 처음 발표된 1989년부터 2017년 7월까지, 총 126편의 지구과학교육의 개념변화 논문이었다. 본 연구의 분석 결과는 다음과 같다. 첫째, 지구과학 개념변화 논문은 '개념변화'라는 용어를 '오개념', '선개념' 보다 더 많이 사용하였다. 둘째, 개념변화 논문은 2000년대에 많은 양적인 성장을 이루었다. 셋째, 개념변화는 석사 학위의 연구주제로 많이 이루어지고 있었다. 넷째, 오개념 조사와 그에 따른 교정을 함께 다룬 연구가 많았고, 오개념 조사로는 자유응답 검사법을, 오개념 교정 방법으로는 인지갈등 수업모형과 CAI 교수전략을 주로 활용하였다. 다섯째, 초등학생 대상 연구가 가장 많이 이루어졌다. 여섯째, 개념변화 연구의 지구과학 영역은 천문과 대기의 비중이 높았다. 마지막으로, 연구 초기에는 양적 분석 방법을 많이 사용하였지만, 2010년대에 들어서는 질적 분석 방법을 많이 사용하였다. 향후 개념변화의 연구 과제로 예비 및 현직 교사 대상의 개념변화 연구, 지질 해양 대기 등 다양한 영역으로의 연구 확대, 오개념 형성원인 파악 및 정의적 요인에 관한 연구 등을 제안하였다.

• 대한간호학회지
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• 제30권4호
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• pp.1055-1065
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• 2000

The purpose of this study was to develop, through the integration of instructional theory, a Courseware and to investigate the effectiveness of a web-based computer assisted instruction(WBI) program for preventing drug abuse, a serious problem for youth problem. During the first stage of this study done "Drug Abuse Prevention" Courseware was developed based on, Gagn & Brigg's instructional design theory, Keller's ARCS theory and the CAI model of Hannafin & Peck. For the second stage, the courseware was used to provide education for students adolescents in drug abuse prevention. This study used an quasi-experimental, one-group pretest-posttest design with a convenience sample of 36 male high school students who were at one high school located in Seoul. Data were collected using self-reported questionnaires which included a learning achievement tool, the Keller's IMMS (Instructional Material Motivation Survey), on attitudes to drug use, and on responses to the WBI instruction. Prior to the experiment, the "drug abuse prevention" learning method and the procedures of the study were explained to the students, and then the learning achievement of the subjects was measured as a pretest. The students were then given 2 weeks WBI utilizing the courseware. A post-test which included the pre-test learning achievement questionnaire and a survey of learning motivation and attitudes toward drug were given two weeks after the education was completed. The data analysis was done using SPSS/PC. Paired t-test was used to analyze the differences between the pre-test and post-test scores for learning achievement. The results of the analysis are as follows: There were significant differences in learning achievement between the pre-test and post-test(t=-18.62, p=0.000). The hypothesis, that learning achievement will be higher, after the class has used the courseware, than before was supported. The scores for learning motivation and attitudes toward drugs were also higher than the results of existing studies. In conclusion, this study suggests that WBI is an effective learning method in the prevention of drug abuse for adolescents as it can be used for self-learning and repeated learning as assisted instruction. Recommendation would be given that further research needs to be develped in the courseware by cognitive learning style and by multimedia courseware and virtual reality system.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4759-4763
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• 2013

Background: Prognostic factors of postoperative early and late recurrence in patients with hepatocellular carcinoma (HCC) undergoing curative resection remain to be clarified. The aim of this study was to identify risk factors for postoperative early (${\leq}$ 2 year) and late (> 2 year) intrahepatic recurrences in patients with single HCCs without macrovascular invasion. Methods: A total of 280 patients from December 2004 to December 2007 were retrospectively included in this study. Intrahepatic recurrence was classified into early (${\leq}$ 2 year) and late (> 2 year) and the Chi-Square test or Fisher's exact test and multivariate logistic regression analysis were performed to determine significant risk factors. Results: During the follow-up, 124 patients had intrahepatic recurrence, early and late in 82 and 42 patients, respectively. Multivariate logistic regression analysis showed that microvascular invasion (p=0.006, HR: 2.397, 95% CI: 1.290-4.451) was the only independent risk factor for early recurrence, while being female (p = 0.031, HR: 0.326, 95% CI: 0.118-0.901), and having a high degree of cirrhosis (P=0.001, HR: 2.483, 95% CI: 1.417-4.349) were independent risk factors for late recurrence. Conclusions: Early and late recurrence of HCC is linked to different risk factors in patients with single HCC without macrovascular invasion. This results suggested different emphases of strategies for prevent of recurrence after curative resection, more active intervention including adjuvant therapy, anti-cirrhosis drugs and careful follow-up being necessary for patients with relevant risk factors.

• 복식문화연구
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• 제21권4호
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• pp.606-611
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• 2013

It has been reported that tight sportswear could have complicated influence on physiological function of human body. The purpose of this present study was to investigate the effect of wearing gradient compression tights (GCT) on muscle strength and EMG activity during repeated isokinetic muscle contractions. Four healthy male undergraduate students performed maximal voluntary isokinetic concentric muscle contractions on biomechanical test and training systems with GCT and loose pants as control (Cont) respectively. During each test, the peak torque of extensor and flexor contractions and the surface electromyography (sEMG) of the rectus femoris and medial gastrocnemius was recorded simultaneously, the peak torque was recorded as an indicator of muscle strength, and the average amplitude and mean power frequency of sEMG were calculated as indicators of EMG activity. The results showed that: the peak torque decreased gradually during continuous muscle contractions both when the Cont and GCT were worn, average sEMG and mean power frequency declined along with the repetitions of muscle contractions for both wearing conditions, and the change tendency was consistence with that of peak torque. There was no obvious difference between the peak torque recorded wearing the Cont or wearing GCT, but when GCT were worn, average sEMG was lower and mean power frequency was higher than the Cont condition. In 24 samples obtained from four subjects, 80% of results showed the same trend. So we could make a conclusion that wearing GCT had no obvious effect on the improvement of muscle strength, but it would affect the EMG activity positivly.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권12호
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• pp.5785-5804
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• 2019

The information of localization is a fundamental requirement in wireless sensor network (WSN). The method of distance vector-hop (DV-Hop), a range-free localization algorithm, can locate the ordinary nodes by utilizing the connectivity and multi-hop transmission. However, the error of the estimated distance between the beacon nodes and ordinary nodes is too large. In order to enhance the positioning precision of DV-Hop, fast triangle flip bat algorithm, which is based on curve strategy and rank transformation (FTBA-TCR) is proposed. The rank is introduced to directly select individuals in the population of each generation, which arranges all individuals according to their merits and a threshold is set to get the better solution. To test the algorithm performance, the CEC2013 test suite is used to check out the algorithm's performance. Meanwhile, there are four other algorithms are compared with the proposed algorithm. The results show that our algorithm is greater than other algorithms. And this algorithm is used to enhance the performance of DV-Hop algorithm. The results show that the proposed algorithm receives the lower average localization error and the best performance by comparing with the other algorithms.

• Journal of Acupuncture Research
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• 제22권1호
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• pp.117-130
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• 2005

소요산(逍遙散) 약침(藥針)이 흰쥐의 갱년기(更年期) 우울증(憂鬱症) 및 stress모델의 인지, 학습 및 기억장애와 불안행동에 미치는 효능(效能)을 파악하기 위하여 행동실험 학적 검사와 면역조직화학적 검사를 실시한 결과 다음과 같은 결론을 얻었다. 1. Morris water maze의 학습검사결과 Soyo-san군(群)의 경우, 시간단축이 현저하게 나타나서 제 6일째 $24.69{\pm}8.48$초로 측정되어 Ovx군(群)에 대해 유의성 있는 인지 및 학습력을 보였다. 2. Morris water maze의 기억검사결과 Soyo-san군(群)이 $3.38{\pm}0.82$로 Sham군(群)과 Ovx군(群)에 대해 머문 시간이 유의성있게 증가하였다. 3. Ventral tegmental area의 TH의 발현정도는 Normal군(群)이 $9.14{\pm}0.50$, Sham군(群)은 $9.00{\pm}0.29$, Ovx군(群)은 $10.81{\pm}0.63$, Soyo-san군(群)은 $8.19{\pm}0.42$로 나타났는데 Soyo-san군(群)이 Ovx에 대해 유의성있게 감소하였다. 4. Hippocampus의 CAI부위에서는 ChAT 발현 정도에서 Soyo-san군(群)이 On군(群)에 대해서 유의하게 증가하였다. 이상(以上)의 결과를 종합하면 소요산(逍遙散) 약침(藥針)이 난소 적출 흰쥐의 stress모델의 인지, 학습 및 기억장애를 호전시키는 것으로 나타났으며 이는 갱년기(更年期) 여성(女性)의 우울증(憂鬱症) 및 stress 반응에 대한 적절한 치료제로서 가능하리라 사료된다.