• Journal of Internet Computing and Services
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• v.9 no.1
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• pp.21-32
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• 2008

In this paper, we propose new modulation schemes using the conventional CACB (Constant Amplitude Coded Multicode Biorthogonal) modulation with constant amplitude property. Also the proposed modulation schemes supports high transmission data rate by increasing the spectral efficiency, In order to obtain the high spectral efficiency, the $Q^2$AM (Quadrature-Quadrature Amplitude Modulation) and CA-$Q^2$AM (Constant Amplitude-$Q^2$AM) are used. We explain the simplest combining modulation scheme of CACB and $Q^2$AM (i.e., CACB-$Q^2$AM). However, this modulation scheme cannot support the constant amplitude property. Hence the first CACB-CA-$Q^2$AM (or CACB-CA-$Q^2$AM I) modulation scheme is proposed for the constant amplitude property. In the modulation scheme, the redundant constant amplitude encoding (spectral efficiency decrease) is required. Therefore, the second CACB-CA-$Q^2$AM (or CACB-CA-$Q^2$AM II) modulation scheme is proposed retaining the constant amplitude and the spectral efficiency. Computer simulations show that the proposed CACB-CA-$Q^2$AM II is the efficient modulation scheme.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.1
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• pp.93-99
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• 2008

In this paper, we propose new modulation schemes using the conventional CACB modulation with constant amplitude property. Also the proposed modulation schemes supports high transmission data rate by increasing the spectral efficiency. In order to obtain the high spectral efficiency, the $Q^2$PSK and CA-$Q^2$PSK are used. We explain the simplest combining modulation scheme of CACB and $Q^2$PSK (i.e., CACB-$Q^2$PSK). However, this modulation scheme cannot support the constant amplitude property. Hence the first CACB-CA-$Q^2$PSK (or CACB-CA-$Q^2$PSK I) modulation scheme is proposed for the constant amplitude property. In the modulation scheme, the redundant constant amplitude encoding (spectral efficiency decrease) is required. Therefore, the second CACB-CA-$Q^2$PSK (or CACB-CA-$Q^2$PSK II) modulation scheme is proposed retaining the constant amplitude and the spectral efficiency. Computer simulations show that the proposed CACB-CA-$Q^2$PSK II is the efficient modulation scheme.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.5
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• pp.481-491
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• 2023

The β subunits of high voltage-gated calcium channels (HGCCs) are essential for optimal channel functions such as channel gating, activation-inactivation kinetics, and trafficking to the membrane. In this study, we report for the first time the potent blood pressure-reducing effects of peptide fragments derived from the β subunits in anesthetized and non-anesthetized rats. Intravenous administration of 16-mer peptide fragments derived from the interacting regions of the β1 [cacb1(344-359)], β2 [cacb2(392-407)], β3 [cacb3(292-307)], and β4 [cacb4(333-348)] subunits with the main α-subunit of HGCC decreased arterial blood pressure in a dose-dependent manner for 5-8 min in anesthetized rats. In contrast, the peptides had no effect on the peak amplitudes of voltage-activated Ca²⁺ current upon their intracellular application into the acutely isolated trigeminal ganglion neurons. Further, a single mutated peptide of cacb1(344-359)-cacb1(344-359)_K357R-showed consistent and potent effects and was crippled by a two-amino acid-truncation at the N-terminal or C-terminal end. By conjugating palmitic acid with the second amino acid (lysine) of cacb1(344-359)_K357R (named K2-palm), we extended the blood pressure reduction to several hours without losing potency. This prolonged effect on the arterial blood pressure was also observed in non-anesthetized rats. On the other hand, the intrathecal administration of acetylated and amidated cacb1(344-359)_K357R peptide did not change acute nociceptive responses induced by the intradermal formalin injection in the plantar surface of rat hindpaw. Overall, these findings will be useful for developing antihypertensives.

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 2004.11a
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• pp.346-346
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• 2004

• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.2
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• pp.343-351
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• 2008

In this paper, we investigate the design of the QAM(Quadrature Amplitude Modulation) method for the CACB(Constant Amplitude Coded Multicode Biorthogonal) scheme. The modulation method fan improve the transmission data rate by increasing the BE(Bandwidth Efficiency). Additionally, we can improve the system performance by using the QAM SD(Soft Decision) method with the MDSA(Minimum Distance Selection Algorithm). Finally, the DFE(Decision Feedback Equalizer) for the CACB-QAM is simulated under the MPF(MultiPath Fading) channel for real implementation. The proposed scheme can be used for the PHY(PHYsical layer) standard of the WPAN(Wireless Personal Area Network) requiring high rate data transmission.

• Journal of The Institute of Information and Telecommunication Facilities Engineering
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• v.4 no.1
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• pp.37-44
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• 2005

본 논문에서는 멀티 코드 CDMA(Code Division Multiple Access)시스템에서 고속의 멀티미디어 서비스를 지원하기 위해 정보 데이터열을 QAM(Quadrature Amplitude Modulation) 부호화하는 방법을 제안한다. 송신 구조는 입력 비트를 정진폭 다중부호 이진직교 변조(Constant amplitude code biorthogonal modulation: 이하 CACB라 칭함)로 부호화하여 전송 심볼의 크기를 일정하게 하고 이렇게 이진화된 신호를 QAM 부호화하여 전송속도를 높인다. 복조기의 구조는 수신된 신호로부터 QAM 연판정기 블록을 거쳐 생성된 신호를 CACB 복호화기를 거쳐 데이터를 복조해 낸다. 제안된 시스템은 기존의 멀티 코드 방식에 비해 대역폭 효율을 크게 개선시킬 수 있어 전송 속도를 많이 향상시킬 수 있고, 멀티 코드 방식을 기반으로 하기 때문에 디지털 가전기기나 3세대 이동통신과, WPAN과 관련된 무선 네트워크 응용과 같은 미래의 고속의 무선 멀티미디어 서비스를 지원하기에 적합하다.

• The Korean Journal of Pain
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• v.32 no.1
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• pp.30-38
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• 2019

Background: The adductor canal block (ACB) is an effective intervention for postoperative analgesia following total knee arthroplasty (TKA). However, the ideal ACB regimen has not yet been established. We compared the analgesic effects between a continuous ACB group and fentanyl-based intravenous patient-controlled analgesia (IV-PCA) with a single-shot ACB group. Methods: Patients who underwent TKA were randomly allocated to either a continuous ACB group (Group CACB) or IV-PCA with a single-shot ACB group (Group IVACB). Before the surgery, ultrasound guided ACB with 0.5% ropivacaine 20 cc was provided to all patients. Before skin incision, the infusion system (0.2% ropivacaine through an adductor canal catheter in group CACB vs. intravenous fentanyl in group IVACB) was connected. The postoperative pain severity; the side effects of local anesthetics and opioids; administration of rescue analgesics and anti-emetics; and sensorimotor deficits were measured. Results: Postoperative pain severity was significantly higher in the IVACB group at 30 min, 4 h, 24 h, and 48 h after surgery. The averages and standard deviations (SD) of the NRS score of postoperative pain were $0.14{\pm}0.37$, $4.57{\pm}2.37$, $6.00{\pm}1.63$, and $4.28{\pm}1.49$, respectively in the IVACB group. Rescue analgesic requirements and quadriceps muscle strength were not statistically different between the groups throughout the postoperative period. Moreover, rescue antiemetic requirements were higher in group IVACB than group CACB. Conclusions: In this study, the continuous ACB provided superior analgesia and fewer side effects without any significant motor deficit than the IV-PCA with a single-shot ACB.

• Journal of the Korean Orthopaedic Association
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• v.54 no.5
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• pp.411-417
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• 2019

Purpose: To compare the clinical outcomes of single injection adductor canal block (SACB), continuous adductor canal block (CACB), and the concomitant use of transdermal buprenorphine after total knee arthroplasty (TKA). Materials and Methods: A total of 125 patients who underwent TKA were divided into three groups and the clinical results were retrospecitively compared. Group I was comprised of patients with pain controlled by SACB (n=41). Group II consisted of patients with pain controlled by both SACB and transdermal buprenorphine (10 ㎍/h) (n=44). Group III contained patients with pain controlled by CACB (n=40). The visual analogue scale (VAS) was used as the pain control indicator and the patients were measured on a VAS for resting on the bed (VAS-Rest) at 12 hours, 24 hours, and 48 hours after surgery. The VAS while doing continuous passive motion (VAS-CPM) on the first and second postoperative day was also measured. In addition, the total amount of medications used (Butopahn, Tridol, and Ketorac) for the intravenous patient controlled analgesia (PCA) was counted for 48 hours after surgery. As the indicator of the functional recovery outcome, the incidence of nausea and vomiting was observed for 48 hours after surgery. The maximum knee joint flexion range and maximum walking distance on the first and second postoperative day, and the total length of stay at the hospital were compared. Results: The VAS-Rest was similar in the three groups at 12 hours after surgery, but at 24 hours and 48 hours after surgery, group II and III a lower VAS-CPM and total amount of medications used for PCA than group I (p<0.05). The three groups showed a low incidence of nausea and vomiting, maximum knee joint flexion range, and similar walking distance and total length of stay at the hospital. Conclusion: The combination of SACB and transdermal buprenorphine has great pain control effect initially. On the other hand, it is not associated with catheter complications and it is convenient to use and safety toward the renal function. Therefore, the concomitant use of SACB and transdermal buprenorphine can be an effective pain control method after TKA.