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Associations between dietary patterns and hypertension among Korean adults: the Korean National Health and Nutrition Examination Survey (2008-2010)

  • Shin, Ji-Ye;Kim, Ji-Myung;Kim, Yuri
    • Nutrition Research and Practice
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    • v.7 no.3
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    • pp.224-232
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    • 2013
  • The objective of this study is to identify the dietary patterns associated with the risk of hypertensions among Korean adults using data from the Korean National Health and Nutrition Examination Survey (KNHANES, 2008-2010). This study analyzes data from 11,883 subjects who participated in the health and nutrition survey, aging from 20 to 64 years. We performed factor analysis based on the weekly mean intake frequencies of 36 food groups to identify major dietary patterns. We identified three major dietary patterns in both sexes, namely "traditional", "western" and "dairy and carbohydrate" patterns. Participants in the highest quartile of western pattern scores had significantly higher blood pressure, serum total cholesterol, and triglyceride levels than those in the lowest quartile. Although not statistically significant, a trend (P for trend = 0.0732) toward a positive association between the western dietary pattern and hypertension risk was observed after adjustments for age, sex, education, income, body mass index (BMI), smoking, physical activity, and energy intake. The dairy and carbohydrate pattern was inversely related with BMI and blood pressures and positively associated with serum high-density lipoprotein (HDL)-cholesterol. After adjusting the age, sex, education, income, BMI, smoking, physical activity and energy intake, the dairy and carbohydrate pattern showed inverse associations with hypertension prevalence (OR = 0.64, 95% CI = 0.55-0.75; P for trend < 0.0001). Intakes of fiber, sodium, and antioxidant vitamins were significantly higher in the top quartile for the traditional pattern than in the lowest quartile for the traditional pattern (P for trend < 0.0001). Intakes of fiber (P for trend < 0.0001), calcium (P for trend < 0.0001), retinol (P for trend = 0.0164), vitamin $B_1$ (P for trend = 0.001), vitamin $B_2$ (P for trend < 0.0001), niacin (P for trend = 0.0025), and vitamin C (P for trend < 0.0001) were significantly increased across quartiles for the dairy and carbohydrate pattern whereas sodium (P for trend < 0.0001) intake was decreased for this pattern. In conclusion, the dairy and carbohydrate pattern may be associated with a reduced risk of hypertension whereas the western pattern may be associated with an increased risk of hypertension among Korean adults.

Robust Maneuvering Target Tracking Applying the Concept of Multiple Model Filter and the Fusion of Multi-Sensor (다중센서 융합 및 다수모델 필터 개념을 적용한 강인한 기동물체 추적)

  • Hyun, Dae-Hwan;Yoon, Hee-Byung
    • Journal of Intelligence and Information Systems
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    • v.15 no.1
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    • pp.51-64
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    • 2009
  • A location tracking sensor such as GPS, INS, Radar, and optical equipments is used in tracking Maneuvering Targets with a multi-sensor, and such systems are used to track, detect, and control UAV, guided missile, and spaceship. Until now, Most of the studies related to tracking Maneuvering Targets are on fusing multiple Radars, or adding a supplementary sensor to INS and GPS. However, A study is required to change the degree of application in fusions since the system property and error property are different from sensors. In this paper, we perform the error analysis of the sensor properties by adding a ground radar to GPS and INS for improving the tracking performance by multi-sensor fusion, and suggest the tracking algorithm that improves the precision and stability by changing the sensor probability of each sensor according to the error. For evaluation, we extract the altitude values in a simulation for the trajectory of UAV and apply the suggested algorithm to carry out the performance analysis. In this study, we change the weight of the evaluated values according to the degree of error between the navigation information of each sensor to improve the precision of navigation information, and made it possible to have a strong tracking which is not affected by external purposed environmental change and disturbance.

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A Single Nucleotide Deletion resulting in Frameshift in Two Korean Neonates with Thyroxine-Binding Globulin Deficiency (단일 뉴클레오타이드 결손으로 인한 Frameshift 돌연변이로 규명된 티록신결합글로불린 결핍증 1례)

  • Park, Sang-Joon;Suh, Jin-Soon;Jung, Min-Ho;Lee, Hee-Jin;Suh, Byung-Kyu;Lee, Won-Bae;Lee, Byung-Churl
    • Clinical and Experimental Pediatrics
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    • v.48 no.11
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    • pp.1252-1255
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    • 2005
  • Abnormalities in the levels of thyroxine-binding globulin (TBG) are not associated with clinical disease and they do not require treatment. Congenital TBG deficiency is inherited in an X-linked manner. To date, some complete and partial TBG variants and one polymorphism have been identified by analysis of the TBG gene. Two male neonates were referred to us because of their low $T_4$ levels that were noted on the neonatal screening test. They showed normal levels of free $T_4$ and TSH. Their serum TBG was not detectable and those values of their parents were within the normal ranges. The genomic DNA was extracted from their white blood cells and the four coding exons of the TBG gene were amplified by using polymerase chain reaction. Sequencing of the four coding regions and all the intron/exon junctions revealed a single nucleotide deletion of the first base of the codon 352 of the mature protein in both of the neonates. This mutation resulted in a frameshift and a premature stop codon (TGA) 374. Their mothers were shown to be heterozygotes. We detected a single nucleotide deletion resulting in a frameshift in two male Korean neonates who had complete TBG deficiency.

출토(出土) 조선시대(朝鮮時代) 유의(遺衣)의 복식사적(服飾史的) 연구(硏究)

  • Kim, Dong-Uk;Go, Bok-Nam
    • Journal of the Korean Society of Costume
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    • v.2
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    • pp.9-21
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    • 1978
  • The object of this article is to examine the shapes and the development of the costume worn in the early and middle Yi Dynasty from the viewpoint of the history of customes with the excavated clothing from Chung-Ju (1530 A.D.), Wool-San (1650 A.D.), An-Dong (1650 A.D.) etc. The study of the history of costumes of the early years of the Yi Dynasty has been mainly dependent upon fiblirographical records sofar. So I have arranged in order some excavated clothing of the early Yi Dynasty, which gives us some means for the study of Korean historical costumes. It is noticeably remarkable that the daily wear of the early Yi Dynasty period was excavated for the first time from Chung-ju. The results drawn from this research are: It is argued that the original from of Chul-nik(天翼) has been excavated. This is the remnants Mongolian clothing of the Koryo Dynasty, and it is sketched in the Dai-Myong-jib-lei(大明集禮) as Yo-sun-o-ja which the lower classes usually put on. The similar clothing is also handed down as a Dan-po(緞袍) from the ming Dynasty, and we can presume that Chul-nik was a common clothing regardless of the social status of their wearer. It is also remarkable that even women at those times wore the Chul-nik. The length of the Cheo-go-ri of the early Yi Dynasty was the middle hip length, and the edge of the sleeves was very wide which called Cham-soo, and it was handed down to the middle period of the Yi Dynasty which can be seen in the coat (po) of women(直領袍). The systems of the straight-collar Po(袍) during the early Yi Dynasty were discovered for the first time. This Po(袍) which would represent the po-system of the early years of Yi Dynasty, is handed down even to the middle of Yi Dynasty. The collars of the Po(coat) of the early Yi Dynasty are mostly double collars(二重衿) and these give us the advantage in reconsidering of the cheo-go-ri(赤古里) of the Kingdom of Shin-la, or Koryo Dynasty. The edge of the women's Ba-ji(袴) of the early Yi Dynasty was wide and the Ba-ji had a shoulder belt which connect the front part with the back one, which showed the practical point of Ba-ji. The men's Ba-ji of the middle Yi Dynasty was the same as can be seen today and it is clear that the Mongolian Ba-ji dated to B.C. 1 was the same one also. In the system of the Chi-ma(常), there seems to be no differences between the ancient styles and those of these times.

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Effects of Freshwater Flooding on the Properties of the Accelerated Thermally Aged CSPE (가속열화 된 CSPE의 특성에 미치는 담수침지의 영향)

  • Kang, Myeong-Gyun;Lee, Jung-Hoon;Lee, Seung-Hoon;Jeon, Jun-Soo;Kim, In-Yong;Shin, Yong-Deok
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.63 no.3
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    • pp.367-370
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    • 2014
  • The accelerated thermal aging of a CSPE were carried out for 0, 80.82, 161.63 days at $100^{\circ}C$, which are equal to 0, 40 and 80 years, respectively. The volume electrical resistivities of the non-accelerated thermally aged CSPE and the accelerated thermally aged CSPE for 40y and 80y were $9.620{\times}10^{12}{\sim}1.246{\times}10^{13}{\Omega}{\cdot}cm$, $5.066{\times}10^{12}{\sim}7.576{\times}10^{12}{\Omega}{\cdot}cm$ and $7.195{\times}10^{12}{\sim}9.208{\times}10^{12}{\Omega}{\cdot}cm$ at room temperature, respectively. The dielectric constant of the non-accelerated thermally aged CSPE and the accelerated thermally aged CSPE for 40y and 80y were 3.355~4.030, 2.996~3.963 and 3.020~4.776 at room temperature, respectively. After seawater and freshwater flooding, the volume electrical resistivity of the CSPE trend slightly upward according to drying day at room temperature. After seawater flooding, the dielectric constant of the accelerated thermally aged CSPE were not measured. After seawater flooding, bright open pores of the accelerated thermally aged CSPE were partly transferred to dark close pores due to salinity. After freshwater flooding, dark close pores of the accelerated thermally aged CSPE were partly transferred to bright open pores because salinity of them is decreased. An insulation property of a cable in NPPs was decreased because of the seawater flooding, and an insulation property of them was recovered through the freshwater flooding. As a result, it is considered that an insulation property of a contaminated cable through Tsunami can be recovered if it is cleaned quickly.

Snoring Detection using Polyvinylidene Fluoride Vibration Sensors (Polyvinylidene Fluoride 진동센서를 이용한 코골이 검출)

  • Jee, Duk-Keun;Wei, Ran;Kim, Hee-Sun;Im, Jae-Joong
    • Science of Emotion and Sensibility
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    • v.14 no.3
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    • pp.459-466
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    • 2011
  • Sleep diseases such as snoring and sleep apnea are physically, mentally harmful and results serious health problems. Snoring, known as breathing noise, is caused by coupled oscillation of the airway when the air passes through the trachea, and sleep apnea is caused by upper airway blockage. In order to solve these problems, many attempts have been made to detect the snoring during sleep and alleviate it. In this study, a new sensing system and analysis algorithm were developed in order to detect snoring sounds correctly under various sleep environments. Two polyvinylidene fluoride (PVDF) vibration sensors were used inside the pillow. The first PVDF sensor detects vibration transmitted through skull caused by snoring. And the second PVDF sensor detects both snoring sounds and ambient noises. The signals of two sensors were acquired through the designed analog circuits, and analyzed for snoring detection. Ten volunteers were participated for the experiment under five different conditions. Data from two PVDF sensors were processed by the established analysis algorithm, and snoring sounds were compared to noises. The results indicated that the energy of snoring is 70% bigger than that of ambient noise, which proves effectiveness of sensing system and analysis algorithm. Further study would be continued for more wide clinical studies with various environment noises. Based on this study, development of anti-snore pillow and sleep monitoring system for comfort sleep could be developed.

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Effect of System Parameters on Target Parameters in Extrusion Cooking of Corn Grit by Twin-Screw Extruder (옥분 압출가공시 이축압출성형기의 System Parameters에 따른 압출물의 특성변화)

  • Kim, Ji-Yong;Kim, Chong-Tai;Kim, Chul-Jin
    • Korean Journal of Food Science and Technology
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    • v.23 no.1
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    • pp.88-92
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    • 1991
  • To analyze the effects of the system parameters on the target parameters, which include the amount of water evaporation, water solubility index(WSI) and water absorption index(WAI), test trials of fractional factorial design of the three process variables at three levels were carried out for corn grit with a laboratory twin-screw extruder with three different screw configurations. The system parameters collected from the trials, such as extrusion temperature, specific mechanical energy input(SME) and mean residence time(RT), were showed the ranges of $129{\sim}182^{\circ}C$, $67{\sim}163\;kwh/ton$ and $12{\sim}34\;sec$, respectively. Within these ranges of the system parameters, the target parameters were able to be quantified by using multiple regression equations. The correlation of results with the system parameters blocked by the screw configuration as dependent variables, yield correlation coefficients above 0.90, and the correlation using the system parameters obtained from whole experiment system as the dependent variables yield correlation coefficients around 0.80. The functional relationship, which can be quantified by second order polynomial regression equation with only two system parameters within necessary degree of accuracy, can he graped in three dimensional surface response and contour diagrams.

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Genome-wide Association Study to Identify Quantitative Trait Loci for Meat and Carcass Quality Traits in Berkshire

  • Iqbal, Asif;Kim, You-Sam;Kang, Jun-Mo;Lee, Yun-Mi;Rai, Rajani;Jung, Jong-Hyun;Oh, Dong-Yup;Nam, Ki-Chang;Lee, Hak-Kyo;Kim, Jong-Joo
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.11
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    • pp.1537-1544
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    • 2015
  • Meat and carcass quality attributes are of crucial importance influencing consumer preference and profitability in the pork industry. A set of 400 Berkshire pigs were collected from Dasan breeding farm, Namwon, Chonbuk province, Korea that were born between 2012 and 2013. To perform genome wide association studies (GWAS), eleven meat and carcass quality traits were considered, including carcass weight, backfat thickness, pH value after 24 hours (pH24), Commission Internationale de l'Eclairage lightness in meat color (CIE L), redness in meat color (CIE a), yellowness in meat color (CIE b), filtering, drip loss, heat loss, shear force and marbling score. All of the 400 animals were genotyped with the Porcine 62K SNP BeadChips (Illumina Inc., USA). A SAS general linear model procedure (SAS version 9.2) was used to pre-adjust the animal phenotypes before GWAS with sire and sex effects as fixed effects and slaughter age as a covariate. After fitting the fixed and covariate factors in the model, the residuals of the phenotype regressed on additive effects of each single nucleotide polymorphism (SNP) under a linear regression model (PLINK version 1.07). The significant SNPs after permutation testing at a chromosome-wise level were subjected to stepwise regression analysis to determine the best set of SNP markers. A total of 55 significant (p<0.05) SNPs or quantitative trait loci (QTL) were detected on various chromosomes. The QTLs explained from 5.06% to 8.28% of the total phenotypic variation of the traits. Some QTLs with pleiotropic effect were also identified. A pair of significant QTL for pH24 was also found to affect both CIE L and drip loss percentage. The significant QTL after characterization of the functional candidate genes on the QTL or around the QTL region may be effectively and efficiently used in marker assisted selection to achieve enhanced genetic improvement of the trait considered.

Marine Environments in the Neighborhood of the Narodo as the First Outbreak Region of Cochlodinium polykrikoides Blooms (Cochlodinium polykrikoides 적조의 최초발생해역인 나로도 주변 해역의 해양환경)

  • Lee, Moon-Ock;Moon, Jin-Han
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.11 no.3
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    • pp.113-123
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    • 2008
  • We have analyzed a long term data of marine environments, red tide information and meteorology acquired by NFRDI and KMA, in order to understand the characteristics of marine environments in the Narodo coastal waters which is known to be the first outbreak region of Cochlodinium polykrikoides blooms. During the period of from 1992 to 2007, Cochlodinium polykrikoides blooms have first occurred more often in August. However, the outbreak time of the blooms tended to be earlier annually, and in addition, the surface salinity also had a tendency to increase. Consequently, it suggested that there might be a relationship between the transition of the outbreak time of the blooms and salinity. On the other hand, insolation was relatively rich but precipitation was relatively scarce in Gohung Province, compared to Yeosu or Tongyeong, when Cochlodinium polykrikoides blooms first occur in Narodo coastal waters. Average water temperature and salinity in August in Narodo coastal waters were all higher than those in Gamak and Jinhae bays, suggesting that Narodo coastal waters are a region of relatively high water temperature and high salinity. Also, concentrations of nutrients and chlorophyll- a were significantly low than those in Jinhae Bay, which is known to be a eutrophicated region, while the overall water quality seemed to be similar to Gamak Bay. The results of PCA(Principal Component Analysis) proved that insolation and water temperature are the most important factors for the outbreak of Cochlodinium polykrikoides blooms in Narodo coastal waters while concentrations of COD and dissolved oxygen are secondly important. Furthermore, typhoons also appeared to be one of most important factors for the outbreak of Cochlodinium polykrikoides blooms.

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옻나무 유래 Flavonoid처리가 흰쥐 Leydig 세포의 체외배양에서 Testosterone분비에 미치는 영향

  • 성환후;최선호;민관식;장유민;나천수;정일정
    • Proceedings of the KSAR Conference
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    • 2001.03a
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    • pp.80-80
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    • 2001
  • 옻나무 유래 Flavonoid(F)는 항암 효과, 숙취해소 등의 효능이 있으며, 신장의 기능을 촉진하고 생식에도 영향을 준다고 알려져 있다. 그 주성분으로는 fustin, fisetin, sulfuretin, butein으로 추정되고 있다. 본 연구팀의 예비실험에서 성숙 흰쥐에게 F를 30일간 5mg씩 구강투여 하여 정소 중량 및 혈액 내 Testosterone 농도를 분석한 결과, 정소 중량이 증가되고 혈중 Testosterone의 농도도 대조구에 비해 유의적으로 높은 결과를 얻었다. 이에 본 연구의 목적은 옻나무 유래 F가 성숙 수컷 횐쥐의 생식 기능에 직접 미치는 영향을 알아보고자, 흰쥐 Leydig 세포를 분리, 회수하여 체외배양에서 Testosterone농도를 조사하였다. SD계 흰쥐(약 12주령, 체중 250g 전후)의 정소를 적출 한 후, Leydig 세포를 회수하기 위해 0.25% collagenase용액에 넣어 34$^{\circ}C$에서 15분간 진탕 수조에서 배양하였다. 배양된 정소조직은 D-MEM 배양액(10% FCS와 antibiotics 첨가)으로 2~3회 세척한 후 세포 수를 1$\times$$10^{6}$ cells/$m\ell$/well로 분주하여, F(20, 40, 80, 160ng), IGF-I(50, 100ng) 와 LH(10, 100ng) 용량별 각각 첨가하여 배양하였다. 각 처리 후, 배양시간(3, 6, 12, 24, 36시간)에 따라 배양액을 회수하여 COAT-A-COUNT(DPC, USA) kit를 이용하여 RIA방법에 의해 Testosterone을 분석한 결과는 다음과 같다. 대조구 Leydig 세포를 36시간까지 체외 배양하여 Testosterone의 농도를 조사한 결과, 24시간 배양구가 가장 높은 농도를 나타내었다. F를 단독 첨가하여 12시간 배양한 실험에서 F 80ng 첨가구에서 유의적으로 높은 농도를 보였다. LH 10ng 및 100ng 첨가구의 시간별 변화로는, LH 10ng 첨가구에서는 6~12시간 이후, LH 100ng 첨가구에서는 3~6시간 사이에서 유의적인 증가를 보였다. 또한, LH 10ng 첨가 실험에서는 LH 10ng+F 40ng에서 12시간 배양 시, 유의적으로 높은 Testosterone 분비를 확인하였으며, LH 100ng을 첨가하여 3시간 배양 시는 각 처리구 마다 높은 유의적 차이를 보였다. 한편, GH에 관여하는 IGF-I 첨가효과를 비교 검토한 결과, LH 100ng+IGF-I 100ng, 6시간 배양구에서 유의적으로 높게 나타내었다. 이상의 결과로, F 단독 처리 시의 적정량은 약 80ng이며, 흰쥐 정소 Leydig 세포의 Testosterone분비를 촉진하는 작용을 하는 것으로 사료되며, 특히 LH+F구에서 Testosterone분비를 더욱 향상시킴으로써 정소 Leydig 세포의 Androgen 생성을 촉진시키는 역할이 있는 것으로 보여진다 따라서 옻나무 유래 F는 포유동물의 생식기능에 중요하게 작용하는 것으로 사료된다.

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