• Title/Summary/Keyword: C-scanner

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Miniature Biochip Fluorescence Detection System with Spatial Separation of Fluorescence from Excitation Light (형광과 여기광을 공간적으로 분리하는 바이오칩용 소형 형광측정시스템)

  • Kim Ho-seong;Choi Jea-ho;Park Ju-han;Lee Kook-nyung;Kim Yong-Kweon
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.54 no.8
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    • pp.378-383
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    • 2005
  • We report the development of miniature fluorescence detection systems that employ miniature prism, mirrors and low coat CCD camera to detect the fluorescence emitted from 40 fluorescently-labeled protein patterns without scanner. This kind of miniature fluorescence detection system can be used in point of care. We introduce two systems, one uses prism+mirror block and the other uses prism and two mirrors. A large NA microscope eyepiece and low cost CCD camera are used. We fabricated protein chip containing multi-pattern BSA labeled with Cy5, using MEMS technology and modified the surface chemically to clean and to immobilize proteins. The measurements show that the combination of prism and mirrors can homogenize elliptical excitation light over the sample with higher optical efficiency, and increase the separation between excitation and fluorescence light at the CCD to give higher signal intensity and higher signal to noise ratio. The measurements also show that protein concentrations ranging from 10 ng/ml to 1000 ng/ml can be assayed with very small error. We believe that the proposed fluorescence detection system can be refined to build a commercially valuable hand-held or miniature detection device.

Development of Ultrasonic Inspection System and Application to Overlay Weld Flaw Detection (초음파 자동 검사시스템의 개발과 오버레이 용접부의 결함검사)

  • Nam, Young-Hyun;Seong, Un-Hak
    • Journal of the Korean Society for Nondestructive Testing
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    • v.20 no.6
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    • pp.562-567
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    • 2000
  • Many pressure vessels for power and industrial plant are fabricated from low alloy carbon steels. The inner sides of pressure vessels are commonly weld-cladded with austenitic stainless steels to minimize problems of corrosive attack. Disbonding cracks are often detected at the transition region of welding interlayer, which is serious problem to reliability of pressure vessels. We have developed C-scan system to high speed inspection of overlay weld using DSP(digital signal processor). This system consists of signal processing parts (oscilloscope, pulser/receiver, digitizer, DSP), scanner, program and position controller. The developed system has been applied to a practical ultrasonic testing in overlay weld, and demonstrated high speed with precision

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Comparison of different digital shade selection methodologies in terms of accuracy

  • Nursen Sahin;Cagri Ural
    • The Journal of Advanced Prosthodontics
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    • v.16 no.1
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    • pp.38-47
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    • 2024
  • PURPOSE. This study aims to evaluate the accuracy of different shade selection techniques and determine the matching success of crown restorations fabricated using digital shade selection techniques. MATERIALS AND METHODS. Teeth numbers 11 and 21 were prepared on a typodont model. For the #11 tooth, six different crowns were fabricated with randomly selected colors and set as the target crowns. The following four test groups were established: Group C, where the visual shade selection was performed using the Vita 3D Master Shade Guide and the group served as the control; Group Ph, where the shade selection was performed under the guidance of dental photography; Group S, where the shade selection was performed by measuring the target tooth color using a spectrophotometer; and Group I, where the shade selection was performed by scanning the test specimens and target crowns using an intraoral scanner. Based on the test groups, 24 crowns were fabricated using different shade selection techniques. The ΔE values were calculated according to the CIEDE2000 (2:1:1) formula. The collected data were analyzed by means of a one-way analysis of variance. RESULTS. For the four test groups (Groups C, Ph, S, and I), the following mean ΔE values were obtained: 2.74, 3.62, 2.13, and 3.5, respectively. No significant differences were found among the test groups. CONCLUSION. Although there was no statistically significant difference among the shade selection techniques, Group S had relatively lower ΔE values. Moreover, according to the test results, the spectrophotometer shade selection technique may provide more successful clinical results.

Extra Dose Measurement of Differential Slice Thickness of MVCT Image with Helical Tomotherapy (토모테라피 치료 시 MVCT Image의 Slice Thickness 차이에 따른 선량 비교)

  • Lee, Byungkoo;Kang, Suman
    • Journal of the Korean Society of Radiology
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    • v.7 no.2
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    • pp.145-149
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    • 2013
  • Helical Tomotherapy is an innovative means of delivering intensity modulated radiation therapy (IMRT) using a device that merges features of a linear accelerator and helical computed tomography (CT) scanner. Hereat, during helical tomotherapy process, megavoltage computed tomography (MVCT) image are usually used for guiding the precise set-up of patient before/after treatment delivery. But which would certainly increase the total dose for patients, this study was to investigate the imaging dose of MVCT using the cylindrical "Cheese" phantom on a tomotherapy machine. A set of cylindrical "Cheese" phantom was adopted for scanning with respectively pitch value (1, 2, 3 mm) with same number slice (10 slice), same length (approximately 9 cm) and phantom set-ups on the couch of tomotherapy system. The average MVCT imaging dose were measured using A1SL ion chamber inserted in the phantom with preset geometry. The MVCT scanning average dose for the cylindrical "Cheese" phantom was 2.24 cGy, 1.02 cGy, 0.81 cGy during respectively pitch value (pitch 1, 2, 3 mm) with same number slice (10 slice), and same length's average dose was 2.47 cGy, 1.28 cGy, 0.88 cGy respectively (pitch 1, 2, 3 mm). Two major parameters, the assigned pitch numbers and scanning length, where the most important impacts to the dose variation. The MVCT dose was inversely proportional to the CT pitch value. The results may provide a reliable guidance for proper planning design of the scanning region, which is valuable to help minimize the extra dose to patient. Questionnaires were distributed to Radiology departments at hospitals with 300 sickbeds throughout the Pohang region of North Gyeongsang Province concerning awareness and performance levels of infection control. The investigation included measurements of the pollution levels of imaging equipment and assistive apparatuses in order to prepare a plan for the activation of prevention and management of hospital infections. The survey was designed to question respondents in regards to personal data, infection management prevention education, and infection management guidelines.

Development of Vehicle and/or Obstacle Detection System using Heterogenous Sensors (이종센서를 이용한 차량과 장애물 검지시스템 개발 기초 연구)

  • Jang, Jeong-Ah;Lee, Giroung;Kwak, Dong-Yong
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.11 no.5
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    • pp.125-135
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    • 2012
  • This paper proposes the new object detection system with two laser-scanners and a camera for classifying the objects and predicting the location of objects on road street. This detection system could be applied the new C-ITS service such as ADAS(Advanced Driver Assist System) or (semi-)automatic vehicle guidance services using object's types and precise position. This study describes the some examples in other countries and feasibility of object detection system based on a camera and two laser-scanners. This study has developed the heterogenous sensor's fusion method and shows the results of implementation at road environments. As a results, object detection system at roadside infrastructure is a useful method that aims at reliable classification and positioning of road objects, such as a vehicle, a pedestrian, and obstacles in a street. The algorithm of this paper is performed at ideal condition, so it need to implement at various condition such as light brightness and weather condition. This paper should help better object detection and development of new methods at improved C-ITS environment.

Ultrasonographic Resistive Index of the Cranial Pancreaticoduodenal Artery in Normal Conscious Dogs (정상견에서 전방 췌장십이장 동맥의 초음파학적 혈관 저항지수)

  • Eom, Ki-Dong;Lee, Hae-oon;Seong, Yun-sang;Lee, Jeong-min;Lee, Jong-won;Oh, Tae-ho
    • Journal of Veterinary Clinics
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    • v.20 no.3
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    • pp.274-277
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    • 2003
  • The purpose of this study was to determine the range of resistive index(RI) of the cranial pancreaticoduodenal artery(cPDA) in the normal dog's and to assess the possibility of clinical application of RI for diagnosing a pancreatitis. Five patients with acute pancreatitis and 17 healthy adult beagle dogs were used. Duplex color Doppler ultrasonographic examination was performed by using a real-time scanner with 11-MHz linear-array transducer. The dogs were restrained in dorsal recumbency without the use of chemical agent. The mean RI of the normal pancreas(0.63$\pm$0.04) was significantly(t = 5.79, p = 0.001) different from acute pancreatitis dog(0.75$\pm$0.04). Duplex color Doppler ultrasonography was an useful technique for detecting and measuring RI of the cPDA. The evaluation of RI of the cPDA may be a valuable supportive diagnostic procedure for evaluating the pancreatitis or suspected in dogs.

A study on Broad Quantification Calibration to various isotopes for Quantitative Analysis and its SUVs assessment in SPECT/CT (SPECT/CT 장비에서 정량분석을 위한 핵종 별 Broad Quantification Calibration 시행 및 SUV 평가를 위한 팬텀 실험에 관한 연구)

  • Hyun Soo, Ko;Jae Min, Choi;Soon Ki, Park
    • The Korean Journal of Nuclear Medicine Technology
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    • v.26 no.2
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    • pp.20-31
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    • 2022
  • Purpose Broad Quantification Calibration(B.Q.C) is the procedure for Quantitative Analysis to measure Standard Uptake Value(SUV) in SPECT/CT scanner. B.Q.C was performed with Tc-99m, I-123, I-131, Lu-177 respectively and then we acquired the phantom images whether the SUVs were measured accurately. Because there is no standard for SUV test in SPECT, we used ACR Esser PET phantom alternatively. The purpose of this study was to lay the groundwork for Quantitative Analysis with various isotopes in SPECT/CT scanner. Materials and Methods Siemens SPECT/CT Symbia Intevo 16 and Intevo Bold were used for this study. The procedure of B.Q.C has two steps; first is point source Sensitivity Cal. and second is Volume Sensitivity Cal. to calculate Volume Sensitivity Factor(VSF) using cylinder phantom. To verify SUV, we acquired the images with ACR Esser PET phantom and then we measured SUVmean on background and SUVmax on hot vials(25, 16, 12, 8 mm). SPSS was used to analyze the difference in the SUV between Intevo 16 and Intevo Bold by Mann-Whitney test. Results The results of Sensitivity(CPS/MBq) and VSF were in Detector 1, 2 of four isotopes (Intevo 16 D1 sensitivity/D2 sensitivity/VSF and Intevo Bold) 87.7/88.6/1.08, 91.9/91.2/1.07 on Tc-99m, 79.9/81.9/0.98, 89.4/89.4/0.98 on I-123, 124.8/128.9/0.69, 130.9, 126.8/0.71, on I-131, 8.7/8.9/1.02, 9.1/8.9/1.00 on Lu-177 respectively. The results of SUV test with ACR Esser PET phantom were (Intevo 16 BKG SUVmean/25mm SUVmax/16mm/12mm/8mm and Intevo Bold) 1.03/2.95/2.41/1.96/1.84, 1.03/2.91/2.38/1.87/1.82 on Tc-99m, 0.97/2.91/2.33/1.68/1.45, 1.00/2.80/2.23/1.57/1.32 on I-123, 0.96/1.61/1.13/1.02/0.69, 0.94/1.54/1.08/0.98/ 0.66 on I-131, 1.00/6.34/4.67/2.96/2.28, 1.01/6.21/4.49/2.86/2.21 on Lu-177. And there was no statistically significant difference of SUV between Intevo 16 and Intevo Bold(p>0.05). Conclusion Only Qualitative Analysis was possible with gamma camera in the past. On the other hand, it's possible to acquire not only anatomic localization, 3D tomography but also Quantitative Analysis with SUV measurements in SPECT/CT scanner. We could lay the groundwork for Quantitative Analysis with various isotopes; Tc-99m, I-123, I-131, Lu-177 by carrying out B.Q.C and could verify the SUV measurement with ACR phantom. It needs periodic calibration to maintain for precision of Quantitative evaluation. As a result, we can provide Quantitative Analysis on follow up scan with the SPECT/CT exams and evaluate the therapeutic response in theranosis.

Studies on the Lipid and Fatty Acid Compositions of Ark-Shell, Anadara broughtonii (피조개 지질 및 지방산 조성에 관한 연구)

  • 문숙임
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.4
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    • pp.436-442
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    • 1992
  • The present study was designed to analyze the lipid and fatty acid compositions of ark shell, Anadara broughtonii. The crude lipid was extracted by Bligh and Dyer's method, and then fractionated by TLC and quantitatively analyzed by TLC scanner. Lipid extracted from ark shell was fractionated into neutral and polar lipid by column chromatography with silicic acid. The fatty acid composition of lipid fractions were determined by gas liquid chromatography. Total lipid content of ark shell was 0.83% base on wet weight. The content of unsaponifiable matter was 20.19%, and iodine value was 156.13. The main components of total lipids were triglyceride, diglyceride, hydrocarbon, and sterol ester. The fatty acid composition of total lipid chiefly consisted of $C_{17 : 0}$, $C_{16 : 0}$, $C_{18 : 1}$ and $CT_{16 : 1}$. The main fatty acids of neutral lipid were $C_{16 : 0}$, $C_{18 : 1}$, $C_{22 : 1}$, $C_{18 : 0}$ and $C_{16 : 1}$. The major fatty acids of polar lipid were $C_{16 : 0}$, $C_{18 : 2}$, $C_{20 : 5}$ and $C_{22 : 6}$. In total lipid fractionation, saturated acid contents were high in all (SA>MA> PA), in neutral lipid fractionation, menoenoic acid contents were high in all (MA > SA> PA), and in polar lipid fractionation, saturated acid con-tents were high in all (SA> PA> MA).

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Accuracy of implant digital scans with different intraoral scanbody shapes and library merging according to different oral exposure height (구내 스캔바디의 형태에 따른 임플란트의 디지털 스캔 정확도 및 구강 내 노출 높이에 따른 라이브러리 중첩 정확도 비교 연구)

  • Jeong, Byungjoon;Lee, Younghoo;Hong, Seoung-Jin;Paek, Janghyun;Noh, Kwantae;Pae, Ahran;Kim, Hyeong-Seob;Kwon, Kung-Rock
    • The Journal of Korean Academy of Prosthodontics
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    • v.59 no.1
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    • pp.27-35
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    • 2021
  • Purpose: The purpose of this study is to compare the accuracy of digital scans of implants according to different shapes of scanbodies, and to compare the accuracy of library merging according to different oral exposure height. Materials and methods: A master model with a single tooth edentulous site was prepared. For the first experiment, three types of intraoral scanbodies were prepared, divided into three groups, and the following experiments were conducted for each group: An internal hex implant was placed. The master model with the scanbody connected was scanned with a model scanner, and a master reference file (control group) was created. 10 files (experimental group) were created by performing 10 consecutive scans with an intraoral scanner. After superimposing the control and experimental groups, the following values were calculated: 1) Distance deviation of a designated point on the scanbody 2) Angle deviation of the major axis of the scanbody. For the second experiment, the scanbody scan data were prepared in 6 different heights. Library files were merged with each of the scan data. The distance and angular deviation were calculated using the 7 mm scan data as control group. Results: In the first experiment, there were no significant differences between A and B (P=.278), B and C (P=.568), and C and A (P=.711) in the distance deviations. There were no significant differences between A and B (P=.568), B and C (P=.546), and C and A (P=.112) in the angular deviations. Also, the scanbody showed significantly higher library merging accuracy in the groups with high oral exposure height (P<.5). Conclusion: There were no significant differences in scan accuracy according to the different shapes of scanbodies, and the accuracy of library merging increased according to exposure height of the scanbody in the oral cavity.

Growth Characteristics and Content of Sarsasapogenin in Different Plant Parts of Anemarrhena asphodeloides Bunge (知母의 生育特性과 部位別 Sarsasapogenin 含量)

  • 허일범
    • Korean Journal of Plant Resources
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    • v.10 no.2
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    • pp.183-187
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    • 1997
  • This study was carried out to find the growth characteristics and content of sarsasapogenin in different plant parts of Anemarrhena asphodeloides Bunge. Five native-cultivars were collected and evaluated for several agronomic traits. The collected native-cultivars were classified into two seed-attached peduncle and vegetative propagation types. Seed-attached peduncle lines were predominance of growth traits than vegetative propagation. For the content of sarsasapogenin in each part was investigated, BuOH extarct of 'timo' was developed on silica gel 60G plate using elution solvent($CHC1_2$: Methyl ethyl Ketone : EtOH = 11 : 2 : 0.5). The developed plate were examined using Dual Wavelength Zig - Zag using. Content of sarsasapogenin in main root and lateral root were respectively 1.67mg/g and 1.31mg/g.

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