통합 검색 | Korea Science

장은주;최동국;박태규;황금희
- 생약학회지
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- 제38권1호
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- pp.27-30
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- 2007
We examined the inhibitory activities against monoamine oxidase (MAO) of Chrysanthemum indicum L. in vitro and in vivo methods. Methanolic extract of C. indicum showed significant inhibitory activities on MAO-A that were prepared from rat brain in vitro. The inhibitory activities were measured by serotonin as a substrate. The $IC_{50}$ value of methanolic extract of C. indicum was 0.24 mg/ml for the inhibition of MAO-A. The ethylacetate fraction of methanolic extract of C. indicum exhibited the best activity toward MAO-A with $IC_{50}$ value of 0.05 mg/ml in vitro. It was observed that those activities in vivo tests have different tendency each other. Ethanolic extract of C. indicum was have no effect on rat MAO by the oral administration (p<0.05). However, MAO inhibitory activities of ethanolic extract of C. indicum by the oral administration have similar tendency to those of iproniazid. Consequently, we suggest that C. indicum may have the effects on the inhibitory activities against MAO both in vitro and in vivo. These results indicates that the C. indicum extract has properties indicative of potential neuroprotective ability.
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박동성;장현식;주재준;문경모;조광운;김양수;박주식;권일근;조면철;양승한
- 대한설비공학회:학술대회논문집
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- 대한설비공학회 2008년도 동계학술발표대회 논문집
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- pp.125-130
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- 2008
The main components of the KSTAR helium refrigeration system (HRS) can be classified into the warm compression system (WCS) and the cryogenic devices according to the operating temperature levels. The WCS itself consists of the compressor station (C/S) and the oil removal system (ORS). The process helium is compressed from 1 bar to 22 bar maximum in the C/S and downstream, the ORS removes the oil mixed in the helium to less than 10 ppbw as per the operation criteria of the cryogenic devices of the KSTAR HRS. After the installation, the pre-commissioning and commissioning activities were started on July, 2007. Before the start-up of the C/S, vibration measurement and the skid reinforcement jobs were performed for stable operation of the C/S. The results of the WCS performance tests met the requirements of the KSTAR HRS but satisfied the vibration level criteria only at the compressors' full load condition.
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