• Journal of Chest Surgery
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• 제21권1호
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• pp.26-35
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• 1988

The effect of cardiopulmonary bypass on platelet count, platelet function, and bleeding time was studied in 60 patients. Platelet count was significantly reduced during and after cardiopulmonary bypass. Platelet function also had a reduced aggregation response to adenosine diphosphate. Bleeding time was prolonged to over 30 minutes during cardiopulmonary bypass and not returned to normal level until postbypass 1 hour. The amount of postoperative bleeding was proportional to the degree of decrease in platelet count and function, degree of decrease in platelet count and function. There was no significant correlation between duration of cardiopulmonary bypass and platelet count, platelet function, bleeding time, or amount of postoperative bleeding. Patients with cyanotic congenital heart disease showed a larger amount of postoperative bleeding than patients with acyanotic congenital heart disease [P<0.01], and this difference was due to the fact that platelet function was more significantly affected by cardiopulmonary bypass in cyanotic group. Patients using membrane oxygenator showed a less amount of postoperative bleeding than patients using bubble oxygenator [p<0.005] reflecting better preservation of platelet count and function by membrane oxygenator.

• Journal of Chest Surgery
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• 제18권2호
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• pp.193-204
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• 1985

During the period from February to March, 1984, we employed a partial left heart bypass [left atrium to ascending aorta] in 2 patients who could not weaned from cardiopulmonary bypass with inotropic agents and cardiac pacing after coronary bypass surgery. These two patients showed significant improvement in ventricular function 18 to 47 hours after inserting the left heart bypass and were able to wean from the left heart bypass under using inotropic agents. Two patients died of multiple organ failures 11 days and 15 days postoperatively. These results indicate that early institution of left heart bypass in ventricular failure patients after open heart surgery can provide satisfactory long-term result.

• Journal of Chest Surgery
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• 제7권1호
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• pp.73-78
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• 1974

Influences on organ function were studied in animals during prolonged extracorporeal circulation with a bubble type of oxygenator. More than six hours of total cardiopulmonary bypass was performed under mild hypothermia by means of an extracorporeal circulation system in five dogs. Obtained results were summarized as follows. 1. The renal function was not so impaired seriously until four hours of extracorporeal circulation. However, there was more serious impairment of renal function in this study when extracorporeal circulation was carried out for a period of five hours or more. 2. There was gradual hepatic damage during extracorporeal circulation and the damage was more significant after bypass for a period of five to six hours. 3. There was a significant decrease in serum K during bypass, irrespective of the pump oxygenator prime with a high K solution. The reason for this is complex and due to many factors, however, it was evidently related to serum glucose levels during extracorporal circulation.

• Journal of Chest Surgery
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• 제23권6호
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• pp.1152-1157
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• 1990

Colloid solution is commonly used to increase the oncotic pressures of priming solutions used in the cardiopulmonary bypass circuit. To study the effectiveness of this practice, we retrospectively evaluated 24 patients undergoing cardiac operations to receive isoelectric solution plus 50 gm of albumin[group A], isoelectric solution plus 25 gm of albumin[group B] and isoelectric solution without albumin[group C] as the prime solution for the bypass circuit. Various clinical parameters related to the perioperative fluid balance, cardiopulmonary function, and renal function were studied. There were no differences between the three groups with regard to postoperative clinical parameter of cardiopulmonary, liver function and renal function. But at the previous report by Cho et al. [38], there was a significant difference between groups with regard to hematologic property, especially in crenated red blood cells. These hematologic events did not affect the clinical outcome but thorough evaluations are needed in order to prove the clinical effect of crenated red blood cell. We conclude that there is no clinically detectable advantage for the routinely supplementing of albumin to the priming solution of bypass circuit in cardiac operations. Whether this practice can be of value in selected cases needs to be further studied.

• International Journal of Air-Conditioning and Refrigeration
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• 제9권1호
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• pp.11-19
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• 2001

To establish optimum cycle of the inverter-driven heat pump with a variation of frequency, the bypass orifice, which was a short tube haying a bypass hole in the middle, was designed and tested. Flow characteristics of the bypass orifice were measured as a function of orifice geometry and operating conditions. Flow trends with respect to frequency were compared with those of short tube orifices and capillary tubes. Generally, the bypass orifice showed the best flow trends among them. and it would enhance the seasonal energy efficiency ratio of an inverter heat pump system, Based on experimental data, a semi-empirical flow model was developed to predict mass flow rate through bypass orifices. The maximum difference between measured data and model`s prediction was within $\pm$5%.

• 설비공학논문집
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• 제11권1호
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• pp.109-116
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• 1999

To establish optimum cycle of the inverter-driven heat pump with a variation of frequency, the bypass orifice, which is a short tube having a bypass hole in the middle, was designed and tested. Flow characteristics of the bypass orifice were measured as a function of orifice geometry and operating conditions. Flow trends with respect to frequency were compared with those of short tube orifices and capillary tubes. Generally, the bypass orifice showed the best flow trends among them, that will enhance the seasonal energy efficiency ratio of an inverter heat pump system. Based on experimental data, the semi-empirical flow model was developed to predict mass flow rate through bypass orifices. The maximum difference between measured data and model's prediction was within ${\pm}5%$.

• Journal of Microbiology and Biotechnology
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• 제6권5호
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• pp.315-320
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• 1996

The role of glyoxylate bypass in a lysine-producing Corynebacterium lactofermentum strain was analyzed. Unlike the wild type, the strain expressed enzymes of glyoxylate bypass during growth in the fermentation broth containing glucose as the carbon source. To evaluate the importance of glyoxylate bypass in the strain, we disrupted chromosomal aceA by using a cloned fragment of the gene. Site-specific disruption of aceA which codes for the isocitrate lyase, the first enzyme of the bypass, was confirmed by Southern blot analysis. The aceA mutant strain completely lost isocitrate lyase activity and ability to grow in a minimal medium containing acetate as the sole carbon source. The mutant strain was similar to its parental strain in growth characteristics and produced comparable amounts of lysine in shake flasks containing glucose as the carbon source. The amount of oxaloacetate accumulated in the fermentation medium was similar for both strains, suggesting that expression of glyoxylate bypass does not necessarily lead to the increase in intracellular oxaloacetate. These data clearly demonstrate that glyoxylate bypass does not function as one of the routes of carbon supply for lysine production in the strain. It appears that the leakiness of the glyoxylate bypass in the strain might be the result of a secondary mutation which arose during previous strain development by random mutagenesis.

• 전기학회논문지
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• 제59권12호
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• pp.2212-2217
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• 2010

Previous studies have been focused on the voltage of Bypass diode and Isc(Short Circuit Current) of the influenced solar cell. The Bypass diode starts working when it gets the reverse applied voltage. Previous studies have only concentrated on Isc of the influenced solar cell and Imp of PV module to explain the bypassing performance. PV module is usually working together with inverter having MPPT(Maximum Power Point Tracking) function for best performance. bypassing point is regulated by MPPT function of inverter. In this paper, simulation results of Bypass diode in PV module have been analyzed to represent the relationship of the bypassing point with the composition of PV module. From the results, the more cells are connected with each string, the earlier bypassing performance happens under the fixed number of strings. As diode groups increase or irradiation decreases, the bypassing performance starts fast.

• Journal of Chest Surgery
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• 제27권7호
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• pp.571-575
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• 1994

The hemodynamic effects of thyroid hormone are well established, and this hormone affects myocardial contractility, heart rate, and myocardial oxygen consumption. But the role of cardiopulmonary bypass on the thyroid function is not yet fully understood. We have studied twelve patients [male and female patients were equal in number] who were performed open heart surgery under cardiopulmonary bypass. The results are followed. 1] The serum level of T3 began to fall after cardiopulmonary bypass and sustained significantly till 24 hours after operation[p<0.05] 2] The concentrations of T4, Free T4, and TSH were slightly decreased after cardiopulmonary bypass but was maintained within normal range. 3] This above findings are similar to the "sick sinus syndrome" that is seen in severely ill patient. 4] We can propose that T3 would be effective in postoperative low cardiac output syndrome. syndrome.

• 정보보호학회논문지
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• 제30권5호
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• pp.881-893
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• 2020

CFI(Control Flow Integrity)는 제어 흐름을 검증해 프로그램을 보호하는 기법이다. 안드로이드 환경에서 애플리케이션 보호를 위해 LLVM Clang 컴파일러가 지원하는 CFI 기법인 IFCC(Indirect Function Call Checks)와 SCS(Shadow Call Stack)이 도입되었다. IFCC가 함수 호출, SCS이 함수 복귀 시 제어 흐름을 보호한다. 본 논문에서는 IFCC, SCS을 적용한 애플리케이션 환경에서 CFI 우회 공격기법을 제안한다. 사용자 애플리케이션에 IFCC, SCS을 적용하여도 애플리케이션 메모리 내 IFCC, SCS으로 보호되지 않은 코드 영역이 다수 존재하는 것을 확인하였다. 해당 코드 영역에서 공격을 위한 코드를 실행해 1) IFCC로 보호된 함수 우회 호출 기법, 2) SCS 우회를 통한 복귀 주소 변조 기법을 구성한다. 안드로이드10 QP1A. 191005.007.A3 환경에서 IFCC, SCS으로 보호되지 않은 코드 영역을 식별하고 개념 증명(proof-of-concept) 공격을 구현해 IFCC, SCS이 적용된 환경에서 제어 흐름 변조가 가능함을 보인다.