• Title/Summary/Keyword: Burden of Failure

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Trends in Regional Disparity in Cardiovascular Mortality in Korea, 1983-2019

  • Eunji Kim;Jongmin Baek;Min Kim;Hokyou Lee;Jang-Whan Bae;Hyeon Chang Kim
    • Korean Circulation Journal
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    • v.52 no.11
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    • pp.829-843
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    • 2022
  • Background and Objectives: Despite remarkable reduction in cardiovascular disease (CVD) mortality, the burden has remained the leading cause of death. Since little research has focused on regional disparity in CVD mortality, this study aims to investigate its spatiotemporal trends in Korea from 1983 to 2019. Methods: Using the causes of death statistics in Korea, we analyzed the geographic variation in deaths from CVDs from 1983 to 2019. The sex and age-standardized mortality rate was calculated according to the 17 administrative regions. The analyses include all diseases of the circulatory system (International Classification of Diseases-10 codes, I00-I99), along with the following 6 subcategories which were not mutually exclusive: total heart disease (I00-I13 and I20-I51), hypertensive heart disease (I10-I13), ischemic heart disease (I20-I25), myocardial infarction (I21-I23), heart failure (I50), and cerebrovascular disease (I60-I69). Results: Overall, heart failure death rate increased across all regions, and other CVD death rates showed a decreasing trend. Regional disparity in mortality was substantial in the early 1980s but converged over time. In all types of cardiovascular mortality, Busan, Ulsan and Gyeongnam remained the highest, although they showed a downward trend like other regions. Jeju continued to have a relatively low CVD mortality rate. Conclusions: The regional disparity substantially decreased compared to the 1980s. However, the relatively high burden of CVD mortality in the southeastern region has not been fully resolved.

IoT Collaboration System Based on Edge Computing for Smart Livestock System (스마트 축사를 위한 에지 컴퓨팅 기반 IoT 협업 시스템)

  • Ahn, Chi-Hyun;Lee, Hyungtak;Chung, Kwangsue
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.2
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    • pp.258-264
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    • 2022
  • The smart farm for livestock, in which information and communication technology (ICT) is combined with livestock farm, is mostly based on the cloud computing paradigm. A cloud-based smart livestock farm has disadvantages such as increased response time, burden on cloud resource caused by the increased number of IoT sensors, traffic burden on the network, and lack of failure resilience mechanisms through collaboration with adjacent IoT devices. In this paper, with these problems in mind, we propose an IoT collaboration system based on edge computing. By using the relatively limited computing resources of the edge device to share the cloud's web server function, we aim to reduce the cloud's resources needed and improve response time to user requests. In addition, through the heartbeat-based failure recovery mechanism, IoT device failures were detected and appropriate measures were taken.

Sepsis: Early Recognition and Optimized Treatment

  • Kim, Hwan Il;Park, Sunghoon
    • Tuberculosis and Respiratory Diseases
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    • v.82 no.1
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    • pp.6-14
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    • 2019
  • Sepsis is a life-threatening condition caused by infection and represents a substantial global health burden. Recent epidemiological studies showed that sepsis mortality rates have decreased, but that the incidence has continued to increase. Although a mortality benefit from early-goal directed therapy (EGDT) in patients with severe sepsis or septic shock was reported in 2001, three subsequent multicenter randomized studies showed no benefits of EGDT versus usual care. Nonetheless, the early administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis. In 2016, new sepsis definitions (Sepsis-3) were issued, in which organ failure was emphasized and use of the terms "systemic inflammatory response syndrome" and "severe sepsis" was discouraged. However, early detection of sepsis with timely, appropriate interventions increases the likelihood of survival for patients with sepsis. Also, performance improvement programs have been associated with a significant increase in compliance with the sepsis bundles and a reduction in mortality. To improve sepsis management and reduce its burden, in 2017, the World Health Assembly and World Health Organization adopted a resolution that urged governments and healthcare workers to implement appropriate measures to address sepsis. Sepsis should be considered a medical emergency, and increasing the level of awareness of sepsis is essential.

An Instrument Fault Detection Scheme using Function Observers (함수관측자를 이용한 장치고장검출 기법)

  • Lee, Sang-Moon;Lee, Kee-Sang
    • The Transactions of the Korean Institute of Electrical Engineers D
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    • v.55 no.3
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    • pp.91-97
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    • 2006
  • A major difficulty with the practical application of the multiple observer based IFDI schemes is the computational burden of the residual generation. In this paper, a new residual generator that employs function observers is proposed to reduce the computational burden, and the design methods of the IFDIS, equipped with the residual generator, are presented. The function observers employed in the residual generator can be considered as a dual of the unknown input (function) observer And it can be designed to estimate the measurement errors that are due to sensor faults. The error estimates are further processed to generate the residuals by which reliable fault detection/isolation result car be obtained. The proposed scheme is more useful, in real-time application, than any other multiple state observer based IFDISs. It can be effectively applied to fault tolerant control because the failure effects can be compensated by the use of the estimates of measurement errors. The proposed IFDI scheme is applied to an inverted pendulum control system for the IFDI of failed sensor and fault compensation.

A study on the Design and Realization of the Wrist Type Module System based on the Smart Device Receiving Information Relay (스마트 디바이스 착신정보 중계 기반 손목형 모듈 시스템 설계 및 구현)

  • Jeong, Hee Ja
    • Smart Media Journal
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    • v.5 no.4
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    • pp.131-137
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    • 2016
  • Since the phenomenon that the consumers slip important calls since they do not know the receiving information of the smart phone in spaces which smart phones can not be carried, the development of technology to solve this problem is urgent and the cases of burglary and losses of smart phones during hobby and recreation life are increasing and especially since burglary behaviors are occurring much in places such as bathing resort, swimming pool, Korean dry sauna, sauna and spa etc, the schemes to protect smart phones during hobbies and recreation life is needed. Since the smart watch, the conventional wearable device are high price machines and due to the burden about A/S costs for the damage or failure of the machine during exercise, hobbies and recreation activities, the burden about the use is high, development of products which can reduce such burden and emphasize the usefulness is urgent and in order to solve this problem, the added value and psychological repercussion effect will be very high in areas of smart phone users and utilizing them by developing the system which can know if the smart phone has received calls at least in places where smart phones can not be carried.

The Experience of Life Reconstruction in Hemodialysis Patients with Chronic Renal Failure (만성신부전 혈액투석 환자의 삶의 재구성 경험에 관한 현상학적 연구)

  • Kim, Yun-Jeong;Kwon, Su-hye
    • Journal of Digital Convergence
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    • v.15 no.9
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    • pp.321-333
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    • 2017
  • This study was a qualitative study using Colaizzi's phenomenological study method to understand the experience of reconstructing life through hemodialysis in chronic renal failure patients and to clarify the meaning of their vivid experience. The participants were eight chronic renal failure patients receiving hemodialysis. Data were collected through individual in - depth interviews with participants. The five categories that were found in the study were 'The beginning of unexpected difficulties', 'Burden of survival brought on by hemodialysis', 'The driving force of recovery', 'Choices and concentration of today in order', ' Every day life which must be woven sincerely'. The results of this study will help clinicians better understand the physical and mental suffering experienced by patients with chronic renal failure receiving hemodialysis and how they are constantly trying to adapt to a changed lifestyle. Also it might provide basic data for the development of efficient nursing intervention for the health management of hemodialysis patients.

Interpretation of cardiovascular outcome trials results of new antidiabetic agents (당뇨병 신약의 cardiovascular outcome trials 결과의 해석)

  • Gwanpyo Koh;Hyounjung Chin
    • Journal of Medicine and Life Science
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    • v.21 no.3
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    • pp.62-71
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    • 2024
  • The incidence of diabetes is continuously increasing worldwide, resulting in a considerable socioeconomic burden. Glycemic control using traditional diabetes medications prevents microvascular complications; however, there is no objective evidence that it prevents macrovascular complications. In the 21st century, concerns have arisen that strict glycemic control and the diabetes drug rosiglitazone might increase mortality. This led the United States Food and Drug Administration to establish guidelines that require that cardiovascular outcome trials (CVOTs) with 3-point major adverse cardiovascular events (3-P MACE) as the primary endpoints be performed for new diabetes drugs. Since then, 20 CVOTs have been reported. Dipeptidyl peptidase 4 inhibitors do not increase the incidence of cardiovascular disease; however, saxagliptin increases the risk of heart failure. Sodium-glucose cotransporter inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP-1RAs) not only have proven cardiovascular safety but also have shown results beyond expectations by reducing the incidence of cardiovascular diseases. Additionally, SGLT2is have been reported to markedly prevent heart failure and kidney disease. The reduction in 3-P MACE by GLP-1RAs was observed only with long-acting agents; long-acting GLP-1RAs also markedly reduced renal endpoints. However, no preventive effect against heart failure was observed with GLP-1RAs. The preventive effects of both drug types against cardiovascular and kidney diseases appear to be independent of glycemic control. In conclusion, based on CVOT results, it is necessary to actively prescribe SGLT2is and GLP-1RAs to prevent cardiovascular disease in patients with diabetes, regardless of glycemic control.

ID-Based Group Key Management Protocols for Dynamic Peer Groups (피어 그룹을 위한 ID 기반의 그룹키 관리 프로토콜)

  • Park, Young-Ho;Lee, Kyung-Hyune
    • Journal of Korea Multimedia Society
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    • v.7 no.7
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    • pp.922-933
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    • 2004
  • In recent years, peer-to-peer network have a greate deal of attention for distributed computing or collaborative application, and work of ID-based public key systems have been focusing on the area of cryptography. In this paper, we propose ID-based group key management protocols for secure communication in autonomous peer group. Each member obtains his public/private key pair derived from his identification string from Private Key Generator. No central server participates in group key management protocol instead, all group members share the burden of group key management by the collaboration of themselves, so that our scheme avoids the single point of failure problem. In addition, our scheme considers the nature of dynamic peer group such as frequent joining and leaving of a member.

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A Study on the Ultrasonic Nano Crystal Surface Modification(UNSM) Technology and It's Application (초음파 나노표면개질기술의 특성과 활용방안 연구)

  • Pyoun, Young-Sik;Park, Jeong-Hyeon;Cho, In-Ho;Kim, Chang-Sik;Suh, Chang-Min
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.33 no.3
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    • pp.190-195
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    • 2009
  • All the failure in fatigue of torsion, bending and rolling contact, and in sliding wear begins mostly from surface. So much efforts have been invested to the surface technology which deal these problems during past decades, but the industrial demand keeps growing and more significant requirements are added to researchers and engineers. Nano crystal surface modification technology which makes the surface layers into nano crystalline, induces big and deep compressive residual stress, increases surface hardness, improves surface hardness, and make micro dimples structure on surface is an emerging technology which can break limits of current surface technology and relieve the burden of researchers and engineers. In this study, a nano crystal surface modification technology which is calling UNSM(Ultrasonic nano crystal surface modification) technology, is introduced and how it has been applied to industry to solve these failure problems is explained.

Implications of Managing Chronic Obstructive Pulmonary Disease in Cardiovascular Diseases

  • Deshmukh, Kartik;Khanna, Arjun
    • Tuberculosis and Respiratory Diseases
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    • v.84 no.1
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    • pp.35-45
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    • 2021
  • Globally, cardiovascular diseases and chronic obstructive pulmonary disease (COPD) are the leading causes of the non-communicable disease burden. Overlapping symptoms such as breathing difficulty and fatigue, with a lack of awareness about COPD among physicians, are key reasons for under-diagnosis and resulting sub-optimal care relative to COPD. Much has been published in the past on the pathogenesis and implications of cardiovascular comorbidities in COPD. However, a comprehensive review of the prevalence and impact of COPD management in commonly encountered cardiac diseases is lacking. The purpose of this study was to summarize the current knowledge regarding the prevalence of COPD in heart failure, ischemic heart disease, and atrial fibrillation. We also discuss the real-life clinical presentation and practical implications of managing COPD in cardiac diseases. We searched PubMed, Scopus, EMBASE, and Google Scholar for studies published 1981-May 2020 reporting the prevalence of COPD in the three specified cardiac diseases. COPD has high prevalence in heart failure, atrial fibrillation, and ischemic heart disease. Despite this, COPD remains under-diagnosed and under-managed in the majority of patients with cardiac diseases. The clinical implications of the diagnosis of COPD in cardiac disease includes the recognition of hyperinflation (a treatable trait), implementation of acute exacerbations of COPD (AECOPD) prevention strategies, and reducing the risk of overuse of diuretics. The pharmacological agents for the management of COPD have shown a beneficial effect on cardiac functions and mortality. The appropriate management of COPD improves the cardiovascular outcomes by reducing hyperinflation and preventing AECOPD, thus reducing the risk of mortality, improving exercise tolerance, and quality of life.