• The Korean Journal of Physiology and Pharmacology
• /
• v.3 no.4
• /
• pp.383-391
• /
• 1999

This study was carried out to determine whether the effects of an ${\alpha}_2-adrenoceptor$ agonist, clonidine, on mean arterial pressure (MAP) and heart rate (HR) are influenced by mild hypothermia. Experiments were performed in respiration-controlled and spontaneously breathing pentobarbital-anesthetized rats. Rectal temperature was maintained at $37.5{\pm}0.3^{circ}C$ for normothermic groups or at $35.2{\pm}0.3^{circ}C$ for mild hypothermic groups. Intravenous injection of clonidine (1 and 2 ${\mu}g/kg)$ produced depressor and bradycardic responses in spontaneously breathing rats under both normothermic and mild hypothermic condition: a decrease in MAP was not altered but bradycardic response was significantly augmented in the mild hypothermic group as compared with the normothermic group. Under the respiration-controlled condition, the hypotensive effect of clonidine $(2\;{\mu}g/kg)$ was reduced, whereas the bradycardic effect was increased in mild hypothermic rats as compared with normothermic rats. Both hypotensive and bradycardic effects of clondine $(2\;{\mu}g/kg)$ were blocked by pretreatment with an ${\alpha}_2-adrenoceptor$ antagonist, yohimbine (0.5 mg/kg), in both thermal conditions. Yohimbine (0.5 mg/kg, i.v.) alone produced signifcantly an increase in heart rate in the mild hypothermic group than in the normothermic group. Pretreatment with a muscarinic receptor antagonist, atropine methylnitrate (1 mg/kg, i.v.), attenuated the bradycardic effect of clonidine in the mild hypothermic group but not in the normothermic group. These results suggest that clonidine- induced bradycardia is amplified by mild hypothermia probably through an increased parasympathetic activity.

• Science of Emotion and Sensibility
• /
• v.22 no.1
• /
• pp.89-100
• /
• 2019

Sleep apnea, a medical condition associated with a variety of complications, is generally monitored by standard sleep polysomnography, which is expensive and uncomfortable. To overcome these limitations, this study proposes an unconstrained wearable monitoring system with stretch-fiber sensors that integrate with the wearer's clothing. The system allows patients to undergo examinations in a familiar environment while minimizing the occurrence of skin allergies caused by adhesive tools. As smart clothing for adult males with sleep apnea, long-sleeved T-shirts embedding fibrous sensors were developed, enabling real-time monitoring of the patients' breathing rate, oxygen saturation, and airflow as sleep apnea diagnostic indicators. The gauge factor was measured as 20.3 in sample 4. The maximum breathing intake, measured during three large breaths, was 2048 ml. the oxygen saturation was measured before and during breath-holding. The oxygen saturation change was 69.45%, showing a minimum measurable oxygen saturation of 70%. After washing the garment, the gauge factor reduced only to 18.0, confirming the durability of the proposed system. The wearable sleep apnea monitoring smart clothes are readily available in the home and can measure three indicators of sleep apnea: respiration rate, breathing flow and oxygen saturation.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2017.06a
• /
• pp.193-193
• /
• 2017

The black heart in potato is a physiological disorder that occurs when potatoes suffer from breathing problems. When storing potatoes at a low temperature around $0^{\circ}C$, there is a high possibility that the respiration rate of potato will rise and black heart will occur. Also, respiration can occur easily and briefly in a state where high temperature and ventilation is insufficient. Recently, as black heart has been occurred continuously and severely in South Korea, here we tried to identify the causes of black heart in potato and to develop the control strategy of this disorder. Firstly, we analyzed the influence on the black heart on the basis of preservation containers (breathable plastic box, burlap bag, paper box, sealed plastic box). After harvesting the potato which is cv. Superior, it preserved for 6 months under conditions of temperature $3.5^{\circ}C{\pm}0.2$ and humidity 85%, after then we surveyed the incidence of emergence rate, rate of weight loss and occurrence rate of black heart. Secondly, in order to investigate the time point of black heart initiation under the oxygen concentration condition of 1% or less, The potatoes were used for this experiment stored for 6 months in a aerated plastic box under conditions of temperature $3.5^{\circ}C{\pm}0.2$ and humidity 85% under sufficient oxygen condition. After stored for 6 month, those were stored at $15^{\circ}C$ and below 1% of oxygen for 25 days, and then the incidence of black heart was surveyed. Thirdly, to investigate the effects of the number of days after harvest on the occurrence of black heart, it was examined the occurrence of black heart stored on 40 days and 100 days after harvesting under sealed condition and vacuum condition. The temperature condition of potato storage was stored was at $4^{\circ}C$ and $25^{\circ}C$ in humidity 85%. As a result of investigating the occurrence of black heart depending on the storage containers, all of the potatoes stored in the sealed plastic box had been occurred black heart. However, black heart of the potatoes in the other treatments did not. Potato preserved under the condition of below 1% of oxygen was found to occur 32% black heart after 25 days of storage. The potatoes corresponding to the required number of days after harvesting were stored for 31 days and the black heart was examined on the occurred. As a result, the potatoes which were 40 days after the harvest did not have black heart under sealed condition and vacuum condition. But potatoes harvested 100 days after harvesting had a black heart incidence of 95.7% under sealed condition at $4^{\circ}C$. The potato placed in the vacuum condition and a sealed state at $25^{\circ}C$ was transformed into anaerobic respiration, the inner tissue of tuber collapsed. Therefore, it is considered that black heart is caused by the breathing trouble in the central part when the oxygen is almost consumed after the aerobic respiration which gradually consumes the oxygen. We conclude that the black heart occurred in the central part where exchange of oxygen and carbon dioxide is the slowest is sensitive to respiration disorder. It is thought that research to investigate black heart generation time according to storage conditions and post-harvest state of potatoes is further necessary.

• Progress in Medical Physics
• /
• v.28 no.4
• /
• pp.164-170
• /
• 2017

One of the methods to consider the effect of respiratory motion of a tumor target in radiotherapy is to establish a treatment plan with the internal target volume (ITV) created based on an accurate analysis of the target motion displacement. When this method is applied to intensity modulated radiotherapy (IMRT), it is expected to yield a different treatment dose distribution under the motion condition according to the IMRT method. In this study, we prepared ITV-based IMRT plans with conventional IMRT using fixed gantry angle beams, RapidArc using volumetric modulated arc therapy, and tomotherapy using helical therapy. Then, the variation in dose distribution caused by the target motion was analyzed by the dose measurement in the actual motion condition. A delivery quality assurance plan was prepared for the established IMRT plan and the dose distribution in the actual motion condition was measured and analyzed using a two-dimensional diode detector placed on a moving phantom capable of simulating breathing movements. The dose measurement was performed considering only a uniform target shape and motion in the superior-inferior (SI) direction. In this condition, it was confirmed that the error of the dose distribution due to the target motion is minimum in tomotherapy. This is thought to be due to the characteristic of tomotherapy that treats the target sequentially by dividing it into several slices. When the target shape is uniform and the main target motion direction is SI, it is considered that tomotherapy for the ITV-based IMRT method has a characteristic which can reduce the dose difference compared with the plan dose under the target motion condition.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.50 no.5
• /
• pp.297-308
• /
• 2022

Most air-breathing aircraft operated in the hypersonic region are equipped with a scramjet engine. In a scramjet engine, a shock wave generated at an inlet acts as a compressor for a general gas turbine engine instead, so total pressure loss caused by the shock wave is considered very important. In this study, to minimize total pressure loss, a method of designing an external compression inlet using isentropic compression surface was proposed, and an external compression inlet with 3-deflection angles and Busemann inlet were designed under the same conditions. After that, through computational analysis, the performance characteristics at off-design conditions were compared. Each inlet shape was truncated according to the length of the 3-ramp external compression inlet, and the boundary layer correction was performed. The isentropic external compression inlet showed superior performance at the design point, but under the off-design conditions, its performance was degraded compared to the 3-ramp external compression inlet.

• Journal of the Korea Society of Computer and Information
• /
• v.27 no.11
• /
• pp.191-198
• /
• 2022

The most basic thing to measure the condition of a companion animal is to check the breathing and pulse. There are several methods to measure the breathing and pulse of a companion animal, and the PPG method is generally used to measure the oxygen saturation (SpO₂) in a companion animal. However, since the input PPG signal is inputted with various information as well as oxygen saturation, it is necessary to separate and extract oxygen saturation information from the PPG signal in order to measure the oxygen saturation. Therefore, in this paper, a wearable measuring device for companion animals that can be measured by applying the PPG method was designed and implemented, and an algorithm for separating oxygen saturation information from the PPG signal input through the wearable measuring device was proposed.

• Journal of the Korean Society of Physical Medicine
• /
• v.17 no.2
• /
• pp.95-100
• /
• 2022

PURPOSE: The purpose of this study was to compare the effect of depending on the location of applying chest expansion resistance exercise on the respiratory muscle strength stroke patients, and to suggest more effective interventions to improve respiratory function in stroke patients in clinical practice. METHODS: A total of 30 subjects were selected and divided into two groups, and chest cage extension resistance exercise was applied to the sternum and rib cage, respectively, and performed for 4 weeks, 3 times a week, for 20 minutes. In order to compare the general characteristics of the study subjects and the homogeneity of the group, the pre-experimental values were analyzed using the independent sample t-test. Paired-sample t-test was used for pre-post value comparison of maximum inspiratory pressure and maximum expiratory pressure in each group. Statistical significance was set to .05. RESULTS: Both the sternum application group and the rib cage application group showed a significant difference in the maximum inspiratory pressure according to the intervention. Also, there was a statistically significant difference in the maximum expiratory pressure in the sternum application group. CONCLUSION: As breathing exercise is important for stroke patients, based on the results of this study, if therapists perform sternal extension resistance exercise or rib extension resistance exercise according to the patient's condition and environment, it can help the breathing function of stroke patients.

• Phonetics and Speech Sciences
• /
• v.4 no.2
• /
• pp.115-120
• /
• 2012

This study sought to compare breath competence in three different utterance conditions when reading a passage aloud, making a spontaneous speech, and singing. We tested 15 normal females (ages averaging $24{\pm}4.4$) and measured breath competence through an objective, aero-mechanical instrument called PAS (Phonatory aerodynamic system, model 6600, KAY Electronics, Inc). Breathing sets of inspiration and expiration were measured by breath group number, breath group duration, and the ratio of inspiration to expiration. The results from this study led us to the following conclusion: The breath group number and the breath group duration showed no significant difference. However, the only variance that we could find was in the ratio of inspiration and expiration. In significantly different speech patterns, singing resulted in the most varied ratio of inspiration and expiration, followed by reading a text aloud, and spontaneous speech. The average frequency rates and maximum intensity levels varied with regards to varying utterance conditions. This thus shows that breath competence and phonation competence have a closely interrelated relationship.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.23 no.11
• /
• pp.711-717
• /
• 2011

In this study, 5 types of PVS(Passive ventilation system) units are made and experimented its ventilation performance, thermal performance according to open rate and hole diameter of perforated aluminum plane. Results are as follows. 1) The ventilation performance increases approximately 50~70% according by the open rate of PVS increasing. Also, the ventilation performance increases about 2%~12% according by the hole diameter of PVS increasing. 2) In winter temperature/pressure condition(in : $20^{\circ}C$, out : $-2^{\circ}C/{\Delta}P$ : 0.2~5.0Pa) the temperature of inflow air decreases according by the open rate of PVS increasing. Heat gain performance decreases 10.1%, 25.6% when open rate increases 3) In the same condition, Heat gain performance decreases 18.3%, 18.8% according by the hole diameter of PVS increasing.

• 한국연소학회:학술대회논문집
• /
• 2014.11a
• /
• pp.311-313
• /
• 2014

High pressure combustion with multiphase--liquid, gas, and supercritical phase--mixtures are widely used technology in the high efficiency liquid propellent rocket engine. This is the typical characteristics differentiate from the combustor of conventional air-breathing engines. Therefore, successful research of high pressure combustion at supercritical condition is essential to develope a high efficiency liquid rocket engine. Numerical studies have been carried out to explore capabilities of numerical method for LOx-CH4 non-premixed flames at high pressure. In this paper, corresponding numerical results are presented and compared with experimental result of MASCOTTE facility.