• Title/Summary/Keyword: Breast diameter analysis

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The Significance of Nuclear Size in Nuclear Grade of Invasive Ductal Carcinoma of the Breast (유방의 침윤성 관암종에서 핵등급 기준으로서 핵크기의 의의)

  • Bae, Young-Kyung;Kim, Dong-Sug;Choi, Hye-Juug;Gu, Mi-Jin;Lee, Soo-Jung;Lee, Jea-Young
    • The Korean Journal of Cytopathology
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    • v.10 no.1
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    • pp.21-26
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    • 1999
  • To make the objective standard of nuclear size ingrading nuclear pleomorphism of invasive ductal carcinoma of the breast, we measured maximal nuclear diameter of tumor cells on imprint cytology slides and histologic sections from 65 cases by using computer-based image analysis system(Optimas 6.0). The maximal diameter of red blood cells were also measured to evaluate the ratio of maximal nuclear diameter of tumor cells to maximal diameter of red blood cells. The mean values of maximal nuclear diameter of tumor cells on imprint cytology slides and histologic sections were $7.56{\mu}m,\;7.53{\mu}m$ in nuclear grade 1, $8.92{\pm}0.98{\mu}m,\;9.02{\pm}0.74{\mu}m$ in nuclear grade 2, and $12.90{\pm}1.47{\mu}m,\;12.44{\pm}1.41{\mu}m$ in nuclear grade 3, respectively. There were no significant differences between values of imprint cytology and histologic section. The ratio of maximal nuclear diameter of tumor cells to maximal diameter of red blood cells were 1.3-1.4:1 in nuclear grade 1, 1.6-1.7:1 in nuclear grade 2, and 2.2-2.3:1 in nuclear grade 3. These values would be guidelines for grading nuclear pleomorphism of invasive ductal carcinoma of the breast on routine surgical pathology work.

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Comparison of Brassiere Pattern according to breast shape on China Adult Females (중국 성인여성의 유방유형에 따른 브래지어 패턴 비교)

  • Cha, Su-Joung;Sohn, Hee-Soon
    • Journal of Fashion Business
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    • v.15 no.1
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    • pp.63-79
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    • 2011
  • This study examines the relationship between breast shape and brassiere construction through the comparative analysis of brassiere pattern on the breast shape. This researcher drew the brassiere pattern of developing a pre-study for Chinese female adults according to average size based on the four breast shapes. And then we measures brassiere pattern size and comparatively analyzes breast between size and shape. Comparative analysis results of brassiere patterns are verified differences of size and shape on the breast shape. Above all an angle of cup dart showed remarkable differences on the breast shape. An angle of cup dart isn't proportioned to breast size. An angle of cup dart for cone shape is bigger than dome shape. Because cone shape breast is protruded center part but dome shape breast have a shape of smooth curve like a half globe. So an angle of a cone shape breast cup dart is determined bigger than dome shape breast. For increasing the uplift effect of brassiere, brassiere pattern is different on the breast shape. And a brassiere pattern need different drawing methods about the angle of cup dart, breast inner side diameter, slope and so on. This study has an important significance that it established a mechanical relationship of breast shape and brassiere pattern.

Comparative Study of Contrast-Enhanced Ultrasound Qualitative and Quantitative Analysis for Identifying Benign and Malignant Breast Tumor Lumps

  • Liu, Jian;Gao, Yun-Hua;Li, Ding-Dong;Gao, Yan-Chun;Hou, Ling-Mi;Xie, Ting
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8149-8153
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    • 2014
  • Background: To compare the value of contrast-enhanced ultrasound (CEUS) qualitative and quantitative analysis in the identification of breast tumor lumps. Materials and Methods: Qualitative and quantitative indicators of CEUS for 73 cases of breast tumor lumps were retrospectively analyzed by univariate and multivariate approaches. Logistic regression was applied and ROC curves were drawn for evaluation and comparison. Results: The CEUS qualitative indicator-generated regression equation contained three indicators, namely enhanced homogeneity, diameter line expansion and peak intensity grading, which demonstrated prediction accuracy for benign and malignant breast tumor lumps of 91.8%; the quantitative indicator-generated regression equation only contained one indicator, namely the relative peak intensity, and its prediction accuracy was 61.5%. The corresponding areas under the ROC curve for qualitative and quantitative analyses were 91.3% and 75.7%, respectively, which exhibited a statistically significant difference by the Z test (P<0.05). Conclusions: The ability of CEUS qualitative analysis to identify breast tumor lumps is better than with quantitative analysis.

Evaluation of Air Ion According to the Type of Ridge in Urban Park -Focused on Tangeumdae Park in ChungJu- (도심 산지형 공원 능선부 식생유형에 따른 공기이온 평가 - 충주시 탄금대 공원을 대상으로 -)

  • Kim, Jeong Ho;Lee, Sang Hoon;Yoon, Yong Han
    • Korean Journal of Environment and Ecology
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    • v.33 no.5
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    • pp.587-595
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    • 2019
  • This study analyzed the influence of the environmental factor of each vegetation type in an urban, mountainous park (Tangeumdae Park in Chungju) on air ion. The measuring points were divided according to the tree species, diameter at breast height, crown density, and layered structure, and the meteorological factors and the air ion were measured. The results of the measurement showed the average generation of positive ions of $610.90{\pm}50.27ea/cm^3$, the average generation of negative ions of $723.58{\pm}64.25ea/cm^3$, and the air ion index of $1.19{\pm}0.10$. The results of the analysis, according to the vegetation type, are as follows. Firstly, the air ion varied according to the species, the chest diameter at breast height, and the layered structure, and was analyzed to be statistically significant. Secondly, the air ion and the vegetation type showed a positive correlation with the species, diameter at breast height, crown density, and layered structure. The cation showed a negative correlation with the species, diameter at breast height, and the crown density, and the anion showed a positive correlation with the species, the diameter at breast height, crown density, and layered structure. Thirdly, the ion index in ridges had a higher correlation with the vegetation type than the meteorological factors. In detail, the correlation was higher in the species > layered structure > crown density > diameter at breast height. This study had the limitation of evaluating air ions in the ridge. Therefore, future studies on air ion should consider both terrain structure and vegetation type and analyze the seasonal changes and comparison.

A Study on the Relation between Working Time and Tree Formal Characteristics (임업(林業)에서의 순수작업시간(純粹作業時間)과 임목형상조건(林木形狀條件)과의 관계연구(關係硏究))

  • Kang, Gun-Uh
    • Journal of Korean Society of Forest Science
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    • v.78 no.4
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    • pp.381-395
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    • 1989
  • The main purpose of this research is to provide scientific informations about standard wage and performance tariffs in forest management with special reference to working time for thinning. To identify relationships between net working time and tree characteristics, three geographically different sample plots were established at Yangsan, Bongpyung and Jinan and 460 oaks, 372 Japanese larches, 232 red pine and 240 pitch pine mere selected at each sample plots. The results of statistical analysis using multiple regression are as follows ; 1. Five independent variables of breast height diameter(DBH), mid-diameter(MD) large end diameter(LD), log-length(L), No. of branches(NOB) were stable independent of worker and tree species. 2. Comparing correlation coefficient of five independent variables, the best predictive variables, breast height diameter and No. of branches, were selected. Breast height diameter and No. of branches were identified as the most important independent variables in terms of effect on the dependent variable of the working time. 3. Comparing coefficient of determination (Rp) and residual mean square (MSEp), the best Linear regression equation for each tree species was selected as follower : $WT=a+b1{\times}NOB+b2{\times}DBF$ 4. Proportion of hang-up time to total working time in thinning were 66% in oak stand, 74%, in Japanese larch stand, 55%, in red pine stand and 52% in pitch pine stand, respectively. 5. Based on the best regression equation, a table of working time was made by strata of number of branches and breast height diameter. 6. Total working time using the best regression equation in Table 5 can be predicted in terms of felling time, limbing time, hang-up time, i.e., total working time increases by 11 to 13 seconds with every 1 centimeter increase in breast height diameter from 7 to 16 centimeter.

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Analysis of the Location Environment of the Sub-alpine Coniferous Forest in National Parks Using GIS - Focusing on Abies koreana - (GIS를 활용한 국립공원 아고산대 침엽수림의 입지환경 분석 - 구상나무를 대상으로 -)

  • Kim, Tae-Geun;Oh, Jang-Geun
    • Korean Journal of Ecology and Environment
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    • v.49 no.3
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    • pp.236-243
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    • 2016
  • It was a case study to use as a basic data for efficient the preservation and management of subalpine coniferous forest in national parks. It is based on inhabitation condition of 210 individuals of Abies koreana Wilson that was found through local investigation in the sub-alpine zone of Jirisan National Park and Songnisan National Park. It analyzed the effect of the geographical location and topographical features, which are the basics of location environment, on the growth of A. koreana. The variables related to the growth of A. koreana are tree height and diameter at breast height. Topographical features include geographical longitude, altitude above sea level, slope of the mountains, aspect that describes the direction in which a slope faces and topographical wetness index. Topographical features were extracted through GIS spatial analysis. It used canonical correlation analysis to estimate whether the two variables groups have related to each other and how much they are related, if any, and estimated the effect of the geographical and topographical features on the growth structure of A. koreana using multiple regression analysis. The tree height and diameter at breast height that represent the growth structure of A. koreana show greater relation to geographical latitude distribution than topographical feature and the geographical and topographical factors show greater relation to diameter at breast height than tree height. The growth structure's variable and geographical and topographical variable of A. koreana have meaningful relation and the result shows that geographical and topographical variables explain 18.1% of the growth structure. The variables that affect the diameter at breast height of A. koreana are geographical latitude, topographical wetness index, aspect and altitude, which are put in order of statistical significance. The higher the latitude is, the smaller the diameter at breast height. Depending on the topographical feature, it becomes bigger. The variable that affects the tree height is topographical wetness index, which was the only meaningful variable. Overall, the tree height and diameter at breast height that are related to the growth structure of A. koreana are affected by geographical and topographical feature. It showed that the geographical feature affected it the most. Especially the effect of water among the topographical features is expected to be bigger than the other topographical factors. Based on the result, it is expected that geographical and topographical feature is an important factor for the growth structure of A. koreana. Even though it considered only the geographical and topographical features and used spatial analysis data produced by GIS, the research results will be useful for investigating and researching the growth environment of coniferous forest inhabiting in sub-alpine zone of national parks and are expected to be used as basic data for establishing measures to efficiently manage and preserve evergreen needleaf tree such as A. koreana.

Comparison of the second and third intercostal spaces regarding the use of internal mammary vessels as recipient vessels in DIEP flap breast reconstruction: An anatomical and clinical study

  • Seong, Ik Hyun;Woo, Kyong-Je
    • Archives of Plastic Surgery
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    • v.47 no.4
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    • pp.333-339
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    • 2020
  • Background The purpose of this study was to compare the anatomical features of the internal mammary vessels (IMVs) at the second and third intercostal spaces (ICSs) with regard to their use as recipient vessels in deep inferior epigastric artery perforator (DIEP) flap breast reconstruction. Methods A total of 38 consecutive DIEP breast reconstructions in 36 patients were performed using IMVs as recipient vessels between March 2017 and August 2018. The intraoperative findings and postoperative complications were analyzed. Anatomical analyses were performed using intraoperative measurements and computed tomography (CT) angiographic images. Results CT angiographic analysis revealed the mean diameter of the deep inferior epigastric artery to be 2.42±0.27 mm, while that of the deep inferior epigastric vein was 2.91±0.30 mm. A larger mean vessel diameter was observed at the second than at the third ICS for both the internal mammary artery (2.26±0.32 mm vs. 1.99±0.33 mm, respectively; P=0.001) and the internal mammary vein (IMv) (2.52±0.46 mm vs. 2.05±0.42 mm, respectively; P<0.001). Similarly, the second ICS was wider than the third (18.08±3.72 mm vs. 12.32±2.96 mm, respectively; P<0.001) and the distance from the medial sternal border to the medial IMv was greater (9.49±2.28 mm vs. 7.18±2.13 mm, respectively; P<0.001). Bifurcations of the IMv were found in 18.4% of cases at the second ICS and in 63.2% of cases at the third ICS. Conclusions The IMVs at the second ICS had more favorable anatomic features for use as recipient vessels in DIEP flap breast reconstruction than those at the third ICS.

Correlation between MR Image-Based Radiomics Features and Risk Scores Associated with Gene Expression Profiles in Breast Cancer (유방암에서 자기공명영상 근거 영상표현형과 유전자 발현 프로파일 근거 위험도의 관계)

  • Ga Ram Kim;You Jin Ku;Jun Ho Kim;Eun-Kyung Kim
    • Journal of the Korean Society of Radiology
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    • v.81 no.3
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    • pp.632-643
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    • 2020
  • Purpose To investigate the correlation between magnetic resonance (MR) image-based radiomics features and the genomic features of breast cancer by focusing on biomolecular intrinsic subtypes and gene expression profiles based on risk scores. Materials and Methods We used the publicly available datasets from the Cancer Genome Atlas and the Cancer Imaging Archive to extract the radiomics features of 122 breast cancers on MR images. Furthermore, PAM50 intrinsic subtypes were classified and their risk scores were determined from gene expression profiles. The relationship between radiomics features and biomolecular characteristics was analyzed. A penalized generalized regression analysis was performed to build prediction models. Results The PAM50 subtype demonstrated a statistically significant association with the maximum 2D diameter (p = 0.0189), degree of correlation (p = 0.0386), and inverse difference moment normalized (p = 0.0337). Among risk score systems, GGI and GENE70 shared 8 correlated radiomic features (p = 0.0008-0.0492) that were statistically significant. Although the maximum 2D diameter was most significantly correlated to both score systems (p = 0.0139, and p = 0.0008), the overall degree of correlation of the prediction models was weak with the highest correlation coefficient of GENE70 being 0.2171. Conclusion Maximum 2D diameter, degree of correlation, and inverse difference moment normalized demonstrated significant relationships with the PAM50 intrinsic subtypes along with gene expression profile-based risk scores such as GENE70, despite weak correlations.

Vegetation Structures Analysis and Management Plan Proposal for Seokseong Fortress in Buyeo-Gun (부여 석성산성의 식생 구조 및 관리 방안)

  • Yee, Sun;Lee, Donghyuk;Lee, Jihye;Song, Hokyung
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.12 no.4
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    • pp.23-33
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    • 2009
  • Vegetation structure of Seokseong fortress in Buyeo-Gun was investigated to suggest a desirable management proposal. Communities by phytosociological method were classified into Pinus rigida-Pinus densiflora community and Quercus variabilis community. The importance value of Pinus rigida, Pinus densiflora, Quercus variabilis, Pinus thunbergii, and Quercus acutissima were 127.06, 70.29, 69.63, 12.39 and 8.57. According to breast diameter analysis results, it is expected that the importance value of Pinus rigida, Pinus densiflora, and Quercus variabilis will be continuously increased. It should be prepared that vegetation management plan over the castle wall should be considered before the repair or restoration of castle wall. Vegetation management around castle wall should be carried out according to the mid or long-term plan and it would be needed to consider the gradual changes from planted Pinus rigida to the historical vegetation of Pinus densiflora.

The Oncological Safety of Nipple-Sparing Mastectomy: A Systematic Review of the Literature with a Pooled Analysis of 12,358 Procedures

  • Headon, Hannah Louise;Kasem, Abdul;Mokbel, Kefah
    • Archives of Plastic Surgery
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    • v.43 no.4
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    • pp.328-338
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    • 2016
  • Nipple-sparing mastectomy (NSM) is increasingly popular as a procedure for the treatment of breast cancer and as a prophylactic procedure for those at high risk of developing the disease. However, it remains a controversial option due to questions regarding its oncological safety and concerns regarding locoregional recurrence. This systematic review with a pooled analysis examines the current literature regarding NSM, including locoregional recurrence and complication rates. Systematic electronic searches were conducted using the PubMed database and the Ovid database for studies reporting the indications for NSM and the subsequent outcomes. Studies between January 1970 and January 2015 (inclusive) were analysed if they met the inclusion criteria. Pooled descriptive statistics were performed. Seventy-three studies that met the inclusion criteria were included in the analysis, yielding 12,358 procedures. After a mean follow up of 38 months (range, 7.4-156 months), the overall pooled locoregional recurrence rate was 2.38%, the overall complication rate was 22.3%, and the overall incidence of nipple necrosis, either partial or total, was 5.9%. Significant heterogeneity was found among the published studies and patient selection was affected by tumour characteristics. We concluded that NSM appears to be an oncologically safe option for appropriately selected patients, with low rates of locoregional recurrence. For NSM to be performed, tumours should be peripherally located, smaller than 5 cm in diameter, located more than 2 cm away from the nipple margin, and human epidermal growth factor 2-negative. A separate histopathological examination of the subareolar tissue and exclusion of malignancy at this site is essential for safe oncological practice. Long-term follow-up studies and prospective cohort studies are required in order to determine the best reconstructive methods.