• Title/Summary/Keyword: Break of Relationship

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Effects of Several Heavy Metals on the Frequencies of Sister Chromatid Exchanges and Chromosomal Aberrations in Human Lymphocytes (일부 중금속이 인혈배양 임파구의 염색체이상 및 자매염색분체교환에 미치는 영향)

  • Jung, Chae-Deuk;Lee, Jeong-Sang;Koh, Dai-Ha;Ki, No-Suk;Hwang, In-Dam
    • Journal of Preventive Medicine and Public Health
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    • v.22 no.1 s.25
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    • pp.116-124
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    • 1989
  • To assay the cytogenetic toxicity of $NiCl_2,\;K_2Cr_2O_7CdCl_2,\;and\;HgCl_2$, the frequencies of sister chromatid exchanges(SCEs) and chromosomal aberrations were observed in the metaphase chromosomes of the human lymphocytes which were cultured with above materials. The frequencies of SCEs are dose-dependently increased by all materials in this experiment. Chromosomal aberrations, especially gap and break, are increased by the nickel and chromic compounds, while not significantly increased by the cadmium and mercurial compounds. This results indicate the dose dependent relationship between the frequencies of SCEs and the concentrations of the heavy metals, but the increasing rates of the SCEs induced by the heavy metals are less sensitive than other mutagens or carcinogens which were confirmed.

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Prediction of Loss of Life in Downstream due to Dam Break Flood (댐 붕괴 홍수로 인한 하류부 인명피해 예측)

  • Lee, Jae Young;Lee, Jong Seok;Kim, Ki Young
    • Journal of Korea Water Resources Association
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    • v.47 no.10
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    • pp.879-889
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    • 2014
  • In this study, to estimate loss of life considered flood characteristics using the relationship derived from analysis of historical dam break cases and the factors determining loss of life, the loss of life module applying in LIFESim and loss of life estimation by means of a mortality function were suggested and applicability for domestic dam watershed was examined. The flood characteristics, such as water depth, flow velocity and arrival time were simulated by FLDWAV model and flood risk area were predicted by using inundation depth. Based on this, the effects of warning, evacuation and shelter were considered to estimate the number of people exposed to the flood. In order to estimate fatality rates based on the exposed population, flood hazard zone is assigned to three different zones. Then, total fatality numbers were predicted after determining lethality or mortality function for each zone. In the future, the prediction of loss of life due to dam break floods will quantitatively evaluate flood risk and employ to establish flood mitigation measures at downstream applying probabilistic flood scenarios.

Family Program Development Direction for Stepfamily Relationship Enhancement with Adolescents at Home -Focusing on the Relation between Stepparents and Stepchildren- (재혼가족 관계향상을 위한 프로그램 개발방향 -새부모·새자녀관계를 중심으로-)

  • Kim, Hyo-Soon
    • The Journal of the Korea Contents Association
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    • v.15 no.2
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    • pp.262-280
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    • 2015
  • The number of stepfamilies is rapidly growing in our society according to social changes. So family programs especially for stepfamily relationship enforcement with adolescents at home are needed. The purpose of this study is to investigate the direction of family programs for enforcing the stepfamily relationship between stepparents and stepchildren. For the purpose, case studies from those stepfamilies were analyzed through qualitative interviews and early developed program contens were referred. Based on discussion mentioned above, program development direction for stepfamily relationship enforcement is not only dealing with difficulties of stepfamilies in their early remarriage but also emphasizing their advantages. In conclusion, this program development direction expected stepfamilies to resolve their problems and to prevent their family break up as well as to deliver practical benefits.

The Effects of Entrepreneurial Intention on Planned Happenstance Skill of Career-Breaking Women: Focusing on Moderating Effects of Successful Role Models and Social Support Forces (경력단절여성의 계획된 우연역량이 창업의지에 미치는 영향에 관한 연구: 개인 환경요인의 조절효과를 중심으로)

  • Chung, Inkoo;Yang, Dongwoo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.15 no.5
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    • pp.129-143
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    • 2020
  • Recently, Start-ups has been emphasized as part of a career-breaking women returning to society policy. To this Policy, the relationship between the planned happenstance skills and the entrepreneurial intentions of a career-breaking woman was investigated, and the successful role model as an individual environmental factor and the moderating effect of social support forces was verified. The results of the survey analysis of 139 women who have experienced career cut-offs in the metropolitan area and Dae-gu and Gyeong-buk are as follows; First, the planned happenstance skills of career-breaking women affect a positive effect on the entrepreneurial intentions. Second, it was found that the moderating effect of the successful role model does not appear in the relationship between the planned happenstance skills of a career-breaking woman and the entrepreneurial intentions. Third, it was found that there was no moderating effect of the social support forces in the relationship between the planned happenstance skills and the entrepreneurial intentions of a career-breaking woman. Last, It was found that the entrepreneurial intentions, which is a personal psychological characteristic for career-breaking women is more directly affected than personal environments. In order to increase career-breaking women's the entrepreneurial intentions, it is necessary to develop psychological skill-building programs which can enhance the accessibility of start-ups and raise the perception of Start-ups. In addition, it is necessary to continuously expand exposure opportunities such as role models and success stories which succeeded in starting a business after a career break and to expand social support forces that can help with courage, advice, and change management to discover opportunities of start-ups.

An Empirical Study on the Relationship between the Key Success Factors and the Usage Effect of the e-Sports Business (e스포츠 비즈니스의 주요 성공요인과 이용효과와의 관계에 관한 실증연구)

  • Lee, Kyung-Jin;Kim, Chang-Su
    • The Journal of Information Systems
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    • v.20 no.2
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    • pp.109-134
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    • 2011
  • The purpose of this paper is to present an overview of the characteristics of the e-sports business at a crucial point in the era of information and knowledge. That is, an investigation was conducted surrounding the key success factors of e-sports as a newly growing industry, and the relationship between the key success factors and the usage effect. In order to do this, the key success factors were extracted from interviews with e-sports experts in conjunction with a survey that was conducted to gather empirical data. The key points of the statistical analysis of the survey are as follows. First, the success factors of a policy do not have a significant effect on the usage. Second, some administrative success factors of the e-sports business include the distribution of e-sports in the form of franchise chain, the establishment of policies to prevent the excellent members of e-sports from seceding, making a good impression as a high-class sport, the frequent notice of the break-even point, and educating people on how to use the e-sports machine. Third, the development and distribution of excellent e-sports software was analyzed as a technical success factor of the e-sports business. Finally, there is no doubt that results of this study can be used to facilitate the growth of the e-sports business as a new industry related to the IT industry.

The Impact of Difference of Linkages between Manufacturing Strategy and Action Plans - An Empirical Comparison of U.S. and Korean Manufacturers -

  • Lee, Sang-Gun;Lee, Choong-Kwon;Park, Boo-Ho
    • Journal of Korea Society of Industrial Information Systems
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    • v.5 no.4
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    • pp.81-93
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    • 2000
  • It is important to find the competitive priority, which makes a great contribution to the action plans. The reason is that this makes it possible to provide Korean manufacturers with effective behavioral model to break through the depression after 1997'financial crisis in Korea. Focused priority has become a focus of organizations faced with the need to survive in a highly uncertain business environment characterized by rapid technological change, global competition, and demanding customers. Many believe that better linkages of priority and action plans are fundamental to surviving in the world market. However, there was little previous research dealing with the relationship between the strategic priority and action plans in the view of competitive weapon. This study presents empirical findings on differences between U.S. and Korean manufacturing approach to relationship of priority and plans. Specially, Korean manufacturers are eager for good model to overcome depression of 1997' financial crisis in Korea. Data was collected as part of the Manufacturing Futures Project completed in 1996. The results indicate that U.S. manufacturers maintain focused linkages from priority to action plans than do Korean manufacturers.

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Changes in Subjective Symptom, Tear Film Stabilization and Blinking Rates when Wearing RGP Lenses with Different Polishing Conditions for Certain Period of Time (연마상태가 다른 RGP렌즈의 일정기간 착용 시 렌즈착용자의 자각적 증상, 눈물막 안정 및 순목횟수 변화)

  • Park, Mijung;Kim, Hyo Gyum;Bae, Jun Seob;Park, Jung Ju;Kim, So Ra
    • Journal of Korean Ophthalmic Optics Society
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    • v.19 no.1
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    • pp.31-42
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    • 2014
  • Purpose: The present study was conducted to investigate the effect of the physical properties of RGP lens induced by lens polishing on the actual wearer's subjective comfort, the tear film break-up time and the blinking rate as a follow-up study that revealed the relationship between the lens physical properties during lens manufacturing and lens wearer's factors. Methods: RGP lenses made from the three different polishing conditions (25, 50 and 100 seconds) were applied on 28 eyes of 17 subjects, aged 20 to 29 years, without any known disease and surgical history in the eyes. While the subjects were asked to wear the RGP lenses longer than a week, the questionnaire for the comfortability was administered everyday. Subjective and objective tear break-up time and blinking rate of the wearers were further measured. Results: The wearer's subjective comfortability showed some difference in the type of discomfort and satisfaction score according to the polishing status when wearing RGP lenses made from different polishing conditions longer than a week, and a bigger difference in satisfaction score induced by polishing condition was especially shown in experienced RGP lens wearer rather than un-experienced wearer. In the case of RGP lens wearer compared with the ones without the wearing experience, as the wearing time increased subjective and objective tear break-up time were increased and the blinking rate was decreased. However, subjective and objective tear break-up time were tended to decrease with even longer wearing time when wearing the RGP lens made from the polishment for 100 seconds. Conclusions: These results confirmed that the optimization of physical properties of the lens may not give the same effect on the wearer's subjective and objective symptoms and other factors when actual wearing. From the results, it can suggest that the success rate of RGP lens wear may be changed by physiological factors such as the stabilization of wearer's tear film, comfortability and lens wearing experience when wearing RGP lens based on 'The manufacturing standard for soft contact lens/hard contact lens' provided by Korea Food and Drug Administration.

Kinetics and Mechanism of the Pyridinolysis of Ethylene Phosphorochloridate in Acetonitrile

  • Barai, Hasi Rani;Lee, Hai-Whang
    • Bulletin of the Korean Chemical Society
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    • v.32 no.12
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    • pp.4347-4351
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    • 2011
  • The nucleophilic substitution reactions of ethylene phosphorochloridate (2) with X-pyridines are investigated kinetically in acetonitrile at $-20.0^{\circ}C$. The free energy correlations for substituent X variations in the nucleophiles exhibit biphasic concave upwards with a break point at X = 3-Ph. Unusual positive ${\rho}_X$ (= +2.49) and negative ${\beta}_X$ (= -0.41) values are obtained with the weakly basic pyridines, and rationalized by the isokinetic relationship with isokinetic temperature at $t_{ISOKINETIC}=6.6^{\circ}C$. The pyridinolysis rate of 2 with a cyclic five-membered ring is forty thousand times faster than its acyclic counterpart (3: diethyl chlorophosphate) because of great positive value of the entropy of activation of 2 (${\Delta}S^{\neq}$ = +49.2 eu) compared to negative value of 3 (${\Delta}S^{\neq}$ = -44.1 eu) over considerably unfavorable enthalpy of activation of 2 (${\Delta}H^{\neq}=28.4\;kcal\;mol^{-1}$) compared to 3 (${\Delta}H^{\neq}=6.3\;kcal\;mol^{-1}$). Great enthalpy and positive entropy of activation are ascribed to sterically congested transition state (TS) and solvent structure breaking in the TS. A concerted mechanism involving a change of nucleophilic attacking direction from a frontside attack with the strongly basic pyridines to a backside attack with the weakly basic pyridines is proposed.

Convergence relationship of BMI, Sleep time and Experience of oral disease in Adolescents (청소년의 BMI, 수면시간과 구강질환경험과의 관련성 융합연구)

  • Park, Sin-Young
    • Journal of the Korea Convergence Society
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    • v.11 no.10
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    • pp.387-392
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    • 2020
  • This study was to investigate the relationship of BMI, sleep time and experience of oral diseases in adolescents. We want to help develop basic data for improving oral health of adolescents. According to the sample design of the Youth Health Behavior online survey, a total of 57,303 adolescents were analyzed for frequency of composite samples, x2-test of composite samples, and logistic regression of composite samples, and the IBM SPSS Statistics 20.0 program was used and the significance level was 0.05. Results, BMI was associated with bad breath, and sleep time was associated with tooth break, pain, bleeding, and bad breath. Therefore, BMI and sleep time should be considered for the management and prevention of oral diseases in adolescents.

The Relationship between Childcare Philosophy and Architectural Space of Communal Childcare Cooperative Nurseries (공동육아 협동조합 어린이집 보육철학과 건축공간의 관계성)

  • Yoo, Myoung-Hee
    • Journal of the Korean Institute of Educational Facilities
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    • v.19 no.2
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    • pp.41-50
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    • 2012
  • This study aims to analyze chlidcare philosophy and the architectural characteristics of communal childcare cooperative nurseries(parent cooperative childcare facilities), and also to examine their mutual relationship. The communal childcare cooperative is an ideal childcare method to break away from employee-supported childcare system and cooperatively solve childcare problems in the family community system. The child-rearing philosophy of the communal childcare can bring spontaneous and creative development amidst 'daily life' and 'play' by switching from knowledge and skill-oriented education and puts an emphasis on physical environments in child's growth. The features of architecture related the childcare philosophy derived from this study are as follows: the way of participation and self-help, the extension of spatial scope and focuses on outside space, architecture of house-like residence rather than educational facility, spatial 'overlapping' focusing on transitional space and multi-purpose space rather than spatial partitions, the pursuit of creativity through play is realized in the incompletion and unspecification of space evolving over time.