• Title/Summary/Keyword: Brain-behavior relationship

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The Meta-analysis on Variables related to Ego Integrity of Elderly in Korea (한국노인의 자아통합감 관련변인에 대한 메타분석)

  • Kim, Ilsik;Kim, Gyeryung;Seo, Hochan
    • 한국노년학
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    • v.37 no.3
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    • pp.637-653
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    • 2017
  • Meta-analysis was conducted on 56 studies published in Korea until April 2017 to systematically integrate factors of ego integrity of the elderly. The variables related to ego integrity were divided into 6 groups of variable, and the effect sizes were computed for each variable of their groups. The analysis results are as follows. First, the total effect size showed the middle effect size, and the effect size according to the variable group showed the largest effect size for the positive psychological variable group, followed by the negative psychological variable, the physical variable, the familial variable, the social variable and the demographic variable. Second, the largest effect size of the sub-variables on the each individual variable group showed positive psychological variable was life quality, negative psychological variable was depression, physical variable was health behavior, familial variable was children relationship, social variable was social support and demographic variable was economic status. As described above, suggesting that these variables may have a strong influence on ego integrity among the variables related to ego integrity because the quality of life, life satisfaction and depression were shown as the largest effective variables related to ego integrity.

Songwriting as Therapy with Pediatric Patients Undergoing Cancer Treatment (소아암환자들을 위한 노래 만들기(Songwriting)의 음악치료적 적용)

  • Hwang, Jee Hye
    • Journal of Music and Human Behavior
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    • v.5 no.2
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    • pp.67-92
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    • 2008
  • The purpose of this study is to give an overview of the clinical process of songwriting with pediatric patients undergoing cancer treatment. Many literatures have proved that music therapy aids patients during their cancer treatment to relax, reduce anxiety and feelings of isolation, and promote self-esteem and quality of life and so on. However, among music therapy methods, I found songwriting proved to be very effective method. By using songwriting as therapy with pediatric patients undergoing cancer treatment, songwriting helped patients express difficulties of dealing emotionally with their illness and ongoing aggressive and invasive treatments. Also the process of songwriting established trust and relationship between therapist and patient which promoted normalization of hospital environment. In my case study, patient N has expressed her feelings and thoughts through writing songs about her current life which revolved around treatment of her brain tumor. Moreover, patient N found her creativity and developed ways of getting touch with her inner strength.

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The Study of Cognitive Function and EEG Spectrum Difference between Allergic Rhinitis and Normal Children (뇌파측정을 이용한 비염 환아와 정상아의 주의집중력에 관한 연구)

  • Lee, Nam-Yeol;Kim, Yun-Hee;Han, Jae-Kyung
    • The Journal of Pediatrics of Korean Medicine
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    • v.21 no.2
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    • pp.1-12
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    • 2007
  • Objectives : Allergic children have known to have multiple behavior problems. Among them, attentional ability disorder is one of the most common problems. This study is to examine relationship between learning ability and allergic rhinitis by analyzing EEG status of children. Methods : We analyzed cognitive functions of two different children groups; 21 children with allergic rhinitis and 19 normal children with CANS 3000(Central & Autonomic Nervous System, LAXTHA Inc., Korea), cognitive functions assessment program by EEG. Results : 1. According to mean active EEG rhythm of Theta, Alpha, SMR, M-beta, there were no significant difference between allergic rhinitis and the normal group. 2. According to mean active EEG rhythm of right H-beta, Gamma wave allergic rhinitis group's value was significantly higher than that of the normal group. 3. According to mean cognitive strength, response, concentration, left / right brain activity and learning ability score, there were no significant difference between allergic rhinitis and the normal group. 4. According to mean workload score, allergic rhinitis group's value was significantly higher than that of the normal group. Conclusions : It is likely that allergic rhinitis group, which showed relatively high frequency EEG rhythm, is more fragile to stress and less active on mental processing. Along side with physical examination, psychological assessment should also be conjugated on treating children with allergic rhinitis.

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Alcohol Withdrawal and Serum Nitrite Concentration (알코올 금단과 혈중 아질산염 농도)

  • Lee, Boung Chul;Son, Hyun-Gyun;Choi, Ihn-Geun
    • Korean Journal of Biological Psychiatry
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    • v.11 no.1
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    • pp.33-39
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    • 2004
  • Objective:Nitric oxide(NO) has been known to be associated with tolerance and preference to alcohol. It has also been known to affect various alcohol drinking behavior, alcohol withdrawal symptoms and alcohol- induced brain damage. The purpose of this study was to determine the difference, among alcohol dependence group, alcohol drinking group and abstinence group, in serum concentration of nitrite, a stable metabolite of NO, and it's relationship to clinical and biochemical markers of alcoholism. Methods:Forty subjects diagnosed as alcohol dependence according to DSM-IV diagnostic criteria were evaluated for the clinical characteristics and biochemical markers of alcohol dependence including nitrite with their CIWA-Ar scores checked just after admission. Thirty-nine healthy controls were also evaluated, divided into twenty-three alcohol drinking group and sixteen abstinence group. Clinical characteristics were evaluated by CIWA-Ar, CAGE and AUDIT questionnaires. Aspartate aminotransferase(AST), alanine aminotransferase (ALT), gamma glutamyltransferase(GGT) and mean corpuscular volume(MCV) were used as the biochemical markers of alcohol dependence. Serum nitrite concentrations were measured by Griess reaction. Results:1) The concentrations of nitrite in alcohol dependence patients were not different from those in the control subjects. 2) There were no significant association between the nitrite concentrations and the CIWA-Ar scores in alcohol dependence patients. 3) Nitrites are significantly increased in alcohol dependence group and alcohol drinking group compared with abstinence group. Conclusions:These findings suggest that serum nitrite concentration has no relation with alcohol withdrawal symptoms, but alcohol drinking increases serum nitrite concentration influenced by general condition of the body.

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The Neurophysiological Approaches in Animal Experiments (신경생리학적(神經生理學的) 동물실험(動物實驗))

  • Cheon, Jin-Sook
    • Korean Journal of Biological Psychiatry
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    • v.5 no.1
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    • pp.3-16
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    • 1998
  • The neurophysiological study has been widely used in search of the relationship between brain and behavior. The basic techniques for the animal experiments of this kind such as stereotaxic techniques, lesioning methods, the methods of electrical stimulation and recording, and confirmation of histological location were briefly reviewed. Nevertheless, the importance of complementary neurochemical, neuroanatomical and behavioral studies can not be neglected.

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Features and implication of new physical activity guidelines (새 신체활동기준의 동향과 함의)

  • Koh, Kwang Wook
    • Korean Journal of Health Education and Promotion
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    • v.35 no.5
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    • pp.17-24
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    • 2018
  • Objectives: After many national physical activity guidelines have established, recent changes are deep and rapid. So the major features and implication to reverse worsening Korean physical activity indicator is desprate but related knowledge and informations are few. So review of recent features and implications of new physical activity guidelines have made. Methods: National physical activity guidelines of advanced countries were searched through snowballing methods. Major features were described according to the nation. Implication were drew through discussion for Korean realitiy. Results: New Australian physical activity and sedentary behaviour guideline explicitly included sedentary behaviour. The age in the guideline expanded to early years. Canada also presented 24-hour movement guidelines to early years. The second generation of the physical activity guidelines reflects the extensive amount of new knowledge. New aspects include discussions of additional health benefits related to brain health, additional cancer sites, and fall-related injuries; immediate and longer term benefits for how people feel, function, and sleep; further benefits among older adults and people with additional chronic conditions; risks of sedentary behavior and their relationship with physical activity; elimination of the requirement for physical activity benefits to occur in bouts of at least 10 minutes; and tested strategies that can be used to get the population more active. Conclusions: The most important message from the new guidelines is that the greatest health benefits accrue by moving from no, to even small amounts of, physical activity. Multiple studies demonstrate that the steepest reduction in disease risk occurs at the lowest levels of physical activity. People need to understand that even small amounts of physical activity are beneficial and that reductions in the risk of disease and disability occur by simply getting moving. So various evidence based proven strstegies are needed in Korea including workforce training.

Gray Matter Volume Reductions Were Associated with TPH1 Polymorphisms in Depressive Disorder Patients with Suicidal Attempts

  • Lee, Sang Min;Lee, Soyoen;Kang, Won Sub;Jahng, Geon-Ho;Park, Hae Jeong;Kim, Su Kang;Park, Jin Kyung
    • Psychiatry investigation
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    • v.15 no.12
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    • pp.1174-1180
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    • 2018
  • Objective Structural changes of brain areas have been reported in depressive disorder and suicidal behavior (SB), in which TPH1 also has been known as a promising candidate gene. We investigated gray matter volume (GMV) differences, TPH1 rs1800532 and rs1799913 polymorphisms previously found to be associated with depressive disorder and SB, and the relationship between the two markers. Methods Thirteen depressive disorder patients with suicidal attempts (SA) and twenty healthy controls were included. We examined GMV differences using a voxel-based morphometry and regions of interest analysis. Direct sequencing was used for genotyping. Results The patients showed significant GMV reduction in left cerebral region including middle frontal gyrus, inferior frontal gyrus, and anterior cingulate cortex; in right middle temporal gyrus; in left cerebellar tonsil; and in right cerebral region including precentral gyrus and postcentral gyrus (corrected p<0.005). The right precentral and postcentral gyri GMV values of AA and CA genotypes patients were significantly decreased compared to those of CC genotype subjects (corrected p=0.040). Conclusion These findings show the possibility that both GMV reductions and TPH1 rs1800532/rs1799913 A allele may be involved in the pathogenesis of depressive disorder patients with SA.

Effects of Estrogen on the Transcriptional Activities of Catecholamine Biosynthesizing Enzymes in the Brain and Adrenal Gland of Ovariectomized Rats (난소 절제 흰쥐의 뇌와 부신에서의 Catecholamine Biosynthesizing Enzyme들의 전사에 미치는 Estrogen의 효과)

  • 유경신;이종화;최돈찬;이성호
    • Development and Reproduction
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    • v.6 no.2
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    • pp.117-122
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    • 2002
  • Dopamine(DA), norepinephrine(NE), and epinephrine(E) belong to a class of neurotransmitters known as catecholamine (CA) which are synthesized and secreted by mammalian brain and adrenal medulla. CA regulate several behavior patterns connected with breeding, and regulate GnRH-gonadotropin hormone axis' vitality between hypothalamus-pituitary gland linking with reproduction freeze. The present study examined effects of sex steroid hormone on the transcriptional activities of CA biosynthesis enzymes, tyrosine hydroxylase(TH), dopamine $\beta$ -hydroxylase(DBH), and phenylethaolamine-N-methyl transferase(PNMT). Mature female rats were ovariectomized(OVX) and implanted with 17 $\beta$-estradiol(E$_2$: 500 $\mu\textrm{g}$/ml) or sesame oil. Forty-eight hours after implantation all the animals were sacrificed. Total RNAs were extracted immediately and were applied to semi-quantitative reverse transcription-polymerase chain reaction(RT-PCR). The expression level of TH was appeared by hypothalamus > SNc> adrenal medulla orders in OVX+Oil group, and by SNc > hypothalamus) adrenal medulla orders in OVX+E$_2$ group. Treatment with E$_2$ significantly increased TH expression in SNc and adrenal medulla but in hypothalamus, the reduced TH expression was observed. The expression level of DBH was appeared by adrenal medulla > SNc > hypothalamus orders in OVX+Oil group and in OVX+E$_2$ group. Administration of E$_2$ significantly reduced DBH expression in SNc, and increased in adrenal medulla. Two cDNA products, large(PNMT1) and small(PMNTs) species of 110bp difference, were amplified in SNc and hypothalamus, but only PNMTs was observed in adenal medulla. The PNMTs expression level was in the order of adrenal medulla > hypothalamus > SNc in both OVX+Oil and OVX+E$_2$ group. The PNMTs expression in SNc and adrenal medulla was significantly increased byE$_2$. The present report demonstrated that estrogen effects on transcriptional activities for CA biosynthethic enzymes were tissue specific in adrenal medulla as well as different region of brain. These results suggest that it might be crucial relationship between the type of estrogen receptor and CA enzyme gene expression.

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TREATMENT OF DENTOFACIAL DEFORMITY PATIENT WITH CEREBRAL PALSY (뇌성 마비를 동반한 악안면 기형 환자의 치험례)

  • Kim, Ki-Ho;Park, Sung-Yeon;Yi, Choong-Kook
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.2 no.1
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    • pp.39-44
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    • 2006
  • Cerebral palsy(CP) is one of the most common motor disease, due to brain injury during fetal and neonatal development which results in neuromotor paralysis and associated neuromuscular symptoms. Features of CP include motor disability due to the lack of muscle control, often accompanied by sensory disorders, mental retardation, speech disorders, hearing loss, epilepsy, behavior disorders, etc. There are increasing chances of treatment of dental patients with cerebral palsy, as the occurrence of CP is increasing with the decrease in infant mortality and an increase in immature birth and premature birth and also, there is a trend to pursue of higher quality of life. Reports on the relationship between CP and maxillofacial deformity are uncommon, but it is well known that the unbalance and discontrol of the facial muscles, lip, tongue and the jaws leads to malocclusion and temporomandibular joint disorders, and statistics show that class 2 relationship of the jaws and open bite is frequently reported. However, it is difficult to perform maxillofacial deformity treatment, which consists of orthodontic treatment, maxillofacial surgery and muscle adaptation training, due to difficulties in communication and problems of muscle adaptation caused by difficulties in motor control which leads to a high recurrence rate. This case report is to trearment of maxillofacial deformity in CP patient. A 26 year old female patient came to the department with the chief complaint of prognathism of the mandible and facial asymmetry. According to the past medical history, she was diagnosed as cerebral palsy 1 week after birth, classified as GMFC, classII accompanied with left side torticollis. The patient's intelligence was moderate, and there were no serious problems in communication. For two years time, the patient underwent lingual frenectomy, pre-operation orthodontic treatment and then bimaxillary orthognathic surgery to treat mandibular prognathism and facial asymmetry followed by rehabilitatory exercise of facial muscle. After 6 months of follow up, there was a good result. This is to report to the typical signs and symptoms of DFD in CP patient and the limitation of the usual method of the treatment of DFD in CP patient with literature review.

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The Impact of Forest Therapy on Neuro-cognitive, Psychosocial, and Physiological Aspects of Adolescent Internet Addiction Risk Group (산림치유가 청소년 인터넷 중독 위험군의 신경인지, 심리사회, 그리고 생리적 측면에 미치는 영향)

  • Choi, Sam Wook;Mok, Jung Yeon;Kim, Min Soo;Chung, Ahn Soo;Han, Jin Woo;Woo, Jong Min;Kim, Ki Weon;Park, Bum-Jin
    • Journal of Korean Society of Forest Science
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    • v.104 no.2
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    • pp.277-284
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    • 2015
  • This study aims to evaluate the impact of forest therapy on neuro-cognitive, psychosocial, and physiological aspect of adolescent internet addiction risk group. We have classified potential and high risk user group as internet addiction risk group according to the criteria of Korean Internet Addiction Proneness Scale(K Scale). Based on the results of k-scale from the adolescents in metropolitan area from May to July 2013, 25 people were selected as Internet addiction risk group. We have randomized 13 participants joining forest therapy camp and 12 participants not joining one, and analyzed the change of the two groups with Continuous Performance, Kimberly S. Young, Connor-Davidson Resilience, Relationship Change Scale, heart rate variability and cortisol. Statistically significant changes were observedd in neuro-cognitive, psychosocial, and physiological variables, Through this study, we can consider that the therapy healing may relieve the level of internet addiction and can be an alternative to control emotional stability and impulsive behavior.