• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.6 no.6
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• pp.273-283
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• 2016

In this paper, the effect of neurofeedback training program on attention ability of ADHD children is studied. The main concept of a neurofeedback training program is a robot control with brain wave. To do this, Mindset(neurosky, ltd) was used as a brain wave measurement and lego NXT was used to a robot kit. The developed brain wave training program has a 12 chapter. Students meet a problem situation and they invent and make a problem solving robot with NXT kits. After that, they control the their own robot by their brain wave. Developed program was applied to 8 student who live in chunan area. To monitor a change of attention ability, attention behavior checklist, K-CBCL, CTRS-R, ADS were used. These checklist were recorded with before and after the program. The result shows that student attention ability is increase after the program in the most of the checklist.

• Korean Journal of Radiology
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• v.22 no.3
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• pp.395-404
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• 2021

Objective: To compare the utility of computed tomography perfusion (CTP) and three different 4-point scoring systems in computed tomography angiography (CTA) in confirming brain death (BD) in patients with and without skull defects. Materials and Methods: Ninety-two patients clinically diagnosed as BD using CTA and/or CTP for confirmation were retrospectively reviewed. For the final analysis, 86 patients were included in this study. Images were re-evaluated by three radiologists according to the 4-point scoring systems that consider the vessel opacification on 1) the venous phase for both M4 segments of the middle cerebral arteries (MCAs-M4) and internal cerebral veins (ICVs) (A60-V60), 2) the arterial phase for the MCA-M4 and venous phase for the ICVs (A20-V60), 3) the venous phase for the ICVs and superior petrosal veins (ICV-SPV). The CTP images were independently reviewed. The presence of an open skull defect and stasis filling was noted. Results: Sensitivities of the ICV-SPV, A20-V60, A60-V60 scoring systems, and CTP in the diagnosis of BD were 89.5%, 82.6%, 67.4%, and 93.3%, respectively. The sensitivity of A20-V60 scoring was higher than that of A60-V60 in BD patients (p < 0.001). CTP was found to be the most sensitive method (86.5%) in patients with open skull defect (p = 0.019). Interobserver agreement was excellent in the diagnosis of BD, in assessing A20-V60, A60-V60, ICV-SPV, CTP, and good in stasis filling (κ: 0.84, 0.83, 0.83, 0.83, and 0.67, respectively). Conclusion: The sensitivity of CTA confirming brain death differs between various proposed 4-point scoring systems. Although the ICV-SPV is the most sensitive, evaluation of the SPV is challenging. Adding CTP to the routine BD CTA protocol, especially in cases with open skull defect, could increase sensitivity as a useful adjunct.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3711-3717
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• 2013

Background: To assess the efficacy and tolerability of Cisplatin plus Gemcitabine combination in patients with brain metastases (BM) from breast cancer (BC). Materials and Methods: Eighteen BC patients with BM who were treated with Cisplatin plus Gemcitabine regimen between 2003-2011 were evaluated. Results: A median of 6 cycles of this regimen were received, in fifteen patients (83.3%) as first-line chemotherapy, in 2 as second-line and in 1 as third-line after diagnosis of BM. Dose reduction was performed in 11 (61.1%) patients; major reasons were neutropenia and leukopenia. Grade III neutropenia and Grade II trombocytopenia rates were 33.3% and 16.7% respectively. Overall response rate (ORR; complete+partial response rate) was 33.4% (n=6) for the entire study population; triple negative patients achieved an 66.6% ORR while hormone receptor (HR) positive patients had 25% and HER2 positive patients 12.5%. Median progression-free survival was 5.6 months (2.4-8.8 months, 95%CI) and longer in patients with triple negative breast cancer (TNBC) (median 7.4 months, 95%CI, 2.4-12.3 months) than the patients with other subtypes (median 5 months for HER2 positive and 3.6 months for HR positive patients). Median PFS of the patients with TNBC who received this regimen as first-line was 9.2 months (5.2-13.2 months, 95%CI). Conclusions: Cisplatin plus Gemcitabine may be a treatment option for patients with BM from breast cancer. Longer PFS and higher response rates are results that support the usage of this regimen especially for the triple negative subtype. However, further prospective and randomized trials are clearly required to provide more exact information.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.41 no.6
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• pp.61-67
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• 2004

We propose a new algorithm to generate additional training patterns using the brain-style information processing algorithm, that is, supervised and unsupervised learning models. This will be useful in the case that we do not have enough number of training patterns because of limitation such as time consuming, economic problem, and so on. We adopt the independent component analysis as an unsupervised model for generating exempalr patterns and multilayer perceptions as supervised models for verifying usefulness of the generated patterns. After statistical analysis of the proposed pattern generation algorithm, we verify successful operations of our algorithm through simulation of handwritten digit recognition with various numbers of training patterns.

• The Journal of Korean Physical Therapy
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• v.24 no.2
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• pp.127-133
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• 2012

Purpose: This study aims to examine the power changes in eletrocenphalogram (EEG) detected from the tibialis anterior muscle, during repetitive contraction exercise in normal female adults. Methods: The subjects of this study were 24 normal adult females, with no musculoskeletal or nervous system disorders. The 24 female subjects were divided into two groups: 12 subjects comprised a voluntary stimulation training group, and the other 12 subjects comprised an electrical stimulation training group. A total of thirty contractions were made repetitively by each woman, with maximal voluntary contraction exercise for six seconds, and a resting time of three seconds. During the experiment, their EEG was measured at eight positions. The eight positions were Fpz, Fz, Cz, CPz, C3, C4, P3, and P4, in accordance with the international 10~20 system. Results: The relative alpha power and beta power showed no statistically significant differences between the two groups. But the relative gamma power of the CPz, C3, C4, P3, and P4 areas showed statistically significant differences between the two groups (p<0.05). The relative theta power of the C4 area showed statistically significant differences between the two groups (p<0.05). Conclusion: Our findings show that tibialis anterior muscle contraction by electrical stimulation and by voluntary repeated contraction differentially affected brain activation. In particular, the CPz, C3, C4, P3 positions of relative gamma power showed brain activation in voluntary contraction. The C4 position of relative theta power showed different brain activation between the two groups.

• Journal of the Korean Society of Physical Medicine
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• v.18 no.3
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• pp.47-53
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• 2023

PURPOSE: A visual feedback method was proposed to induce brain stimulation in a stroke patient, and among them, there was a treatment using a mirror. On the other hand, mirror therapy focuses only on the functional changes in body movements, and analysis of neurophysiological mechanisms of brain activity is lacking. In addition, studies on evaluating the activity and response generated in specific brain regions during visual feedback training using mirrors are insufficient. METHODS: Fifteen healthy adults (male: 10, female: 5, Years: 23.33 ± 1.23), who were right-handed were recruited. By attaching the C3, Cz, and C4 channels in the sensorimotor cortex using an electroencephalogram, training was performed under the conditions without mirror-based visual feedback (No-condition) and with visual feedback (Tasks-condition). At this time, the immediate activity of the mu-rhythm in response to training was separated and evaluated. RESULTS: The tasks-condition of C3, Cz, and C4 channels activated the relative mu-rhythm rather than the no-condition, and all showed significant differences (p < .05). In addition, in all channels at the start time, the tasks-condition was more active than the no-condition (p < .05). The activity of the cortical response was higher in the tasks-condition than in the no-condition (p < .05). CONCLUSION: The mu-rhythm activity can be evaluated objectively when visual feedback using a mirror is applied to healthy subjects, and a basic analysis protocol is proposed.

• Journal of the Korean Society of Radiology
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• v.16 no.1
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• pp.25-34
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• 2022

Brain computed tomography (CT) is useful for brain lesion diagnosis, such as brain hemorrhage, due to non-invasive methodology, 3-dimensional image provision, low radiation dose. However, there has been numerous misdiagnosis owing to a lack of radiologist and heavy workload. Recently, object detection technologies based on artificial intelligence have been developed in order to overcome the limitations of traditional diagnosis. In this study, the applicability of a deep learning-based YOLOv5s model was evaluated for brain hemorrhage detection using brain CT images. Also, the effect of hyperparameters in the trained YOLOv5s model was analyzed. The YOLOv5s model consisted of backbone, neck and output modules. The trained model was able to detect a region of brain hemorrhage and provide the information of the region. The YOLOv5s model was trained with various activation functions, optimizer functions, loss functions and epochs, and the performance of the trained model was evaluated in terms of brain hemorrhage detection accuracy and training time. The results showed that the trained YOLOv5s model is able to provide a bounding box for a region of brain hemorrhage and the accuracy of the corresponding box. The performance of the YOLOv5s model was improved by using the mish activation function, the stochastic gradient descent (SGD) optimizer function and the completed intersection over union (CIoU) loss function. Also, the accuracy and training time of the YOLOv5s model increased with the number of epochs. Therefore, the YOLOv5s model is suitable for brain hemorrhage detection using brain CT images, and the performance of the model can be maximized by using appropriate hyperparameters.

• Therapeutic Science for Rehabilitation
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• v.8 no.4
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• pp.41-51
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• 2019

Objective : The purpose of this study was to investigate the effects of virtual reality-based activities of daily living (ADL) training on ADL and rehabilitative motivation in patients with traumatic brain injury. Methods : This study was performed using a pre-post design with seven traumatically brain injured patients. Subjects were subjected to virtual reality-based ADL training for 30 minutes a day, 2 to 3 times a week for 4 weeks. Evaluation was conducted before and after the intervention using the Korean Modified Barthel Index (K-MBI), Cognitive Functional Independence Measure (C-FIM), and Volitional Questionnaire (VQ). Changes before and after intervention were analyzed by Wilcoxon signed-rank test, and correlations were analyzed using Spearman's coefficient. Results : After intervention, patients with traumatic brain injury showed significant improvements in K-MBI (p<.05). There was no significant change in total C-FIM score and VQ score (p>.05). Total C-FIM score correlated significantly with VQ score (p<.05, r=.755). The social cognition domain of C-FIM had a significant correlation with VQ score (p<.05, r=826). Conclusions : Virtual reality-based ADL training can improve ADL performance, but further research is needed to determine whether improvements in social cognition and rehabilitative motivation are possible.

• Journal of Industrial Convergence
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• v.22 no.9
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• pp.69-80
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• 2024

This study aims to investigate the effects of an 8-week complex attention concentration program on the brain function index and attention concentration in adolescents with ADHD. The subjects of the study were 18 male adolescents from H School located in I City, divided into three groups: 6 participants in the complex attention concentration program group, 6 in the target-related physical activity group, and 6 in the no-treatment control group. Data analysis included calculating means and standard deviations for group comparisons, and two-way (2RM×6RM) ANOVA was conducted to test differences at various measurement points. Post-hoc tests were performed to examine significant interaction effects (p<.05). The results indicated that the integrated attention training program had a more positive effect on brain function sub-indices compared to both the target-related physical activity group and the no-treatment group. Similarly, the program showed a more positive effect on attention levels compared to the other two groups. Based on these results, it can be concluded that the integrated attention training program significantly improves overall brain function in ADHD students and is advantageous due to its ease of participation. It is suggested that this program could be widely used due to these benefits.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.322-331
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• 2013

The purpose of the present study was to develop a convergent education contents for dementia prevention, operating on the web network applying modern information technology(IT). At the preparation stage, local and worldwide literatures related to dementia were analyzed followed by surveying industry demands, based on which the program was designed and developed. In the following enhancement stage, the program was modified as much as possible by advices obtained from experts in various fields. Development results of the present program are summarized as follows. Firstly, 645 intellect development model to prevent dementia was established through peer review and verification of convergent education theories by expert groups. This model was named as "Garisani" meaning "cognition capable of judging objects" in the Korean language. Secondly, 'Find a way' and 'Connect a line' modules were developed in the numeric field as well as 'Identify a letter(I, II)' modules, in the language field for web-based left brain training program. Thirdly, 'Find my car' and 'Vision training' modules in the attention field and 'Object inference' and 'Compare pictures' modules in the cognition field were developed for web-based right brain training program. Fourth, 'Pentomino' and 'BQmaze'(Brain Quotient and maze) modules in the space perception field and 'Visual training' in the memory field were developed for web-based left and right brains training. Fifth, all results were integrated leading to a 52 week Garisani convergent education program for dementia prevention.