• Proceedings of the Plant Resources Society of Korea Conference
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• v.18 no.1
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• pp.130-133
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• 2005

• Proceedings of the Plant Resources Society of Korea Conference
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• v.18 no.1
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• pp.127-129
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• 2005

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.13 no.2
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• pp.182-187
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• 2000

Current status and quality administration of botanical products in America which has one of the biggest market need to be analyzed for the internationalization of oriental medicine. In this study, current status of botanical products as dietary supplements was analyzed and quality adminstration by United States Pharmacopoeia and National Formulary(USP-NF) was compared with The Korea Pharmacopoeia and botanical drug standard collection(KP), Even though the number of botanical products in USP-NF is small, it is rapidly increasing and more detailed compared with KP. Especially, reference standard compound should be determined for each botanical drugs, and more detailed standard for other items should be established in KP considering international trends. Though the history of botanical drugs in America is short, its annual market is about 3.2 billion dollar, so American administration system should be examined carefully for the internationalization of oriental medicine and related industry.

• Journal of Korean Traditional Oncology
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• v.20 no.1
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• pp.11-21
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• 2015

Objectives : The cancer incidence and cancer burden is increasing. In addition, the use of botanical agents in cancer care is increasing. This article aims to review a research strategy for botanical agents. Methods : The clinical studies of anticancer botanical agents and the papers about clinical research methodology of botanical agents were reviewed. Results : In phase I study, safety confirmation, optimal dose determination and drug interaction study are important. Most botanical agents have low toxicity and some have non-monotone dose response. Therefore, dose-response curve must be evaluated separately from the dose-toxicity curve to determine optimal dose. Although anticancer botanical agents can't shrink tumor size rapidly, they do extend survival. So, in phase II study, response should be evaluated by the survival. Conclusions : Clinical research of botanical agents in cancer is different from traditional methods and strategies. Considering the characteristics of botanical agents and experimental mechanism is necessary in conducting botanical based clinical trials.

• BMB Reports
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• v.50 no.3
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• pp.111-116
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• 2017

Natural product drugs, or botanical drugs, are drugs composed of natural substances which have constituents with healthenhancing or medicinal activities. In Korea, government-led projects brought attention to botanical drugs invigorating domestic botanical drug industry. Foreign markets, as well, are growing bigger as the significance of botanical drugs stood out. To follow along with the tendency, Korea puts a lot of effort on developing botanical drugs suitable for global market. However, standards for approving drug sales vary by countries. And also, thorough standardization, certification, clinical studies and data of these will be required as well as data confirming safety and effectiveness. Meanwhile, as an international exchange in botanical drug market continues, the importance of plant resources was emphasized. Thus countries' ownership of domestic natural resources became vital. Not only establishing a systematic method to secure domestic plant resources, but also cooperation with other countries on sharing natural resources is essential to procure natural resources effectively. Korea started to show visible results with botanical drugs, and asthma/COPD treatment made out of speedwell is one example. Sufficient investment and government's active support for basic infrastructure for global botanical drugs will bring Korea to much higher level of botanical drug development.

• Journal of the Korean Institute of Landscape Architecture
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• v.47 no.3
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• pp.49-59
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• 2019

This paper examines the background and content of Thomas Jefferson's botanical garden plan for the University of Virginia. When Jefferson promoted the establishment of a botanical garden, European botanical gardens were evolving from physic gardens, and American botanical gardens were in their infancy. Accordingly, this paper compares the Botanical Garden Plan for the University of Virginia with contemporary botanical gardens. This is examined by outlining the trends of botanical gardens in Europe and the United States around the nineteenth century, analyzing their function and spatial structure. Also, Jefferson's perspective on botany, his plan, and botanical gardens are reviewed. This study found that Jefferson's project had its background in the social recognition of the importance of botany as a practical science, advancing the national economy, which was a prominent goal in late eighteenth-century Europe, and in developing networks of exchanging plants and information concerning botany and botanical gardens. Based on the botanist Correia's opinion on the role of a public botanical garden, the Botanical Garden Plan for the University of Virginia was developed by Jefferson as an action plan, including its site creation, space organization, and supplying of plants. Compared to the other contemporary botanical gardens, the University of Virginia's Botanical Garden Plan has the following characteristics. First, like European gardens in the late eighteenth century, it evolved from being a physic garden to a botanical one. As such, it emphasized botanical research and education over medicine, creating a tree garden and a plant garden. Second, it differed from many European and American botanical gardens in that it rejected decorative elements, refused to install a greenhouse, and attempted to spread practical overseas plants suitable to the local climate. This study contributes to broadening the history of botanical gardens at the turn of the nineteenth century.

• Journal of the Korean Institute of Landscape Architecture
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• v.46 no.1
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• pp.49-60
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• 2018

The role of the botanical garden in securing biodiversity, responding to climate change, and sustainable development in modern cities is becoming more important. Private botanical gardens that lead the domestic botanical culture are declining due to complex reasons such as an increase of tourist destinations, lack of policy support, lack of introduction of advanced management strategies, and similar leisure activities to national and public botanical gardens. The Private Botanical Garden not only has a large number of plant species with high conservation value, but also provides various public utilities as a cultural and educational space and government efforts are needed to activate the operation of this amenity. The purpose of this study is to evaluate the value of public functions provided by private botanical gardens using the Contingent Valuation Method (CVM). In this way, the government aims to provide a basis for policy and institutional support for private botanical gardens. The main results are as follows. First, public utility functions provided by private botanical gardens were recognized as 'preservation' (23.4%), 'recreation and tourism' (17.5%) and 'research' (16.6%) in order of analytic hierarchy process (AHP). Second, 'heritage value' (33.0%) and 'existence value' (32.5%) were recognized as significant among the values provided by private botanical gardens. Third, the willingness to pay (WTP) to preserve the public functions of the private botanical garden was 12,234 won. Based on this, the economic value of all private botanical gardens in the whole country was estimated, resulting in about 233.8 billion won. There is a need to revise laws and regulations related to financial support for the revitalization and quality improvement of private botanical gardens. It is also necessary to establish a cooperative operating system between national, public and private botanical gardens.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.70-70
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• 2019

본 연구는 인천시 강화군 퇴모산(338m) 일원을 중심으로 식물상을 조사하였다. 관속식물은 76과 210속 268종 3아종 27변종 3품종으로 총 301분류군으로 조사되었다. 분류군별로 양치식물이 4과 5분류군, 나자식물 2과 4분류군, 쌍자엽식물이 61과 226분류군, 단자엽식물이 9과 66분류군이 확인되었다. 주요 식물로 특산식물은 할미밀망(Clematis trichotoma), 백운산원추리(Hemerocallis hakuunensis), 늦둥굴레(Polygonatum infundiflorum)로 3분류군, 희귀식물은 관심대상종(Least Concern)인 두루미천남성(Arisaema heterophyllum), 정보부족종(Data Deficient)인 늦둥굴레(Polygonatum infundiflorum)로 2분류군이 확인되었다. 침입 외래식물은 돼지풀(Ambrosia artemisiifolia), 미국자리공(Phytolacca americana), 좀명아주(Chenopodium ficifolium), 달맞이꽃(Oenothera biennis L.), 털별꽃아재비(Galinsoga ciliata (Raf.) S.F.Blake) 등 10과 20분류군이 조사되었다. 유용식물로는 용도를 모르는 49분류군(16.3%)을 제외하면 252분류군(83.7%)이 자원식물로 이용가치가 있는 것으로 나타났다. 이들을 용도에 따라 구분해보면 식용 130분류군(29.4%), 섬유용 3분류군(0.7%), 약용 106분류군(24.0%), 관상용 34분류군(7.7%), 사료용 141분류군(31.9%), 산업용 3분류군(0.7%), 염료용 10분류군(2.3%), 목재용 15분류군(3.4%)으로 조사되었다.

• Natural Product Sciences
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• v.12 no.3
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• pp.162-165
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• 2006

Curcuma aeruginosa Roxb. (FamilyZingeberaceae), commonly known as 'pink and blue giner' is widely used in Indian system of medicine since time immemorial. The plant is found well in wild habitat and cultivated in southern India. The plant is distinguished by red corolla lobes and ferruginous or greenish-blue rhizome. Rhizoma is used medicinally as anti-diarrheal, anti-fungal; external use as astringent for wounds. A detailed pharmacognostic evaluation of its rhizome showed total ash 6.1%, acid insoluble ash 1.20%, alcohol soluble extractives 3.70% , water soluble extractives 14.50%, sugar 20.93%, starch 41.85%, and tannins 0.68%. Oh hydro distillation, the rhizomes and sessile tubers yielded 0.17% oil.

• Natural Product Sciences
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• v.10 no.4
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• pp.177-181
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• 2004

Antidiabetic treatment with tubers of Asparagus racemosus (Liliaceae) extract (l00 and 250 mg/kg body weight) for three weeks showed significant reduction in thiobarbituric acid reactive substances (TBARS) and glutathione reductase (GSH-R) in both liver and kidney. The treatment with A. racemosus significantly altered the glutathione (GSH) and GSH-R to be comparable with the control group. A. racemosus and glibenclamide treated rats showed decreased lipid peroxidation that is associated with increased activity of superoxide dismutase (SOD) and Catalase (CAT). The ability of A. racemosus on tissue lipid per oxidation and antioxidant status in diabetic animals has not been studied before. The result of this study thus shows that though, A. racemosus possesses moderate antidiabetic activity, but it exhibits potent antioxidant potential in diabetic conditions.