• Journal of Nutrition and Health
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• 제31권9호
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• pp.1446-1456
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• 1998

Bones are important parts in sustaining the shape of the body, but they are also metabolic organs which undergo bone remodeling by constant bone resorption and formation. Osteoporosis, the typical metabolic bone disease, is characterized by a reduction in bone mineral density (BMD). Women more than men are at risk fir osteoporosis-related fractures, especially in the lumbar spine, wrist, and hip region. Risk of fracture depends on one's BMD, which open determined by the peak bone mass value achieved at skeletal maturity and followed by subsequent age-and menopause-related bone loss. Genetic and environmental factors are known to play a key role in bone metabolism and diet is considered as one of the important environmental factors. The purpose of the present study was to assess the status of BMD and bone mineral content(BMC) to clarify the relationships between dietary intakes and the risk of osteoporosis in adult women in Taegu. Subjects were 130 healthy females in between 20 and 69 years of age. BMD and BMC of the lumbar spine(venebrae L2-4) of the subjects were measured by dual energy X-ray absorptiometry. The average age of the subjects was 47.4${\pm}$11.7 years old, the average weight was 57.2${\pm}$8.4kg, the average age of menarche was 16.6${\pm}$1.9 years old and the average age of menopause was 48.4${\pm}$5.3 years old. The nutrient intakes of the subjects measured by the convenient method were generally lower than the level of RDA. The result of nutrient intake assessed has shown that the average energy intake was 1701${\pm}$316kca1 which is 85.1% of the RDA and the average calcium intake was 485.4${\pm}$172.3mg which is 69.3% of the RDA. The intakes of protein, vitamin A, vitamin B$_1$, niacin were greater than the RDA, whereas the remaining nutrient intakes were lower than the RDA. The average BMD of the subjects was shown to be 1.06${\pm}$1.09g/$\textrm{cm}^2$. The highest BMD of 1.24${\pm}$0.14g/$\textrm{cm}^2$ was noticed in the subjects of 30s compared to 20s, 40s, 50s, 60s. The BMD values were compared by the relative body weight(R3W) of the menopause subjects, and it was found that the underweight group had significant lower BMB while the rest of the groups did not have any differences in BMD. The most strongly correlated nutrient with BMD among the menopause subjects appeared to be calcium. The women whose Ca intakes were higher than 500mg showed the significantly higher BMD than those with Ca intakes lower than 500mg. This study suggests that the most effective way to prevent osteoporosis and to reduce the incidences of fractures seems to be minimizing bone loss through the adequate intake of calcium as well as avoiding underweight, especially in menopausal women. (Korean J Nutrition 31(9) . 1446-1456, 1998)

• Journal of Periodontal and Implant Science
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• 제28권3호
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• pp.431-451
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• 1998

4 beagle dogs aged over one and half years and weighed 15 to 16 Kg were utilized in this study. Experimental dehiscent defects were made in the mandibular edentulous area after removal of lower premolar. e-PTFE membrane resorbable membrane, and PDGF-BB-loaded resorbable membrane were covered at the dehiscent defects around the dental implants respectively. Animal was sacrificed at 1, 2, 3 months respectively. Non-decalicifed specimens were made and mutiple-stained for light microscopic study. The results were as follows: 1. Dehiscent defects around the implant installed in the beagle dog were an excellent defect model for studying guided bone regeneration. 2. Fibroblasts penetrated into expanded-PTFE membrane was observed and inflammatory cell infiltration was also observed around the membrane. 3. Resorbable membrane was degradaded and resorbed at 1 month after application to the dehiscent defect. Though multinucleated giant cells were observed adjacent to the membrane, that had no reverse effect on the boe regeneration. 4. PDGF-BB-Ioaded resorbable membrane was same capability as the resorbable membrane and e-PTFE membrane in the guided bone regeneration. 5. PDGF-BB-Ioaded resorbable membrane-applied site was better than resorbable membrane-applied site in the speed and maturity of bone formation. Within the above results, it was suggested that PDGF-BB-Ioaded resorbable membrane might have same bone regeneration capacity as nonresorbable membrane in the dehisced implant of the beagle dog and potentiality to use in human subjects.

• 대한한방소아과학회지
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• 제37권3호
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• pp.111-120
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• 2023

Objectives The purpose of this study is to analyze the characteristic of the 157 pediatric patients who visited a Korean medical hospital for bone age (BA) measurement and to compare the BA measurement using Tanner-Whitehouse 3-based analysis software and specialists in pediatric Korean medicine to determine the relationships. Methods The study included 157 pediatric patients who visited a Korean medicine hospital for BA measurements from June 2021 to June 2023. They were analyzed to determine the characteristics and agreement of BA measurements using Tanner-Whitehouse 3-based analysis software and specialists using classification by age, intraclass correlation coefficient (ICC), and Bland-Altman plots. Results In total, 61.8% of the study population were boys and 38.2%, girls, with an average age of 11.32 ± 1.87. The types of growth were various, and the average of bone maturity was 0.48 ± 1.13 as concluded by analysis software and 0.38 ± 1.15 as concluded by the specialists. The ICC of two methods were excellent: 0.995 (overall), 0.996 (boys) and 0.994 (girls). However, BA determined by analysis software tended to be higher than that determined by specialists when the patients were young. Conclusions This study showed that patients visited the hospital for BA measurement regardless of their height, and the agreement of BA between the two methods can be used as a reference. However, there was differences in the trends between age and sex, which should be interpreted with caution.

• 대한치과교정학회지
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• 제28권3호
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• pp.409-417
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• 1998

경희의료원 치과병원 교정과에 내원한 부정교합자 중 전신 건강 상태가 양호한 123명의 좌측 수완부골 방사선 사진을 이용하여, 초경과 골격성숙도간의 상관관계를 연구한 결과 다음과 같은 결론을 얻었다. 1. 초경 발현 연령은 평균 12.31세, 최소 9.6세, 최고 15.6세로 개체간 변이가 심하였다. 2. 초경시 골성숙 상태는 SMI 7,8단계($73\%$), 즉 제5중절골의 골단이 골간을 둘러싸거나 제3말절골의 골간과 골단이 융합되는 단계이며, 초경시의 골격성숙도는 초경 발현 연령에 관계없이 일정하였다. 3. 골성숙단계에 따른 초경 후 경과기간간에는 유의한 차이가 있었다. 4. 요골의 융합은 초경 후 평균 1년 8개월이 지나면 시작되었다. 5.초경 발현 연령에 따른 성장 속도의 비교에서, 만기성숙아(초경을 늦게 경험하는 여아)는 초경 후 14개월이 지나면 요골의 융합이 시작되었고, 조기성숙아(초경을 일찍 경험하는 여아)는 초경후 22개월, 평균성숙아는 초경후 20개월이 지나면 요골의 융합이 시작되었다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제27권4호
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• pp.315-323
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• 2005

For reconstruction of the bony defect, distraction osteogenesis has many advantages in comparison with bone graft. However, it needs long consolidation period for sufficient bone maturity. This study is performed to evaluate the effect of PRP injection into the distracted mandible on bone formation in rabbits. Twelve house rabbits, weighing 2 kg, were used. All animals underwent bilateral mandibular osteotomy under general anesthesia. A internal distractor divice was positioned along a plane perpendicular to the line of osteotomy. After 5 days of latency period, distraction osteogenesis was started at a rate of 1 mm/day for 9 days which was distracted 9 mm totally. After completion of distraction, 0.5 ml of PRP which collected in rabbit blood was injected into the distracted mandible on experimental group, whereas no injection was done in control group. Macroscopical, radiographical, and histological, and histomorphometric examinations were performed 2, 4 and 8 weeks after distraction. All animals showed distracted mandible and severe anterior cross-bite. In radiographical findings 2 weeks after distraction, more radiopacity in the distracted gap was found in experimental group than that of control group. At 4 weeks after distraction, distracted bone was similar to normal bone in experimental group. In histological findings, 1) At 2 weeks after distraction, number of osteoblasts and angiogenesis in the distracted gap was found in experimental group than that of control group. 2) At 4 weeks after distraction, more active and distinct bone in the distracted gap was found in experimental group than that of control groups. 3) At 8 weeks after distraction, more dense and matured lamellated bone in the distracted gap was found in experimental group than that of control group. In histomorphometrical findings 8 weeks after distraction, more bone formation was observed in experimental group than control group (p<0.01). These results indicate that administration of PRP into the distracted mandible can promote bone formation.

• 대한족부족관절학회지
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• 제10권2호
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• pp.242-246
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• 2006

Purpose: Frequency of sesamoid bone on hallucal interphalangeal joint has been described to be low probability in orthopaedic and anatomical literature. We have, however, experienced two cases of interphalangeal joint dislocation giving difficulty to usual manipulative reduction because of presence of sesamoid bone recently. In order to ascertain existence of sesamoid bone on interphalangeal joint of hallux in Korean adults, radiological study have been performed with feet of patients Materials and Methods: Between May 2003 and October 2006, 974 patients with 1098 radiographs of feet which were reached skeletal maturity over 18-year-old were examined. Unilateral or bilateral anteroposterior, lateral and oblique radiographs were observed by one same person and presence was recorded if there was sesamoid in films. Distance of long and short axes were measured in lateral view and cases of two sesamoids in interphalangeal joint were recorded. Statistical differences between left and right side or between men and women were evaluated by chi-square test. Results: Frequency of sesamoid was 980 cases (89.3%) and no occurrence in 118 cases (10.7%). Two sesamoids were observed in 3 cases. Average distance of long axis was 4.9 mm (range, 0.5-11.4) and average distance of short axis was 3.5 mm (range, 0.3-9.3). Unilateral sesamoid was observed in 7 patients (5.6%), bilateral absence was 7 patients (5.6%) and bilateral sesamoids in 110 patients (88.8%) out of 124 patients who took bilateral feet radiographs. Men has less frequency than women significantly (p=0.014) while there was no significant difference in frequency according to side(p>0.05). Conclusion: Sesamoid bone was seen in 980 feet (89.3%) out of 1098 normal Korean radiological studies of feet. We report 3 cases of two seamoids which was extremely rarely reported in literature. Korean frequency is similar with Japanese, but much higher than Caucasians and black Africans.

• 대한소아치과학회지
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• 제21권2호
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• pp.518-524
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• 1994

A traumatically intruded tooth is one that is forcefully and abruptly dispaced from its position into the surrounding alveolar bone. Although intrusion of permanent teeth is infrequent, the sequelae compromise the longevity of the tooth and often include pulp necrosis, internal and external root resorption, rupture of periodontal ligament and loss of marginal bone. The purpose of this study was to examine three common management techniques for traumatic intrusion, observation for re-eruption, surgical repositioning & fixation and orthodontic extrusion. In the recent, the accepted treatment was to allow the permanent teeth to reerupt spontaneously for 6-8 weeks. If this did not occur, orthodontic traction was applied. The pulpal status of the teeth was monitored and either calcium hydroxide therapy or conventional endodontics was instituted following pulpal necrosis depending on the maturity of the root end. Pulpectomy and a calcium hydroxide filling were also the treatment of choice if there was evidence of internal or external root resorption. This will reduce the chance of root resorption and provide a period of monitoring prior to a definitive root canal filling.

• 대한치과교정학회지
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• 제51권3호
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• pp.217-227
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• 2021

Maxillary transverse deficiency often manifests as a posterior crossbite or edge-to-edge bite and anterior crowding. However, arbitrary arch expansion in mature patients has been considered to be challenging due to the possible periodontal adverse effects such as alveolar bone dehiscence and gingival recession. To overcome these limitations, nonsurgical maxillary expansion of the basal bone has been demonstrated in young adults. However, the age range for successful orthopedic expansion has remained a topic of debate, possibly due to the underlying individual variations in suture maturity. This case report illustrates nonsurgical, miniscrew-assisted rapid palatal expansion (MARPE) in a 60-year-old patient with maxillary transverse deficiency accompanied by anterior and posterior crossbites, crowding, and gingival recession. The use of MARPE allowed relief of crowding and correction of the crossbite without causing significant periodontal adverse effects.

• 대한치과교정학회지
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• 제29권2호
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• pp.183-195
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• 1999

성장기 환자의 교정치료에서 신체의 성장 발육상태를 파악하는 것은 중요한 의미를 갖는다. 특히 부정교합에 따라 성장 발육시기가 차이를 보인다면 교정치료 시기의 선택에 있어서 이에 대한 고려가 있어야 하므로 부정교합의 양상에 따른 성장 발육상태를 평가하는 것이 필요할 것이다. 이에 본 연구에서는 부정교합 분류에 따라 골성숙도에 차이가 있는지를 조사하기 위해, 8-10세의 여자 I급 부정교합자 38명, II급 부정교합자 36명, III급 부정교합자 33명을 대상으로 약 6개월 간격으로 12-13세까지 누년적으로 촬영한 수완부골 방사선 사진을 이용하여 골성숙도를 평가한 결과 다음과 같은 결론을 얻었다. 1. 부정교합에 따른 골성숙도의 차이는 없었다. 2. 유구골의 구상돌기 (hamular process)는 $9.16{\pm}0.72$세, 두상골(pisiform bone)은 $9.13{\pm}0.71$세, 모지척측 종자골(ulnar sesamoid)은 $10.34{\pm}0.84$세에 관찰되었다. 3. 골단이 골간을 둘러싸는 시기는 셋째 수지의 원심부 지절과 중간 지절에서 각각 $10.96{\pm}0.80$세, $11.27{\pm}0.87$세였으며, 첫째 수지의 근심부 지절에서는 $11.12{\pm}0.86$세, 요골에서는 $11.21{\pm}0.82$세, 다섯째 수지의 중간 지절에서는 $11.62{\pm}0.85$세였다. 4. 두상골의 출현은 유구골 구상돌기의 출현과(r=0.91), 모지척측 종자골의 출현은 구상돌기의 진행성 화골시기와 높은 상관관계를 보였으며(r=0.86), 골단이 골간을 둘러싸는 시기는 여러 부위가 상호간에 높은 상관관계를 나타내었다(r=0.80-0.90). 5. 다섯째 수지의 중간 지절의 형태가 가장 변이가 심하였다($20.6\%$).

• 대한소아치과학회지
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• 제39권4호
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• pp.357-365
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• 2012

교정치료에는 치아를 움직이는 치열교정치료와 골격적인 이동을 도모하는 악정형 치료가 있다. 소아청소년기 아동에서 특히 악정형 치료를 위해서는 골 성숙도와 성장 잠재력의 평가가 매우 중요하다. 본 연구의 목적은 6~13세 정상 교합 아동을 대상으로 측모 두부 규격 방사선사진과 수완부골 방사선사진을 촬영하여 발달 단계를 평가하고 하악골 성장량을 비교한 것으로 다음과 같은 연구결과를 얻었다. SMI와 CVM은 유의한 상관관계를 나타냈다(p < 0.05). 수완부골 성숙도가 증가할수록 Ar-Go, Co-Go, N-Go, S-Gn, N-Me, Co-Gn, Go-Me, Go-Gn이 증가하였고, 경추골 성숙도가 증가할수록 Ar-Go, Co-Go, N-Go, S-Gn, N-Me, Co-Gn, Go-Me, Go-Gn이 증가하였다. 또한 Ar-Go, Co-Go, N-Go, S-Gn, N-Me, Co-Gn, Go-Me, Go-Gn은 경추 및 수완부골 성숙도와 각각 유의한 상관성을 보였다(p < 0.05). 이상의 결과로 하악골 성장은 경추 및 수완부골 성숙도와 유의한 상관성이 있음을 알게 되었다.