• Journal of Korean Academy of Nursing
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• v.34 no.5
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• pp.760-770
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• 2004

Purpose: This study was done to identify the effects of weight-bearing exercise(WBE) on bone metabolism. Method: WBE was performed for 12 weeks by healthy college women. Bone-related parameters were measured four times during this period by evaluating the immunoradiometric assay and enzyme immunoassay. Bone mineral densities(BMDs) were measured by dual energy x-ray absorptiometry before and after the WBE program. Data was analyzed using t-test, paired t-test, $x^2$-test, and repeated measures ANOVA. Result: Osteocalcin, a bone formation marker, increased more in the experimental group than in the control group based on the interaction between time and group(F=3.29 p=.024). Little difference between the two groups was found for the other parameters: urinary deoxypyridinoline, insulin-like growth factorI, parathormone, serum calcium, and serum phosphorus without showing any time interaction between the groups. The femoral trochanter BMD rose in the experimental group while that of the control group fell, showing a significant difference for BMD(t=3.06 p=.005). However, there was no significant difference between the two groups for changes in BMD of the forearm, lumbar spine, femoral neck, and femoral ward's triangle. Conclusion: These findings supported the WBE is beneficial for increasing bone formation in college women and long-term application is needed to substantiate the effects of WBE as a intervention in promotion of bone-health.

• PNF and Movement
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• v.11 no.2
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• pp.127-134
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• 2013

Purpose : The purpose of this study of normal elderly and stroke patients by comparing the dominant side and recessive side was to evaluate the differents between each Methods : Thirty-two elderly participated in this study. They were classified two groups: stroke patients group and the normal elderly group. Outcome measures were: general characteristics and BMD. General characteristics included age, height, weight and body mass index. BMD was represented in the osteoporosis index, T-score and Z-score. The measurements of bone mineral density were evaluated on the calcaneus region of the dominant and recessive side, using OsteoPro. The data analyzed using SPSS 17.0 software and the Paired-sample T-test and the Independent-sample T-test Results : OI, T-score, Z-score showed no significant differences between dominant side and recessive side in normal elderly group. But stroke patients group showed OI, T-score, Z-score significant differences between paretic side and nonparetic side. Change score subtracted recessive side from dominant side was significant differences between stroke patients group and normal elderly group. Conclusion : There is positive relationship between physical activity and BMD in stroke patients. Therefore, improved physical activity can have a beneficial effect by reducing osteoporosis in stroke patients, considering a positive relationship between physical activity and BMD.

• Imaging Science in Dentistry
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• v.38 no.1
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• pp.1-5
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• 2008

Purpose: The primary aims of this retrospective study were to compare subjective bone quality and bone quality based on the Hounsfield scale in different segments of the edentulous jaw, and to establish quantitative and objective assessment of the bone quality. Materials and Methods: Twenty eight randomly selected cone-beam computed tomographic (CBCT) scans were analyzed. For evaluation one hundred and twelve edentulous areas were selected. Implant recipient sites were evaluated visually for Lekholm and Zarb classification. The same sites were subsequently evaluated digitally using the Hounsfield scale with Vimplant$2.0^{TM}$, and the results were correlated with visual classification. Data was subject for statistical analysis in order to determine correlation between recorded HU and the regions of the mouth with the Kruskal-Wallis test. Results: The highest unit/mean density value (311 HU) was found in the anterior mandible, followed by 259 HU for the posterior mandible, 216 HU for the anterior maxilla, and 127 HU for the posterior maxilla. These results demonstrate a strong correlation for HU depending on the region of the mouth (p<0.001). The relationship between HU and type 4 bone was found to be significant (r=0.74). Conclusion: Knowledge of the Hounsfield value as a quantitative measurement of bone density can be helpful as a diagnostic tool by using $CBMercuRa6^{TM}$ with $Vimplant^{TM}$ software.

• Journal of Mechanical Science and Technology
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• v.15 no.7
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• pp.1022-1031
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• 2001

The elastic modulus and fatigue properties of canine and human trabecular bone tissues (single trabecular) were experimentally determined on a microstructural level using four-point bending cyclic test, and they were compared based on microstructural characteristics and mineral density. The results showed that canine trabecular bone tissue had significantly lower modulus and lower fatigue strength than human tissue. The observed microstructural differences between the two tissues may be more responsible for the differences, although the lower mineral density in canine tissue might also have contributed to the lower modulus and fatigue strength.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.518-521
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• 2005

We performed the mechanical test for obtaining properties of femoral head. Tested sample was male and 35 years old. We measured bone mineral density by dual X-ray absorption method(DEXA). Results of DEXA, he has normal condition of bone density. His BMD $1.159g/cm^2$ and T-Score is 1.6. Tested femurs were harvested by surgical method from donated cadaver. We made 9 specimens in femoral head, 8 specimens in neck used by diamond core drill. Then we performed compressive test in saline solution at $38^{\circ}C$. We obtained results that elastic modulus of femoral head was 0.439GPa, neck was 0.459GPa. Compressive strength of femoral head was 7.441 MPa, neck was 7.095MPa. There was no significant difference of mechanical properties between left and right femoral head & neck. Invested local properties of femoral head have more strength superior and anterior side, femoral neck has more strength in superior and inferior side but other side except for superior has more weakness along the lateral side.

• The Journal of Korean Academy of Prosthodontics
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• v.38 no.3
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• pp.291-309
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• 2000

Statement of problem. There were several studies on the effects of irradiation to peri-implant bone tissue. However, no clear biological effect of irradiation on peri-implant bone tissue was reported yet. Purpose. This study compared the effect of irradiation on the surrounding tissue of a HA-coated implant fixture with controls. Material and methods. 6 Steri-Oss implants were implanted into the femur of 6 mongrels. The implanted dogs were divided into three groups and received irradiation. After 1 month, 2months and 4 months healing period, the histologic examination and mobility test and digital radiographic imaging analyses were performed to compare the control and experimental group respectively. Results. The irradiated group showed slower healing than control group in light microscopic observations. The mobility test demonstrated significant less number (Periotest) in control group than that of irradiated groups. The digital radiographic imaging analysis showed that the bone density of irradiated group was higher than control group. Conclusion. Generally, control group showed favorable biological response and less mobility than irradiated group. The conflict result of bone density value were measured by the digital radiographic imaging analysis. The digital radiographic imaging analysis needs more research in future.

• The Journal of Advanced Prosthodontics
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• v.14 no.3
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• pp.143-149
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• 2022

PURPOSE. Masticatory loading triggers active bone remodeling, altering alveolar bone mineral density (BMD). While dental implants are placed to bear masticatory loading, their influence on changing bone properties has not been fully investigated. Objective of this pilot study was to examine whether the dental implantation has an effect on BMD distribution of bone by comparing dentate, edentulous, and edentulous patients with implants. MATERIALS AND METHODS. Cone beam computed tomography (CBCT) images of 19 partially edentulous patients (Dent), 19 edentulous patients (Edent), and 16 edentulous patients who received implants in the mandible (Edent+Im), were obtained. CBCT images were also obtained from 5 patients within Edent+Im group, before implant placement and after implant loading. Basal cortical bone region of the mandible was digitally isolated. A histogram of gray levels proportional to BMD was obtained to assess mean, histogram standard deviation (HSD), fifth percentile of low and high values (Low₅ and High₅) of the BMD distribution. Multivariate analysis of variance and paired t-test were used to compare the BMD parameters among the 3 dental status groups and between pre- and post-implantation, respectively. RESULTS. Edentulous patients with implants had significantly greater HSD and High₅ values compared to edentulous patients (P < .013). All other comparisons were not significant (P > .097). Mean, HSD, and High₅ values significantly increased after receiving implants (P < .022). CONCLUSION. The current findings suggested that receiving dental implants promoted oral bone mineralization for edentulous patients. The longitudinal investigation could provide valuable information on understanding the effects of implantation on the behavior of oral bone quality.

• Korean Journal of Exercise Nutrition
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• v.23 no.4
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• pp.36-42
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• 2019

[Purpose] The study aimed to determine the effects of bone-specific physical activity on body composition, bone mineral density (BMD), and health-related physical fitness in middle-aged women. [Methods] One hundred eighty-six middle-aged women aged 31-49 years participated in this study. The subjects were divided into tertile groups according to the level of physical activity (low-score group, n=62; middle-score group, n=62; high-score group, n=62). Bone-specific physical activity participation was assessed using the bone-specific physical activity questionnaire. Body composition and BMD were measured using dual-energy X-ray absorptiometry. Health-related physical fitness test included isometric muscle strength (grip strength), muscular endurance (sit-ups), flexibility (sit and reach), and cardiorespiratory fitness (maximal oxygen uptake [VO_2max]). [Results] The high-score group had a significantly higher fat-free mass (p=.045, partial eta-squared value[η_p²]=.033) than the middle- and low-score groups, whereas the high-score group had significantly lower percent body fat (p=.005, η_p²=.056) than the other two groups. Whole-body BMD (p=.034, η_p²=.036) and lumbar BMD (p=.003, η_p²=.060) were significantly higher in the high-score group than in the low-score group. The high-score group performed significantly better for grip strength (p=.0001, η_p²=.101), sit-ups (p=.0001, η_p²=.108), and VO_2max (p=.0001, η_p²=.092) than the other two groups. [Conclusion] The present study suggests that bone-specific physical activity could be useful in improving body composition, BMD, and health-related physical fitness in middle-aged women, significantly enhancing their BMD and health conditions.

• Nutrition Research and Practice
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• v.8 no.5
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• pp.539-543
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• 2014

BACKGROUND/OBJECTIVES: Soy isoflavones are structurally similar to estrogen and bind to estrogen receptors, suggesting that they exhibit estrogenic activities; therefore, they are referred to as phytoestrogens. Fermentation may affect the bioavailability of isoflavones altering soy isoflavone glycosides in the form of aglycones. Thus, this study investigated the effects of fermented soybeans by Rhizopus oligosporus on bone metabolism in both young rats as a pilot test and in ovariectomized (ovx) old rats as a model of menopause. MATERIALS/METHODS: In the pilot test, a total of 24 seven-week-old female Sprague-Dawley (SD) rats were fed one of three diets for a period of four weeks: casein, unfermented soybean product, or fermented soybean product by R. oligosporus. In the ovx rat model, 20-week-old SD rats weighing 260-290 g underwent either sham-operation (n = 10) or bilateral ovariectomy (n = 30) and were then fed the AIN-93M diet for one week. Thereafter, rats were fed sham-casein, ovx-casein, ovx-soybean, or ovx-fermented soybean diet for five weeks. After decapitation, femoral bones were isolated and preserved in 9% formalin for assessment of bone mineral density (BMD), bone mineral content (BMC), and bone-breaking strength (BBS). RESULTS: Ovx rats showed significantly increased weight gain and decreased uterine wet weight. Of particular interest, ovx rats fed fermented soybeans showed increased uterine wet weights compared to control rats. Fermented soybean diet caused a significant increase in plasma 17-${\beta}$ estradiol concentrations in young rats, and 17-${\beta}$ estradiol levels were enhanced in ovx rats to match those of sham-operated ones. Significantly lower femoral BMD and BMC were observed in ovx rats compared to sham-operated controls, whereas bone areas did not differ statistically among the groups. In addition, BBS tended to be increased in ovx rats fed soybeans and fermented soybeans. CONCLUSIONS: Supplementation of fermented soybeans could have preventive and therapeutic effects against osteoporosis in postmenopausal women.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.12 no.1
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• pp.1-9
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• 2018

This study is intended to identify how horseback riding affect the bone density of the elderly. A total of 31 normal senior citizens participated in the research, who were randomly divided into two groups: 15 in horseback riding exercise group and 16 in horseback riding machine exercise group. A horseback riding exercise program was carried out for 25 minutes twice a week for 12 weeks. A pre-test was conducted before starting the program and two post-tests were conducted 6 weeks and 12 weeks after exercises in the same way as the pre-test. Measured items were bone density of lumbar vertebrae and femur. In order to identify the changes in measurement variables before exercises and 6 weeks and 12 weeks after exercises, two-way repeated analysis of variance were used. The comparison of changes in the bone density in both groups revealed that there were significant differences in lumbar vertebrae L3, L4, femur trochanter in both groups over time. This study suggests that three-dimensional movements of horses through horseback riding exercises induce normal movements of senior citizens, providing positive effects on their bone density. If appropriate horse riding exercise programs are used considering the health status, time and economic conditions, and preferences of senior citizens, it would improve their quality of life.