• Journal of Korean Neurosurgical Society
• /
• v.63 no.2
• /
• pp.137-152
• /
• 2020

In spite of the developing endovascular era, large (15-25 mm) and giant (>25 mm) wide-neck cerebral aneurysms remained technically challenging. Intracranial flow-diverting stents (FDS) were developed to address these challenges by targeting aneurysm hemodynamics to promote aneurysm occlusion. In 2011, the first FDS approved for use in the United States market. Shortly thereafter, the Pipeline of Uncoilable or Failed Aneurysms (PUFS) study was published demonstrating high efficacy and a similar complication profile to other intracranial stents. The initial FDA instructions for use (IFU) limited its use to patients 22 years old or older with wide-necked large or giant aneurysms of the internal carotid artery (ICA) from the petrous segment to superior hypophyseal artery/ophthalmic segment. Expanded IFU was tested in the Prospective Study on Embolization of Intracranial Aneurysms with PipelineTM Embolization Device (PREMIER) trial. With further post-approval clinical data, the United States FDA expanded the IFU to include patients with small or medium, wide-necked saccular or fusiform aneurysms from the petrous ICA to the ICA terminus. However, IFU is more restrictive in South Korea than in United States. Several systematic reviews and meta-analyses have sought to evaluate the overall efficacy of FDS for the treatment of cerebral aneurysms and consistently identify FDS as an effective technique for the treatment of aneurysms broadly with complication rates similar to other traditional techniques. A growing body of literature has demonstrated high efficacy of FDS for small aneurysms; distal artery aneurysms; non-saccular aneurysms posterior circulation aneurysms and complication rates similar to traditional techniques. In the short interval since the Pipeline Embolization Device was first introduced, FDS has been firmly entrenched as a powerful tool in the endovascular armamentarium. As new FDS are developed, established FDS are refined, and delivery systems are improved the uses for FDS will only expand further. Researchers continue to work to optimize the mechanical characteristics of the FDS themselves, aiming to optimize deploy ability and efficacy. With expanded use for small to medium aneurysms and posterior circulation aneurysms, FDS technology is firmly entrenched as a powerful tool to treat challenging aneurysms, both primarily and as an adjunct to coil embolization. With the aforementioned advances, the ease of FDS deployment will improve and complication rates will be further minimized. This will only further establish FDS deployment as a key strategy in the treatment of cerebral aneurysms.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.52 no.11
• /
• pp.105-114
• /
• 2015

This paper proposes methods to remove background area and segment region of interest (ROI) in chest X-ray images. Conventional algorithms to improve detail or contrast of images normally utilize brightness and frequency information. If we apply such algorithms to the entire images, we cannot obtain reliable visual quality due to unnecessary information such as background area. So, we propose two effective algorithms to remove background and segment ROI from the input X-ray images. First, the background removal algorithm analyzes the histogram distribution of the input X-ray image. Next, the initial background is estimated by a proper thresholding on histogram domain, and it is removed. Finally, the body contour or background area is refined by using a popular guided filter. On the other hand, the ROI, i.e., lung segmentation algorithm first determines an initial bounding box using the lung's inherent location information. Next, the main intensity value of the lung is computed by vertical cumulative sum within the initial bounding box. Then, probable outliers are removed by using a specific labeling and the pre-determined background information. Finally, a bounding box including lung is obtained. Simulation results show that the proposed background removal and ROI segmentation algorithms outperform the previous works.

• Investigative Magnetic Resonance Imaging
• /
• v.2 no.1
• /
• pp.96-103
• /
• 1998

Purpose : To assess the clinical utility of turbo contrast-enhanced magnetic resonance angiography(CE MRA) in the evaluation of the aortic arch and its major branches and to compare the image quality of CE MRA among different coils used. Materials and Methods : Turbo three-phase dynamic CE MRA encompassing aortic arch and its major branches was prospectively performed after manual bolus IV injection of contrast material in 29 patients with suspected cerebrovascular diseases at 1.0T MR unit. the raw data were obtained with 3-D FISH sequence (TR 5.4ms, TE 2.3ms, flip angle 30, slab thickness 80nm, effective slice thickness 4.0mm, matrix size $100{\times}256$, FOV 280mm). Total data acquisition time was 4. to 60 seconds. We subjectively evaluated the imge quality with three-rating scheme : "good" for unequivocal normal finding, "fair" for relatively satisfactory quality to diagnose 'normal' despite intravascular low signal, and "poor" for equivocal diagnosis or non-visualization of the origin or segment of the vessels due to low signal or artifacts which needs catheter angiography. At the level of the carotid bifurcation, it was compared with conventional 2D-TOF MRA image. Overall image quality was also compared visually and quantitatively by measuring signal-to-noise ratios (SNRs) of the ascending aorta, the innominate artery and both common carotid arteries among the three different coils used(CP body array(n=12), CP neck array(n=9), and head-and-neck(n=8). Results : Demonstration of the aortic arch and its major branches was rated as "good" in 55% (16/29) and "fair" in 34%(10/29). At the level of the carotid bifurcation, image quality of turbo CE MRA was same as or better than conventional 2D-TOF MRA in 65% (17/26). Overall image quality and SNR were significantlygreater with CP body array coil than with CP neck array or head-and-neck coil. Conclusions : Turbo CE MRA can be used as a screening exam in the evaluation of the major branches of the aortic arch from their origin to the skull base. Overall imagequality appears to be better with CP body array coil than with CP neck array coil or head-and-neck coil.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2004.11a
• /
• pp.153-158
• /
• 2004

The numerous investments have been introduced to design and assess mixing zone characteristics of wastewater discharges to the ocean. Specially It strive to meet water quality standard for persistent and bio-accumulative chemical contaminants at the point of discharge through continual improvement pollution prevention measures and other voluntary measures in the developed country. The goals that of this paper are to emphasize the regulatory mixing zone is defined as an allocated impact zone where the numeric water quality criteria may be exceeded as long as acutely toxic conditions are prevent. Furthermore, mixing zones be limited to an area or volume as small as practicable that with not interfere with the designated uses or the established community of aquatic life in the segment for which the uses are designated and the shape be a simple configuration that is easy to locate in the body of water and avoids impingement on biologically important areas and the shore hugging plumes should be avoided This results should be used with caution in evaluation the mixing zone characteristics of a discharge and only in conjunction with information from the effective marine outfall design as well as for the sound harbour design. Thus the numerical investigation using CORMIX has been performed to show the regulatory mixing zone in the near and far field of the marine outfall.

• Proceedings of the ESK Conference
• /
• 1992.10a
• /
• pp.63-67
• /
• 1992

인간이 역사를 이루며 살아오면서 피복은 인간의 생활 수단으로서 빠뜨릴 수 없는 존재가 되었다. 사외 생활을 하면서 인간은 자신을 보호하고 남에게 자신의 이미지를 전달하고 자신의 욕구를 표출하면서 만족시키는데 있어 의복은 가장 중요한 역활을 하고 있고 인간 역시 그러한 것들을 의복에 의존하고 있는 것이다. 그러나 정상인을 위한 의복만 취급되어지는 시장에서 신체장애자들은 정상인보다도 더 세심하게 기능들이 고려된 의복이 필요함에도 불구하고 의복의 기능들을 생각하면서 의복을 선택할 수가 없다. 이러한 사앙들이 대두되면서 현대에 들어 신체 장애자 의복에 있어서 불편함을 없애고 보다 적합한 의복을 만들기 위한 연구가 진행되었다. 신체 장애자의 의복 연구는 Ward가 이 부분에 관심을 표명한 이후 임상 의사들에 의해 연구가 이루어지기 시작했다. 우리나라에서도 1976년 심성식의 한국 신체 장애자의 의복에 관한 연구를 기점으로 이 분야의 관심도가 높아지고 있으나 아직까지는 전반적으로 부족한 실정이다. 특히 위생적인 분야에서는 자료가 매우 부족하다. 이에 본 연구에서는 휠체어를 사용하는 하지 마비자의 체표 면을 떠서 기성복 패턴과 비교를 통해 보다 편안한 바지 패턴을 제시하고, 여름철에 많이 사용하는 직물로 바지를 제작하고 착용시킨후 인체 생리 반응을 분석하여 여름철에 쾌적한 바지를 알아 보았다. 이 연구를 통해 일반인과는 생활 자세가 다른 휠체어를 사용하는 하지 마비자와 일반인이 입는 기성복 바지를 착용 했을 때 생기는 불합리한 요소들을 고려하여 미적이고 기능적 및 위생적인 측면에서 신체 장애자에게 보다 적합한 바지를 제작하기 위한 기초 자료를 제공하고자 한다.값은 $f^{m}$ (p-1)-1 이다. (n=2m)이 많고 흡연 등의 만성 자극 요인이 있으며 술후 음성 호전에 걸리는 기간이 길어 보다 복합적인 측면에서 치료에 임하여야 할 것으로 사료된다. with such configuration.trap with 2.88[eV] deep of injected space charge from the chathode in the crystaline regions. The origin of ${\alpha}$$_2$ peak was regarded as the detrapping process of ions trapped with 0.9[eV] deep originated from impurity-ion remained in the specimen during production process of the material, in the crystalline regions. The origin of ${\beta}$ peak was concluded to be due to the depolarization process of "C=0"dipole with the activation energy of 0.75[eV] in the amorphous regions. The origin of ${\gamma}$ peak was responsible to the process combined with the depolarization of "CH$_3$", chain segment, with the activation

• Korean Journal of Applied Biomechanics
• /
• v.18 no.1
• /
• pp.97-105
• /
• 2008

The kinematic variables for swimming and fin-swimming start motions were analyzed and compared using 3-dimensional cinematography. For the swimming start, the arm segment moved towards the upper rear and trunk towards the upper front followed by a descent towards the lower front, while the fin-swimming start motion showed movement towards the lower front for all segments. The total body center of gravity for the swimming start showed horizontal movement far to the front followed by a rapid descent while the fin-swimming start showed close movement towards the lower front in a short period of time. Upon entering the water, the center of gravity for swimming showed high vertical velocities while fin swimming had high horizontal velocities. For both swimming and fin swimming, the upper extremity velocity had more influence on the total center of gravity velocity than the lower extremities. Flexion of the hip joint was observed before the jump for the fin swimming start while the swimming start showed two flexions in mid-air succeeding the jump. The flexion and extension movements at the knee joint during the fin-swimming start motion were shown to be larger and more rapid than those of fin-swimming.

• The Plant Pathology Journal
• /
• v.22 no.1
• /
• pp.68-74
• /
• 2006

A new virus with a dsRNA genome was isolated and characterized from the Suhan-:neutari strain (ASI 2504) of Pleurotus ostreatus, which was characterized as long and slightly bent with small caps on the stipe of fruit body. Thirty nm isometric viruses with three dsRNA segments (approximately 2.0, 1.84 and 1.82 kb in sizes) were isolated by ultracentrifugation in sucrose gradients. Western analysis of protein extracted purified viruses with anti-virus polyclonal antibody confirmed that viruses have two specific proteins (36 and 68 kDa). Computer analysis of 2.0 kb segment shows that high. sequence identity with RNA-dependent RNA polymerase (RdRp) of partitiviruses, respectively. When compared to other dsRNA mycoviruses in a phylogenetic analysis, OMDV was most related to Pleurotus ostreatus virus 1.

• Korean Journal of Applied Biomechanics
• /
• v.22 no.3
• /
• pp.269-276
• /
• 2012

The purpose of This study's aim is to examine the difference in the changes of body segment movement, variables for ball quality, and carry at golf driver swing according to the ball quality using comparative analysis. Regarding the impact variables according to the ball quality using the track man and carry, club speed was the fastest at draw shot, ball speed was the fastest at straight shot, and smash factor was the lowest at draw shot. About the vertical launch angle, the fade shot showed the highest launch angle while the max height of the ground and ball was the highest at fade shot. And carry was the longest at draw shot. For the flight time, it was the longest at draw shot. The landing angle was the largest at fade shot. About the club head position change and trajectory, at the overall event point, the fade shot drew a more outer trajectory at the point of the follow through(E6) than the straight or draw shot. Regarding the angular speed of shoulder rotation, at the overall event point, the fade shot showed the greatest angular speed change in the follow through(E6). Also, about the angular speed of pelvic rotation, at the overall event point, the draw shot showed the greatest angular speed change at the point of down swing(E4). Concerning the stance angle change, both straight and fade shots were open as the concept of open stance whereas the draw shot was close as that of close stance. Regarding the previous study, the most important factor of deciding Ball Quality is the club face angle's open and close state at Impact. In short, the Ball Quality and carry were decided by this factor.

• The Research Journal of the Costume Culture
• /
• v.19 no.3
• /
• pp.637-649
• /
• 2011

Environmental protection has become more important than ever because of increasing environmental pollution and abnormal climatic changes caused by the depletion of resources from industrial activities. Fashion products can create various environmental pollutants during the production process. Since they are in direct contact with the body, the environment-friendly features for the fashion industry will become increasingly important and the necessity to execute a detailed study regarding the environment-friendly fashion marketing will also become increasingly important. The purpose of this study was to segment the levels of environment-friendly fashion marketing mixes, that analyze the relationship between consumer decision-making factors and purchasing intentions. We propose effective several marketing strategies. A total of 457 questionnaires were analyzed using frequency analysis, t-tests, correlation analysis, regression analysis, and ANOVA in SPSS. The results are as follows: First, environment-friendly fashion products were segmented into four groups, environment-friendly materials, environment-friendly production, environment-friendly management, and recycling/ disuse of products. Second, the promotion of environment-friendly fashion products were highly ranked, followed by materials used, distribution methods, and production management. Third, women considered usage, management, and price for environment-friendly fashion products as more important than men did. Finally, a total of 39.4% of the respondents had purchased environment-friendly fashion products, with a preference to buy environment-friendly underwear, outerwear, bags, shoes, and accessories. By establishing and executing the environment-friendly fashion marketing mixes, fashion companies execute successful marketing activities in both domestic and international markets.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.33 no.2
• /
• pp.120-127
• /
• 2011

Purpose: This study was designed to examine whether the use of neuromuscular electrical stimulation (NMES) after mandibular distraction osteogenesis accelerated bone formation and consolidation. Methods: Eight adult dogs underwent mandibular left body osteotomy. After a 3 day latency period, a distraction rod device was activated at a rate of 1.0 mm once per day for 10 days. After the completion of mandibular lengthening, NMES group was treated twice daily with 2 hours of NMES for 14, and 28 days, while non-NMES group did not receive NMES. The distracted segment was evaluated radiolgraphically histologically and than immunohistochemically for osteopontin (OPN) to evaluate new bone formation and consolidation. Results: Radiography, did not demonstrate significantly different images between the group and the NMES group. Histological examination however, showed that the new bone formation 14 and 28 days after distraction was better in the NMES group when compared to non-NMES group. Immunohistochemical analysis demonstrated that the staining intensity of OPN increased more in the NMES group than in non-NMES group during early consolidation. Conclusion: The results of this study demonstrated that the use of NMES can promote bone formation and consolidation.