• 한국의류학회지
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• 제32권12호
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• pp.1825-1836
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• 2008

3차원 인체 형상에 적합한 의복 패턴을 제작하기 위하여 인체 형상을 평면전개하여 체표패턴을 얻기 위한 다양한 연구들이 진행되고 있다. 본 연구는 Grid method를 이용한 여성 상반신 앞면의 평면전개를 위하여 최적 그리드 기준을 결정하는 것을 목적으로 하였다. Grid method는 인체 형상의 표면에 커브를 생성하고 각 커브의 길이를 플로팅하는 원리에 의하여 3차원 형상을 평면전개 방법이다. 첫째, Young 모델과 Adult 모델에 해당하는 두 개의 3차원 바디들을 사이즈코리아데이타에 기초하여 모델링하였다. 둘째, 각각의 모델을 3차원 특징점에 의하여 shell과 block으로 세분화하였다. 셋째, 각각의 block은 다양한 그리드수의 조합에 의하여 평면전개되었다. 마지막으로, 가장 효율적인 조합을 선정하여 평면전개의 기준으로 제시하였다.

• Archives of Plastic Surgery
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• 제35권5호
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• pp.597-602
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• 2008

Purpose: Presently, silicone rubber is chosen most frequently for nasal augmentation. However, there is a possibility of extrusion with this material. Sometimes, noses are prone to be traumatized, and then silicone rubber has a possibility of deformity or deviation resulting in trauma. We experienced cases with complications and traumatic deformities after the augmentation rhinoplasty. Methods: A retrospective review was performed to determine the characteristics of the implanted nasal silicone prosthesis after trauma. The patients' data such as deviation of implant, shape of fracture, age and sex of the patient, time of treatment, operative methods were reviewed. From March 2001 to March 2008, this study was performed in 30 patients. The patients were 25 females and 5 males, from 24 to 60 years of age, with an average of 42. All patients had previous augmentation rhinoplasty with silicone implant. Results: All of the 30 patients were confirmed as deviation of silicone and nasal bone fractures in the facial bone CT scan. The most common cause of fracture was traffic accident. The classification of nasal trauma after augmentation was done by facial bone CT. Class I: Deviation of silicone without nasal bone fracture without extrusion(12 cases, 40%), Class II: Deviation of silicone without nasal bone fracture and with extrusion(4 cases, 13%), Class III: Deviation of silicone with nasal bone fracture and without extrusion(8 cases, 27%), Class IV: Deviation of silicone with nasal bone fracture and with extrusion(3 cases, 10%), Class V: Mild deviation of silicone with nasal bone fracture(3cases, 3%). Specially, the comminuted or trapezoid nasal fracture was confirmed in 11 cases(Class III, IV). Conclusion: The problems of silicone implant have generally been related to foreign body reactions, rigidity of the material, encapsulation, infections, and extrusion. We experienced 11 cases of comminuted or comminuted trapezoid shaped fracture below nasal implant. So, we think this phenomenon could be used in late problem of silicone implant.

• 한국임상수의학회지
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• 제11권2호
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• pp.529-537
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• 1994

Sector scanner which has a conical end is used to image through the intercostal space because heart is protected by the ribs. Cardiac data published all around the world were also obtained by sector scanner. Although scanners being used in every small animal practice and animal hospital at college in Korea include convex ape and linear type, linear type is not appropriate f3r cardiac scan because of a wide contact surface. The purpose of this study is to establish ultrasonographic images of normal cardiac structures by measuring shape, size of reflectable cardiac structure according to restraint position in scanning normal heart of the puppies with 6.5 MHz convex scanner(SonoAce 4500, Medison, Korea) used in our veterinary teaching hospital, Seoul national university. Seventeen male and female puppies considered having healthy hear by X-ray and clinical examination are used feom April to July 1994. Scanning point selection of probe head and the distinction of imaged cardiac structures were accomplished by necropsy and cardiac scanning performed through thoracotomy under general anesthesia. At 10 o'clock position of transducer(at an angle of 30$^{\circ}$ between imaginary line from elbow joint to 3rd sternum and probe head, 60$^{\circ}$ from body surface, 4th intercostal space of right thorax) with the marker of scanner toward the head of dogs right atrium, left atrium and left ventricle were observed in 2, 3, 4, 5 intercostal space(2cm from the sternum) of experimental dog positioned ventrodorsally under general anesthesia. Under these conditions, the numerical values of imaged diastolic hear are as follows : the distance from skin to apex(mean$\pm$S.D) 47.53$\pm$6.94mm, thickness of left ventricular wall 6.00$\pm$1.60mm, length of left ventricle 16.27$\pm$5.31mm, width of left ventricle 15,33$\pm$4.25mm, length of left atrium 12.33$\pm$3.82mm, width of left atrium 11. 33$\pm$3.94mm, length of right atrium 1.00$\pm$2.41mm, width of right atrium 11.21$\pm$2.76mm and the area of left ventricle 270.92$\pm$109.81mm$^2$, area of left atrium 98.00$\pm$41.08mm$^2$, area of right atrium 62.75$\pm$21.04mm$^2$.

• Archives of Plastic Surgery
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• 제32권1호
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• pp.85-92
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• 2005

Botulinum toxin type A is widely used for anti-wrinkling therapy, and correction of the square face. The toxin ultimately prevent the release of membrane-bound acetylcholine at the neuromuscular junction of striated muscles and thus produce chemical denervation and paralysis of the muscles. Our purpose of study is to know if application of botulinum toxin type A on calf reduction is effective, how much dosage is effective, and what are the possible complications. We reviewed data of 30 consecutive patients subjected to calf reduction in Dong-A University Hospital from February 2003 to April 2003. We injected normal saline 2cc on both calves region in 15 control group patients, and the other patients was divided 3 group. Group 1, Group 2, Group 3 was injected 50U, 100U, 150U botulinum toxin A on each calf region and followed up for 6 month. Maximal circumference of calf was not changed in the control group but an average of 0.7 cm reduction was noted in group 1, average 1.34 cm(right calf) and 1.26cm(left calf) in group 2, average 1.44cm(right calf) and 1.58cm(left calf) in group 3. Maximal area of calf was not changed in the control group but average reduction of 12.5%(right calf) and 12.7%(left calf) was obtained in group 1, average 19.4% (right calf) and 19.9%(left calf) in group 2, average 24.8%(right calf) and 21.07%(left calf) in group 3, as measured on CAT scan. Total fat amount and fat amount in the lower extremity was no change in all the groups, but lean body mass was decreased average 1.27%(right calf) and 1.15%(left calf) in group 1, average 3.47%(right calf) and 2.98%(left calf) in group 2, average 3.58%(right calf) and 3.95%(left calf) in group 3. Photography of the preoperative and postoperative 6 month state revealed higher satisfaction in Group 2, 3 compared to Group 1. Use of botulinum toxin type A in calf reduction is a very simple, safe, non-invasive method and effective in terms of calf contouring rather than reduction of calf circumference.

• 대한디지털의료영상학회논문지
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• 제10권1호
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• pp.45-50
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• 2008

Recently, MR Cholangiography used mainly bu controlling of patient's breathing. There is breathing hold techniques to get images within shopt time and gating technique adjusted to respiration cycle for high resolution image. In this study, the aim of this experiment is to know on clinical usefulness compared with PACE and RTG thchniques. This study's period is from 2006 in November to 2007 in January. A total of 21 patients investigated at MAGNETOM Sonata 1.5T (SIEMENS Erlangen) with use of 12ch body coil. MR acquisition protocol used 3D turbo spin echo coronal sequence. Scan parameters applied to potimal setting in use as gating techniques, respectively. Analysis of consuming timing evaluated with rapidness. As analysis of quantity, the common bile duct, gall bladder measured in signal intensities, then these data were calculated by signal to noise ratio and contrast to noise ratio. Qualitative analysis, experienced 2radiologists and 3 RTs were evaluated into 3groups about artifact, accuracy of lesions, sharpness of the common bile duct or gall bladder. As a result of analysis, when compared to PACE, consuming time of the RTG took less than PACE, On both CNRs and SNRs, PACE technique was slightly high values than RTG(p<0.05). Qualitative analysis' results, discrimination of lesions in the common bile duct, gall bladder get a significance level in both RTG and PACE techniques but presence's artifact of breathing and pulsation highly demonstrate in PACE techniques. In conclusion, both PACE and RTG methods at MRCP provided prominently clinical information for the common bile duct, gall bladder. If machines have not limitation with performance, induction of breathing holding also will help getting diagnistic quality.

• 한국지능시스템학회논문지
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• 제26권6호
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• pp.433-438
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• 2016

본 논문에서는 한우의 근내 지방 부분을 초음파 기기를 이용하여 촬영한 초음파 영상의 특징 분석을 통해 classification 알고리즘을 이용하여 한우의 도체육질 등급을 예측하는 방법을 제안하며, 인체의 초음파 영상을 이용하여 진단 및 치료 검증 과제에 있어 사전 연구로 진행된 연구로, 차후에는 초음파 영상의 분석 범위를 확대할 예정이다. 한우의 초음파 영상을 활용한 경우에는 생체 정보를 한우 개량의 측면에서 생체 육질 정보를 조기에 획득하여 활용함으로써, 도축하지 않고도 육질 및 육량을 측정하여 개량의 속도를 배가시킬 수 있고, 농가 경영 측면에서 출하시기 및 방법의 조절로 농가 수익향상에 일조할 수 있는 중요한 핵심 기술이다. 이에 대한 많은 연구가 미국과 일본을 중심으로 이루어져 왔으며, 특히 기기에 의한 객관적인 측정방법들이 다양하게 연구되고 있지만 정확도가 낮다. 따라서 제안된 연구에서는 한우의 근내 지방 초음파 영상에 특징점 추출 알고리즘과 classification 알고리즘을 적용하여 한우의 도체 육질을 예측하였다. 실험 결과 제안하는 방법을 적용하였을 경우, 기존의 방법에 비해 효율적인 것을 확인할 수 있었다.

• 대한방사선기술학회지:방사선기술과학
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• 제44권2호
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• pp.91-100
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• 2021

High-Resolution thoracic CT (HRCT) is a scanning protocol in which thin slice thickness and sharpness algorithm are utilized to enhance image resolution for diagnosis and assessment of interstitial lung disease (ILD). This examination is sometimes performed in both supine and prone position to improve sensitivity to early changes of these conditions. Anatomical structures (the size of lung field and heart and descending aorta) of 150 patients who underwent HRCT were retrospectively compared. HRCT had been conducted in two positions (supine and prone). Data were divided into five groups according to patient body weights (from 40 to more than 80kg, 10kg intervals, 60 patients/each group). Quantitative analysis was utilized in Image J program. In the supine position defined as the control group, the average values of lung fields and heart size and aorta were compared with the prone position defined as the experimental group. The size of the lungs was found to be higher in the supine position, and it was confirmed that there was a statistically significant difference in patients over 70 kg (p<0.05). In addition, both sizes of the heart and descending aorta were larger in prone position, but in the case of the heart, there was no correlation with the presence or absence of ILD disease (p>0.05). Also, the area of prone in the descending aorta was higher than supine position, but there was no statistically significant difference between supine and prone position (p>0.05). In conclusion, when the severity of ILD disease was severe, there was no statistically significant difference in the area difference between supine and prone position, so it is considered that it will be helpful in diagnostic decision.

• Korean Journal of Radiology
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• 제25권2호
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• pp.179-188
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• 2024

Objective: ¹⁷⁷Lutetium [Lu] Ludotadipep is a novel prostate-specific membrane antigen targeting therapeutic agent with an albumin motif added to increase uptake in the tumors. We assessed the biodistribution and dosimetry of [¹⁷⁷Lu]Ludotadipep in patients with metastatic castration-resistant prostate cancer (mCRPC). Materials and Methods: Data from 25 patients (median age, 73 years; range, 60-90) with mCRPC from a phase I study with activity escalation design of single administration of [¹⁷⁷Lu]Ludotadipep (1.85, 2.78, 3.70, 4.63, and 5.55 GBq) were assessed. Activity in the salivary glands, lungs, liver, kidneys, and spleen was estimated from whole-body scan and abdominal SPECT/CT images acquired at 2, 24, 48, 72, and 168 h after administration of [¹⁷⁷Lu]Ludotadipep. Red marrow activity was calculated from blood samples obtained at 3, 10, 30, 60, and 180 min, and at 24, 48, and 72 h after administration. Organand tumor-based absorbed dose calculations were performed using IDAC-Dose 2.1. Results: Absorbed dose coefficient (mean ± standard deviation) of normal organs was 1.17 ± 0.81 Gy/GBq for salivary glands, 0.05 ± 0.02 Gy/GBq for lungs, 0.14 ± 0.06 Gy/GBq for liver, 0.77 ± 0.28 Gy/GBq for kidneys, 0.12 ± 0.06 Gy/GBq for spleen, and 0.07 ± 0.02 Gy/GBq for red marrow. The absorbed dose coefficient of the tumors was 10.43 ± 7.77 Gy/GBq. Conclusion: [¹⁷⁷Lu]Ludotadipep is expected to be safe at the dose of 3.7 GBq times 6 cycles planned for a phase II clinical trial with kidneys and bone marrow being the critical organs, and shows a high tumor absorbed dose.

• 대한방사선기술학회지:방사선기술과학
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• 제30권4호
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• pp.381-389
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• 2007

본 연구는 전산화단층촬영 검사의 방사선 선량에 관하여 조사하고자 하였다. 이를 위하여 문헌고찰을 실시하였으며, 여러 기관으로부터 자료를 수집하였고, 각 의료기관의 CT장비에서 선량을 측정하였으며, 병원에서 시행하고 있는 Protocol에 입각하여 피폭선량을 계산하였다. 이 연구의 주요 결과는 다음과 같다. 1. 두부팬텀을 이용하여 측정된 100 mAs 당 $CTDI_W$ 값은 4 slice MDCT 장비가 24.20 mGy로 가장 높았다. 장비의 세대별 구분에 따른 $CTDI_W$ 값은 통계적으로 유의한 차이가 있었다(p < 0.01). 2. 복부팬텀을 이용하여 측정한 100 mAs 당 $CTDI_W$ 값은 4 slice MDCT 장비가 13.58mGy로 가장 높았으며, $CTDI_W$ 값은 장비 세대별로 통계적으로 유의한 차이가 있었다(p<0.01). 3. 두부검사에서의 환자선량은 조영제를 사용하지 않을 경우에 가장 높은 장비는 16 slice MDCT로 $818.83\;mGy{\cdot}cm$이었다(p < 0.05). 조영제를 사용하는 경우는 4 slice MDCT 장비에서 $1460.77\;mGy{\cdot}cm$로 가장 높게 측정되었으며, 평균 환자선량은 장비 종류 사이에 유의한 차이가 있었다(p < 0.1). 4. 흉부검사에서의 환자선량은 조영제를 사용하지 않을 경우에 16 slice MDCT에서 평균은 $521.63\;mGy{\cdot}cm$로 가장 높았으며, 장비종류별로 유의한 차이가 있었다(p < 0.05). 조영제를 사용하는 경우에 8 slice MDCT 장비에서의 환자선량이 평균 $1,174.70\;mGy{\cdot}cm$로 가장 높았으며, 장비별로 평균 환자선량에는 통계적으로 유의한 차이는 없었다. 5. 복부-골반검사에서 조영제를 사용하지 않을 경우에 환자선량이 가장 높은 장비는 16 slice MDCT 장비로 평균은 $856.27\;mGy{\cdot}cm$이었으며, 평균 환자선량은 장비 사이에 유의한 차이가 있었다(p < 0.05). 조영제를 사용하는 경우 환자선량이 가장 높은 장비는 16 slice MDCT로 평균 $1,720.64\;mGy{\cdot}cm$이었다. 평균 환자선량은 장비 사이에 유의한 차이가 있었다(p < 0.05). 6. 간 검사에서 조영제를 사용하지 않을 경우에 환자선량이 가장 높은 장비는 8 slice MDCT로 평균 환자선량은 $612.07\;mGy{\cdot}cm$이었고, 환자선량은 장비사이에 유의한 차이가 있었다(p < 0.05). 조영제를 사용하는 경우의 환자선량은 8 slice MDCT 장비의 평균이 $2,197.93\;mGy{\cdot}cm$로 가장 높았으며, 장비사이에 유의한 차이가 있었다(p < 0.1). 조사대상 의료기관의 76.2%에서 조영제를 투여하는 검사의 반복횟수가 $3{\sim}4$회로 방사선피폭에 의한 위험이 있을 것으로 추정되었다.

• 핵의학기술
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• 제16권1호
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• pp.12-16
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• 2012

서론: 종래의 PET 영상 재구성에 있어서 FBP 등에 비해 3차원 반복 재구성 방법이 일반적으로 대체하고 있으며, 이것은 검출기 기하학적 특성과 완벽한 3차원 산란 평가 및 저잡음 randoms 평가 등의 더 진보된 재구성 알고리즘을 제공하고 활용되고 있다. 최근에 SharpIR알고리즘은 3차원 반복 재구성 알고리즘으로 PET 검출기 응답 정보를 통합하여 PET 영상의 잡음을 효과적으로 감소시켜 대조도를 향상 시키기 위한 것으로 알려지고 있다. 본 연구에서는 새로운 반복 시스템 모델인 SharpIR에 대한 성능 평가와 임상에서의 적용 가능성에 대해 알아보고자 한다. 실험재료 및 방법: 검출기 응답에 대한 분해능을 측정하기 위해 유리관(내경 1.1 mm, 두께 0.2 mm)에 $^{18}F$-FDG (250 MBq/mL)을 주입하여 축 방향 시야의 중심과 축 방향으로 5, 10, 15, 20 cm만큼 떨어진 지점에서 획득하였고 VUE point HD와 VUE point HD-SharpIR로 재구성하여 각각의 영상에서 반치폭을 구하였다. 또한 영상품질평가로 image quality phantom (NU2-2001)을 이용하여, 여러 개의 각각 다른 반지름을 가지는 원형구에 cold (직경 28, 37 mm)와 ho (직경 10, 13, 17, 22 mm)부분을 나누어 배경잡음을 주고 영상의 대조도를 평가하였다. 획득된 영상은 VUE point HD와 VUE point HD-SharpIR로 재구성을 하였다. 임상실험에서는 전신검사를 시행받은 환자 중 병소가 있는 환자 10명을 대상으로 VUE point HD와 VUE point HD-SharpIR로 재구성하였다. 이때 iterations을 1~10까지 변경하여 병소 부위와 간 부위에 관심영역을 설정하여 대조도를 평가하였다. 결과: VUE point HD로 재구성한 영상에서는 시야 중심으로부터 축방향 거리 증가와 함께 반치폭이 함께 증가하였지만 VUE point HD-SharpIR로 재구성한 영상에서는 거리가 증가하여도 일정한 반치폭을 나타냈다. 대조도는 팬텀 실험과 임상 실험에서 VUE point HD-SharpIR이 VUE point HD보다 대조도의 향상을 나타냈다. 결론: 검출기 시스템 응답에 대한 더 많은 정보를 포함시킴으로써 SharpIR 알고리즘은 VUE point HD에서 사용되는 기본 모델의 정확성을 향상시켰다. 또한 SharpIR은 VUE point HD보다 각각의 복셀에 관련된 더 많은 측정 위치를 가지는 시스템 모델이기 때문에 더욱 정교한 재구성 모델의 결과를 나타내기 위해 더 많은 반복이 걸린다. 결론적으로 SharpIR은 PET 영상에서 대조도를 향상시켰고 임상에서 적용할 수 있는 최적화된 재구성 조건을 알아보기 위해 종단적 연구를 통해 적용한다면 임상에서 유용하게 사용될 것이다.