• Bulletin of the Korean Chemical Society
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• 제35권9호
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• pp.2625-2629
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• 2014

Platelets are anuclear discoid-shaped blood cells with key roles in human body. To understand the mechanisms of their activation process, it is required to have analytical imaging techniques capable of acquiring platelet images under fully hydrated conditions. Herein, for the first time, we demonstrate the capability of synchrotron-based transmission X-ray microscopy (TXM) to study platelets (resting and ADP activated) under hydrated and air-dried conditions. To confirm the biological imaging capability of TXM, fixed platelets were imaged and compared with whole mount electron microscopy (EM) images. TXM provided morphological information with sufficient spatial resolution with simple and quick sample preparation procedure. We also observed temporal changes during the platelet activation, which initially had a discoid shape (0 s), formed pseudopodia (30 s) and generated a network of fibrin (5 min). Our results clearly demonstrate the potential of TXM technique to study fully hydrated biological samples under in situ conditions.

• 한국자동차공학회논문집
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• 제7권7호
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• pp.136-148
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• 1999

Detailed mathematical models of hybrid drivertrain components are presented and numerical simulations are carried out to analyze the shift characteristics and to improve the driving comfortability when the hybrid drivetrain is applied at the vehicle . Theoretical results are compared with experimental ones from the dynamometer as same condition in order to prove the appropriateness of modeling . Adding the vehicle body modeling, included in the suspension and the engine mount, it is possible to predict the dynamic behavior and shift characteristics more actually when shifts are occurred by automated manual transmission(AMT). these additional results are also compared with the same simulation ones of internal combustion engined vehicle equipped conventional manual transmission. Hence, it can be expected that the hybrid vehicle with AMT has a good shift quality.

• BMB Reports
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• 제41권4호
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• pp.267-277
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• 2008

Insects mount a robust innate immune response against a wide array of microbial pathogens. The hallmark of the Drosophila humoral immune response is the rapid production of anti-microbial peptides in the fat body and their release into the circulation. Two recognition and signaling cascades regulate expression of these antimicrobial peptide genes. The Toll pathway is activated by fungal and many Gram-positive bacterial infections, whereas the immune deficiency (IMD) pathway responds to Gram-negative bacteria. Recent work has shown that the intensity and duration of the Drosophila immune response is tightly regulated. As in mammals, hyperactivated immune responses are detrimental, and the proper down-modulation of immunity is critical for protective immunity and health. In order to keep the immune response properly modulated, the Toll and IMD pathways are controlled at multiple levels by a series of negative regulators. In this review, we focus on recent advances identifying and characterizing the negative regulators of these pathways.

• Ocean and Polar Research
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• 제26권3호
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• pp.481-486
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• 2004

A portable apparatus mounting Acoustic Doppler Current Profilers (ADCP) to any small boat was developed to effectively measure currents in shallow and narrow coastal seas like the west coasts of Korea. Characteristics of the apparatus is that an underwater fish-shaped body protecting an ADCP is designed to reduce the drag during the cruise, which can be freely mounted and detached from a boat with a clamp. Several cruise outputs prove themselves that the apparatus is properly designed for the intended purpose, to minimize air bubbles and to control the submerged depth of the sensor.

• 소음진동
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• 제9권1호
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• pp.97-102
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• 1999

Structure-borne noise is an important aspect to consider during the design and development of a vehicle. In this work. it was desired to identify the primary paths associated with structure-borne noise generated from the engine and front suspension. An experimental source-path-receiver model was used to characterize the system. A variety of primary sources such as engine. tires or exhaust system generate vibrations of the inner surfaces of the passenger compartment of a vehicle which subsequently radiate noise. The source was characterized by the force acting at the engine-to-body interface. and the path was characterized by pressure over force FRF's. The excitation forces were indirectly determined using dynamic stiffness of rubber mount or the system accelerance matrix. Through these analysis, path contribution diagram which is well expressed primary noise path is obtained.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2000년도 춘계학술대회논문집
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• pp.291-298
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• 2000

This paper describes a theoretical and experimental investigation into an active vibration isolation system in which four electromagnetic actuators are installed in parallel with each of four passive mounts placed between a piece of equipment and a vibrating base structure. Decentralised velocity feedback control is employed, where each actuator is operated independently by feeding back the absolute equipment velocity at the same location. Although one end of each actuator acts at the sensor positions on the equipment, the control system is not collocated because of the reactive forces acting on the flexible base structure, whose dynamics are strongly coupled with the mounted equipment. Isolation of low frequency vibration is considered where the equipment can be modelled as a rigid body and the mounts as lumped parameter springs and dampers. Control mechanisms are discussed, and some experimental and simulation results are reported.

• 정보학연구
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• 제9권1호
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• pp.9-19
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• 2006

Medications or conitive-behavior methods have been mainly used as a treatment of alcoholism. lately the virtualy technology has been applied to the kink of alcoholic disorders. A virtual environment makes him having avility to over come the drink. In this study, we were implemented by making panorama images and 3D object modules using 3D MAX, VRML, JAVA. And the BAR stimulator that composed with a position sensor, head mount display, and audio system, is suggested. To illustrate the physiological difference between a person who has a alcoholism and without a liquor bottle, heart rate was measured during experiment, and also measured a person's HR after the virtual reality training. The system measures the Physiological signals such as ECG, Temperature, analyzes those data automatically. The system has two parts, one is physiological data acquisition part which gets the body signal, and the other one is mobile nuit which includes signal processing and transmission functions, And Bluetooth allows two parts to communicate with each other. we demonstrated the subjective effectiveness of virtual reality psychotherapy through the clinical experiment.

• 한국임상수의학회지
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• 제37권5호
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• pp.242-248
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• 2020

An intestinal strigeiid trematode, Apharyngostrigea pipientis, was detected from Ardea cinerea jouyi, Egretta intermedia and Nycticorax nycticorax between July, 2006 and June, 2020 in Daejeon metropolitan city and Kangwon-do, Republic of Korea. It was observed with a light and scanning electron microscope (SEM), and molecularly analyzed with 18S rRNA genes. The infection rate of the strigeiid trematode was 25.9% (7/27). The body is cylindrical in whole mount, greatly elongated in outline and shows a strong dorsal curvature. The overall measurements are: length 4.1-4.8 mm; fore-body 1.00-1.20 mm by 0.8-0.9 mm; hind-body 3.2-3.6 mm by 0.43-0.46 mm. The body is covered by a relatively thick cuticle, devoid of spines. The oral sucker leads into a short esophagus that is devoid of a muscular pharynx. The holdfast organ is enormously developed. The vitelline follicles distributed dorsal wall of fore-body and hind-body. This strigeiid trematode especially differs from other species of genus Apharyngostrigea in morphology. Although these A. pipientis are several morphological distinctions from Apharyngostrigea cornu, the partial sequence of 18S rRNA showed the sequence homology of A. pipientis (99.9%) and A. cornu (99.8%), and this result revealed their conspecific relationship between A. cornu and A. pipientis. This is the first report of A. pipientis in the Republic of Korea.

• 대한전기학회논문지:시스템및제어부문D
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• 제50권7호
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• pp.313-317
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• 2001

This paper proposed a fuzzy logic cross coupled controller which can enhance the path tracking performance of optically guided AGV(Automated Guided Vehicle). The AGV follows the guide path, it cannot be avoid the deviation from the path due to the inevitable error and the deviation must be corrected. Optically guided AGV used in industrial area is controlled by On-Off controller generally, the experimental AGV has three optical sensors in front body. In this structure, we could not know the leaving distance accurately and steering angle from the guided line, so AGV could not be controlled properly with conventional controller in the case of increasing or decreasing velocity. If we mount additional sensors the AGV, we could know the leaving distance and steering angle from the guided line and proper error compensating methode can be applied. But because cost of sensors are high, the cost of total system is increasing. So, in this paper, to improve the tracking performance of AGV which has the minimum number of sensors and fuzzy logic cross coupled controller is proposed. Some simulations and experimental results are presented to illustrate the performance of the proposed controller.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 춘계학술대회논문집
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• pp.648-655
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• 2005

The resilient mounts of a diesel engine installed onboard a ship should be designed for both static and dynamic loads. If possible, the resonance frequencies of the six rigid body modes of the installation and the flexible modes of the engine support structure should not lie within the engine operation range. In this paper a design criterion is proposed to evaluate an isolation system which involves the summation of dynamic forces transmitted through the resilient mounts and elastic potential energy index stored in the mounts. A case study is also presented in which a diesel engine generator, which had an elastic foundation and was mounted in a 5500 TEU container vessel, was studied both theoretically and experimentally. The theoretical analysis of the test model was performed by using a single mass 6 degree of freedom system. Actual measurements of mechanical vibration of the Engine and its foundation onboard were carried out, which showed the importance of including the flexibility of the engine support structure in the mode