• Archives of Plastic Surgery
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• 제41권1호
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• pp.63-70
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• 2014

Background Perforator flaps minimize abdominal site morbidity during autologous breast reconstruction. The purpose of this study was to assess whether the number of perforators harvested influences the overall deep inferior epigastric perforator (DIEP) flap survival and flap-related complications. Methods A retrospective review was performed of all DIEP flaps performed at the Hospital of the University of Pennsylvania from 2006 to 2011. The outcomes assessed included flap loss and major complications. We compared flaps by the number of total perforators (1-4) and then carried out a subgroup analysis comparing flaps with one perforator to flaps with multiple perforators. Lastly, we conducted a post-hoc analysis based on body mass index (BMI) categorization. Results Three hundred thirty-three patients underwent 395 DIEP flaps. No significant differences were noted in the flap loss rate or the overall complications across perforator groups. However, the subgroup analysis revealed significantly higher rates of fat necrosis in the case of one-perforator flaps than in the case of multiple-perforator flaps (10.2% vs. 3.1%, P=0.009). The post-hoc analysis revealed a significant increase in the flap loss rate with increasing BMI (<30=2.0%, 30-34.9=3.1%, 35-39.9=3.1%, >40=42.9%, P<0.001) in the DIEP flaps, but no increase in fat necrosis. Conclusions This study demonstrates that the number of perforators does not impact the rate of flap survival. However, the rate of fat necrosis may be significantly higher in DIEP flaps based on a single perforator. Multiple perforators should be utilized if possible to decrease the risk of fat necrosis.

• 디지털융복합연구
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• 제12권10호
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• pp.587-595
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• 2014

본 연구의 목적은 비만흡연자의 복합운동이 당뇨발생예측률 및 신체조성, 혈관탄성에 미치는 영향을 분석하여 비만흡연자의 건강한 삶을 위한 효과적인 운동프로그램을 제시하는데 있다. 본 연구의 취지를 충분히 설명하고 자발적 참여의 동의서를 작성한 D광역시에 소재한 H기업체의 협력업체 T기업에 근무하는 40대 비만흡연 사원 20명이었으며, 과거병력과 현재 특별한 질환이 없고 규칙적인 운동경험이 없는 자들로 구성하였다. 이들은 당뇨발생률예측률 및 신체조성, 혈관탄성 검사를 실시하였으며, 실험 전과 12주간 복합운동 실시 후 평균과 표준편차를 산출하기 위하여 기술통계를 실시하였고 실험 전 후 차이 검증은 Paired t-test를 이용하여 분석하였다. 통계적 유의수준은 p<.05로 설정하여 다음과 같은 결론을 얻었다. 12주간 복합운동프로그램 참여 후 당뇨발생예측률, 체중, 체지방률, 골격근량, 복부지방률 및 혈관탄성 상지(오른손, 왼손), 하지(오른발, 왼발)에서 통계적으로 유의한 수준의 변화를 보였다(p.<05).

• Journal of Nutrition and Health
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• 제25권6호
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• pp.485-491
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• 1992

남성호르몬인 testosterone 투여가 정상 암컷쥐의 체중, 체구성성분(체단백질, 체지방), 에너지 대사 및 근육단백질 대사에 미치는 영향을 조사하였다. Testosterone propionate를 체중 1kg당 1mg(1mg/kg)으로 10일간 투여했을 때 식이섭취량은 변화하지 않았음에도 체중 및 체단백질, 체지방은 유의적으로 증가하였다. 반면 testosterone propionate를 4번 또는 10mg/kg으로 투여 시에는 체단백질만 유의적으로 증가하였고 체지방은 영향을 받지 않았다. Testosterone propionate에 의한 체내 에너지축적(energy gain) 및 에너지 이용율(gross energetic effciency) 증가는 1mg/kg의 투여량에서만 관찰되었다. 근육조직(gastrocnemius muscle)의 무게, 단백질 및 RNA함량은 모든 투여량에서 유의적으로 증가하였으나 단백질 합성율은 어느 투여량에서도 영향을 받지 않았다. 이러한 결과를 통해 testosterone이 체중 및 체단백질, 체지방에 미치는 영향은 투여량에 크게 의존하며 testosterone의 근육단백질 증진 효과는 단백질 합성율에는 영향을 미치지 않고 단백질 분해율을 저하시킴으로써 발휘된다는 것을 알 수 있다.

• 한방재활의학과학회지
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• 제18권4호
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• pp.171-187
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• 2008

Objectives : The purpose of this study was to investigate the effects of modified fasting therapy on body composition, blood cell count and blood chemistry in inpatients. Methods : The modified fasting therapy program consists of three phases, a period of reducing food intakes, fasting and refeeding. Body weight, body composition, and the degree of obesity were estimated in before fasting therapy and after refeeding. Blood cell count and blood chemistry were estimated in before fasting therapy, before refeeding and after refeeding. Results : After modified fasting therapy, body weight, body fat mass, percent body fat, body mass index(BMI), body matabolic rate(BMR) and muscle mass was decreased significantly. WBC count and platelet count decreased significantly, RBC count and hemoglobin increased significantly and hematocrit was not changed significantly but within normal limit. AST and ALT increased significantly, especially patients group over BMI 25 within normal liver function. This study was not founded correlation between decreased muscle mass and increased liver function test. ALP, BUN, Total-cholesterol, and triglyceride decreased significantly. Creatinine increased significantly, but within normal limit. Sodium was not changed significantly, potassium decreased significantly but within normal limit. Conclusions : These results suggest that modified fasting therapy will be beneficial if several measures complement.

• 대한한의학회지
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• 제45권1호
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• pp.65-79
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• 2024

Objectives: The purpose of this study is to evaluate weight change and analyze adverse events in post-menopausal obese women with Gamitaeeumjowee-tang for weight loss. Methods: A retrospective chart review was conducted for medical records of 115 post-menopausal obese women (body mass index, BMI≥25 kg/m²) who were administered with Gamitaeeumjowee-tang for 12 weeks for the purpose of weight loss. Weight, skeletal muscle ratio and BMI changes were compared before and after the program. Adverse events were evaluated by causality, severity and system-organ classes. Results: A total of 115 patients were included in this study. The average total weight loss in post-menopausal women was 5.72±2.04kg(p<0.001) and the average weight loss rate was 8.06±2.70%(p<0.001). After the 12-week program, the body fat rate was significantly decreased(3.76±2.20%)(p<0.001) and the skeletal muscle ratio was significantly increased(2.07±1.24%)(p<0.001). There were no significant differences in weight loss, skeletal muscle ratio change and body fat rate change depending on the number of hospital visits. Insomnia was frequently reported throughout the period, and no serious adverse events were reported. Conclusions: This study showed the potential that weight management treatment with Gamitaeeumjowee-tang could be a good way to lose weight of post-menopausal obese women without serious adverse events. Continuous well designed clinical studies are needed.

• 대한지역사회영양학회지
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• 제18권5호
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• pp.525-538
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• 2013

The purpose of this study was to provide information on obesity assessment for Koreans. Among total of 1012 research papers enlisted in the Korean J Community Nutrition form 1996 to 2011, 248 articles were examined in which subjects were divided into more than 2 groups by obesity rate. About the method of anthropometric data collection, more than half of the research papers examined 52.5% and 28.7% of studies utilized the directly measured data and self-described data, respectively. About the utilization of obesity assessment methods, indirect methods of weight-height index (BMI, BMI percentile, and R$\ddot{o}$hrer index) and PIBW (WLR, Broca index, and KDA) were 62.4% and 23.2%, respectably, and the direct method of percent body fat assessment was only 9.3%. The most frequently utilized methods were WLR in under primary and primary school children, and BMI in the middle and high school students and in adults. For primary school students, WLR was the most frequently utilized method up to 2007, but it changed to BMI percentile afterward. Broca Index was no longer utilized since 2008. There were no articles utilizing BMI percentile and R$\ddot{o}$hrer index for obesity assessment in adults. Criteria for obesity assessment were not consistent among research papers: for example, % body fat, 19~40%; BMI, 20~30; BMI percentile, 85th or 95th. In the case of PIBW, 120% of ideal weight was the most frequently utilized criterion for obesity. Based on these findings, we suggest that proper methods and criteria of obesity assessment for each age group should be determined and proclaimed.

• 생명과학회지
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• 제13권4호
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• pp.448-456
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• 2003

유산소운동과 서어킷 웨이트 트레이닝이 호흡순환기능과 신체조성에 미치는 영향을 알아보기 위하여 P시에 거주하는 직장여성 16명을 대상으로, 8명을 운동군으로 나머지 8명을 통제군으로 하여 운동군에게는 1일 1시간씩, 주당 5일, 8주간의 유산소운동(70%∼80%HRmax)과 서어킷 웨이트 트레이닝(1RM의 40%∼50%)을 실시하였다. 두 군 모두 pretest와 posttest를 실시하여 호흡순환기능과 신체구성의 변화를 비교ㆍ분석한 결과, 운동군에서는 안정시의 심박수는 유의하게 감소하였고(p<.001), 산소섭취량, 환기량 그리고 폐활량은 유의하게 증가하였다(p<.001). 최대운동시 산소섭취량도 운동군에서는 유의한 증가가 나타났다(p<.001). 또한 운동군에서는 체지방률과 체지방량은 유의하게 감소한(p<.001) 반면 제지방률과 제지방량은 유의하게 증가하였다(p<.001). 이상의 결과에서 유산소운동과 저항성운동의 복합 프로그램은 직장여성의 심폐기능 향상과 체지방 감소에 긍정적인 영향을 미치는 것으로 나타났다.

• 생명과학회지
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• 제18권6호
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• pp.865-870
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• 2008

운동과 식이요법을 병행한 체중감량 프로그램에 참여한 여성 비만인의 체지방량, 안정시대사량, 그리고 갑상선 호르몬 차이를 비교할 목적으로 실험한 결과, 체지방량, 체지방율, 체표면적이 유의하게 감소되었고, 안정시대사량 예측치와 실측치 모두 유의하게 감소되었지만, 갑상선 호르몬의 변화는 나타나지 않았다. 안정시대사량과 신체요인들과의 상관분석 결과, 제지방 체충이 가장 밀접한 관계를 보였으며, 안정시대사량과 갑상선 호르몬들과의 관계에서는 TSH와 가장 밀접한 관계를 나타내었다. 결론적으로 8주간 체중감량 프로그램 참여로 체지방은 효과적으로 감소되었으나, 갑상선 호르몬 차이는 없었고 체중감소에 비해 제지방이 유지됨으로써 안정시대사량의 감소는 최소화되어, 에너지 대사작용에 긍정적인 영향을 준 것으로 사료된다.

• 대한예방한의학회지
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• 제11권1호
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• pp.65-84
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• 2007

In this study, the researcher tried to present the groundwork to prepare the oriental medical yangseng plan for the future obesity with the comparison between yangseng level and the obesity of workers. The researcher made up the questionnaire which asks the general character, health-related character and yangseng level, projected among 560 people. All collected material was analyzed by SPSS and tested by T-test and ANOVA. 1. The general yangseng level average is 3.27, morality yangseng 3.90, sleep yangseng 3.39, mind yangseng 3.31, sex life yangseng 3.30, exercise yangseng 3.15, activities and rest yangseng 3.08, diet yangseng 2.94, seasonal yangseng 2.84. The highest is morality yangseng and seasonal yangseng is the lowest. 2. In the aspect of yangseng level: Having a spouse, Non-smoking, Regular exercising, Sufficient sleeping have higher yangseng levels. 3. Obesity related index is changing into the higher level when he/she is older, more paid, more job experience, more education background but less metabolic calory. And drinking and regular exercising have relativity with body composition analysis. 4. After comparing yangseng level with body composition analysis, we can easily find that the more visceral fat, the higher WHR has a high yangseng level. The more mineral also has a high mind yangseng and a low diet yangseng. The visceral fat level has a high yangseng level when higher morality yangseng and mind yangseng are getting higher and higher. And sex life yangseng shows that the highest yangseng level is from 9-10 visceral fat and the lowest yangseng level is from below 4 visceral fat. The higher WHR, the higher morality, mind and sleep yangseng. The heavier, the lower diet yangseng. The mind yangseng was very high when body fat rate was higher. The more body fat, the higher morality yangseng. The higher yangseng, when we have more muscle. Yangseng level and obesity of laborer has a close relationship with individual character and daily habits. Also, relevance can be easily found between yangseng level and obesity. Now the researcher came into the conclusion that we need to control over laborers' health and prevention of their obesity.

• 대한의료기공학회지
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• 제10권1호
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• pp.46-73
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• 2007

In this study, the researcher tried to present the groundwork to prepare the oriental medical yangseng plan for the future obesity with the comparison between yangseng level and the obesity of workers. The researcher made up the questionnaire which asks the general character, health-related character and yangseng level, projected among 560 people. All collected material was analyzed by SPSS and tested by T-test and ANOVA. 1. The general yangseng level average is 3.27, morality yangseng 3.90, sleep yangseng 3.39, mind yangseng 3.31, sex life yangseng 3.30, exercise yangseng 3.15, activities and rest yangseng 3.08, diet yangseng 2.94, seasonal yangseng 2.84. The highest is morality yangseng and seasonal yangseng is the lowest. 2. In the aspect of yangseng level: Having a spouse, Non-smoking, Regular exercising, Sufficient sleeping have higher yangseng levels. 3. Obesity related index is changing into the higher level when he/she is older, more paid, more job experience, more education background but less metabolic calory. And drinking and regular exercising have relativity with body composition analysis. 4. After comparing yangseng level with body composition analysis, we can easily find that the more visceral fat, the higher WHR has a high yangseng level. The more mineral also has a high mind yangseng and a low diet yangseng. The visceral fat level has a high yangseng level when higher morality yangseng and mind yangseng are getting higher and higher. And sex life yangseng shows that the highest yangseng level is from 9-10 visceral fat and the lowest yangseng level is from below 4 visceral fat. The higher WHR, the higher morality, mind and sleep yangseng. The heavier, the lower diet yangseng. The mind yangseng was very high when body fat rate was higher. The more body fat, the higher morality yangseng. The higher yangseng, when we have more muscle. Yangseng level and obesity of laborer has a close relationship with individual character and daily habits. Also, relevance can be easily found between yangseng level and obesity. Now the researcher came into the conclusion that we need to control over laborers' health and prevention of their obesity.