• Title/Summary/Keyword: Blood sugar levels

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Effects of Water Extract of Antler(AE) on Blood Sugar Levels in Normal Albino Rats and a Hereditary Diabetic Strain of Murine, KK-mice (녹용(Cervi Cornu)추출액이 정상백서 및 자발성 당뇨병동물(KK mice)의 혈당량에 미치는 영향)

  • Kim, Kee-Soon
    • The Korean Journal of Physiology
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    • v.17 no.2
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    • pp.183-190
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    • 1983
  • Effects of water extracts of antler on blood sugar levels were studied in normal rats and KK-mice. a spontaneously diabetic strain of murine. Blood sugar levels were determined at 30, 60, and 120 minutes after intraperitoneal administration of 1 ml/kg or 2ml/kg AE into normal rats. A moderate but significant decrease in blood sugar level was noticed only in 30 minutes following 2 ml/kg AE administration. On the other hand no significant changes in blood sugar level was observed in KK-mice to which 1ml/kg/day AE had been given for 10 weeks. The results of present study strongly indicate that antler extract exerts no significant effect on blood sugar levels in experimental animals.

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Studies on a New Alimentotherapy for Diabetic Patients (당뇨환자를 위한 새로운 식이요법제에 관한 연구)

  • 라정찬;배진희;박형근;강경선
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.4
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    • pp.614-620
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    • 2003
  • Mulberry, Morifolium leaves and fruits, Lycii fructus, and Panax ginseng have been known to maintain normal blood sugar levels in folk medicine. Here we investigated the effects of coated rice (Sodangmi$^{TM}$) with these herb extracts to diabetes mellitus patients. Alloxan-induced diabetic mice (80 mg/kg bw, i.v.) separated into 4 groups. 2 groups received the mixed extracts of these plants (Sodans Extract$^{TM}$) orally everyday for 4 weeks. Positive control received Alloxan except Sodans Extract$^{TM}$. Negative control received neither Alloxan nor Sodang Extract$^{TM}$. Blood sugar levels, volume of water consumed, body weights of each group were measured and compared. Blood sugar levels in the Alloxan and Sodang Extract$^{TM}$-received groups got close to normal levels on 4th week after starting the experiments. Volume of water consumed also showed similar pattern. Blood sugar levels in positive control remained high through the experimental periods. Body weights in positive control remained low, but those in the extracts-received groups recovered to normal levels. The clinical trials for both of healthy volunteers and diabetes mellitus patients also showed Sodangmi$^{TM}$ could control blood sugar level. The blood sugar level decreased since 3rd week after starting to receive Sodangmi$^{TM}$, and the difference between the blood sugar level before and after the meal was decreased significantly by receiving Sodangmi$^{TM}$. From these results, we suggest that the functional rice with herb extracts could be used as a new alimentotherapy for diabetes mellitus patients.llitus patients.

A Comparative Study of the Fasting Blood Sugar between Homeless and Aged People of Nursing Home in Daegu City, Korea - Comparision of National Health Insurance Coporation Criteria -

  • Shin, Hyun Gyu
    • Korean Journal of Clinical Laboratory Science
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    • v.44 no.3
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    • pp.97-102
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    • 2012
  • This study was performed to investigate the average fasting blood sugar levels from various Homeless and the old at nursing homes. Subjects (297 Homeless and 190 aged people) were examined in April, 2011 to June, 2010 in Daegu city area and only fasting blood sugar was measured. Subjects consist of 274 (56.30%) men and 213 (43.70%) women but primarily comprise over 60s. Blood was collected by vein-puncture, centrifuged and analyzed by TBA-C8000. The number of each subject for blood sugar levels of men groups were shown 197 (40.50%) with under 110, 24 (4.90%) with 110~125, and 53 (10.90%) with over 126. On the other hand, 127 (26.10%) with under 110, 33 (6.80%) with 110~125 and 53 (10.90%) with over 126 from women groups. This means that the average prevalence rate of diabetes is approximately 10% at each sex. Depending on age, the fasting blood sugar level over 126 increased with advancing age but the significance of results was not shown. Two groups, Homeless and aged people at nursing homes, the fasting blood sugar level was alittle high (2.9%) from Homeless but not significant. Regular blood sugar test and HbA1c test for people could be play an important role to prevent diabetic disorders under the government's interest.

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The Estimation of Prevalence of Diabetes Mellitus in a Rural Adult Population (일부 농촌 성인의 당뇨병 유병률 추정)

  • Park, Sue-Kyung;Kim, Joung-Soon
    • Journal of Preventive Medicine and Public Health
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    • v.29 no.3 s.54
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    • pp.483-494
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    • 1996
  • The objectives of this study are to estimate the prevalence of diabetes mellitus (DM) and to identify risk factors associated with fasting blood sugar in a rural adult population. We carried out a cross - sectional study on the residents over 30-year old. Among the 1077 eligible subjects, 725 persons responded to the study;the study consisted of interview on family and past history of DM, anthropometry, blood pressure, and blood sugar level in each subjects. Only 707 subjects of 725 participants had fasting blood sugar(FBS) examined and the rest, 18 subjects were had casual blood sugar examined due to failure of fasting over 8 - hour. When subjects had $FBS\geq140mg/dl$, 2 hours postprandial blood sugar level was checked after 75g oral glucose loading. The prevalence of DM was 8.9%, and age standarized prevalence rate adjusted to Korean population of 1995 was 5.8%. Mean and SD of fasting blood sugar in men was $99.8{\pm}22.6$, and in women was $111.5{\pm}29.9$. Mean levels of fasting blood sugar were significantly higher in women than in man and as their ages advanced the prevalences increased in both sexes. PP2 blood sugar levels were significantly higher in elder age and in persons with higher FBS levels than others. The risk factors associated with FBS were past history of diabetes, sex, socioeconomic status and waist - to - hip circumference ratio;the risk of diabetes was increased in female, people with past DM history, central obesity and low socioeconomic state. The low socioeconomic status associated with DM in this study, which is different from other study results, should be pursued in further studies.

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Effect of Foot Reflex Massage on Stress Responses, and Glucose Level of Non-Insulin Dependent Diabetes Mellitus Patients (발반사 마사지가 인슐린 비의존성 당뇨병 환자의 스트레스반응과 혈당에 미치는 효과)

  • Kim, Keum-Soon
    • The Korean Journal of Rehabilitation Nursing
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    • v.6 no.2
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    • pp.152-163
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    • 2003
  • Purpose; This study was done to investigate the effect of foot reflexology on vital signs, general fatigue, foot fatigue, mood, and blood glucose levels in noninsulin dependent patients. Method: The Research design of this study was nonequivalent control group quasi-experimental design. 18 patients were assigned to the experimental group, 24 patients to the control group. The data were obtained diaberic patients with ambulatory endocrine outpatients clinic patients from 40 years old to 70 years old. Experimental groups received foot reflex massage for 30minutes three times/week every other days, and Control groups did not received foot reflex massage. The dependent variables were blood pressure, pulse rate, visual analogue scale for general fatigue, foot fatigue, mood, and blood sugar levels. Data were analyzed with $X^2$ test, t-test and repeated measure ANOVA at .0.05 level of significance. Results: There were significant difference in the pulse rate, general fatigue, foot fatigue and mood according to group and time between pre and post foot reflexology. But this research did not prove to decrease blood sugar levels. Conclusions : Foot reflexology can imorove pulse rate, general and foot fatigue, and mood status in diabetus patients. So further research need to explore the effect of decreasing of blood sugar levels.

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Effect of Physical Activity on Blood Sugar Control in Young and Middle-aged Diabetic Patients Using the 8th Korea National Health and Nutrition Examination Survey Data (국민건강영양조사 자료를 이용한 청년 및 중·장년층 당뇨병 환자의 신체활동량이 혈당조절에 미치는 영향 분석)

  • Tae-Hyeon Lee;Il-Su Park
    • Journal of The Korean Society of Integrative Medicine
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    • v.12 no.3
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    • pp.227-236
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    • 2024
  • Purpose : The number of young patients with diabetes is on the rise, and they face challenges in managing their blood sugar levels. This study aimed to investigate the effect of physical activity on blood sugar control in young and middle-aged patients with diabetes aged 19-64 years using data from the 8th Korea National Health and Nutrition Examination Survey (2019-2021). Methods : Blood sugar control in patients with diabetes was determined based on FBG 110 mg/㎗, and physical activity was measured using physical activity categories that considered the sum of walking, moderate intensity, and high intensity. Statistical analysis was conducted using SAS 9.4, and the Rao-Scott chi-square test was conducted to determine differences in blood sugar control based on the sociodemographic characteristics and physical activity of patients with diabetes. Complex-sample multiple logistic regression analysis was conducted to assess the effect of physical activity on blood sugar control. Results : There were statistically significant differences in blood sugar control between young and middle-aged patients with diabetes, depending on sex, age, marital status, obesity, and amount of physical activity. As a result of the complex sample simple logistic regression analysis without adjusting for variables, the non-physical activity group was found to have a higher risk of blood sugar dysregulation than the health-promoting physical activity group (OR: 2.80). Complex-sample multiple logistic regression analysis with control variables showed that the non-physical activity group had a higher risk of blood sugar dysregulation than the health-promoting physical activity group (OR: 3.70). Conclusion : Multifaceted efforts are needed to develop health intervention programs that can increase physical activity, diabetes awareness, and treatment rates, including controlling blood sugar levels and preventing complications in young and middle-aged patients with diabetes.

Correlation between Obesity Indices and Cardiovascular Risk Factors and Usefullness of Abdominal Obesity Indices (비만 지표와 심혈관계질환 위험인자간의 상관성 및 복부비만지표의 유용성)

  • Ha, Hun-Young;Choi, Bo-Youl;Park, Hung-Bae
    • Journal of Preventive Medicine and Public Health
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    • v.30 no.2 s.57
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    • pp.327-341
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    • 1997
  • It is a well known fact that obesity is an important cause of cardiovascular disease, emphasized by many studies. Recently, cardiovascular diseaase has been found to correlate not only to the extent of obesity, but also the fat distribution of the individual; especially, focusing on obesity of the abdomen. Unfortunately, the proposed indices for abdominal obesity are numerous, and the results vary according to the index chosen. Three-hundred and twelve bus drivers in November, 1995, were chosen as subjects of this study. The author chose to measure serum lipid levels, fasting blood sugar levels and blood pressure, that are thought to be important risk factors of cardiovascular diseases. Obesity indices were calculated using anthropometric measurements. We were able to evaluate the significance of obesity indices by examining correlations between these indices and the risk factors of cardiovascular disease. The results obtained were as follows: 1. The abdominal obesity indices and risk factors of cardiovascular disease, the levels of total cholesterol in the serum, fasting blood sugar levels, and diastolic blood pressure, increased significantly according to age. 2. There was a significant difference in the abdominal obesity indices according to drinking and smoking habits controlled for age. Among the risk factors of cardiovascular disease, triglyceride and diastolic pressures had significant differences according to the presence or absence of a drinking history controlled for age. 3. Although all obesity indices showed significant correlations, the weakest correlation was between BMI and abdominal diameter index and the strongest correlation was between sagittal diameter and sagittal diameter matched for height. 4. There was a negative correlation between HDL-cholesterol and obesity indices. The weakest correlation was between fasting blood sugar levels and both SD and SDH showed correlations with the risk factors. 5. There was a significant correlation between SD and total cholesterol in the serum and fasting blood sugars controlled for age, drinking, and BMI. 6. After categorizing the subjects into 2 separate age groups at the 40 year mark, in the less than 40 you old age group, controlled for drinking and BMI, the results of comparitive studies have shown correlations between total cholesterol serum levels and waist-hip ratio, conicity-index, and SD. There were correlations between fasting blood sugar levels and SD, ADI, and SDH. There were no correlations between obesity indices and both total cholesterol serum levels and fasting blood sugar levels in the greater than 40 year old age group. There were significant correlations between abdominal obesity indices and total serum cholesterol or fasting blood sugar levels in the less than 40 year old age group, but no correlations in the age group over 40. These correlated factors between abdominal obesity and cardiovascular disease are assumed to exist in Korea as well. Furthermore, in this study a high correlation was found between SD, SDH and the risk factors of cardiovascular disease. Even when controlled for age, drinking, smoking, and BMI, the correlations between risk factors of cardiovascular disease and these indices exist. Therefore, the obesity indices, SD and SDH may prove to be important prognostic indicators or risk factors of cardiovascular disease.

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Studies on the Hypoglycemic Effect of Ginseng Polypeptide

  • Wang, B.X;Yang, M.;Jin, Y.L.;Cui, X.Y.;Wang, Y.
    • Proceedings of the Ginseng society Conference
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    • 1990.06a
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    • pp.196-200
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    • 1990
  • the ginseng polypeptide (GPP) isolated from the root of Panax ginseng C.A. Meyer was demonstrated to decrease the levels of blood sugar and hepatic glycogen when injected intravenously to rats at a doses of 50-200mg/kg without affecting blood total lipid. When mice were injected subcutaneously daily at a dose of 50 and 100mg/kg for 7 successive days, GPP was also found to decreased blood sugar and hepatic glycoge. In addition, GPP was found to decrease various experimenta hyperglycemias induced by injection of adrenaline, glucose and alloxan. GPP exhibited inhibiting effect on the glycogen enhancement induced by glucose, but strengthening effect on the glycogen decrease induced by adrenaline. When the levels of blood total lipid and liver glycogen were increased by alloxan, GPP was shown to inhibit these changes except its lowering blood sugar. the toxicity of GPP is very low, its LD50 was found to be 1.62$\pm$0.130 g/kg for iv.

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A Longitudinal Study on the Prevalence of Major Adult Chronic Disease in Korean Employees between 2001 and 2010

  • Lee, Gyu-Jang;Kim, Soon-Ki;Kim, Hye-Young;Lee, Chang-Kyou;Lee, Seung-Gwan;Cho, Kyung-Jin
    • Korean Journal of Clinical Laboratory Science
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    • v.44 no.1
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    • pp.7-16
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    • 2012
  • The Korean GDP per capita doubled during the last 10 years. As the GDP increases, Korean health behaviors such as, eating, drinking, smoking, and exercise habits changed as well. Compared to the remarkably advanced diagnostic technologies and therapeutics during the last decade, the leading causes of death in Korea scarcely changed. Among the leading causes of death, cerebrovascular disease, heart disease, diabetes, liver disease and hypertension are closely related to health behaviors. Using the database of medical check-up between 2001 and 2010, the authors performed a longitudinal study for the prevalence rates and the trends of major chronic adult diseases among the 2,721 workers along with their health behavior. Among the diagnostic test items, fasting blood sugar, cholesterol and BMI levels showed steady increase and these three test items all showed linear trends (p<0.001). The average blood sugar and cholesterol levels were near worrying levels. Moreover, the average BMI of males was found to be at the overweight level, intimating the possibility reaching thee Obese Class I level soon if there are no aggressive counter measures. Fasting blood sugar and cholesterol levels were higher in a drinking group as compared to a non-drinking group, and the BMI levels were also higher in the drinking group and the smoking group as compared to the non-drinking and the non-smoking group (p<0.001). Finally, the authors believe that the fasting blood sugar, cholesterol and BMI levels should be designated as target monitoring test items in the medical check-up for Korean employees.

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Factors Influencing Changes in Fasting Blood Sugar Level of Participants in Primary Care Chronic Disease Management Pilot Project using ICT (ICT를 활용한 만성질환관리 시범사업 참여자의 공복혈당수치 변화에 영향을 미치는 요인)

  • Ha, Yu-Hee;Jin, Ki-Nam;Jeong, Jae-Yeon;Choi, Hwa-Young
    • Korea Journal of Hospital Management
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    • v.26 no.1
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    • pp.42-54
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    • 2021
  • The purpose of this study is to analyze that ICT-based primary health care affects clinical changes of participants in the primary care chronic disease management pilot project using ICT medical care. Customized health information data, provided by National Health Insurance Service, was used for the analysis. The study targeted a total of 676 people that participated in primary care chronic disease management pilot project using ICT medical care from 2017 to 2018. Hierarchical regression was used to test three model. First, there were many subjects who used face-to-face consultation and non-face-to-face consultation(messaging), but less than half of patients using non-face-to-face consultation(telephone). Second, after participating in the pilot project, the fasting blood sugar level decreased. Third, the clinical condition of the subjects appeared to be an important factor in controlling blood sugar levels. Finally, patients using the non-face-to-face consultation(messaging) had reduced blood sugar levels after participating in the project. This results imply that non-face-to-face consultation is effective in reducing fasting blood sugar level with hospital intervention, and there are effects of the primary care chronic disease management project using ICT.