• Journal of Preventive Medicine and Public Health
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• v.21 no.1 s.23
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• pp.195-206
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• 1988

Two major issues of the blood bank management are quality assurance and inventory control. Recently, in Korea blood donation has gained popularity increasingly to allow considerable improvement of the quality assurance with respect to blood collection, transportation, storage, component preparation skills and hematological tests. Nevertheless the inventory control, the other issue of blood bank management, has been neglected so far. For the supply of blood by donation barely meets the demand, the blood bank policy on the inventory control has been 'the more the better.' The shortage itself by no means unnecessitate inventory control. In fact, in spite of shortage, no small amount of blood is outdated. The efficient blood inventory control makes it possible to economize the blood usage in the practice of state-of-the-art medical care. For the efficient blood inventory control in Korean hospitals, this tudy is to develop formulae forecasting the standard blood inventory level and suggest a set of policies improving the blood inventory control. For this study informations of $A^+$ whole bloods and packed cells inventory control were collected from a University Hospital and the Central Blood Bank of the Korean Red Cross. Using this informations, 1,461 daily blood inventory records were formulated.48 varieties of blood inventory control environment were identified on the basis of selected combinations of 4 inventory control variables-crossmatch, transfusion, inhospital donation and age of bloods from external supply. In order to decide the optimal blood inventory level for each environment, simulation models were designed to calculate the measures of performance of each environment. After the decision of 48 optimal blood inventory levels, stepwise multiple regression analysis was started where the independent variables were 4 inventory control variables and the dependent variable was optimal inventory level of each environment. Finally the standard blood inventory level decision rule was developed using the backward elimination procedure to select the best regression equation. And the effective alternatives of the issuing policy and crossmatch release period were suggested according to the measures of performance under the condition of the standard blood inventory level. The results of this study' were as follows ; 1. The formulae to calculate the standard blood inventory level($S^*$)was $S^*=2.8617X(d)^{0.9342}$ where d is the mean daily crossmatch(demand) for a blood type. 2. The measures of performace - outdate rate, average period of storage, mean age of transfused bloods, and mean daily available inventory level - were improved after maintenance of the standard inventory level in comparison with the present system. 3. Issuing policy of First In-First Out(FIFO) decreased the outdate rate, while Last In-First Out(LIFO) decreased the mean age of transfused bloods. The decrease of the crossmatch release period reduced the outdate rate and the mean age of transfused bloods.

• IE interfaces
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• v.10 no.1
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• pp.119-134
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• 1997

The management of blood inventory is very important within the medical care system. The efficient management of blood supplies and demands for transfusions is of great economic and social importance to both hospitals and patients. For any blood type, there is a complex interaction among the optimal inventory level, daily demand level, daily supply level, transfusion to crossmatch ratio, crossmatch release period, issuing policy and the age of arriving units that determine the shortage and outdate rate. In this paper, we develop an efficient decision rule for blood inventory management in a hospital blood bank which can support efficient hospital blood inventory management using simulation. The primary use of the efficient decision rule will be to establish minimum cost function which consists of inventory levels, period in inventory, outdate and shortage rate for whole blood and various component inventories for a hospital blood bank or a transfusion service. If the administrator compute the mean daily demand for each blood type, the mean daily supply for each blood type, the length of the crossmatch release period and the average transfusion to crossmatch ratio, then it is possible to apply the efficient decision rule to compute the optimal inventory level, inventory period, outdate and shortage rate. This rule can also be used as a decision support system that allows the blood bank administrator to do sensitivity analysis related to controllable blood inventory parameters.

• Journal of the Korea Society for Simulation
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• v.5 no.1
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• pp.13-27
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• 1996

The management of blood inventory is very important within the medical care system. The efficient management of blood supplies and demands for transfusion is of great economic and social importance to both hospitals and patients. Fro any blood type, there is a complex interaction among the optimal inventory level, daily demand level , daily supply level, transfusion to crossmatch ratio, crossmatch release period, issuing policy and the age of arriving units that determine the shortage and outdate rate. In this paper, we develop an efficient decision rule for blood inventory management in a hospital blood bank which can support efficient hospital blood inventory management using simulation, The primary use of the efficient decision rule will be to establish minimum cost function which consists of inventory levels , period in inventory, outdate and shortage rate for whole blood and various component inventories for a hospital blood bank or a transfusion service, If the adminstrator compute the mean daily demand for each blood type, the mean daily supply for each blood type, the length of the crossmatch release period and the average transfusion to crossmatch ratio , then it is possible to apply the efficient decision rule to compute the optimal inventory level, inventory period , outdate and shortage rate. This rule can also be used as a decision support system that allows the blood bank adminstrator to do sensitivity analysis related to controlled blood inventory parameters.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.3
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• pp.106-116
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• 2021

This paper considers a joint problem for blood inventory planning at hospitals and blood delivery planning from blood centers to hospitals, in order to alleviate the blood service imbalance between big and small hospitals being occurred in practice. The joint problem is to determine delivery timing, delivery quantity, delivery means such as medical drones and legacy blood vehicles, and inventory level to minimize inventory and delivery costs while satisfying hospitals' blood demand over a planning horizon. This problem is formulated as a mixed integer programming model by considering practical constraints such as blood lifespan and drone specification. To solve the problem, this paper employs a Lagrangian relaxation technique and suggests a time efficient Lagrangian heuristic algorithm. The performance of the suggested heuristic is evaluated by conducting computational experiments on randomly-generated problem instances, which are generated by mimicking the real data of Korean Red Cross in Seoul and other reliable sources. The results of computational experiments show that the suggested heuristic obtains near-optimal solutions in a shorter amount of time. In addition, we discuss the effect of changes in the length of blood lifespan, the number of planning periods, the number of hospitals, and drone specifications on the performance of the suggested Lagrangian heuristic.

• Journal of the military operations research society of Korea
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• v.8 no.2
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• pp.37-55
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• 1982

The whole blood inventory control model is developed, shown to provide an accurate representation of actual blood bank operations in Korea. The main difference of the blood bank situations between Korea and the United States is that about 50 percent of all bloods demanded, crossmatched, and held for a particular patient are eventually found not to be required for that patient in case of U.S. while in Korea the crossmatch test is not so significant and almost successful. Accordingly, the model in this paper is focused in seeking the minimum inventory level where neither shortage nor outdating bloods begin to occur, while the Jennings' model, developed in 1970 at MIT OR Center, is the inventory level somewhere between the inventory level 'band' where both shortage and outdating occur.

• Sleep Medicine and Psychophysiology
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• v.5 no.1
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• pp.80-87
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• 1998

Objectives : The purpose of this study was to investigate the relationship among anger expression mode, depression, and blood pressure. Method : Eight hundred sixty-eight male military draftees were asked during the examination procedure to answer Spielberger's Anger Expression Inventory, MMPI Repression Scale, and Beck Depression Inventory(BDI). Blood pressures, weight, and height were also measured. Results : 1) No significant difference was found in the anger-in and anger-out subscales of Spielberger Anger Expression Inventory, MMPI Repression Scale, and BDI between the hypertensives and the normotensives. 2) No significant difference of blood pressure was found between the groups determined by upper and lower 25% of each of the above scales and inventory. 3) The interaction effect of anger-in and anger-out on depression was found to be significant. Conclusion : These findings suggest that there is no relationship among anger-in, anger-out, depression, and blood pressure in young male military draftees. Interestingly, ambivalence of anger expression, i.e. the interaction of anger-in and anger-out, was found to be an important factor related to depression.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.13 no.21
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• pp.133-141
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• 1990

Human blood is a perishable product : it has a legal lifetime of 21 days from collection, during which it can be used for transfusion to a Patient of the same type, and after which it has to be discarded. Therefore, blood must be supplied safely and effectively because it is one of the medical resources which keep humanlife. In this study, the effects of blood issuing policies on average inventory levels and average age of blood at transfusion are determined by simulation applied the theory of absorbing Markov chains. And as a practical study, the daily demand distribution of blood is estimated by using the data of B General Hospital. The distribution estimated follows poisson distribution and the estimator of parameter estimated from the poisson distribution is 0.762. Simulation is done by using the parameter. The most important problem when control blood is the amount of outdata. So we compared random policy with Modified LIFO and Modified FIFO by using outdata. As a results it is shown that Modified LIFO and Modified FIFO by using outdata. As a results it Is shown that Modified LIFO and Modified FIFO present better issuing policy than Random Policy.

• Journal of agricultural medicine and community health
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• v.36 no.3
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• pp.157-166
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• 2011

Objectives: Anxiety and depression are known to be associated with hypertension, and blood pressure can vary spontaneously throughout the day. The aim of this study was to evaluate anxiety, depression and 24-hour ambulatory blood pressure (24-h ambulatory BP) in employees at their worksite. Methods: A total of 107 volunteers among 136 employees at a hotel in Gyeongju, Korea were enrolled in this study between December 2009 and March 2010. The Beck Anxiety Inventory (BAI) and the Beck Depression Inventory (BDI) were used to assess anxiety and depression, respectively. Blood pressure was measured using a 24-h ambulatory BP monitoring system. Results: No significant differences in either BAI or BDI scores were found when hypertensive individuals were compared to normotensive individuals. The frequency of diastolic non-dipper was significantly higher in individuals with depressive symptoms compared to those without (p<0.05). Depression was significantly associated with diastolic non-dipper (OR: 6.85, 95% CI: 1.50-30.01). Conclusions: The results of this study indicate that depression should be considered when deciding upon blood pressure control regimens, and appropriate additive psychotherapy may be beneficial in the treatment of hypertensive patients.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.808-819
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• 2021

Objectives: This study considered the effectiveness of integrative Korean medical treatment for stress-induced hypertensive patients without the use of conventional medication. Methods: A 62-year-old female with stress-induced hypertension (HTN) was hospitalized for 33 days. Her pattern identification was ascendant hyperactivity of liver yang (Ganyangsanghang)-type HTN. Herbal medicine and acupuncture were used for the treatment: Cheonggansoyo-san for 33 days and Chunwangbosim-dan for 15 days, together with acupuncture for 20 minutes twice a day. Blood pressure was checked daily during hospitalization with a digital sphygmomanometer in the brachial artery. Results: After 33 days of treatment, blood pressure decreased. The Handicap Inventory (DHI) scale and Pittsburg Sleep Quality Index (PSQI) scores both decreased. The patient also reported fewer complaints. A five-month follow-up after discharge, with no further treatment, confirmed stable blood pressure. Symptom improvements continued with no significant side effects. Conclusions: This study indicates that Korean medical treatment is effective for stress-induced hypertensive patients.

• Korean Journal of Psychosomatic Medicine
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• v.9 no.2
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• pp.194-202
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• 2001

Objectives : Many studies have shown an association between serum lipid concentrations and psychologic characteristics. However, conflicting results have also been reported. This study was designed to find the relationship between serum lipid levels(cholesterol and triglycerides) and psychologic characteristics(impulsiveness, aggressiveness, depressiveness) in adolescents. Methods : Serum cholesterol concentration, serum triglycerides concentration, complete blood count, electrolytes, liver function test, and blood sugar level were measured by overnight fasting blood sampling and urinalysis was also conducted in 407 high school students. Impulsiveness level was measured by Barratt Impulsiveness Scale(BIS). Aggressiveness level was measured by Buss-Durkee Hostility Inventory(BDHI). Depressiveness level was measured by Beck Depression Inventory(BDI). Serum cholesterol was measured by standard enzymatic assay and serum triglycerides was measured by Boehringer Mannheim method. Results : 1) Low cholesterol group(<15 percentile) were found to have significantly higher BIS score than high cholesterol group(>85 percentile) in female. Female low cholesterol group were also found to have significantly higher motor impulsivity score, a subscale of BIS, than high cholesterol group. 2) High triglycerides group(>85 percentile) were found to have significantly higher BDI score than low triglycerides group(<15 percentile) in male and female separately. Especially, male high triglycerides group were also found to have significantly higher BIS and motor impulsivity score than low triglycerides group. Conclusion : These results support the previous hypothesis that serum lipid levels(cholesterol and triglycerides) affect human psychologic characteristics.