• Title/Summary/Keyword: Blood hemoglobin

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Marked Change in Parameter Level in Patient with Renal Disease

  • Bloh, Anmar Hameed;Obead, Dr. Antesar Rheem;Wahhab, Doaa Nassr
    • Journal of the Korean Chemical Society
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    • v.66 no.2
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    • pp.92-95
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    • 2022
  • Failure Renal is the function of the kidneys to remove waste products and keep them on the periphery. and minerals for the body. Chronic renal failure is a syndrome characterized by a slow, irreversible deterioration of renal function due to the slow destruction of renal parenchyma. Calcium is one of the important minerals that the body contains in the blood and important tissues, and it has an important role in vital processes such as muscle contraction, nerve impulse conduction, the efficiency of heart muscle work, and blood clotting processes. The aim of the study is to study and compare calcium levels in men and women. It includes studying abnormal levels of calcium that cause many diseases, including chronic renal failure, and studying changes associated with renal failure. The method of this study was conducted on patients with chronic renal failure at Murjan Teaching Hospital in Babylon city during the period. The study included a sample of 70 patients (40 males, 30 females) with chronic renal failure, their ages ranged from 30-65, and 60 (30 males, 30 females) healthy without the disease of the same age. The result was a significant decrease in the number of red and white blood cells, hemoglobin concentration, hematocrit and platelets in patients with chronic renal failure, The result has been showed significant level in enzymes activity for transfer of amine group (alanine amino transferase, aspartate amino transferas) and phosphatase alkaline and also concentration of total bilirubin in patient with compare with healthy, Significantly increases, were found in the concentration of urea, uric acid and creatinine, as well as the concentration of calcium and phosphorous ions in the blood serum of patients compared to healthy controls.

Partial least squares regression theory and application in spectroscopic diagnosis of total hemoglobin in whole blood (부분최소제곱회귀(Partial Least Squares Regression) 이론과 분광학적 혈중 헤모글로빈 진단에의 응용)

  • 김선우;김연주;김종원;윤길원
    • The Korean Journal of Applied Statistics
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    • v.10 no.2
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    • pp.227-239
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    • 1997
  • PLSR is a powerful multivariate statistical tool that has been successfully applied to the quantitative analyses of data in spectroscopy, chemistry, and industrial process control. Data in spectorscopy is represented by spectrum matrix measured in many wavelengths. Problems of many kinds of noise in data and itercorrelation between wavelengths are quite common in such data. PLSR utilizes whole data set measured in many wavelengths to the analysis, and handles such problems through data compression method. We investigated the PLSR theory, and applied this method to the data for spectroscopic diagnosis of Total Hemoglobin in whole blood.

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Comparison of the Effects of Internet Diabetes Education by Gender in Type 2 Diabetic Patients (제 2형 당뇨병환자 성별에 따른 인터넷 당뇨 교육 효과 비교)

  • Kim, Hee-Seung;Park, Chai-Soon
    • Women's Health Nursing
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    • v.10 no.2
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    • pp.144-149
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    • 2004
  • Purpose: The purpose of this study was to evaluate whether the effect of Intenet diabetes education varied by gender. Method: An experimental group assessed pre- and post intervention was used to assess the effectiveness of diabetes education by nurses. Forty patients separated into two groups by gender partook in the study. The goal of the intervention was to keep blood glucose concentrations close to normal range. The intervention was applied weekly for 3 months. Participants were requested to input their blood glucose level, diet, and exercise diary everyday at http://www.biodang.com by cellular phone or wire Internet. The researcher sent optimal recommendations to each patient using the short message service of cellular phones and wire Internet. All medication adjustments were communicated to the subjects' doctors. The plasma glucose levels, serum lipids, and care satisfaction were measured before and after the intervention. Result: Glycosylated hemoglobin (HbA1c) decreased 1.6% and 0.8% in male and female patients respectively after 3 months of education. Total cholesterol decreased 37.2mg/dl in male patients but increased 80.5mg/dl in female patients. Conclusion: These findings indicated that Internet diabetes education could improve HbA1c and total cholesterol in male patients.

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The effects of electroacupuncture and laser at Da-zhui and Shen-shu on hematologic changes and blood concentration of endocrine substances in dogs (대추혈(大椎穴) 및 신유혈(腎兪穴)에 대한 전침 레이저자극이 개의 혈액학적 변화와 내분비물질의 혈중농도에 미치는 영향)

  • Cho, Yong-seong;Bae, Chun-sik
    • Korean Journal of Veterinary Research
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    • v.39 no.5
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    • pp.986-994
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    • 1999
  • This study was carried out (a) to investigate the variations of blood chemistry and (b) to examine the secretion trend of endocrine substances in a dog model after electroacupuncture and laser stimulation at different time period(9 to 11a.m. and 6 to 8p.m.). Two acupuncture points ; Da Zhui(GV-14) and Shen Shu(BL-23) were electroacupunctured for 20 minutes with 2Vol, 20Hz and irradiated for 5 minutes with 8,000Hz. Before stimulation and after a lapse of time(10-minutes, 30-minutes and 60-minutes) all dogs were checked the following parameters ; cortisol, ACTH, RBC, hemoglobin, hematocrit, WBC, Ca, P, SGPT, SGOT and creatinine. The results were as follow : The levels of cortisol and ACTH have been increased 10 minutes after the stimulation of the electroacupuncture and laser. The higher levels of cortisol and ACTH have been decreased to keep the normal levels from 30 minutes after the stimulation of the electroacupuncture and laser. The RBC, hemoglobin, hematocrit and WBC showed the physiological phenomena in the electroacupuncture and laser stimulation. In sero chemical analysis, calcium, phosphate, SGOT, SGPT and creatinine levels were within normal physiological ranges.

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Effects of Ammonia Concentration on Histological and Physiological Status in Black Seabream (Acanthopagrus schlegeli)

  • KWON Joon Yeong;CHANG Young Jin
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.6
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    • pp.828-836
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    • 1996
  • The histological changes of gill, liver, spleen and muscle, and respiration and blood variables and liver glycogen content were examined in black seabream, Acanthopagrus schlegeli. Fish were exposed to a high level of total ammonia nitrogen (10.4 mg/l) and recovered from exposure $(0.4{\pm}0.2mg/l)$ in a closed recirculating seawater system. In the process of exposure, mortality was $9\%$, and hyperplasia, necrosis or inflammation appeared in all tissues except for muscle. Oxygen consumption was decreased by $49\%$, and red blood cell (RBC) number, hematocrit and hemoglobin concentration were significantly decreased, while plasma glucose contents, activities of glutamate-oxaloacetate transaminase (GOT) and glutamate-pyruvate transaminase (GPT) increased. Liver glycogen content significantly increased from $6.6\%\;to\;10.4\%$. A large amount of hemosiderin was observed in the splenic tissue. During the recovery period, RBC number, hematocrit, hemoglobin concentration, GOT and GPT activities were returned to the normal status. Histological status of liver tissue was returned to the normal, but liver glycogen content was not recovered. During the recovery period, spleen melanin-macrophages temporarily increased, but subsequently decreased to the normal status.

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The Effect of Electro-acupuncture at ST36 on Carbon Tetrachloride-induced Chronic Hepatic Damage in Rats (족삼리 전침자극이 Carbon Tetrachloride 장기투여로 유발된 흰쥐의 만성 간손상에 미치는 영향)

  • Kim, Byung-Soo;Lee, Hyun-Suk;Yim, Yun-Kyoung
    • Korean Journal of Acupuncture
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    • v.32 no.3
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    • pp.90-98
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    • 2015
  • Objectives : The purpose of this study is to investigate the effect of electro-acupuncture(EA) at ST36 on $CCl_4{^-}$ induced chronic hepatic damage in rats. Methods : The authors performed several experimental items, including measurements of liver index, hematological analysis for WBC, lymphocytes, neutrophils, monocytes, hemoglobin, and biochemical assays for ALT, AST, ALP in serum, and histological analysis of liver tissue. Results : Liver index(liver weight/body weight), the levels of WBC, Neutrophils and Monocytes in blood, the levels of ALT, AST and ALP in serum which were increased by $CCl_4{^-}$ intoxication were reduced significantly by EA at ST36. The levels of lymphocyte and hemoglobin in blood which were decreased by $CCl_4{^-}$ intoxication were significantly increased by EA at ST36. Conclusions : EA at ST36 has a hepatoprotective effect on chronic hepatic damage in $CCl_4{^-}$ intoxicated rats.

Blood Glucose Lowering Activity and Mechanism of Sangbackpitang (SBPT) in db/db Mouse (db/db 마우스에서 상백피탕의 혈당강하 활성 및 기전연구)

  • 이성현;안세영;두호경;정성현
    • YAKHAK HOEJI
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    • v.43 no.6
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    • pp.818-826
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    • 1999
  • Antidiabetic activity and mechanism of Sangbackpitang (SBPT) was examined in db/db mice, which is a spontaneously hyperglycemic, hyperinsulinemic and obese animal model. SBPT and acarbose were administered orally for 4 weeks. Fasting and non-fasting serum glucose, glycated hemoglobin and triglyceride were all reduced when compared between db/db control group and SBPT treated group. At 12th week after birth, SBPT increased an insulin secretion although statistic significance was not seen. Total activities of sucrase, maltase and lactase in SBPT treated group were all decreased when compared to db/db control. On the other hand, sucrase and maltase activities in acarbose treated groups were increased. Effect of SBPT on mRNA expression of glucose transporter(GLUT-4) was also examined. Quantitation of glucose transporter was performed by RT-PCR and in vitro transcription with co-amplification of rat-action gene as an internal standard. Muscular GLUT-4 mRNA expression in SBPT treated group was increased significantly. These results may suggest that SBPT lowered blood glucose ascribing to inhibition of glycosidase-catalyzed reaction and upregulation of muscular GLUT-4 mRNA expression.

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Effect of Telephone Follow-up on Blood Glucose Improvement of Diabetes Mellitus Patients with Depressive Symptoms (전화추후관리가 우울성향을 가진 당뇨병 환자의 혈당개선에 미치는 효과)

  • Song, Min-Sun;Kim, Hee-Seung;Lee, Dong-Han
    • Journal of Korean Biological Nursing Science
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    • v.8 no.2
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    • pp.29-39
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    • 2006
  • The aim of this study was to examine the effect of telephone follow-up on glycemic control, lipid profiles. and treatment method in diabetic patients with depressive symptoms over one year follow-up period. Twenty-two diabetic patients attended the structured diabetes education program between March 2004 and February 2005 and completed a questionnaire using the Beck Depression Inventory(BDI) to measure depressive symptoms. The patients showed depressive symptoms with the criterion being a BDI score at least 16. The intervention was applied to the telephone follow-up for one year. Data were analyzed using Wilcoxon signed rank test and McNemar test. The patients decreased their mean glycosylated hemoglobin(HbAlc) levels by 1.9%(p=0.001). There was a significant mean change in the fasting blood sugar(FBS) level, with a mean change of -61mg/$d{\ell}$(p=0.008). These findings indicated that the telephone follow-up may be effective in the HbAlc and FBS control.

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Influence of Other Blood Components in Predicting Glucose Concentration using Design of Experiment (실험계획 법에 의한 혈중 글루코즈 측정 시 타 성분의 영향 분석)

  • 김연주;윤길원;전계진
    • Journal of Biomedical Engineering Research
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    • v.22 no.6
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    • pp.497-502
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    • 2001
  • Influence of other blond components on measuring glucose concentration was analyzed B)food phantom containing five major components was made. The prediction model was developed based on the measurement of absorption spectra including the first overtone glucose band, i.e.. 1500 ∼ 1850 nm. The concentrations were Predicted using the Partial least squares regression. Factor analysis based on Design of Experiment was Performed to study the influence of other components in predicting glucose concentration. Triglyceride does not influence. Albumin and globulin haute minor effects. However, hemoglobin showed substantial response and the compensation of hemoglobin concentration appears to be required for the model of glucose measurement.

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Study on the hemodynamics in the cows diseased with mastitis (유방염에 이환된 젖소에 있어서 혈액 동태학에 관한 연구)

  • Son, Sung-gi;Heo, Jung-ho;Lee, Ju-hong;Kim, Chung-hui;Kim, Gon-sup;Kim, Jong-shu
    • Korean Journal of Veterinary Research
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    • v.35 no.3
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    • pp.595-601
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    • 1995
  • Hemodynamic values were assessed in the cows diseased with mastitis. Hemodynamic testes were performed for white blood cell(WBC), red blood cell(RBC), packed cell volume(PCV), hemoglobin concentration, monocyte, eosinophil, neutrophil, lymphocyte, prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen, platelet concentrations, antithrombin-III and plasminogen activities. Significant alterations were observed in the mean values of most analytes. The numbers of monocytes, eosinophil, and neutrophil, and prothrombin time were increased while the number of lymphocyte, activated partial thromboplastin time, thrombin time, fibrinogen concentration, plasminogen activity and platelet concentration were decreased. The number of RBC, PCV, hemoglobin and antithrombin-III activity were unchanged compared with normal mean values. These data indicated that activation of hemodynamic mechanisms was initiated either directly by the endotoxin-releasing or indirectly by the inflammatory mediators released by response to etiologic agents. We suspected that the changes of hemodynamic values in the cows diseased with mastitis were very similar to those of experimental endotoxin-induced mastitis.

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