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http://dx.doi.org/10.14406/acu.2015.016

The Effect of Electro-acupuncture at ST36 on Carbon Tetrachloride-induced Chronic Hepatic Damage in Rats  

Kim, Byung-Soo (Department of Meridian and Acupoint, College of Korean Medicine, Daejeon University)
Lee, Hyun-Suk (Department of Meridian and Acupoint, College of Korean Medicine, Daejeon University)
Yim, Yun-Kyoung (Department of Meridian and Acupoint, College of Korean Medicine, Daejeon University)
Publication Information
Korean Journal of Acupuncture / v.32, no.3, 2015 , pp. 90-98 More about this Journal
Abstract
Objectives : The purpose of this study is to investigate the effect of electro-acupuncture(EA) at ST36 on $CCl_4{^-}$ induced chronic hepatic damage in rats. Methods : The authors performed several experimental items, including measurements of liver index, hematological analysis for WBC, lymphocytes, neutrophils, monocytes, hemoglobin, and biochemical assays for ALT, AST, ALP in serum, and histological analysis of liver tissue. Results : Liver index(liver weight/body weight), the levels of WBC, Neutrophils and Monocytes in blood, the levels of ALT, AST and ALP in serum which were increased by $CCl_4{^-}$ intoxication were reduced significantly by EA at ST36. The levels of lymphocyte and hemoglobin in blood which were decreased by $CCl_4{^-}$ intoxication were significantly increased by EA at ST36. Conclusions : EA at ST36 has a hepatoprotective effect on chronic hepatic damage in $CCl_4{^-}$ intoxicated rats.
Keywords
Electro-acupuncture; ST36; CCl4; liver demage;
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Times Cited By KSCI : 4  (Citation Analysis)
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