• Title/Summary/Keyword: Blood gas analysis

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A Clinical Study on Myocardial Metabolism in Warm Versus Cold Continuous Blood Cardioplegia (냉혈 및 온혈 심정지액의 연속관류시 심근대사에 대한 임상연구)

  • 백완기
    • Journal of Chest Surgery
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    • v.27 no.6
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    • pp.427-434
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    • 1994
  • A clinical study was designed to evaluate myocardial metabolism during continuous cold blood cardioplegia [Group A, n=10] in comparison with continuous warm blood cardioplegia [Group B, n=10], in a prospective randomized manner. Myocardial metabolism was assessed in two ways: either by collecting blood from coronary sinus before and after cardiopulmonary bypass or by collecting blood from cardioplegic affluent and effluent simultaneously at the beginning and at the end of cardioplegia. The former samples were assayed for gas analysis, lactic acid and cardiac enzyme [CK, LDH, SGOT] and the latter for gas analysis and lactic acid as a maker of anaerobic metabolism. The results were as follows. 1] Myocardial metabolism was shown to be continued in the state of cardioplegia at lower temperature as evidenced by high oxygen extraction of cardioplegic solution in Group A. 2] Anaerobic metabolism occurring at lower temperature in spite of continuous cold blood cardioplegia can be significantly reduced by continuous perfusion of normothermic blood cardioplegics as evidenced by significant reduction of lactate production in Group B [p〈0.05]. 3] Better myocardial protection can be achieved by employing continuous warm blood cardioplegia as evidenced by less cardiac enzyme release in Group B after cardiopulmonary bypass.

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Relationship between the values of blood parameters and physical status in Korean native calves with diarrhea

  • Lee, Sung-Hwan;Choi, Eun Wha;Kim, Doo
    • Journal of Veterinary Science
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    • v.21 no.2
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    • pp.17.1-17.11
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    • 2020
  • Dehydration, electrolyte disturbance, and acid-base imbalance are the most significant consequences of diarrhea in calves. We aimed to determine blood gas, hematological, electrolyte, and biochemical values and investigate the relationship between the physical status and blood parameters in Korean native calves (KNCs) with diarrhea. One hundred eighty KNCs with diarrhea (age < 75 days) were investigated. Blood samples were collected from the external jugular vein and analyzed using a portable clinical blood gas analyzer. The measured parameters were statistically compared according to the status of physical activity, dehydration, or prognosis. The mean values of parameters in the Calves with diarrhea showed metabolic acidosis, hyponatremia, and azotemia. The mean values of potassium, chloride, hematocrit, and hemoglobin were in the upper limit of their reference ranges. More than 75% of the calves had metabolic acidosis caused by bicarbonate loss, and 63.6% had high blood urea nitrogen (BUN) values. Moreover, BUN showed the highest correlation with the physical activity status and dehydration. pH, base excess of the extracellular fluid (BE), anion gap, potassium, hematocrit, bicarbonate, and hemoglobin were closely correlated with physical deterioration and dehydration (p < 0.001). BUN, pH, BE, and anion gap were closely correlated with physical deterioration and dehydration. These correlations between clinical symptoms and blood gas parameters can be clinically relevant in predicting the status of parameters according to clinical symptoms.

A CLINICAL STUDY ON PULMONARY FUNCTION AFTER INTERMAXILLARY FIXATION (악간고정이 호흡기능에 미치는 영향에 대한 임상적 연구)

  • Kim, Chul-Hwan;Kim, Mi-Suk
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.25 no.4
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    • pp.361-366
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    • 1999
  • Intermaxillary fixation is routine procedure to oral and maxillofacial area in jaw bone fracture, surgical correction of jaw deformity, osseus reconstruction of jaw. After transoral surgery, accompanied by intermaxillary fixation, dysphagia or airway obstruction may be followed due to blood clot, vomitus, or laryngeal spasm resulting from irritation by blood or secretions. Lingual or pharyngeal edema is other contributing factors of airway obstruction. In addition, intermaxillary fixation itself may cause obstruction of airway. In this study, pulmonary function test and arterial blood gas analysis were evaluated before and after intermaxillary fixation in 30 patients suffered from mandibular fractures. Comparative analysis was performed by estimated values. The results were as followed. 1. The spirometric values of FEV1, FEV1/FVC and FEF25-75% without intermaxillary fixation were reduced from 97.57%, 85.1%, 98.3,% to 71.7%, 66.5%, 61.2% with intermaxillary fixation, indicating the presence of obstructive pulmonary impairment. 2. Spirometric value of MVV, as the most influencing value of sensitive to extrapulmonary factors, was changed from 84.5% to 46.48%. 3. After intermaxillary fixation, the spirometric value of FVC, as indicator of restrictive pattern of pulmonary function, was not reduced significantly as measured from 94.47% to 89.97%. 4. $O_2$ saturation of arterial blood gas analysis without intermaxillary fixation was 97.86%. While intermaxillary fixation, $O_2$ saturation was 97.47%. The results indicate that careful airway management is mandatory undergoing intermaxillary fixation of various oral and maxillofacial surgery.

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Implementation on the Portable Blood Gas Analyzer (휴대형 혈액가스 분석시스템의 구현)

  • Kang S.C.;Jeong D.U.;Bae J.W.;Shon J.M.;Shim Y.B.;Jeon G.R.
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2006.05a
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    • pp.1032-1036
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    • 2006
  • In this study, we implement the potable blood gas analyzer measuring pH, $pCO_2\;and\;pO_2$ of the arterial blood. The implemented system by this study is divided into hardware and software part and also the hardware portion is parted by mechanism and electronic circuit mit. The system program is composed of operating, washing, correcting and measuring program. And to correct the system, two-point calibration method is used, one-point calibration method is also added for more accuracy, and system program is coded. For verifying the implemented system, We examine to response property of each electrode. And evaluate accuracy of the system using standard reagent and was construed as statistical.

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A Study on MDA Analysis & blood chemical test for Mouse which were exposed HF Gases from Fire (화재로 인한 불화수소(HF)가스에 노출된 마우스의 혈액생화학분석 및 MDA분석을 통한 세포손상에 관한 연구)

  • Cho, Nam-Wook;Oh, Eun-Ha
    • Journal of the Korean Institute of Gas
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    • v.17 no.6
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    • pp.58-66
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    • 2013
  • Among the risks which can be faced with fire, combustion toxicity is a significant influence on the survival. Fire toxicity researches have been limited generally on the lethal aspects. In this study, HF gas which can be generated from fire, and also found in general industrial site was used for analysis. Blood analysis and biochemistry analysis performed to find internal demage of experimental animals which were used for measuring average activity stopping time from Animal test(KS F2271: Gas hazard test). In addition, Using the malondialdehyde analysis, indicators of oxidative damage, we had quantitative analysis to target lymphocyte for measuring the oxidative damage caused by toxic substances.

Serum Fructosamine for Assessment of Glycemic Control in a Cat with Diabetic Ketoacidosis (고양이에서 혈중 Fructosamine을 이용한 인슐린 의존성 당뇨병성 케톤산 혈증 치료 예)

  • 권은주;권영삼;오태호;장광호;장인호
    • Journal of Veterinary Clinics
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    • v.18 no.1
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    • pp.74-77
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    • 2001
  • A ten-year-old, male cat presented with recent loss of body weight, depression, vomiting, anorexia, polydipsia, and polyuria. General physical findings included depression, weakness, severe dehydration and a strong acetone odor on the breath. A complete blood count and serum biochemical profiles were leukocytosis, hyperglycemia (286 mg/dl), hypokalemia (2.6 mEq/L), hyponatremia, and high serum fructosamine (600 $\mu$mol/L). In blood gas analysis the cat had acidosis (pH 7.127, p$CO_2$26.7 mmHg). In urinalysis glycosuria and ketouria were appeared. On the basis of clinical signs, serum chemistry, blood gas analysis and urinalysis, diabetic ketoacidosis was diagnosed. Treatment included subcutaneous administration of protamine zinc insulin (0.75 U/head) and intravenous administration of 0.9% saline. Potassium phosphate and sodium bicarbonate was added to the fluids. Serum fructosamine for assessment of glycemic control was measured on occasion calls. On day 296, the patient improved clinically and did not experience any problems resulting from diabetic ketoacidosis.

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Quantitative Analysis of Prussic Acid by "Micro-Diffusion Analsis." II Determination of Prussic Acid in Human Blood (미량확산분석법에 의한 청산의 정량법 (제2보) 혈액중(CN-Met Hb)청산의 정량)

  • 심상혁;서정현
    • YAKHAK HOEJI
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    • v.4 no.1
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    • pp.47-49
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    • 1959
  • Another application of the new quantitative analytical method of prussic acid by "Microdiffusion analysis" for the determination of prussic acid in human blood was studied. The blood containing potassium cyanide was dropped in outer room of unit, and then N-sulfuric acid was added. The liberated HCN gas was absorbed into nickel sulfate solution of inner room, afterward, absorbed prussic acid was determined with EDTA by residual titration. The result was coincided with the result of Liebig Denigs' method at ordinary temperature.

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Development of Automatic Data Transmitting System of Arterial Blood Gas Results via Local Area Network( LAN) (LAN을 이용한 혈액가스 검사결과 전송시스템)

  • 김남현;김원기
    • Journal of Biomedical Engineering Research
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    • v.14 no.4
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    • pp.327-332
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    • 1993
  • Automatic transmission of data from the blood analyzer to the request site is one of the most important part in hospital computerization. We have developed a system that transmits data from the arterial blood gas analyzer to the request site automatically In this system HOST computer, FILE server,'LAN(Local Area Network) , 3270 Emulator and bfulti-port card are integrated with 3 blood gas analyzers(NOVA Inc., USA) which are connected to a single multi-port card in a personal computer. When specimen are collected from tramp)inly sites, they are transferee to the laboratory In the Yonsei Cardiovascular Center After analysis, the result is transmitted to the personal computer via serial commnunication between machine and multi-port card using interrupt method. Then, the patient's information (Name, Patient ID No., etc.) is obtained from the HOST computer througth the emulator. The combined data (patient information & lab data) is transmitted to each request site via LAN automatically These results are stored in the File Server for one year and they can be reviewed anytime. Also, it could be used for the various statistics and the flow chart for clinical research. Additionally, we found thal this system reduces the personal labor.

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Bleeding Efficiency and Meat Oxidative Stability and Microbiological Quality of New Zealand White Rabbits Subjected to Halal Slaughter without Stunning and Gas Stun-killing

  • Nakyinsige, K.;Fatimah, A.B.;Aghwan, Z.A.;Zulkifli, I.;Goh, Y.M.;Sazili, A.Q.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.3
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    • pp.406-413
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    • 2014
  • A study was conducted to compare the effect of halal slaughter without stunning and gas stun killing followed by bleeding on residual blood content and storage stability of rabbit meat. Eighty male New Zealand white rabbits were divided into two groups of 40 animals each and subjected to either halal slaughter without stunning (HS) or gas stun-kill (GK). The volume of blood lost during exsanguination was measured. Residual blood was further quantified by determination of haemoglobin content in Longissimus lumborum (LL) muscle. Storage stability of the meat was evaluated by microbiological analysis and measuring lipid oxidation in terms of thiobarbituric acid reactive substances (TBARS). HS resulted in significantly higher blood loss than GK. HS had significantly lower residual haemoglobin in LL muscle compared to GK. Slaughter method had no effect on rabbit meat lipid oxidation at 0, 1, and 3 d postmortem. However, at 5 and 8 days of storage at $4^{\circ}C$, significant differences (p<0.05) were found, with meat from the GK group exhibiting significantly higher levels of MDA than that from HS. At day 3, greater growth of Pseudomonas aeroginosa and E. coli were observed in the GK group (p<0.05) with B. thermosphacta and total aerobic counts remained unaffected by slaughter method. At days 5 and 7 postmortem, bacterial counts for all tested microbes were affected by slaughter method, with GK exhibiting significantly higher growth than HS. It can be concluded that slaughter method can affect keeping quality of rabbit meat, and HS may be a favourable option compared to GK due to high bleed out.

The Relationship between Blood Transfusion and Mortality in Trauma Patients (외상환자에서 수혈과 사망의 연관성)

  • Choi, Se Young;Lee, Jun Ho;Choi, Young Cheol
    • Journal of Trauma and Injury
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    • v.21 no.2
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    • pp.108-114
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    • 2008
  • Purpose: Using a propensity analysis, a recent study reported that blood transfusion might not be an independent predictor of mortality in critically ill patients, which contradicted the results of earlier studies. This study aims to reveal whether or not blood transfusion is an independent predictor of mortality in trauma patients. Methods: A total of three hundred fifty consecutive trauma patients who were admitted to our emergency center from January 2004 to October 2005 and who underwent an arterial blood gas analysis and a venous blood analysis were included in this study. Their medical records were collected prospectively and retrospectively. Using a multivariate logistic analysis, data on the total population and on the propensity-score -matched population were retrospectively analyzed for association with mortality. Results: Of the three hundred fifty patients, one hundred twenty-nine (36.9%) received a blood transfusion. These patients were older (mean age: 48 vs. 44 years; p=0.019) and had a higher mortality rate (27.9% vs. 7.7%; p<0.001). In the total population, the multivariate analysis revealed that the Glasgow coma scale score, the systolic blood pressure, bicarbonate, the need for respiratory support, past medical history of heart disease, the amount of blood transfusion for 24 hours, and hemoglobin were associated with mortality. In thirty-seven pairs of patients matched with a propensity score, potassium, new injury severity score, amount of blood transfusion for 24 hours, and pulse rate were associated with mortality in the multivariate analysis. Therefore, blood transfusion was a significant independent predictor of mortality in trauma patients. Conclusion: Blood transfusion was revealed to be a significant independent predictor of mortality in the total population of trauma patients and in the propensity-score-matched population.