• The Korea Journal of Herbology
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• v.35 no.5
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• pp.41-46
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• 2020

Objectives : According to 2013 statistics, the primary infertility rate is 13.5%. The current situation is much worse than that reported, so it is even emerging as a social problem. The purpose of this study is to analyze the 5 cases of successful infertility treatment with herbal treatment and to give hope to the infertile couple to become pregnant and to suggest the possibility of herbal treatment in infertility treatment. Methods : We administered Jokyungjongok-tang gamibang as a herbal medicine and treated with acupuncture, moxibustion. Treatment was done once or twice a week. The herbal medicines were taken 30 minutes after meals and 3 times a day. While taking the herbal medicine, they were prohibited from eating flour, pork, liquor, tobacco and coffee. Patient status was assessed by consultation through pulse, tongue and abdominal diagnosis. The diagnosis of pregnancy was confirmed by ultrasonography at hospitals and the success of the treatment was judged based on healthy birth. Results : Patients had common features, such as lower abdominal pain, menstrual cramps, and blood clots during menstruation. Herbal medicine combined with acupuncture, moxibustion improved patients' overall fatigue and reduced the body's coldness. Since then, the dysmenorrhea and blood clots have decreased, and the digestion condition has improved. Therefore they became pregnant and gave birth to a healthy baby. Conclusion : Jokyungjongok-tang gamibang was effective in improving the body's coldness and uterine condition and was successful in pregnancy and helped to give birth to a healthy baby.

• Journal of Sasang Constitutional Medicine
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• v.34 no.2
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• pp.75-83
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• 2022

Objectives The aim of this study is to report the improvement in Taeeumin's dryness-heat symptom of a 54-year-old man diagnosed with type-II diabetes mellitus after treated by herbal medicine. Methods The Taeeumin patient took Yuldahansotang-gamibang for 9 months to manage Taeeumin's dryness-heat symptom. We examined the changes of Body Mass Index(BMI), Fating Blood Sugar(FBS), Hemoglobin A1c(HbA1c), and ketouria. Results Type-II diabetes mellitus symptoms in the patient with Taeeumin's dryness-heat symptom were thirst, fatigue, and increased body weight. All numerical levels for blood sugar, HbA1c, and ketouria were reduced after taking Yuldahansotang-gamibang. Conclusions The treatment of the patient with Taeeumin's dryness-heat symptom and type-II diabetes mellitus with Yuldahansotang-gamibang was efficient, and further research is needed to prove the effect of Yuldahansotang-gamibang for treating such patients.

• Journal of Medicine and Life Science
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• v.19 no.2
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• pp.74-77
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• 2022

We present a fatal case of cerebral arterial thrombosis after corona virus disease 19 (COVID-19) vaccination with ChAdOx1 nCOV-19. The deceased was a 63-year-old woman with no relevant medical history. She presented symptoms of nausea, fatigue, and headache immediately after vaccination. Ten days after vaccination, she suddenly started vomiting and developed high blood pressure. The patient eventually died 23 days after vaccination. Autopsy findings showed that the cerebral arteries and internal carotid arteries were fully enlarged and were compacted with thrombi. The brain stem showed ischemic necrosis, and extravasation from this necrotic lesion led to focal subarachnoid hemorrhage around the brain stem where large blood clots still remained. No aneurysms or atherosclerotic changes were found in these arteries. We note the following three facts. Firstly, all symptoms occurred immediately after vaccination; secondly, the main cause of death was consistent with known side effects of the vaccine; and lastly, the mechanism of thrombus formation in this case goes beyond the general category of thrombogenesis known so far. While the authors know that this case does not fall into known categories of vaccine side effects, we presenting this case to demonstrate that a comprehensive review of various possibilities related to vaccine side effects is needed to establish a COVID-19 defense system.

• Journal of Sasang Constitutional Medicine
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• v.35 no.4
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• pp.96-104
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• 2023

Objectives The purpose of this study was to report the clinical effect on a 54-year-old diabetes patient, categorized into taeeumin exterior disease, after taking herbal medicine. Methods The patient was diagnosed as taeeumin's esophagus-cold pattern and type 2 diabetes symptoms in taeeumin patient were indigestion, fatigue, and headache. We assessed the changes of fasting blood sugar(FBS), hemoglobin A1c(HbA1c), and total cholesterol. Results and Conclusions FBS, HbA1c, and total cholesterol reduced after treated by Jowiseungchungtang-gamibang three times per day for 5 months. These results show that treating a diabetic patient, accompanied by esophagus-cold symptoms, with Jowiseungchungtang-gamibang particularly improves high blood glucose after orthopedic surgery in practicing healthy eating habits.

• The Journal of Internal Korean Medicine
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• v.45 no.3
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• pp.444-455
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• 2024

Objectives: This study aimed to report a case of alcoholic hepatitis with megaloblastic anemia that improved with Korean medicine treatment. Methods: A 27-year-old woman with alcoholic hepatitis and megaloblastic anemia was treated with herbal medicine, acupuncture, and moxibustion. The responses before and after treatment were evaluated using blood tests, ultrasound imaging, the Checklist Individual Strength (CIS), and the numerical rating scale (NRS). Results: Post-treatment, blood tests showed improved liver function test, lipid test, and anemia work-up. Ultrasound imaging showed improvement in the superoinferior diameter of right lobe, from 13.02 to 11.09, and the fatty liver improved. The CIS score decreased from 107 to 55. Fatigue diminished from NRS 10 to NRS 3, and dizziness dropped from NRS 5 to NRS 1. The abdominal distension slightly decreased, from NRS 7 to NRS 5. Conclusion: Korean medicine treatment might be effective for treating alcoholic hepatitis with megaloblastic anemia.

• Journal of Preventive Medicine and Public Health
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• v.24 no.2 s.34
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• pp.181-194
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• 1991

This study intended to obtain an useful information on the prevalence of subjective symptoms, and to clarify the interrelationships between blood lead and lead related symptoms in low level lead exposure. The 93 male workers exposed to lead and 56 male nonexposed workers were examined for their blood lead(PBB), Zinc-protoporphy(ZPP), hemoglobin(HB) and personnal history, and completed 15 questionnaires related to symptoms of lead absorption : also measured lead concentration in air (PBA) in the workplace. The results obtained were as follows ; 1. The means of blood lead (PBB), blood ZPP and hemoglobin (HB) among workers exposed to lead were $26.1{\pm}8.8{\mu}g/dl,\;28.3{\pm}26.0{\mu}g/dl$ and $16.2{\pm}1.2g/dl$ : whereas those of nonexposed workers were $18.7{\pm}5.1{\mu}g/dl,\;20.6{\pm}8.7{\mu}g/dl$ and $17.3{\pm}1.1g/dl$. The means of above three indicies between two groups showed significant difference statistically (p<0.05). 2. The means of blood lead (PBB), blood ZPP and hemoglobin of workers exposed .to different lead concentration in air were as follows : When it was below $25{\mu}g/m^3$, the indices were $24.7{\pm}79,\;26.1{\pm}26.8{\mu}g/dl\;and\;16.4{\pm}1.1g/dl$ respectively : These indices were $27.1{\pm}8.5,\;23.9{\pm}10.92{\mu}g/dl\;and\;16.2{\pm}1.3g/dl$ when the lead concentration in air was $25{\sim}50{\mu}g/m^3$ : and they were $3.4{\pm}9.3,\;42.3{\pm}31.3{\mu}g/dl\;and\;15.5{\pm}1.2g/dl$ when the concentration of lead was above $50{\mu}g/m^3$. Although there were statistical difference in blood lead and hemoglobin among three different lead concentration in air, there was no statistical difference of blood ZPP among the three groups with different exposure levels (p>0.05). 3. The most frequent by complained symptom was 'Generalized weakness and fatigue', and fewest symptom was 'Intermittent pains in abdomen' 4. Only two symptoms out of fifteen symptoms checked by themselves revealed significant difference between exposed and nonexposed groups. These were 'Intermittent pains of abdomen' and 'Joint pain or arthralgia' (p<0.05), No positive correlation was found between the levels of blood lead and symptom groups categorized as gastrointestinal, neuromuscular and constitutional symptoms, 5. Blood lead (r=0.3995) and ZPP (r=0.2837) showed statistically significant correlation with mean lead concentration in air, whereas correlations were not demonstrated between blood lead and lead related symptoms or blood ZPP and lead related symptoms. 6. Blood lead (PBB) and ZPP showed association (r=0.2466) and the equation PBB=23.75+0.0842 ZPP was derived. 7. On stepwise multiple regression, using blood lead level as a dependent variable and ZPP, hemoglobin (HB), age, work duration (WD) and symptom prevalence as a independent variables, only ZPP significantly contributed a lot to blood lead level. 8. While the ZPP measurement was found to be a good indicator in evaluating health effect of lead absorption in low level lead exposure, lead related symptoms were not sensitive enough to evaluate of lead absorption in low level exposure.

• Journal of Embryo Transfer
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• v.23 no.4
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• pp.283-289
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• 2008

Lepidium meyenii, known as Maca, is traditionally employed in the Andean region for its supposed properties to improve energy and fertility. In the present study, we investigated the effects of gelatinized and fermented Maca on improvement of physical stamina and epididymal sperm counts, and on blood biochemical parameters related to fatigue and tissue injury: creatine phosphokinase, aspartate transaminase, lactate dehydrogenase, blood urea nitrogen, glucose, total cholesterol and total proteins. Adult male mice was divided at random into two main groups (resting and excercise groups). The excercise group was separated into three subgroups (exercise only, exercise with gelatinized Maca and fermented Maca-treatment groups). Gelatinized or fermented Maca (800 mg/kg) were orally administered for 30 days. All animals in exercise groups were subjected to daily 30-min swimming for 28 days 30 min after Maca treatment. Daily exercise decreased the body weight gain, and fermented Maca further attenuated the body weight increase. Gelatinized and fermented Maca significantly increased the maximum swimming time on 14 and 28 days of treatment (p<0.05), respectively, suggestive of a long-term stamina-enhancing effect of fermented Maca. Both Maca fully or significantly recovered blood parameters of energy as well as muscular and hepatocytic injuries changed by repeated exercise and maximum swimming performance (p<0.01). Moreover, gelatinized and fermented Maca increased epididymal sperm counts 22.0% and 32.0%, respectively. In conclusion, the results indicate potential benefits of Maca for improving both physical stamina by minimizing muscular and hepatic damage and preserving energy during swimming exercise and male reproductive function by increasing epididymal sperm counts.

• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.836-843
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• 2005

Objective : Liver cirrhosis is a disease of the liver in which normal cells are replated by scar tissue. Chronic liver disease and liver cirrhosis are the foutth ranked causes of death in Korea. However, clinical data on liver cirrhosis is not accumulated in oriental medicine. Therefore, clinical characteristics of 33 liver patients admitted to Hana Oriental Hospital from May 2004 to May 2005 were studied. Methods : Clinical characteristics of liver cirrhosis, such sex, age, causes, Child-Pugh class, chief complain, abdomen ultrasonography, disease duration, past history, blood test and urinalysis were reviewed. Results : The results of this study were as follows: 1 The distribution of sex and age in our study is similar to already reported statistics. 2. Hepatitis B and alcohol are the major factors to cause the liver cirrhosis. Diabetes and hypertention contribute more to cause than they have in previous histories. 3. Major symptoms are following: fatigue 87.9%, ascites 84.8%, jaundice 78.8%, leg edema 72.7%, dyspepsia 45.5%. 4. Most liver cirrhosis patients have pancytopenia. Standard Deviation accentuates the big differences between total bilirubin and serum amonia. 5. In urinalysis, Urobilinogen 19 patients (57.6%), bilirubin 12 patients (36.4%), blood 15 patients (45.5%) are positive. 11 cases of 15 in blood positive results scored $3{\sim}4+$. Contusions : In oriental medicine, it will be necessary to research and develop oriental medical therapies for liver disease including liver cirrhosis.

• Journal of Oriental Neuropsychiatry
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• v.11 no.2
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• pp.63-78
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• 2000

Headache is one of the most common medical complaints. It is not so easy to manage headache. especially if it is chronic although it seldom cause serious problem. There are many psychological factor known to induce, maintain an aggravate symptom in patients with chronic headache. The purpose of this study is to investigate clinical characteristics with ABR-2000 was carried out for 57 patients who had been suffered from headache for 6 months from march to August 2000.The results were as follows:1. According to the statics, on the whole woman's rate was higher than man's, and the mean duration of the headache was 8.06 years.2. Common associated symptoms were nausea. dyspepsia, dizziness, palpitation, fatigue, depression, etc.3. According to oriental medical differentiation of symptoms and signs, the rate of stagnation of the liver-qi's fire-transmission(肝變化火), deficiency of blood(血虛) and plegm syncope (痰厥), these three types were hghest.4. Result of analyzing ABR-2000 is that the rate of low response is higher than high response's on each item. But result of Graph A is that the rate of high response in higher than that of low response only in deficiency of Yin(陰虛) and the rate of high response in stagnation of the liver-qi's fire-transmission(肝變化火) and deficiency of blood (血虛) is comparatively high. Result of Graph R is that the rate of high response in wind-heat(風熱), deficiency of blood(血虛) and plegm syncope(痰厥) is comparatively higher than in others.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.2031-2033
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• 2016

Background: Symptomatic multiple myeloma (MM) is an acquired B-cell malignant proliferation of antibody secreting plasma cells, characterized by end organ damage due to monoclonal immunoglobulin secretion. The aim of this study wa to determine the stage stratification according to an international scoring system in adult Pakistani MM patients at presentation. Materials and Methods: This single centre retrospective study extendedfrom January 2012 to December 2015. Data were retrieved from the departmental maintained records. Results: A total of 39 patients were diagnosed at our center with MM during the period of the study, 25 males and 14 females. Age ranged between 36 and 81 with a mean of $54.5{\pm}14.8$ and a median of 57 years. Common presenting complaints included fatigue (80.9%), backache (79.3%) and bone pain (66.2%). Overall, 9 patients were in ISS stage I (23%), 12 were in stage II (30.7%) and 18 were in stage III (46.1%). Out of the total, 29 (74.3%) had kappa immunoglobulin andthe remaining 10 (25.6%) had lambda type myelomas. IgG myeloma was commonest, seen in 26 (66.6%) followed by IgA in 11 (28.2%) with non secretory myeloma in one (2.5%) and light chain disease also in one patient (2.5%). Conclusions: MM in Pakistani patients is seen in a relatively young population with male predominance. Primarily patients are symptomatic and risk stratification revealed a predominance of advanced stage III disease in our setting.