• 디지털융복합연구
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• 제19권9호
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• pp.257-269
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• 2021

논문은 심탄도(BCG, Ballistocardiogram) 센서를 이용하여 생체신호 데이터를 비침습, 무구속적인 방식으로 수집하고, ICT 기술과 고성능 컴퓨팅 환경에서 인공지능 기계학습 알고리즘을 활용하여 데이터 기반 혈당 예측 알고리즘 모델 개발 및 검증하는 방법을 제시하고 연구하는 것이다. 혈당수치 예측모델은 MLP 아키텍처에 입력노드는 심박수, 호흡수, 심박출량, 심박변이도, SDNN, RMSSD, PNN50, 나이, 성별이며, 은닉층 7개를 사용하였다. 실험 결과는 5회 실험한 학습데이터의 평균 MSE, MAE 및 RMSE 값은 각각 0.5226, 0.6328 및 0.7692이며 검증데이터 평균 값은 각각 0.5408, 0.6776, 0.7968이었으며, 결정계수(R2) 수치는 0.9997의 결과를 보였다. 데이터를 기반으로 한 혈당수치를 예측하는 모델을 표준화하고 데이터셋 수집과 예측 정확성을 검증하는 연구가 계속적으로 진행된다면 비침습 방식의 혈당 수준 관리에 활용될 수 있을 것으로 사료된다.

• 기본간호학회지
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• 제16권1호
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• pp.6-13
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• 2009

Purpose: The purpose of this study was to identify differences in blood pressure according to cuff size and measurement sites of the participants. Method: The participants consisted of 50 women and 50 men whose upper arm circumference was $26\sim30cm$. They had no chronic illness and gave consent to participate. Blood pressure of the wrist was measured in the sitting position, the upper arm with a standard cuff, large and small cuffs were used for measurement in supine position and the thigh in prone position. The data were analyzed with paired t-test using SPSS 12.0 program. Result: The data for the upper arm showed a difference in systolic and diastolic blood pressure depending on the site of measurement. There was a significant difference between measurements with a standard cuff and measurements with large and small cuffs. The systolic blood pressure of the wrist and the thigh were significantly lower than that of the upper arm. Conclusion: These results suggest that the selection of an appropriate cuff is an essential element in ensuring accuracy when measuring blood pressure and differences in systolic blood pressure for the upper arm, wrist and thigh indicate the need to record the measuring site when measuring blood pressure.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.1923-1929
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• 2003

The present study investigated the microcirculation of blood in the left common artery (LCCA). In order to develop a mathematical model for microcirculation in LCCA, the present study adopted preexisted set of measured morphological data on anatomy, mechanical properties of the coronary vessels, viscosity of blood, the basic laws of physics, and the appropriate boundary conditions. In this study, the statistical distribution of blood pressure, blood flow, and blood volume in the LCCA were determined based on the anatomical branching pattern of the coronary arterial tree and the statistical data of blood vessel dimensions. Our calculations were in good agreement with the previous studies. The present results showed that the mean longitudinal pressure drop profile was function of the vessel order numbers. It was found that the normalized pressure drop was a logarithmic function of the compliance.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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• pp.380-382
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• 2007

As the society changes more to the aging society in future, many healthcare product are developed and distributed more on the market. The digital wrist band tye blood pressure device for home use are popular already in the market. It is useful for checking blood pressure level at home and control of hypertension. Especially. It is very essential home device to check the health condition of blood circulation disease. Nowadays many product types are available. But the measurement accuracy of blood pressure is not enough compared to the mechanical type. It needs to be upgraded to assure the precise health data enough to use in the hospital. The structure, feature and output signal of capacitor type pressure sensors are analyzed. An improved design fa capacitor sensor is suggested. It shows more precise health data after use on a wrist band type health unit. They can be applied for remote u-health medical service.

• Journal of Ginseng Research
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• 제34권2호
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• pp.132-137
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• 2010

Lead (Pb) is a metal that is generally considered to be toxic to the cardiovascular system. Pb-exposed animals display the evidence of increased oxidative stress and hypertension. The current study was designed to examine whether Korean red ginseng (KRG) has protective effects against Pb-induced hypertension and oxidative stress in Pb-exposed rats. Male Sprague-Dawley rats were randomly assigned to Pb exposure or control groups. KRG was administered in drinking water at a concentration of 100 mg/kg/day; the control group received plain drinking water. Animals in the Pb-exposed groups were provided with drinking water containing 100 ppm Pb acetate for 12 weeks. Blood pressure, plasma glutathione, blood Pb concentration, and hematologic data, such as red blood cell quantity, were determined. Pb poisoning was assessed by measuring the blood Pb concentration. Pb exposure (100 ppm) for 12 weeks resulted in a marked rise in systolic blood pressure and blood Pb concentration, as well as a significant reduction in plasma glutathione levels and red blood cell quantity. Other measurements, such as heart rate, body weight, and white blood cell quantity, were unchanged. Treatment with KRG significantly lowered blood pressure, raised plasma glutathione and increased red blood cell numbers in Pb-exposed animals; it also had no effect on heart rate, body weight, or white blood cell quantity. However, the elevated blood Pb concentration was not reduced by treatment with KRG (100 mg/kg). Taken together, these data indicate that treatment with KRG in Pb-exposed animals can reduce oxidative stress and lower blood pressure, suggesting that KRG might be protective against Pb-exposed hypertension and oxidative stress.

• IMMUNE NETWORK
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• 제3권2호
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• pp.83-88
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• 2003

The number of umbilical cord blood transplantation is increasing worldwide as it has expanded the ability of the transplantaion community to meet the growing needs of their patients. Clinical data over the last decade show promising results in transplantation using both related as well as unrelated cord bloods. Cord blood banks are essential for the clinical use for transplantation and are now established around the world with the major efforts to standardize banking in collection, processing and distribution of cord blood for providing the highest quality stem cells for the patients. In Korea, Medipost, Histostem and some regional cord blood banks were established some years ago and collected thousands of cord blood for public but it had some limitations and was not expanded as the cord blood transplantation was not covered by medical insurance. Recently with the change in the policy of medical insurance to cover the cord blood transplantation, several venture companies are showing great interests in cord blood banking and trying to establish private cord blood banks in Korea. This review article discusses the current status of cord blood transplantaion and also the clincial use of stem cells from cord blood.

• 한국보건간호학회지
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• 제23권2호
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• pp.285-295
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• 2009

Purpose: This study surveyed first-year college students on their knowledge of hypertension and their health behavior to obtain basic data necessary to develop hypertension prevention and management programs. Method: Subjects were 561 first-year students at a college in Chungcheongbuk-do, Korea. Data was collected using a structured questionnaire during the period from 01 October to 08 December 2007. Data analysis involved t-test, ANOVA, and Pearson correlation coefficient using SPSS for Windows. Results: Of the total subjects, 149 (26.6%) had a family history of hypertension 253 (45.1%) knew their blood pressure, 365 (65.9%) did not measure blood pressure, and 388 (69.1%) were not interested in knowing their blood pressure. Subjects' knowledge related to hypertension averaged 11.54 points out of 22, hypertension-related health behavior averaged 2.31 points out of 4. With a higher score indicative of increased attention paid to healthy behavior. Conclusion: Knowledge of blood pressure and characteristics of hypertension and management of both blood pressure and hypertension can be inadequate in first-year college students. Increased knowledge of hypertension may lead to better health behavior.

• 한국실내디자인학회논문집
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• 제14권6호
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• pp.140-147
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• 2005

For a safe and stable supply of blood in Korea, 'Blood Donation Houses' are springing up all over Korea to advertise and improve the awareness on blood donations. This research will conduct a study on such blood donation centers, their conditions and problems. It will furthermore provide solutions to raise the level of comfort to donators and help nurses for a better working environment. The research will be conducted in 'Blood Donation Houses' that were established by 4 centers of the Korean Red Cross in Seoul after 1993. Any houses that are temporary (containers, buses, smaller than 15 pyung) were excluded from this study. In order to investigate changes of these houses, the ones analyzed and recorded in the 2002 data were used as a basis for comparison. A total of 16 houses were selected for this study. 5 houses were closed after the initial study of 2002, and 6 houses were not available for research upon above mentioned criteria, leaving 9 houses from the original 2002 data. 7 additional houses were opened after 2002, which were included in this study. The research was conducted by a close study of written materials on the historical and theoretical viewpoint of blood donations, as well as visits to the actual Blood Donation Houses. The conclusion will offer solutions to necessary functional and working space, and lighting in such houses on the basis of above analyzed theoretical and practical data.

• 융합정보논문지
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• 제10권11호
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• pp.232-239
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• 2020

본 연구의 목적은 대학생의 헌혈참여 동기에 영향을 미치는 요인을 파악하기 위해 실시되었다. 연구대상자는 일 지역의 대학생 200명으로 하였으며, 자료수집은 자가보고 설문지를 활용하였다. 자료분석은 빈도, 백분율, 평균, 표준편차, 독립표본 T검정, 일원배치 분산분석(One way ANOVA), 피어슨의 상관계수(Pearson Correlation Coefficient), 다중회귀분석(Multiple Regression Analysis)을 사용하였다. 연구결과 대상자의 헌혈참여 동기에 영향을 미치는 요인은 헌혈에 대한 태도, 향후 헌혈참여 계획, 지각된 건강상태, 이타성, 헌혈경험 횟수의 순으로 유의하게 나타났다. 본 연구결과는 대학생의 헌혈참여 동기를 높이기 위한 교육프로그램 개발에 기초자료로 활용될 수 있을 것이다. 또한 대학생의 헌혈에 대한 태도, 이타성 및 건강상태를 높여 줄 수 있는 전략 개발이 필요함을 시사한다.

• 대한기계학회논문집B
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• 제30권4호
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• pp.314-319
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• 2006

To analyze in-vivo blood flow characteristics in a chicken embryo, in-vivo experiment was carried out using micro-PIV technique. Because endothelial cells in blood vessels are subject to shear stress of blood flow, it is important to get velocity field information of the placental blood flow. Instantaneous velocity fields of an extraembryonic blood vessel using a high-speed camera and intravital microscope. The flow images of RBCs were obtained with a spatial resolution of $20\times20{\mu}m$ in the whole blood vessels. The mean velocity field data confirm that the blood flow does show non-Newtonian fluid characteristic. The blood in a branched vessel merged smoothly without any flow separation into the main blood vessel with the presence of a slight bump. This in-vivo micro-PIV measurement technique can be used as a powerful tool in various blood flow researches.